Augmented anticancer activity of a targeted, intracellularly activatable, theranostic nanomedicine based on fluorescent and radiolabeled, methotrexate-folic acid-multiwalled carbon nanotube conjugate

Molecular Pharmaceutics

Volumn 10, Issue 7, 2013, Pages 2543-2557

  Das, Manasmita ^a   Datir, Satyajit R ^a   Singh, Raman Preet ^a   Jain, Sanyog ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

cancer; folate receptor mediated endocytosis; methotrexate; multiwalled carbon nanotubes; scintigraphy; tumor targeted delivery

Indexed keywords

ESTER; FLUOROCHROME; FOLATE RECEPTOR; FOLIC ACID; METHOTREXATE; MULTI WALLED NANOTUBE; PERTECHNETIC ACID TC 99M; RADIOISOTOPE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CANCER GROWTH; CARDIOTOXICITY; COMPUTER MODEL; CONTROLLED STUDY; DRUG FORMULATION; DRUG RELEASE; DRUG SYNTHESIS; DRUG TARGETING; ENDOCYTOSIS; FEMALE; HUMAN; HUMAN CELL; IC 50; ISOTOPE LABELING; LIVER TOXICITY; LYSOSOME; NANOMEDICINE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SCINTIGRAPHY; TREATMENT RESPONSE; TUMOR GROWTH; XENOGRAFT;

CELL LINE, TUMOR; DRUG DELIVERY SYSTEMS; ENDOCYTOSIS; FOLIC ACID; HUMANS; METHOTREXATE; NANOMEDICINE; NANOTUBES, CARBON;

EID: 84879696853     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp300701e     Document Type: Article

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