Microbiologically active Mannich bases derived from 1,2,4-triazoles. the effect of C-5 substituent on antibacterial activity

Medicinal Chemistry Research

Volumn 22, Issue 5, 2013, Pages 2531-2537

  Plech, Tomasz ^a   Wujec, Monika ^a   Majewska, Magdalena ^a   Kosikowska, Urszula ^a   Malm, Anna ^a  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

Author keywords

Aminomethylation; Five membered ring; MRSA; Opportunistic bacteria

Indexed keywords

1,2,4 TRIAZOLE DERIVATIVE; 4 (4 BROMOPHENYL) 2 (MORPHOLIN 4 YLMETHYL) 5 PHENYL 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 4 (4 BROMOPHENYL) 2 [(DIETHYLAMINO)METHYL] 5 PHENYL 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 4 (4 BROMOPHENYL) 5 (2 CHLOROPHENYL) 2 (MORPHOLIN 4 YLMETHYL) 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 4 (4 BROMOPHENYL) 5 (2 CHLOROPHENYL) 2 (PIPERIDIN 1 YLMETHYL) 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 4 (4 BROMOPHENYL) 5 (2 CHLOROPHENYL) 2 (PYRROLIDIN 1 YLMETHYL) 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 4 (4 BROMOPHENYL) 5 (2 CHLOROPHENYL) 2 [(DIETHYLAMINO)METHYL] 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 4 (4 BROMOPHENYL) 5 (4 CHLOROPHENYL) 2 (MORPHOLIN 4 YLMETHYL) 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 4 (4 BROMOPHENYL) 5 (4 CHLOROPHENYL) 2 (PIPERIDIN 1 YLMETHYL) 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 4 (4 BROMOPHENYL) 5 (4 CHLOROPHENYL) 2 (PYRROLIDIN 1 YLMETHYL) 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 4 (4 BROMOPHENYL) 5 (4 CHLOROPHENYL) 2 [(DIETHYLAMINO)METHYL] 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 4 (4 BROMOPHENYL) 5 PHENYL 2 (PIPERIDIN 1 YLMETHYL) 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 4 (4 BROMOPHENYL) 5 PHENYL 2 (PYRROLIDIN 1 YLMETHYL) 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; AMPICILLIN; CEFUROXIME; CHLORINE; HYDRAZIDE DERIVATIVE; MANNICH BASE; THIOSEMICARBAZIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACILLUS CEREUS; BACILLUS SUBTILIS; CARBON NUCLEAR MAGNETIC RESONANCE; CONCENTRATION RESPONSE; CYCLIZATION; IN VITRO STUDY; MANNICH REACTION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHYSICAL CHEMISTRY; PROTON NUCLEAR MAGNETIC RESONANCE; STAPHYLOCOCCUS AUREUS;

EID: 84879686919     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-012-0248-y     Document Type: Article

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