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Volumn 24, Issue 6, 2004, Pages 3923-3929

Characterization of the glutametergic system in MG-63 osteoblast-like osteosarcoma cells

Author keywords

Glutamate transporters; Glutamine synthetase; Ionotropic glutamate receptors; Metabotropic glutamate receptors; MG 63 cells

Indexed keywords

GLUTAMATE AMMONIA LIGASE; GLUTAMATE RECEPTOR; GLUTAMATE TRANSPORTER; GLUTAMIC ACID; GLUTAMINE; IONOTROPIC RECEPTOR; MESSENGER RNA; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR 2; METABOTROPIC RECEPTOR 3; METABOTROPIC RECEPTOR 4; METABOTROPIC RECEPTOR 5; METABOTROPIC RECEPTOR 6; METABOTROPIC RECEPTOR 7; METABOTROPIC RECEPTOR 8; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2C; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2D; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 3A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 3B; UNCLASSIFIED DRUG; COTRANSPORTER; EXCITATORY AMINO ACID TRANSPORTER 1; ISOPROTEIN; NR1 NMDA RECEPTOR; SLC1A3 PROTEIN, HUMAN;

EID: 14944381280     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (47)

References (56)
  • 1
    • 0024322576 scopus 로고
    • In vivo stimulation of bone formation by transforming growth factor-beta
    • Noda M and Camilliere JJ: In vivo stimulation of bone formation by transforming growth factor-beta. Endocrinology 124: 2991-2994, 1989.
    • (1989) Endocrinology , vol.124 , pp. 2991-2994
    • Noda, M.1    Camilliere, J.J.2
  • 3
    • 0025756370 scopus 로고
    • Effects of transforming growth factor-beta and IL-1 alpha on prostaglandin synthesis in serum-deprived osteoblastic cells
    • Marusic A, Kalinowski JF, Harrison JR, Centrella M, Raisz LG and Lorenzo JA: Effects of transforming growth factor-beta and IL-1 alpha on prostaglandin synthesis in serum-deprived osteoblastic cells. J Immunol 146: 2633-2638, 1991.
    • (1991) J Immunol , vol.146 , pp. 2633-2638
    • Marusic, A.1    Kalinowski, J.F.2    Harrison, J.R.3    Centrella, M.4    Raisz, L.G.5    Lorenzo, J.A.6
  • 4
    • 0025923792 scopus 로고
    • Prostaglandin E2 stimulates insulin-like growth factor I synthesis in osteoblast-enriched cultures from fetal rat bone
    • McCarthy TL, Centrella M, Raisz LG and Canalis E: Prostaglandin E2 stimulates insulin-like growth factor I synthesis in osteoblast-enriched cultures from fetal rat bone. Endocrinology 128: 2895-2900, 1991.
    • (1991) Endocrinology , vol.128 , pp. 2895-2900
    • McCarthy, T.L.1    Centrella, M.2    Raisz, L.G.3    Canalis, E.4
  • 5
    • 0028261047 scopus 로고
    • Human osteoblast-like cells produce nitric oxide and express inducible nitric oxide synthase
    • Ralston SH, Todd D, Helfrich MH, Benjamin N and Grabowski P: Human osteoblast-like cells produce nitric oxide and express inducible nitric oxide synthase. Endocrinology 135: 330-336, 1994.
    • (1994) Endocrinology , vol.135 , pp. 330-336
    • Ralston, S.H.1    Todd, D.2    Helfrich, M.H.3    Benjamin, N.4    Grabowski, P.5
  • 6
    • 0030717452 scopus 로고    scopus 로고
    • Interaction between nitric oxide synthase and cyclooxygenase pathways in osteoblastic MC3T3-E1 cells
    • Kanematsu M, Ikeda K and Yamada Y: Interaction between nitric oxide synthase and cyclooxygenase pathways in osteoblastic MC3T3-E1 cells. J Bone Miner Res 12: 1789-1796, 1997.
    • (1997) J Bone Miner Res , vol.12 , pp. 1789-1796
    • Kanematsu, M.1    Ikeda, K.2    Yamada, Y.3
  • 7
    • 0032924033 scopus 로고    scopus 로고
    • Signal transduction pathways involved in fluid flow-induced PGE2 production by cultured osteocytes
    • Ajubi NE, Klein-Nulend J, Alblas MJ, Burger EH and Nijweide PJ: Signal transduction pathways involved in fluid flow-induced PGE2 production by cultured osteocytes. Am J Physiol 276: E171-178, 1999.
    • (1999) Am J Physiol , vol.276
    • Ajubi, N.E.1    Klein-Nulend, J.2    Alblas, M.J.3    Burger, E.H.4    Nijweide, P.J.5
  • 9
    • 0006321016 scopus 로고    scopus 로고
    • Regulated glutamate exocytosis in osteoblasts
    • Genever PG and Skerry TM: Regulated glutamate exocytosis in osteoblasts. Calcif Tissue Int O-30(Suppl 1): S57, 2000.
    • (2000) Calcif Tissue Int , vol.O-30 , Issue.SUPPL. 1
    • Genever, P.G.1    Skerry, T.M.2
  • 10
    • 4243503469 scopus 로고    scopus 로고
    • Regulated glutamate exocytosis is necessary for osteoblast differentiation and survival in vitro
    • Genever PG and Skerry TM: Regulated glutamate exocytosis is necessary for osteoblast differentiation and survival in vitro. J Bone Miner Res SU191(Suppl 1): S378, 2000.
    • (2000) J Bone Miner Res , vol.SU191 , Issue.SUPPL. 1
    • Genever, P.G.1    Skerry, T.M.2
  • 12
    • 0036125234 scopus 로고    scopus 로고
    • Osteoblastic glutamate receptor function regulates bone formation and resorption
    • Taylor AF: Osteoblastic glutamate receptor function regulates bone formation and resorption. J Musculoskel Neuron Interact 2: 285-290, 2002.
    • (2002) J Musculoskel Neuron Interact , vol.2 , pp. 285-290
    • Taylor, A.F.1
  • 13
    • 85103140291 scopus 로고    scopus 로고
    • Glutamatergic system in bone physiology
    • in press
    • Kalariti N and Koutsilieris M: Glutamatergic system in bone physiology. In Vivo (in press).
    • In Vivo
    • Kalariti, N.1    Koutsilieris, M.2
  • 14
    • 0022930506 scopus 로고
    • Localization of 3H glutamate bindingsites in rat adrenal-medulla
    • Yoneda Y and Ogita K: Localization of 3H glutamate bindingsites in rat adrenal-medulla. Brain Res 383: 387-391, 1986.
    • (1986) Brain Res , vol.383 , pp. 387-391
    • Yoneda, Y.1    Ogita, K.2
  • 15
    • 0024398583 scopus 로고
    • Glutamate receptors of the NMDA subtype in the myenteric plexus of the guinea-pig ileum
    • Shannon HE and Sawyer BD: Glutamate receptors of the NMDA subtype in the myenteric plexus of the guinea-pig ileum. J Pharmacol Exp Ther 251: 518-523, 1989.
    • (1989) J Pharmacol Exp Ther , vol.251 , pp. 518-523
    • Shannon, H.E.1    Sawyer, B.D.2
  • 16
    • 0030029791 scopus 로고    scopus 로고
    • Excitotoxicity in the lung NMDA induced, nitric oxide-dependent, pulmonary-edema is attenuated by VIP and by inhibitors of poly(adp-ribose) polymerase
    • Said SI, Berisha HI and Pakbaz H: Excitotoxicity in the lung NMDA induced, nitric oxide-dependent, pulmonary-edema is attenuated by VIP and by inhibitors of poly(adp-ribose) polymerase. Proc Natl Acad Sci USA 93: 4688-4692, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 4688-4692
    • Said, S.I.1    Berisha, H.I.2    Pakbaz, H.3
  • 18
    • 0030948207 scopus 로고    scopus 로고
    • Mechanically regulated expression of a neural glutamate transporter in bone: A role for excitatory amino acids as osteotropic agents?
    • Mason DJ, Suva LJ, Genever PG, Patton AJ, Steuckle S, Hillam RA and Skerry TM: Mechanically regulated expression of a neural glutamate transporter in bone: a role for excitatory amino acids as osteotropic agents? Bone 20: 199-205, 1997.
    • (1997) Bone , vol.20 , pp. 199-205
    • Mason, D.J.1    Suva, L.J.2    Genever, P.G.3    Patton, A.J.4    Steuckle, S.5    Hillam, R.A.6    Skerry, T.M.7
  • 19
    • 0035313223 scopus 로고    scopus 로고
    • Glutamate signalling in non-neuronal tissues
    • Skerry TM and Genever PG: Glutamate signalling in non-neuronal tissues. Trends Pharmacol Sci 22: 174-181, 2001.
    • (2001) Trends Pharmacol Sci , vol.22 , pp. 174-181
    • Skerry, T.M.1    Genever, P.G.2
  • 20
    • 0036718462 scopus 로고    scopus 로고
    • Functional osteoblastic ionotropic glutamate receptors are a prerequisite for bone formation
    • Taylor AF: Functional osteoblastic ionotropic glutamate receptors are a prerequisite for bone formation. J Musculoskel Neuron Interact 2: 415-422, 2002.
    • (2002) J Musculoskel Neuron Interact , vol.2 , pp. 415-422
    • Taylor, A.F.1
  • 21
    • 0032763911 scopus 로고    scopus 로고
    • The glutamate receptor antagonist MK801 modulates bone resorption by a mechanism predominantly involving osteoclast differentiation
    • Peet NM, Grabowski PS, Laketic LI and Skerry TM: The glutamate receptor antagonist MK801 modulates bone resorption by a mechanism predominantly involving osteoclast differentiation. FASEB J 13: 2179-2185, 1999.
    • (1999) FASEB J , vol.13 , pp. 2179-2185
    • Peet, N.M.1    Grabowski, P.S.2    Laketic, L.I.3    Skerry, T.M.4
  • 22
    • 0024596865 scopus 로고
    • The excitatory amino acid receptors: Their classes, pharmacology, and distinct properties in the function of the central nervous system
    • Monaghan DT, Bridges RJ and Cotman CW: The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous system. Annu Rev Pharmacol Toxicol 29: 365-402, 1989.
    • (1989) Annu Rev Pharmacol Toxicol , vol.29 , pp. 365-402
    • Monaghan, D.T.1    Bridges, R.J.2    Cotman, C.W.3
  • 24
    • 0032486422 scopus 로고    scopus 로고
    • The tetrameric structure of a glutamate receptor channel
    • Rosenmund C, Stern-Bach Y and Stevens CF: The tetrameric structure of a glutamate receptor channel. Science 280: 1596-1599, 1998.
    • (1998) Science , vol.280 , pp. 1596-1599
    • Rosenmund, C.1    Stern-Bach, Y.2    Stevens, C.F.3
  • 25
    • 0033578892 scopus 로고    scopus 로고
    • Biochemical evidence for the co-association of three N-methyl-D-aspartate (NMDA) R2 subunits in recombinant NMDA receptors
    • Hawkins LM, Chazot PL and Stephensen FA: Biochemical evidence for the co-association of three N-methyl-D-aspartate (NMDA) R2 subunits in recombinant NMDA receptors. J Biol Chem 274: 27211-27218, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 27211-27218
    • Hawkins, L.M.1    Chazot, P.L.2    Stephensen, F.A.3
  • 33
    • 0026093312 scopus 로고
    • Sequence and expression of a metabotropic glutamate receptor
    • Masu M, Tanabe Y, Tsuchida K, Shigemoto R and Nakanishi S: Sequence and expression of a metabotropic glutamate receptor. Nature 349: 760-765, 1991.
    • (1991) Nature , vol.349 , pp. 760-765
    • Masu, M.1    Tanabe, Y.2    Tsuchida, K.3    Shigemoto, R.4    Nakanishi, S.5
  • 34
    • 0026489330 scopus 로고
    • Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain
    • Storck T, Schulte S, Hofmann K and Stoffel W: Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain. Proc Natl Acad Sci USA 89: 10955-10959, 1992.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 10955-10959
    • Storck, T.1    Schulte, S.2    Hofmann, K.3    Stoffel, W.4
  • 35
    • 0027328158 scopus 로고
    • Cloning and expression of a glutamate transporter from mouse brain
    • Tanaka K: Cloning and expression of a glutamate transporter from mouse brain. Neurosci Lett 759: 183-186, 1993.
    • (1993) Neurosci Lett , vol.759 , pp. 183-186
    • Tanaka, K.1
  • 37
    • 0026458124 scopus 로고
    • Primary structure and functional characterization of a high-affinity glutamate transporter
    • Kanai Y and Hediger MA: Primary structure and functional characterization of a high-affinity glutamate transporter. Nature 560: 467-471, 1992
    • (1992) Nature , vol.560 , pp. 467-471
    • Kanai, Y.1    Hediger, M.A.2
  • 38
    • 0029076899 scopus 로고
    • An excitatory amino-acid transporter with properties of a ligand-gated chloride channel
    • Fairman WA, Vandenberg RJ, Arriza JL, Kavanaugh MP and Amara SG: An excitatory amino-acid transporter with properties of a ligand-gated chloride channel. Nature 375: 599-603, 1995.
    • (1995) Nature , vol.375 , pp. 599-603
    • Fairman, W.A.1    Vandenberg, R.J.2    Arriza, J.L.3    Kavanaugh, M.P.4    Amara, S.G.5
  • 39
    • 0030932152 scopus 로고    scopus 로고
    • Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance
    • Arriza JL, Eliasof S, Kavanaugh MP and Amara SG: Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance. Proc Natl Acad Sci USA 8: 4155-4160, 1997.
    • (1997) Proc Natl Acad Sci USA , vol.8 , pp. 4155-4160
    • Arriza, J.L.1    Eliasof, S.2    Kavanaugh, M.P.3    Amara, S.G.4
  • 40
    • 0000221157 scopus 로고
    • Catalytic mechanism of glutamine synthetase: Overview of glutamine metabolism
    • (Mora J and Palacios R, eds). New York, NY, USA, Academic Press
    • Meister A: Catalytic mechanism of glutamine synthetase: Overview of glutamine metabolism. In: The Glutamine Metabolism, Enzymology, and Regulation (Mora J and Palacios R, eds). New York, NY, USA, Academic Press. 1980, pp 1-40.
    • (1980) The Glutamine Metabolism, Enzymology, and Regulation , pp. 1-40
    • Meister, A.1
  • 41
    • 0022272445 scopus 로고
    • Glutamine synthetase from mammalian tissues
    • (Colowick SP, Kaplan NO and Meister A, eds). New York, NY, USA, Academic Press
    • Meister A: Glutamine synthetase from mammalian tissues. In: Methods in Enzymology (Colowick SP, Kaplan NO and Meister A, eds). New York, NY, USA, Academic Press. 1985, vol. 113 pp 185-199.
    • (1985) Methods in Enzymology , vol.113 , pp. 185-199
    • Meister, A.1
  • 42
    • 0030588067 scopus 로고    scopus 로고
    • Chromosomal mapping of a family of human glutamine synthetase genes: Functional gene (GLUL) on 1q25, pseudogene (GLULP) on 9p13, and three related genes (GLULL1, GLULL2, GLULL3) on 5q33, 11p15, and 11q24
    • Wang Y, Kudoh J, Kubota R, Asakawa S, Minoshima S and Shimizu N: Chromosomal mapping of a family of human glutamine synthetase genes: functional gene (GLUL) on 1q25, pseudogene (GLULP) on 9p13, and three related genes (GLULL1, GLULL2, GLULL3) on 5q33, 11p15, and 11q24. Genomics 37: 195-199, 1996.
    • (1996) Genomics , vol.37 , pp. 195-199
    • Wang, Y.1    Kudoh, J.2    Kubota, R.3    Asakawa, S.4    Minoshima, S.5    Shimizu, N.6
  • 45
    • 0036715398 scopus 로고    scopus 로고
    • Glutamatergic regulation of bone resorption
    • Chenu C: Glutamatergic regulation of bone resorption. J Musculoskel Neuron Interact 2: 423-431, 2002.
    • (2002) J Musculoskel Neuron Interact , vol.2 , pp. 423-431
    • Chenu, C.1
  • 46
    • 0032979402 scopus 로고    scopus 로고
    • Identification of novel signaling pathways during functional adaptation of the skeleton to mechanical loading: The role of glutamate as a paracrine signaling agent in the skeleton
    • Skerry TM: Identification of novel signaling pathways during functional adaptation of the skeleton to mechanical loading: the role of glutamate as a paracrine signaling agent in the skeleton. J Bone Miner Metab 77: 66-70, 1999.
    • (1999) J Bone Miner Metab , vol.77 , pp. 66-70
    • Skerry, T.M.1
  • 48
    • 0041703024 scopus 로고    scopus 로고
    • Modulation of cellular differentiation by N-methyl-D-aspartate receptors in osteoblasts
    • Hinoi E, Fujimori S and Yoneda Y: Modulation of cellular differentiation by N-methyl-D-aspartate receptors in osteoblasts. Faseb J 17: 1532-1534, 2003.
    • (2003) FASEB J , vol.17 , pp. 1532-1534
    • Hinoi, E.1    Fujimori, S.2    Yoneda, Y.3
  • 49
    • 0032055026 scopus 로고    scopus 로고
    • Glutamate receptors are expressed by bone cells and are involved in bone resorption
    • Chenu C, Serre CM, Raynal C, Burt-Pichat B and Delmas PD: Glutamate receptors are expressed by bone cells and are involved in bone resorption. Bone 22: 295-299, 1998.
    • (1998) Bone , vol.22 , pp. 295-299
    • Chenu, C.1    Serre, C.M.2    Raynal, C.3    Burt-Pichat, B.4    Delmas, P.D.5
  • 50
    • 0034607082 scopus 로고    scopus 로고
    • Specific antagonists of NMDA receptors prevent osteoclast sealing zone formation required for bone resorption
    • Itzstein C, Espinosa L, Delmas PD and Chenu C: Specific antagonists of NMDA receptors prevent osteoclast sealing zone formation required for bone resorption. Biochem Biophys Res Commun 268: 201-209, 2000.
    • (2000) Biochem Biophys Res Commun , vol.268 , pp. 201-209
    • Itzstein, C.1    Espinosa, L.2    Delmas, P.D.3    Chenu, C.4
  • 51
    • 0029887725 scopus 로고    scopus 로고
    • Subtype-specific regulation of recombinant NMDA receptor channels by protein tyrosine kinases of the Src family
    • Kohr G and Seeburg PH: Subtype-specific regulation of recombinant NMDA receptor channels by protein tyrosine kinases of the Src family. J Physiol 492: 445-452, 1996.
    • (1996) J Physiol , vol.492 , pp. 445-452
    • Kohr, G.1    Seeburg, P.H.2
  • 52
    • 0026612467 scopus 로고
    • Requirement of pp60c-Src expression for osteoclasts to form ruffled borders and resorb bone in mice
    • Boyce BF, Yoneda T, Lowe C, Soriano P and Mundy GR: Requirement of pp60c-Src expression for osteoclasts to form ruffled borders and resorb bone in mice. J Clin Invest 90: 1622-1627, 1992.
    • (1992) J Clin Invest , vol.90 , pp. 1622-1627
    • Boyce, B.F.1    Yoneda, T.2    Lowe, C.3    Soriano, P.4    Mundy, G.R.5
  • 53
    • 0034802981 scopus 로고    scopus 로고
    • Group III metabotropic glutamate receptors in rat cultured calvarial osteoblasts
    • Hinoi E, Fujimori S, Nakamura Y and Yoneda Y: Group III metabotropic glutamate receptors in rat cultured calvarial osteoblasts. Biochem Biophys Res Commun 281: 341-346, 2001.
    • (2001) Biochem Biophys Res Commun , vol.281 , pp. 341-346
    • Hinoi, E.1    Fujimori, S.2    Nakamura, Y.3    Yoneda, Y.4
  • 54
    • 0034602266 scopus 로고    scopus 로고
    • Expression of functional metabotropic glutamate receptors in primary cultured rat osteoblasts. Cross-talk with N-methyl-D-aspartate receptors
    • Gu Y and Publicover SJ: Expression of functional metabotropic glutamate receptors in primary cultured rat osteoblasts. Cross-talk with N-methyl-D-aspartate receptors. J Biol Chem 275: 34252-34259, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 34252-34259
    • Gu, Y.1    Publicover, S.J.2
  • 55
    • 0842330734 scopus 로고    scopus 로고
    • Glucocorticoids induce glutamine synthetase expression in human osteoblastic cells: A novel observation in bone
    • Olkku A, Bodine PVN, Linnnala-Kankkunen A and Mahonen A: Glucocorticoids induce glutamine synthetase expression in human osteoblastic cells: a novel observation in bone. Bone 34: 320-329, 2004.
    • (2004) Bone , vol.34 , pp. 320-329
    • Olkku, A.1    Bodine, P.V.N.2    Linnnala-Kankkunen, A.3    Mahonen, A.4


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