Microinjection of adenosine into the hypothalamic ventrolateral preoptic area enhances wakefulness via the A1 receptor in rats

Neurochemical Research

Volumn 38, Issue 8, 2013, Pages 1616-1623

  Zhang, Jin ^a   Yin, Dou ^a   Wu, Fang ^a   Zhang, Gongliang ^a   Jiang, Chuanwei ^a   Li, Zhen ^a   Wang, Liecheng ^a   Wang, Kai ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

Adenosine; Rat; Sleep; Ventrolateral preoptic area

Indexed keywords

8 CYCLOPENTYLTHEOPHYLLINE; ADENOSINE; ADENOSINE A1 RECEPTOR; CYCLOHEXYLADENOSINE; NITROBENZYLTHIOINOSINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTROENCEPHALOGRAM; ELECTROMYOGRAM; HISTOLOGY; HYPOTHALAMIC VENTROLATERAL PREOPTIC AREA; HYPOTHALAMUS; MALE; MICROINJECTION; NONHUMAN; NONREM SLEEP; PREOPTIC AREA; PRIORITY JOURNAL; PROTEIN EXPRESSION; REM SLEEP; SLEEP WAKING CYCLE; WAKEFULNESS;

ADENOSINE; ANIMALS; MALE; MICROINJECTIONS; PREOPTIC AREA; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ADENOSINE A1; WAKEFULNESS;

RATTUS;

EID: 84879686272     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-013-1063-7     Document Type: Article

References (44)

1. Feldberg W, Sherwood SL (1954) Injections of drugs into the lateral ventricle of the cat. J Physiol 123:148-167
2. Radulovacki M, Virus RM, Djuricic-Nedelson M, Green RD (1984) Adenosine analogs and sleep in rats. J Pharmacol Exp Ther 228:268-274
3. Schwierin B, Borbély AA, Tobler I (1996) Effects of N6-cyclopentyladenosine and caffeine on sleep regulation in the rat. Eur J Pharmacol 300:163-171
4. Portas CM, Thakkar M, Rainnie DG, Greene RW, McCarley RW (1997) Role of adenosine in behavioral state modulation: a microdialysis study in the freely moving cat. Neuroscience 79:225-235
5. Yanik G, Glaum S, Radulovacki M (1987) The dose-response effects of caffeine on sleep in rats. Brain Res 403:177-180
6. Huston JP, Haas HL, Boix F, Pfister M, Decking U, Schrader J, Schwarting RK (1996) Extracellular adenosine levels in neostriatum and hippocampus during rest and activity periods of rats. Neuroscience 73:99-107
7. Porkka-Heiskanen T, Strecker RE, McCarley RW (2000) Brain site-specificity of extracellular adenosine concentration changes during sleep deprivation and spontaneous sleep: an in vivo microdialysis study. Neuroscience 99:507-517
8. Porkka-Heiskanen T, Strecker RE, Thakkar M, Bjorkum AA, Greene RW, McCarley RW (1997) Adenosine: a mediator of the sleep-inducing effects of prolonged wakefulness. Science 276:1265-1268
9. Satoh S, Matsumura H, Koike N, Tokunaga Y, Maeda T, Hayaishi O (1999) Region-dependent difference in the sleep-promoting potency of an adenosine A2A receptor agonist. Eur J Neurosci 11:1587-1597
10. Mendelson WB (2000) Sleep-inducing effects of adenosine microinjections into the medial preoptic area are blocked by flumazenil. Brain Res 852:479-481
11. Noor-Alam M, Kumar S, Rai S, Methippara M, Szymusiak R, Mcginty D (2009) Role of adenosine A1 receptor in the perifornical-lateral hypothalamic area in sleep-wake regulation in rats. Brain Res 1304:96-104
12. Fredholm BB, IJzerman AP, Jacobson KA, Klotz KN, Linden J (2001) International Union of pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol Rev 53:527-552
13. Thakkar MM, Engemann SC, Walsh KM, Sahota PK (2008) Adenosine and the homeostatic control of sleep: effects of A1 receptor blockade in the perifornical lateral hypothalamus on sleep-wakefulness. Neuroscience 153:875-880
14. Elmenhorst D, Meyer PT, Winz OH, Matusch A, Ermert J, Coenen HH, Basheer R, Haas HL, Zilles K, Bauer A (2007) Sleep deprivation increases A1 adenosine receptor binding in the human brain: a positron emission tomography study. J Neurosci 27:2410-2415
15. Coleman CG, Baghdoyan HA, Lydic R (2006) Dialysis delivery of an adenosine A2A agonist into the pontine reticular formation of C57BL/6 J mouse increases pontine acetylcholine release and sleep. J Neurochem 96:1750-1759
16. Satoh S, Matsumura H, Suzuki F, Hayaishi O (1996) Promotion of sleep mediated by the A2a-adenosine receptor and possible involvement of this receptor in the sleep induced by prostaglandin D2 in rats. Proc Natl Acad Sci USA 93:5980-5984
17. Methippara MM, Kumar S, Alam MN, Szymusiak R, McGinty D (2005) Effects on sleep of microdialysis of adenosine A1 and A2a receptor analogs into the lateral preoptic area of rats. Am J Physiol Regul Integr Comp Physiol 289:R1715-R1723
18. Huang ZL, Qu WM, Eguchi N, Chen JF, Schwarzschild MA, Fredholm BB, Urade Y, Hayaishi O (2005) Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine. Nat Neurosci 8:858-859
19. Lu J, Greco MA, Shiromani P, Saper CB (2000) Effect of lesions of the ventrolateral preoptic nucleus on NREM and REM sleep. J Neurosci 20:3830-3842
20. Sherin JE, Shiromani PJ, McCarley RW, Saper CB (1996) Activation of ventrolateral preoptic neurons during sleep. Science 271:216-219
21. Gong H, Szymusiak R, King J, Steininger T, McGinty D (2000) Sleep-related c-Fos protein expression in the preoptic hypothalamus: effects of ambient warming. Am J Physiol Regul Integr Comp Physiol 279:R2079-R2088
22. Szymusiak R, Alam N, Steininger TL, McGinty D (1998) Sleep-waking discharge patterns of ventrolateral preoptic/anterior hypothalamic neurons in rats. Brain Res 803:178-188
23. Gong H, McGinty D, Guzman-Marin R, Chew KT, Stewart D, Szymusiak R (2004) Activation of c-fos in GABAergic neurones in the preoptic area during sleep and in response to sleep deprivation. J Physiol 556:935-946
24. Sherin JE, Elmquist JK, Torrealba F, Saper CB (1998) Innervation of histaminergic tuberomammillary neurons by GABAergic and galaninergic neurons in the ventrolateral preoptic nucleus of the rat. J Neurosci 18:4705-4721
25. Steininger TL, Gong H, McGinty D, Szymusiak R (2001) Subregional organization of preoptic area/anterior hypothalamic projections to arousal-related monoaminergic cell groups. J Comp Neurol 429:638-653
26. Yoshida K, McCormack S, España RA, Crocker A, Scammell TE (2006) Afferents to the orexin neurons of the rat brain. J Comp Neurol 494:845-861
27. Yaar R, Jones MR, Chen JF, Ravid K (2005) Animal models for the study of adenosine receptor function. J Cell Physiol 202:9-20
28. Dixon AK, Gubitz AK, Sirinathsinghji DJ, Richardson PJ, Freeman TC (1996) Tissue distribution of adenosine receptor mRNAs in the rat. Br J Pharmacol 118:1461-1468
29. Reppert SM, Weaver DR, Stehle JH, Rivkees SA (1991) Molecular cloning and characterization of a rat A1-adenosine receptor that is widely expressed in brain and spinal cord. Mol Endocrinol 5:1037-1048
30. Rivkees SA, Price SL, Zhou FC (1995) Immunohistochemical detection of A1 adenosine receptors in rat brain with emphasis on localization in the hippocampal formation, cerebral cortex, cerebellum, and basal ganglia. Brain Res 677:193-203
31. Rosin DL, Robeva A, Woodard RL, Guyenet PG, Linden J (1998) Immunohistochemical localization of adenosine A2A receptors in the rat central nervous system. J Comp Neurol 401:163-186
32. Huang ZL, Urade Y, Hayaishi O (2011) The role of adenosine in the regulation of sleep. Curr Top Med Chem 11:1047-1057
33. Zhang G, Wang L, Liu H, Zhang J (2004) Substance P promotes sleep in the ventrolateral preoptic area of rats. Brain Res 1028:225-232
34. Paxins G, Watson C (2007) The rat brain in stereotaxic coordinates. Academic Press, San Diego
35. Virus RM, Ticho S, Pilditch M, Radulovacki M (1990) A comparison of the effects of caffeine, 8-cyclopentyltheophylline, and alloxazine on sleep in rats. Possible roles of central nervous system adenosine receptors. Neuropsychopharmacology 3:243-249
36. Marks GA, Shaffery JP, Speciale SG, Birabil CG (2003) Enhancement of rapid eye movement sleep in the rat by actions at A1 and A2a adenosine receptor subtypes with a differential sensitivity to atropine. Neuroscience 116:913-920
37. Strecker RE, Morairty SR, Thakkar MM, Porkka-Heiskanen T, Basheer R, Dauphin LJ, Rainnie DG, Greene RW, McCarley RW (2000) Adenosinergic modulation of basal forebrain andpreoptic/anterior hypothalamic neuronal activity in the control of behavioral state. Behav Brain Res 115:183-204
38. Thakkar MM, Delgiacco RA, Strecker RE, McCarley RW (2003) Adenosinergic inhibition of basal forebrain wakefulness-active neurons: a simultaneous unit recording and microdialysis study in freely behaving cats. Neuroscience 122:1107-1113
39. Urade Y, Eguchi N, Qu WM, Sakata M, Huang ZL, Chen JF, Schwarzschild MA, Fink JS, Hayaishi O (2003) Sleep regulation in adenosine A2A receptor-deficient mice. Neurology 61:S94-S96
40. Ralevic V, Burnstock G (1998) Receptors for purines and pyrimidines. Pharmacol Rev 50:413-492
41. Obrietan K, Belousov AB, Heller HC, van den Pol AN (1995) Adenosine pre- and postsynaptic modulation of glutamate-dependent calcium activity in hypothalamic neurons. J Neurophysiol 74:2150-2162
42. Morairty S, Rainnie D, McCarley R, Greene R (2004) Disinhibition of ventrolateral preoptic area sleep-active neurons by adenosine: a new mechanism for sleep promotion. Neuroscience 123:451-457
43. Chamberlin NL, Arrigoni E, Chou TC, Scammell TE, Greene RW, Saper CB (2003) Effects of adenosine on gabaergic synaptic inputs to identified ventrolateral preoptic neurons. Neuroscience 119:913-918
44. Gallopin T, Luppi PH, Cauli B, Urade Y, Rossier J, Hayaishi O, Lambolez B, Fort P (2005) The endogenous somnogen adenosine excites a subset of sleep-promoting neurons via A2A receptors in the ventrolateral preoptic nucleus. Neuroscience 134:1377-1390