Metabolic regulatory and anti-oxidative effects of modified bushen huoxue decoction on experimental rabbit model of osteoarthritis

Chinese Journal of Integrative Medicine

Volumn 19, Issue 6, 2013, Pages 459-463

  Liu, Wei ^a   Wu, Yuan Hao ^b   Liu, Xiao Ya ^a   Xue, Bin ^b   Shen, Wen ^b   Yang, Kuo ^b  

^a FIRST TEACHING HOSPITAL OF TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

hydroxyproline; Kidney reinforcing and blood activating; malonaldehyde; nitric oxide; osteoarthritis; superoxide dismutase

Indexed keywords

BUSHEN HUOXUE DECOCTION; CHINESE DRUG; GLUCOSAMINE SULFATE; HYDROXYPROLINE; MALONALDEHYDE; NITRIC OXIDE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANGELICA SINENSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CARTHAMUS; CARTILAGE; CHINESE MEDICINE; CISTANCHE; CONTROLLED STUDY; CUSCUTA; DOSE RESPONSE; ENZYME ACTIVITY; EUCOMMIACEAE; EXPERIMENTAL RABBIT; HISTOPATHOLOGY; HYDROXYPROLINE URINE LEVEL; KNEE; KNEE OSTEOARTHRITIS; MALE; METABOLIC REGULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN URINE LEVEL; REHMANNIA; SYNOVIUM; TISSUE HOMOGENATE;

ANIMALS; ANTIOXIDANTS; CARTILAGE, ARTICULAR; DISEASE MODELS, ANIMAL; DRUGS, CHINESE HERBAL; HYDROXYPROLINE; MALE; MALONDIALDEHYDE; NITRIC OXIDE; OSTEOARTHRITIS; RABBITS; SUPEROXIDE DISMUTASE; SYNOVIAL MEMBRANE;

EID: 84879650299     PISSN: 16720415     EISSN: 19930402     Source Type: Journal    
DOI: 10.1007/s11655-011-0727-x     Document Type: Article

References (12)

1. Special Committee of Rheumatology, Chinese Medical Association. Guideline for the diagnosis and treatment of osteoarthritis. Chin J Rheumatol (Chin) 2010;14:416-419.
2. Robert M, Ashok R, Steven B. The role of nitric oxide in inflammation and immunity. Arthritis Rheum 1998;41:1141.
3. Ozkan FU, Ozkan K, Ramadan S, Guven Z. Chondroprotective effect of N-acetylglucosamine and hyaluronate in early stages of osteoarthritis - an experimental study in rabbits. Bull NYU Hosp Jt Dis 2009;67:352-357.
4. Hotta H, Yamada H, Takaishi H, Abe T, Morioka H, Kikuchi T, et al. Type II collagen synthesis in the articular cartilage of a rabbit model of osteoarthritis: expression of type II collagen C-propeptide and mRNA especially during early-stage osteoarthritis. J Orthop Sci 2005;10:595-607
5. Mankin HJ, Dorfman H, Lippiello L, Zarins A. Biochemical and metabolic abnormalities in articular cartilage from osteoarthritic human hips. II. Correlation of morphology with biochemical and metabolic data. J Bone Joint Surg Am 1971;53: 523-537.
6. Mankin JH, Mow VC, Buckwalter JA. Form and function of articular cartilage. In: Simon SR, ed. Orthopaedic basic science. Rosemont: American Academy of Orthopeadic Surgeons; 1994:1-44.
7. Ostergaard K, Andersen CB, Petersen J, Bendtzen K, Salter DM. Validity of histopathological grading of articular cartilage from osteoarthritic knee joint. Ann Rheum Dis 1999;58:208-213.
8. Liu W, ed. Rheumatology diseases of integrative medicine. 1st ed. Wuhan: Huazhong University Press; 2009:145-147, 387-390.
9. Mazzi G, Fioravanzo F, Burti E. New marker of bone resorption: hydroxyproline-containing peptide. High-performance liquid chromatographic assay without hydrolysis as an alternative to hydroxyproline determination: a preliminary report. J Chromatogr B Biomed Appl 1996;678:165-172.
10. Hashimoto S, Takahashi K, Amiel D, Coutts RD, Lotz M. Chondrocyte apoptosis and nitric oxide production during experimentally induced osteoarthritis. Arthritis Rheum 1998; 41:1266-1274.
11. Blanco FJ, Guitian R, Vazquez-Martul E, de Toro FJ, Galdo F. Osteoarthritis chondrocytes die by apoptosis. A possible pathway for osteoarthritis pathology. Arthritis Rheum 1998;41:284-289.
12. Liu XX, Li XH, Zhou JT. Experimental study on replicating knee osteoarthritis by modified Hulth's modeling method. Chin J Integr Tradit West Med (Chin) 2005;25:1104-1108.