Type II collagen synthesis in the articular cartilage of a rabbit model of osteoarthritis: Expression of type II collagen C-propeptide and mRNA especially during early-stage osteoarthritis

Journal of Orthopaedic Science

Volumn 10, Issue 6, 2005, Pages 595-607

  Hotta, Hiraku ^a,b,d   Yamada, Harumoto ^c   Takaishi, Hironari ^a   Abe, Tomoyuki ^c   Morioka, Hideo ^a   Kikuchi, Toshiyuki ^b   Fujikawa, Kyosuke ^b   Toyama, Yoshiaki ^a  

^a KEIO UNIVERSITY   (Japan)

^b NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^c FUJITA HEALTH UNIVERSITY   (Japan)

^d TOKYO DENTAL COLLEGE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 2; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CARTILAGE DEGENERATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; GENE EXPRESSION; HISTOLOGY; IMMUNOHISTOCHEMISTRY; IMMUNOHISTOLOGY; IN SITU HYBRIDIZATION; MENISCECTOMY; NONHUMAN; OSTEOARTHRITIS; PROTEIN EXPRESSION; RABBIT; SCORING SYSTEM; STAINING;

EID: 28244497745     PISSN: 09492658     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00776-005-0947-z     Document Type: Article

References (23)

1. H Nakajima T Goto O Horikawa T Kikuchi M Shinmei 1998 Localization of carboxy-terminal type II procollagen peptide (pCOL-II-C) and type II collagen in the repair tissue of full-thickness articular cartilage defect Connect Tissue Res 37 195 204
2. F Nelson L Dahlberg S Laverty A Reiner I Pidoux M Ionescu 1998 Evidence for altered synthesis of type II collagen in patients with osteoarthritis J Clin Invest 102 2115 25
3. AR Poole F Nelson A Hollander A Reiner I Pidoux M Ionescu 1995 Collagen II turnover in joint diseases Acta Orthop Scand 66 Suppl 266 88 91
4. M Shinmei Y Inamori Y Yoshihara T Kikuchi T Hayakawa 1992 The potential of cartilage markers in joint fluid for drug evaluation KE Kuettner R Schleyerbach JG Peyron VC Hascall Articular cartilage and osteoarthritis Raven New York 597 609
5. M Shinmei K Ito S Matsuyama Y Yoshihara K Matsuzawa 1993 Joint fluid carboxy-terminal type II procollagen peptide as a marker of cartilage collagen biosynthesis Osteoarthritis Cartilage 1 121 8
6. C Colombo M Butler E O'Byrne L Hickman D Swartzendruber M Selwyn 1983 A new model of osteoarthritis in rabbits. I. Development of knee joint pathology following lateral meniscectomy and section of the fubular collateral and sesamoid ligaments Arthritis Rheum 26 875 86
7. HU Choi LH Tang TL Johnson S Pal LC Rosenberg A Reiner 1983 Isolation and characterization of a 35,000 molecular weight subunit fetal cartilage matrix protein J Biol Chem 258 655 61
8. Y Okada M Shinmei O Tanaka K Naka A Kimura I Nakanishi 1992 Localization of matrix metalloproteinase 3 (stromelysin) in osteoarthritic cartilage and synovium Lab Invest 66 680 90
9. H Takaishi H Yamada Y Yabe 1997 Preferential expression of alternatively spliced transcript of type II procollagen in the rabbit notochordal remnant and developing fibrocartilages Biochim Biophys Acta 1350 253 8
10. H Takaishi O Nemoto M Shiota T Kikuchi H Yamada M Yamagishi 1997 Type-II collagen gene expression is transiently upregulated in experimentally induced degeneration of rabbit intervertebral disc J Orthop Res 15 528 38
11. H Nakajima M Shinmei K Ito S Matsuyama T Kikuchi H Honda 1997 Localization of carboxy-terminal type II procollagen peptide (pCOL-II-C) in diseased cartilage J Orthop Sci 2 229 38
12. LS Lohmander Y Yoshihara H Roos T Kobayashi H Yamada M Shinmei 1996 Procollagen II C-propeptide in joint fluid: changes in concentrations with age, time after knee injury and osteoarthritis J Rheumatol 23 1765 9
13. H Kobayashi T Saito T Koshino 2002 Immunolocalization of carboxy-terminal type II procollagen peptide in regenerated articular cartilage of osteoarthritic knees after reduction of mechanical stress Osteoarthritis Cartilage 10 870 8
14. T Aigner SI Vornehm G Zeiler J Dudhia K von der Mark MT Bayliss 1997 Suppression of cartilage matrix gene expression in upper zone chondrocytes of osteoarthritic cartilage Arthritis Rheum 40 562 9
15. T Aigner H Stoss G Weseloh G Zeiler K von der Mark 1992 Activation of collagen type II expression in osteoarthritic and rheumatoid cartilage Virchows Arch B Cell Pathol Mol Pathol 62 337 45
16. T Aigner W Bertling H Stoss G Weseloh K von der Mark 1993 Independent expression of fibril-forming collagens I, II, and III in chondrocytes of human osteoarthritic cartilage J Clin Invest 91 829 37
17. T Aigner U Dietz H Stoss K von der Mark 1995 Differential expression of collagen types I, II, and X in human osteophytes Lab Invest 73 236 43
18. JR Matyas LJ Sandell ME Adams 1997 Gene expression of type II collagens in chondro-osteophytes in experimental osteoarthritis Osteoarthritis Cartilage 5 99 105
19. D Pfander R Rahmanzadeh EE Scheller 1999 Presence and distribution of collagen II, collagen I, fibronectin, and tenascin in rabbit normal and osteoarthritic cartilage J Rheumatol 26 386 94
20. R Stoop PM van der Kraan P Buma AD Hollander AR Poole WB van den Berg 1999 Denaturation of type II collagen in articular cartilage in experimental murine arthritis: evidence for collagen degradation in both reversible and irreversible cartilage damage J Pathol 188 329 37
21. R Stoop PM van der Kraan P Buma AP Hollander RC Billinghurst AR Poole 1999 Type II collagen degradation in spontaneous osteoarthritis in C57B1/6 and BALB/c mice Arthritis Rheum 42 2381 9
22. R Stoop P Buma PM van der Kraan AP Hollander RC Billinghurst THM Meijers 2001 Type II collagen degradation in articular cartilage fibrillation after anterior cruciate ligament transection in rats Osteoarthritis Cartilage 9 308 15
23. K Nakata S Miyamoto S Bernier M Tanaka A Utani P Krebsbach 1996 The C-propeptide of type II procollagen binds to the enhancer region of the type II procollagen gene and regulates its transcription Ann NY Acad Sci 785 307 8