Catastrophic inflammatory death of monocytes and macrophages by overtaking of a critical dose of endocytosed synthetic amorphous silica nanoparticles/serum protein complexes

Nanomedicine

Volumn 8, Issue 7, 2013, Pages 1101-1126

  Fedeli, Chiara ^a   Selvestrel, Francesco ^a   Tavano, Regina ^a   Segat, Daniela ^a   Mancin, Fabrizio ^a   Papini, Emanuele ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

amorphous silica; cell death; fetal calf serum; inflammatory cytokines; macrophages; monocytes; mononuclear phagocyte system; nanoparticles; reticular endothelial system

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 6; NANOPARTICLE; PLASMA PROTEIN; SILICON DIOXIDE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL COMPARTMENTALIZATION; CELL DEATH; CELL SPECIFICITY; CELL VIABILITY; CONCENTRATION RESPONSE; CYTOKINE PRODUCTION; CYTOTOXICITY; ENDOCYTOSIS; FLUORESCENCE ACTIVATED CELL SORTING; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERNALIZATION; LYMPHOCYTE; MACROPHAGE; MEASUREMENT; MONOCYTE; PARTICLE SIZE; PHAGOCYTE; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION;

EID: 84879636011     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.12.136     Document Type: Article

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