The membrane expression of Neisseria meningitidis adhesin A (NadA) increases the proimmune effects of MenB OMVs on human macrophages, compared with NadA- OMVs, without further stimulating their proinflammatory activity on circulating monocytes

Journal of Leukocyte Biology

Volumn 86, Issue 1, 2009, Pages 143-153

  Tavano, Regina ^a   Franzoso, Susanna ^a   Cecchini, Paola ^a   Cartocci, Elena ^b   Oriente, Francesca ^b   Aricò, Beatrice ^b   Papini, Emanuele ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b NOVARTIS VACCINES AND DIAGNOSTICS   (Italy)

Author keywords

Cell activation; Chemokines; Cytokines; Inflammation

Indexed keywords

ADHESIN; B7 ANTIGEN; BACTERIAL PROTEIN; CD86 ANTIGEN; HLA DR ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MEMBRANE PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; NEISSERIA MENINGITIDIS ADHESIN A; PROTEIN P40; PROTEIN P70; RANTES; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CHEMOKINE; CYTOKINE; LYASE; MEMBRANE ANTIGEN; NADA PROTEIN, NEISSERIA MENINGITIDIS;

ANTIGEN PRESENTATION; ARTICLE; BACTERIAL STRAIN; CELL STIMULATION; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVITY; ESCHERICHIA COLI; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LYMPHOCYTE; MACROPHAGE; MEMBRANE VESICLE; MONOCYTE; NEISSERIA MENINGITIDIS; OUTER MEMBRANE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; CELL CULTURE; CELL MEMBRANE; CHEMISTRY; ENZYMOLOGY; IMMUNOLOGY; MICROBIOLOGY; SECRETION;

ESCHERICHIA COLI; NEISSERIA MENINGITIDIS; OAT MOSAIC VIRUS;

ADHESINS, BACTERIAL; ANTIGENS, SURFACE; CELL MEMBRANE; CELLS, CULTURED; CHEMOKINES; CYTOKINES; HUMANS; MACROPHAGES; MONOCYTES; NEISSERIA MENINGITIDIS; OXO-ACID-LYASES;

EID: 68849122860     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0109030     Document Type: Article

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