Opportunities and limitations of intrinsic functional connectivity MRI

Nature Neuroscience

Volumn 16, Issue 7, 2013, Pages 832-837

  Buckner, Randy L ^a,b   Krienen, Fenna M ^a,b   Yeo, B T Thomas ^c  

^a HARVARD UNIVERSITY   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c DUKE NUS MEDICAL SCHOOL   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ASSOCIATION CORTEX; CORTICAL SYNCHRONIZATION; FUNCTIONAL CONNECTIVITY MAGNETIC RESONANCE IMAGING; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; HEAD MOVEMENT; HUMAN; INSULA; LIMBIC SYSTEM; MENTAL PERFORMANCE; NONHUMAN; PRIORITY JOURNAL; REVIEW; STRIATE CORTEX;

BRAIN; BRAIN MAPPING; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; NEURAL PATHWAYS;

EID: 84879628020     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/nn.3423     Document Type: Review

References (58)

1. Ogawa, S. et al. Functional brain mapping by blood oxygenation level-dependent contrast magnetic resonance imaging: a comparison of signal characteristics with a biophysical model. Biophys. J. 64, 803-812 (1993).
2. Biswal, B., Yetkin, F.Z., Haughton, V.M. & Hyde, J.S. Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. Magn. Reson. Med. 34, 537-541 (1995).
3. Greicius, M.D., Krasnow, B., Reiss, A.L. & Menon, V. Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. Proc. Natl. Acad. Sci. USA 100, 253-258 (2003).
4. Fox, M.D., Corbetta, M., Snyder, A.Z., Vincent, J.L. & Raichle, M.E. Spontaneous neuronal activity distinguishes human dorsal and ventral attention systems. Proc. Natl. Acad. Sci. USA 103, 10046-10051 (2006).
5. De Luca, M., Beckmann, C.F., De Stefano, N., Matthews, P.M. & Smith, S.M. fMRI resting state networks define distinct modes of long-distance interactions in the human brain. Neuroimage 29, 1359-1367 (2006).
6. Damoiseaux, J.S. et al. Consistent resting-state networks across healthy subjects. Proc. Natl. Acad. Sci. USA 103, 13848-13853 (2006).
7. Seeley, W.W. et al. Dissociable intrinsic connectivity networks for salience processing and executive control. J. Neurosci. 27, 2349-2356 (2007).
8. Margulies, D.S. et al. Mapping the functional connectivity of anterior cingulate cortex. Neuroimage 37, 579-588 (2007).
9. Dosenbach, N.U.F. et al. Distinct brain networks for adaptive and stable task control in humans. Proc. Natl. Acad. Sci. USA 104, 11073-11078 (2007).
10. Greicius, M. Resting-state functional connectivity in neuropsychiatric disorders. Curr. Opin. Neurol. 21, 424-430 (2008).
11. Zhang, D. & Raichle, M.E. Disease and the brain's dark energy. Nat. Rev. Neurol. 6, 15-28 (2010).
12. Buckner, R.L., Krienen, F.M., Castellanos, A., Diaz, J.C. & Yeo, B.T.T. The organization of the human cerebellum estimated by intrinsic functional connectivity. J. Neurophysiol. 106, 2322-2345 (2011).
13. Lu, J. et al. Focal pontine lesions provide evidence that intrinsic functional connectivity reflects polysynaptic anatomical pathways. J. Neurosci. 31, 15065-15071 (2011).
14. Johnston, J.M. et al. Loss of resting interhemispheric functional connectivity after complete section of the corpus callosum. J. Neurosci. 28, 6453-6458 (2008).
15. Damoiseaux, J.S. & Greicius, M.D. Greater than the sum of its parts: a review of studies combining structural connectivity and resting-state functional connectivity. Brain Struct. Funct. 213, 525-533 (2009).
16. Greicius, M.D., Supekar, K., Menon, V. & Dougherty, R.F. Resting-state functional connectivity reflects structural connectivity in the default mode network. Cereb. Cortex 19, 72-78 (2009).
17. Honey, C.J. et al. Predicting human resting-state functional connectivity from structural connectivity. Proc. Natl. Acad. Sci. USA 106, 2035-2040 (2009).
18. Vincent, J.L. et al. Intrinsic functional architecture in the anaesthetized monkey brain. Nature 447, 83-86 (2007).
19. Margulies, D.S. et al. Precuneus shares intrinsic functional architecture in humans and monkeys. Proc. Natl. Acad. Sci. USA 106, 20069-20074 (2009).
20. Mars, R.B. et al. Diffusion-weighted imaging tractography-based parcellation of the human parietal cortex and comparison with human and macaque resting-state functional connectivity. J. Neurosci. 31, 4087-4100 (2011).
21. Hill, J. et al. Similar patterns of cortical expansion during human development and evolution. Proc. Natl. Acad. Sci. USA 107, 13135-13140 (2010).
22. Tyszka, J.M., Kennedy, D.P., Adolphs, R. & Paul, L.K. Intact bilateral resting-state networks in the absence of the corpus callosum. J. Neurosci. 31, 15154-15162 (2011).
23. Shirer, W.R., Ryali, S., Rykhlevskaia, E., Menon, V. & Greicius, M.D. Decoding subject-driven cognitive states with whole-brain connectivity patterns. Cereb. Cortex 22, 158-165 (2012).
24. Lewis, C.M., Baldassarre, A., Committeri, G., Romani, G.L. & Corbetta, M. Learning sculpts the spontaneous activity of the resting human brain. Proc. Natl. Acad. Sci. USA 106, 17558-17563 (2009).
25. Hutchison, R.M., Womelsdorf, T., Gati, J.S., Everling, S. & Menon, R.S. Resting-state networks show dynamic functional connectivity in awake humans and anesthetized macaques. Hum. Brain Mapp. doi:dx10.1002/hbm.22058 (2012).
26. Handwerker, D.A., Gonzalez-Castillo, J., D'Esposito, M. & Bandettini, P.A. The continuing challenge of understanding and modeling hemodynamic variation in fMRI. Neuroimage 62, 1017-1023 (2012).
27. Van Dijk, K.R.A., Sabuncu, M.R. & Buckner, R.L. The influence of head motion on intrinsic functional connectivity MRI. Neuroimage 59, 431-438 (2012).
28. Power, J.D., Barnes, K.A., Snyder, A.Z., Schlaggar, B.L. & Petersen, S.E. Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion. Neuroimage 59, 2142-2154 (2012).
29. Birn, R.M., Smith, M.A., Jones, T.B. & Bandettini, P.A. The respiration response function: the temporal dynamics of fMRI signal fluctuations related to changes in respiration. Neuroimage 40, 644-654 (2008).
30. Deco, G. & Corbetta, M. The dynamical balance of the brain at rest. Neuroscientist 17, 107-123 (2011).
31. Andrews-Hanna, J.R. The brain's default network and its adaptive role in internal mentation. Neuroscientist 18, 251-270 (2012).
32. Spreng, R.N., Mar, R.A. & Kim, A.S.N. The common neural basis of autobiographical memory, prospection, navigation, theory of mind and the default mode: a quantitative meta-analysis. J. Cogn. Neurosci. 21, 489-510 (2009).
33. Smith, S.M. et al. Correspondence of the brain's functional architecture during activation and rest. Proc. Natl. Acad. Sci. USA 106, 13040-13045 (2009).
34. Bleuler, E. Dementia Praecox or the Group of Schizophrenias (ed. Zinkin, J.) (International Universities Press; New York, 1950).
35. Nolen-Hoeksma, S. The role of rumination in depressive disorders and mixed anxiety/depressive symptoms. J. Abnorm. Psychol. 109, 504-511 (2000).
36. Cohen, A.L. et al. Defining functional areas in individual human brains using resting functional connectivity MRI. Neuroimage 41, 45-57 (2008).
37. Yeo, B.T.T. et al. The organization of human cerebral cortex estimated by intrinsic functional connectivity. J. Neurophysiol. 106, 1125-1165 (2011).
38. Power, J.D. et al. Functional network organization of the human brain. Neuron 72, 665-678 (2011).
39. Kaas, J.H. The organization of neocortex in mammals: implications for theories of brain function. Annu. Rev. Psychol. 38, 129-151 (1987).
40. Wig, G.S., Schlaggar, B.L. & Petersen, S.E. Concepts and principles in the analysis of brain networks. Ann. NY Acad. Sci. 1224, 126-146 (2011).
41. Maunsell, J.H.R. & Van Essen, D.C. The connections of the middle temporal visual area (MT) and their relationship to a cortical hierarchy in the macaque monkey. J. Neurosci. 3, 2563-2586 (1983).
42. Passingham, R.E., Stephan, K.E. & Kötter, R. The anatomical basis of functional localization in the cortex. Nat. Rev. Neurosci. 3, 606-616 (2002).
43. Rosa, M.G.P. & Tweedale, R. Brain maps, great and small: lessons from comparative studies of primate visual cortical organization. Phil. Trans. R. Soc. Lond. B. Biol. Sci. 360, 665-691 (2005).
44. Rakic, P. Specification of cerebral cortical areas. Science 241, 170-176 (1988).
45. Mueller, S. et al. Individual variability in functional connectivity architecture of the human brain. Neuron 77, 586-595 (2013).
46. Goldman-Rakic, P.S. Topography of cognition: parallel distributed networks in primate association cortex. Annu. Rev. Neurosci. 11, 137-156 (1988).
47. Manni, E. & Petrosini, L. A century of cerebellar somatotopy: a debated representation. Nat. Rev. Neurosci. 5, 241-249 (2004).
48. Strick, P.L., Dum, R.P. & Fiez, J.A. Cerebellum and nonmotor function. Annu. Rev. Neurosci. 32, 413-434 (2009).
49. Habas, C. et al. Distinct cerebellar contributions to intrinsic connectivity networks. J. Neurosci. 29, 8586-8594 (2009).
50. O'Reilly, J.X., Beckmann, C.F., Tomassini, V., Ramnani, N. & Johansen-Berg, H. Distinct and overlapping functional zones in the cerebellum defined by resting state functional connectivity. Cereb. Cortex 20, 953-965 (2010).
51. Mesulam, M. The evolving landscape of human cortical connectivity: facts and inferences. Neuroimage 62, 2182-2189 (2012).
52. Fransson, P. Spontaneous low-frequency bold signal fluctuations: an fMRI investigation of the resting-state default mode of brain function hypothesis. Hum. Brain Mapp. 26, 15-29 (2005).
53. Fox, M.D. et al. The human brain is intrinsically organized into dynamic, anticorrelated functional networks. Proc. Natl. Acad. Sci. USA 102, 9673-9678 (2005).
54. Whitfield-Gabrieli, S. & Ford, J.M. Default mode network activity and connectivity in psychopathology. Annu. Rev. Clin. Psychol. 8, 49-76 (2012).
55. Murphy, K., Birn, R., Handwerker, D., Jones, T.B. & Bandettini, P.A. The impact of global signal regression on resting state correlations: are anti-correlated networks introduced? Neuroimage 44, 893-905 (2009).
56. Chai, X.J., Castañón, A.N., Öngür, D. & Whitfield-Gabrieli, S. Anticorrelations in resting state networks without global signal regression. Neuroimage 59, 1420-1428 (2012).
57. He, B.J., Snyder, A.Z., Zempel, J.M., Smyth, M.D. & Raichle, M.E. Electrophysiological correlates of the brain's intrinsic large-scale functional architecture. Proc. Natl. Acad. Sci. USA 105, 16039-16044 (2008).
58. Wang, L., Saalmann, Y.B., Pinsk, M.A., Arcaro, M.J. & Kastner, S. Electrophysiological low-frequency coherence and cross-frequency coupling contribute to BOLD connectivity. Neuron 76, 1010-1020 (2012).