Reversible and tissue-specific activation of MAP kinase signaling by tamoxifen in brafV637ERT2 mice

Genesis

Volumn 51, Issue 6, 2013, Pages 448-455

  Ortiz, Oskar ^a   Wurst, Wolfgang ^a,b,c,d   Kühn, Ralf ^a,b  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^d MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

Author keywords

Braf; Cre loxP; Estrogen receptor; MAPK; Rosa26; Tamoxifen; Transgenic mice

Indexed keywords

B RAF KINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; TAMOXIFEN; BRAF PROTEIN, MOUSE; ESTROGEN RECEPTOR; HYBRID PROTEIN;

ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ANALYSIS; EXPRESSION VECTOR; HETEROZYGOTE; HOMOZYGOTE; IMMUNOFLUORESCENCE; IN VIVO STUDY; KIDNEY; KNOCKOUT GENE; LIVER; LOSS OF FUNCTION MUTATION; MOUSE; NONHUMAN; NUCLEAR EXPORT SIGNAL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION; ANIMAL; ANTIBODY SPECIFICITY; CELL CULTURE; DRUG EFFECTS; EMBRYOLOGY; GENETIC RECOMBINATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; SPINAL CORD; TRANSCRIPTION INITIATION; TRANSGENIC MOUSE;

MUS; MUS MUSCULUS;

ANIMALS; BRAIN; CELLS, CULTURED; KIDNEY; LIVER; MAP KINASE SIGNALING SYSTEM; MICE; MICE, TRANSGENIC; ORGAN SPECIFICITY; PROTO-ONCOGENE PROTEINS B-RAF; RECEPTORS, ESTROGEN; RECOMBINANT FUSION PROTEINS; RECOMBINATION, GENETIC; SPINAL CORD; TAMOXIFEN; TRANSCRIPTIONAL ACTIVATION;

EID: 84879605796     PISSN: 1526954X     EISSN: 1526968X     Source Type: Journal    
DOI: 10.1002/dvg.22386     Document Type: Article

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