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Volumn 15, Issue 2, 2013, Pages 95-101

Sympathetic hyperactivity in chronic kidney disease: Pathophysiology and (New) treatment options

Author keywords

Chronic kidney disease; CKD; Hypertension; Renal denervation; Renin angiotensin system; Sympathetic hyperactivity; Sympathetic nervous system

Indexed keywords

ARTICLE; CARDIOVASCULAR RISK; CHRONIC KIDNEY DISEASE; DISEASE COURSE; EFFERENT NERVE; GLOMERULUS FILTRATION RATE; HUMAN; HYPERACTIVITY; KIDNEY DENERVATION; KIDNEY FUNCTION; KIDNEY ISCHEMIA; MORBIDITY; MORTALITY; PATHOPHYSIOLOGY; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SENSORY NERVE; SYMPATHETIC TONE;

EID: 84879602938     PISSN: 15226417     EISSN: 15343111     Source Type: Journal    
DOI: 10.1007/s11906-013-0328-5     Document Type: Article
Times cited : (43)

References (57)
  • 1
    • 77953291706 scopus 로고    scopus 로고
    • Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: A collaborative meta-analysis
    • 20483451 10.1016/S0140-6736(10)60674-5
    • Matsushita K, van der Velde M, Astor BC, et al. Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis. Lancet. 2010;375:2073-81.
    • (2010) Lancet , vol.375 , pp. 2073-2081
    • Matsushita, K.1    Van Der Velde, M.2    Astor, B.C.3
  • 2
    • 4644221457 scopus 로고    scopus 로고
    • Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
    • 15385656 10.1056/NEJMoa041031 1:CAS:528:DC%2BD2cXnvFSgtr8%3D
    • Go AS, Chertow GM, Fan D, et al. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med. 2004;351:1296-305.
    • (2004) N Engl J Med , vol.351 , pp. 1296-1305
    • Go, A.S.1    Chertow, G.M.2    Fan, D.3
  • 3
    • 84868588459 scopus 로고    scopus 로고
    • Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without hypertension: A meta-analysis
    • 23013600 10.1016/S0140-6736(12)61272-0
    • Mahmoodi BK, Matsushita K, Woodward M, et al. Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without hypertension: a meta-analysis. Lancet. 2012;380:1649-61.
    • (2012) Lancet , vol.380 , pp. 1649-1661
    • Mahmoodi, B.K.1    Matsushita, K.2    Woodward, M.3
  • 4
    • 0037133633 scopus 로고    scopus 로고
    • Plasma norepinephrine predicts survival and incident cardiovascular events in patients with end-stage renal disease
    • 11901048 10.1161/hc1102.105261 1:CAS:528:DC%2BD38XjtFalsL8%3D
    • Zoccali C, Mallamaci F, Parlongo S, et al. Plasma norepinephrine predicts survival and incident cardiovascular events in patients with end-stage renal disease. Circulation. 2002;105:1354-9.
    • (2002) Circulation , vol.105 , pp. 1354-1359
    • Zoccali, C.1    Mallamaci, F.2    Parlongo, S.3
  • 5
    • 67649402292 scopus 로고    scopus 로고
    • Sympathetic hyperactivity and clinical outcome in chronic kidney disease patients during standard treatment
    • 19384838
    • Penne EL, Neumann J, Klein IH, et al. Sympathetic hyperactivity and clinical outcome in chronic kidney disease patients during standard treatment. J Nephrol. 2009;22:208-15.
    • (2009) J Nephrol , vol.22 , pp. 208-215
    • Penne, E.L.1    Neumann, J.2    Klein, I.H.3
  • 6
    • 0025026511 scopus 로고
    • Overflow of catecholamine neurotransmitters to the circulation: Source, fate, and functions
    • 1977182 1:CAS:528:DyaK3MXkvVGntbc%3D
    • Esler M, Jennings G, Lambert G, et al. Overflow of catecholamine neurotransmitters to the circulation: source, fate, and functions. Physiol Rev. 1990;70:963-85.
    • (1990) Physiol Rev , vol.70 , pp. 963-985
    • Esler, M.1    Jennings, G.2    Lambert, G.3
  • 7
    • 77951069805 scopus 로고    scopus 로고
    • Sympathetic nervous system overactivity and its role in the development of cardiovascular disease
    • 20393193 10.1152/physrev.00007.2009 1:CAS:528:DC%2BC3cXht1erurnN
    • Malpas SC. Sympathetic nervous system overactivity and its role in the development of cardiovascular disease. Physiol Rev. 2010;90:513-57.
    • (2010) Physiol Rev , vol.90 , pp. 513-557
    • Malpas, S.C.1
  • 8
    • 0027164718 scopus 로고
    • Long-term variability and reproducibility of resting human muscle nerve sympathetic activity at rest, as reassessed after a decade
    • 8400820 10.1007/BF01826234 1:STN:280:DyaK2c%2Fgtl2lsA%3D%3D
    • Fagius J, Wallin BG. Long-term variability and reproducibility of resting human muscle nerve sympathetic activity at rest, as reassessed after a decade. Clin Auton Res. 1993;3:201-5.
    • (1993) Clin Auton Res , vol.3 , pp. 201-205
    • Fagius, J.1    Wallin, B.G.2
  • 9
    • 77957220275 scopus 로고    scopus 로고
    • Sympathetic activity in chronic kidney disease patients is related to left ventricular mass despite antihypertensive treatment
    • 20360012 10.1093/ndt/gfq175
    • Siddiqi L, Prakken NH, Velthuis BK, et al. Sympathetic activity in chronic kidney disease patients is related to left ventricular mass despite antihypertensive treatment. Nephrol Dial Transplant. 2010;25:3272-7.
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 3272-3277
    • Siddiqi, L.1    Prakken, N.H.2    Velthuis, B.K.3
  • 10
    • 84879603536 scopus 로고    scopus 로고
    • Aliskiren reduces sympathetic nerve activity and blood pressure in chronic kidney disease patients
    • Siddiqi L, Oey PL, Blankestijn PJ. Aliskiren reduces sympathetic nerve activity and blood pressure in chronic kidney disease patients. Nephrol Dial Transplant 2011;11:2176-80.
    • (2011) Nephrol Dial Transplant , vol.11 , pp. 2176-2180
    • Siddiqi, L.1    Oey, P.L.2    Blankestijn, P.J.3
  • 11
    • 0033614449 scopus 로고    scopus 로고
    • Reduction of sympathetic hyperactivity by enalapril in patients with chronic renal failure
    • 10219067 10.1056/NEJM199904293401704 1:CAS:528:DyaK1MXjtVWqtL4%3D
    • Ligtenberg G, Blankestijn PJ, Oey PL, et al. Reduction of sympathetic hyperactivity by enalapril in patients with chronic renal failure. N Engl J Med. 1999;340:1321-8.
    • (1999) N Engl J Med , vol.340 , pp. 1321-1328
    • Ligtenberg, G.1    Blankestijn, P.J.2    Oey, P.L.3
  • 12
    • 0034758803 scopus 로고    scopus 로고
    • Sympathetic activity is increased in polycystic kidney disaese and is associated with hypertension
    • 11675419 1:CAS:528:DC%2BD3MXotl2ls74%3D
    • Klein IHHT, Ligtenberg G, Oey PL, et al. Sympathetic activity is increased in polycystic kidney disaese and is associated with hypertension. J Am Soc Nephrol. 2001;12:2427-33.
    • (2001) J Am Soc Nephrol , vol.12 , pp. 2427-2433
    • Klein, I.1    Ligtenberg, G.2    Oey, P.L.3
  • 13
    • 0037304676 scopus 로고    scopus 로고
    • Enalapril and losartan reduce sympathetic hyperactivity in patients with chronic renal failure
    • 12538743 10.1097/01.ASN.0000045049.72965.B7 1:CAS:528: DC%2BD3sXivVygsw%3D%3D
    • Klein IH, Ligtenberg G, Oey PL, et al. Enalapril and losartan reduce sympathetic hyperactivity in patients with chronic renal failure. J Am Soc Nephrol. 2003;14:425-30.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 425-430
    • Klein, I.H.1    Ligtenberg, G.2    Oey, P.L.3
  • 14
    • 16644394816 scopus 로고    scopus 로고
    • Moxonidine normalizes sympathetic hyperactivity in patients with eprosartan-treated chronic renal failure
    • 15504943 10.1097/01.ASN.0000143471.10750.8C 1:CAS:528: DC%2BD2cXos1Gjur4%3D
    • Neumann J, Ligtenberg G, Oey L, et al. Moxonidine normalizes sympathetic hyperactivity in patients with eprosartan-treated chronic renal failure. J Am Soc Nephrol. 2004;15:2902-7.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2902-2907
    • Neumann, J.1    Ligtenberg, G.2    Oey, L.3
  • 15
    • 0026684060 scopus 로고
    • Simultaneous measurements of cardiac noradrenaline spillover and sympathetic outflow to skeletal muscle in humans
    • 1464839 1:CAS:528:DyaK38Xkt1Sqsb8%3D
    • Wallin BG, Esler M, Dorward P, et al. Simultaneous measurements of cardiac noradrenaline spillover and sympathetic outflow to skeletal muscle in humans. J Physiol. 1992;453:45-58.
    • (1992) J Physiol , vol.453 , pp. 45-58
    • Wallin, B.G.1    Esler, M.2    Dorward, P.3
  • 16
    • 0029872269 scopus 로고    scopus 로고
    • Renal noradrenaline spillover correlates with muscle sympathetic activity in humans
    • 8815219 1:CAS:528:DyaK28XitVemur4%3D
    • Wallin BG, Thompson JM, Jennings GL, Esler MD. Renal noradrenaline spillover correlates with muscle sympathetic activity in humans. J Physiol. 1996;491(Pt 3):881-7.
    • (1996) J Physiol , vol.491 , Issue.PART 3 , pp. 881-887
    • Wallin, B.G.1    Thompson, J.M.2    Jennings, G.L.3    Esler, M.D.4
  • 17
    • 0026719883 scopus 로고
    • Interactions between ANG II, sympathetic nervous system, and baroreceptor reflexes in regulation of blood pressure
    • 1616014 1:CAS:528:DyaK38XltVCgt78%3D
    • Reid IA. Interactions between ANG II, sympathetic nervous system, and baroreceptor reflexes in regulation of blood pressure. Am J Physiol. 1992;262:E763-78.
    • (1992) Am J Physiol , vol.262
    • Reid, I.A.1
  • 18
    • 0031864055 scopus 로고    scopus 로고
    • A limited renal injury may cause a permanent form of neurogenic hypertension
    • 9657632 10.1016/S0895-7061(98)00030-2 1:CAS:528:DyaK1cXktlers78%3D
    • Ye S, Gamburd M, Mozayeni P, et al. A limited renal injury may cause a permanent form of neurogenic hypertension. Am J Hypertens. 1998;11:723-8.
    • (1998) Am J Hypertens , vol.11 , pp. 723-728
    • Ye, S.1    Gamburd, M.2    Mozayeni, P.3
  • 19
    • 0028953330 scopus 로고
    • Renal afferent denervation prevents hypertension in rats with chronic renal failure
    • 7721447 10.1161/01.HYP.25.4.878 1:STN:280:DyaK2M3jvVSjsw%3D%3D
    • Campese VM, Kogosov E. Renal afferent denervation prevents hypertension in rats with chronic renal failure. Hypertension. 1995;25:878-82.
    • (1995) Hypertension , vol.25 , pp. 878-882
    • Campese, V.M.1    Kogosov, E.2
  • 20
    • 0028858468 scopus 로고
    • Renal afferent denervation prevents the progression of renal disease in the renal ablation model of chronic renal failure in the rat
    • 7485145 10.1016/0272-6386(95)90456-5 1:STN:280:DyaK28%2FlsV2isA%3D%3D
    • Campese VM, Kogosov E, Koss M. Renal afferent denervation prevents the progression of renal disease in the renal ablation model of chronic renal failure in the rat. Am J Kidney Dis. 1995;26:861-5.
    • (1995) Am J Kidney Dis , vol.26 , pp. 861-865
    • Campese, V.M.1    Kogosov, E.2    Koss, M.3
  • 21
    • 0028431868 scopus 로고
    • Altered norepinephrine turnover in the brain of rats with chronic renal failure
    • 7919142 1:CAS:528:DyaK2cXltVGqurY%3D
    • Bigazzi R, Kogosov E, Campese VM. Altered norepinephrine turnover in the brain of rats with chronic renal failure. J Am Soc Nephrol. 1994;4:1901-7.
    • (1994) J Am Soc Nephrol , vol.4 , pp. 1901-1907
    • Bigazzi, R.1    Kogosov, E.2    Campese, V.M.3
  • 22
    • 0021172352 scopus 로고
    • Intrarenal adenosine produces hypertension by activating the sympathetic nervous system via the renal nerves in the dog
    • 6397533 1:CAS:528:DyaL2cXmt1OqtLc%3D
    • Katholi RE, Whitlow PL, Hageman GR, Woods WT. Intrarenal adenosine produces hypertension by activating the sympathetic nervous system via the renal nerves in the dog. J Hypertens. 1984;2:349-59.
    • (1984) J Hypertens , vol.2 , pp. 349-359
    • Katholi, R.E.1    Whitlow, P.L.2    Hageman, G.R.3    Woods, W.T.4
  • 23
    • 1542349096 scopus 로고    scopus 로고
    • Sympathetic hyperactivity in chronic renal failure: A wake-up call
    • 14978154 10.1097/01.ASN.0000113320.57127.B9
    • Koomans HA, Blankestijn PJ, Joles JA. Sympathetic hyperactivity in chronic renal failure: a wake-up call. J Am Soc Nephrol. 2004;15:524-37.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 524-537
    • Koomans, H.A.1    Blankestijn, P.J.2    Joles, J.A.3
  • 24
    • 0027075024 scopus 로고
    • Sympathetic overactivity in patients with chronic renal failure
    • 1454086 10.1056/NEJM199212313272704
    • Converse Jr RL, Jacobsen TN, Toto RD, et al. Sympathetic overactivity in patients with chronic renal failure. N Engl J Med. 1992;327:1912-8.
    • (1992) N Engl J Med , vol.327 , pp. 1912-1918
    • Converse, Jr.R.L.1    Jacobsen, T.N.2    Toto, R.D.3
  • 25
    • 0037044429 scopus 로고    scopus 로고
    • Sympathetic nerve activity in end-stage renal disease
    • 12370222 10.1161/01.CIR.0000034043.16664.96
    • Hausberg M, Kosch M, Harmelink P, et al. Sympathetic nerve activity in end-stage renal disease. Circulation. 2002;106:1974-9.
    • (2002) Circulation , vol.106 , pp. 1974-1979
    • Hausberg, M.1    Kosch, M.2    Harmelink, P.3
  • 26
    • 0344236401 scopus 로고    scopus 로고
    • Sympathetic nerve activity is inappropriately increased in chronic renal disease
    • 14638922 10.1097/01.ASN.0000098687.01005.A5
    • Klein IH, Ligtenberg G, Neumann J, et al. Sympathetic nerve activity is inappropriately increased in chronic renal disease. J Am Soc Nephrol. 2003;14:3239-44.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 3239-3244
    • Klein, I.H.1    Ligtenberg, G.2    Neumann, J.3
  • 27
    • 79953177793 scopus 로고    scopus 로고
    • Early sympathetic activation in the initial clinical stages of chronic renal failure
    • 21300663 10.1161/HYPERTENSIONAHA.110.164780 1:CAS:528: DC%2BC3MXjt1GnsLc%3D
    • Grassi G, Quarti-Trevano F, Seravalle G, et al. Early sympathetic activation in the initial clinical stages of chronic renal failure. Hypertension. 2011;57:846-51.
    • (2011) Hypertension , vol.57 , pp. 846-851
    • Grassi, G.1    Quarti-Trevano, F.2    Seravalle, G.3
  • 28
    • 0031915176 scopus 로고    scopus 로고
    • Baroreflex control of sympathetic nerve activity in essential and secondary hypertension
    • 9449393 10.1161/01.HYP.31.1.68 1:STN:280:DyaK1c7gvFCntQ%3D%3D
    • Grassi G, Cattaneo BM, Seravalle G, et al. Baroreflex control of sympathetic nerve activity in essential and secondary hypertension. Hypertension. 1998;31:68-72.
    • (1998) Hypertension , vol.31 , pp. 68-72
    • Grassi, G.1    Cattaneo, B.M.2    Seravalle, G.3
  • 29
    • 0025222614 scopus 로고
    • Renal structure and hypertension in autosomal dominant polycystic kidney disease
    • 2074659 10.1038/ki.1990.330 1:STN:280:DyaK3M7mt12gsw%3D%3D
    • Gabow PA, Chapman AB, Johnson AM, et al. Renal structure and hypertension in autosomal dominant polycystic kidney disease. Kidney Int. 1990;38:1177-80.
    • (1990) Kidney Int , vol.38 , pp. 1177-1180
    • Gabow, P.A.1    Chapman, A.B.2    Johnson, A.M.3
  • 30
    • 0026017880 scopus 로고
    • Muscle sympathetic nerve activity in renovascular hypertension and primary aldosteronism
    • 1828457 10.1161/01.HYP.17.6.1057 1:STN:280:DyaK3M3lsl2ntw%3D%3D
    • Miyajima E, Yamada Y, Yoshida Y, et al. Muscle sympathetic nerve activity in renovascular hypertension and primary aldosteronism. Hypertension. 1991;17:1057-62.
    • (1991) Hypertension , vol.17 , pp. 1057-1062
    • Miyajima, E.1    Yamada, Y.2    Yoshida, Y.3
  • 31
    • 0033912730 scopus 로고    scopus 로고
    • Effects of low dose sympathetic inhibition on glomerulosclerosis and albuminuria in subtotally nephrectomized rats
    • 10906160 1:CAS:528:DC%2BD3cXlvVyhtrY%3D
    • Amann K, Rump LC, Simonaviciene A, et al. Effects of low dose sympathetic inhibition on glomerulosclerosis and albuminuria in subtotally nephrectomized rats. J Am Soc Nephrol. 2000;11:1469-78.
    • (2000) J Am Soc Nephrol , vol.11 , pp. 1469-1478
    • Amann, K.1    Rump, L.C.2    Simonaviciene, A.3
  • 32
    • 48149097894 scopus 로고    scopus 로고
    • Autonomic renal denervation ameliorates experimental glomerulonephritis
    • 18400940 10.1681/ASN.2007050552 1:CAS:528:DC%2BD1cXovFeks7k%3D
    • Veelken R, Vogel EM, Hilgers K, et al. Autonomic renal denervation ameliorates experimental glomerulonephritis. J Am Soc Nephrol. 2008;19:1371-8.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 1371-1378
    • Veelken, R.1    Vogel, E.M.2    Hilgers, K.3
  • 33
    • 0345059993 scopus 로고    scopus 로고
    • A nitric oxide-generating beta-blocking agent prevents renal injury in the rat remnant kidney model. Comparative study of two beta-blocking drugs, nipradilol and propranolol
    • 10.1159/000068529
    • Takamitsu Y, Nakanishi T, Nishihara F, et al. A nitric oxide-generating beta-blocking agent prevents renal injury in the rat remnant kidney model. Comparative study of two beta-blocking drugs, nipradilol and propranolol. Nephron Physiol. 2003;93:42-50.
    • (2003) Nephron Physiol , vol.93 , pp. 42-50
    • Takamitsu, Y.1    Nakanishi, T.2    Nishihara, F.3
  • 34
    • 0027258341 scopus 로고
    • Comparison between carvedilol and captopril in rats with partial ablation-induced chronic renal failure
    • 8102931 10.1111/j.1476-5381.1993.tb13610.x 1:CAS:528:DyaK3sXkvVGksLY%3D
    • Brooks DP, Short BG, Cyronak MJ, et al. Comparison between carvedilol and captopril in rats with partial ablation-induced chronic renal failure. Br J Pharmacol. 1993;109:581-6.
    • (1993) Br J Pharmacol , vol.109 , pp. 581-586
    • Brooks, D.P.1    Short, B.G.2    Cyronak, M.J.3
  • 35
    • 77956252045 scopus 로고    scopus 로고
    • Renal denervation reduces glomerular injury by suppressing NAD(P)H oxidase activity in Dahl salt-sensitive rats
    • 20299340 10.1093/ndt/gfq139 1:CAS:528:DC%2BC3cXhtV2rtrjL
    • Nagasu H, Satoh M, Kuwabara A, et al. Renal denervation reduces glomerular injury by suppressing NAD(P)H oxidase activity in Dahl salt-sensitive rats. Nephrol Dial Transplant. 2010;25:2889-98.
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 2889-2898
    • Nagasu, H.1    Satoh, M.2    Kuwabara, A.3
  • 36
    • 3142574854 scopus 로고    scopus 로고
    • Nitric oxide, oxidative stress, and progression of chronic renal failure
    • 15252775 10.1016/j.semnephrol.2004.04.007 1:CAS:528:DC%2BD2cXntVeksL0%3D
    • Modlinger PS, Wilcox CS, Aslam S. Nitric oxide, oxidative stress, and progression of chronic renal failure. Semin Nephrol. 2004;24:354-65.
    • (2004) Semin Nephrol , vol.24 , pp. 354-365
    • Modlinger, P.S.1    Wilcox, C.S.2    Aslam, S.3
  • 37
    • 0042733634 scopus 로고    scopus 로고
    • Moxonidine treatment of hypertensive patients with advanced renal failure
    • 12923404 10.1097/00004872-200309000-00021 1:CAS:528:DC%2BD3sXmtl2ksLY%3D
    • Vonend O, Marsalek P, Russ H, et al. Moxonidine treatment of hypertensive patients with advanced renal failure. J Hypertens. 2003;21:1709-17.
    • (2003) J Hypertens , vol.21 , pp. 1709-1717
    • Vonend, O.1    Marsalek, P.2    Russ, H.3
  • 38
    • 0021150852 scopus 로고
    • Sympathetic outflow to muscles during treatment of hypertension with metoprolol
    • 6378790 10.1161/01.HYP.6.4.557 1:STN:280:DyaL2c3mtlequw%3D%3D
    • Wallin BG, Sundlof G, Stromgren E, Aberg H. Sympathetic outflow to muscles during treatment of hypertension with metoprolol. Hypertension. 1984;6:557-62.
    • (1984) Hypertension , vol.6 , pp. 557-562
    • Wallin, B.G.1    Sundlof, G.2    Stromgren, E.3    Aberg, H.4
  • 39
    • 4644298714 scopus 로고    scopus 로고
    • Arterial pressure lowering effect of chronic atenolol therapy in hypertension and vasoconstrictor sympathetic drive
    • 15326085 10.1161/01.HYP.0000141411.94596.0f 1:CAS:528: DC%2BD2cXnslenu7Y%3D
    • Burns J, Mary DA, Mackintosh AF, et al. Arterial pressure lowering effect of chronic atenolol therapy in hypertension and vasoconstrictor sympathetic drive. Hypertension. 2004;44:454-8.
    • (2004) Hypertension , vol.44 , pp. 454-458
    • Burns, J.1    Mary, D.A.2    Mackintosh, A.F.3
  • 40
    • 33845267499 scopus 로고    scopus 로고
    • Beta blockers in the management of chronic kidney disease
    • 17021610 1:CAS:528:DC%2BD28Xht1Cls7nO
    • Bakris GL, Hart P, Ritz E. Beta blockers in the management of chronic kidney disease. Kidney Int. 2006;70:1905-13.
    • (2006) Kidney Int , vol.70 , pp. 1905-1913
    • Bakris, G.L.1    Hart, P.2    Ritz, E.3
  • 41
    • 0037335346 scopus 로고    scopus 로고
    • Short-versus long-term effects of different dihydropyridines on sympathetic and baroreflex function in hypertension
    • 12623959 10.1161/01.HYP.0000058003.27729.5A 1:CAS:528: DC%2BD3sXhsV2ksrY%3D
    • Grassi G, Seravalle G, Turri C, et al. Short-versus long-term effects of different dihydropyridines on sympathetic and baroreflex function in hypertension. Hypertension. 2003;41:558-62.
    • (2003) Hypertension , vol.41 , pp. 558-562
    • Grassi, G.1    Seravalle, G.2    Turri, C.3
  • 42
    • 80054106555 scopus 로고    scopus 로고
    • Atorvastatin reduces sympathetic activity in patients with chronic kidney disease
    • 21897294 10.1097/HJH.0b013e32834ae3c7 1:CAS:528:DC%2BC3MXht12rsLfO
    • Siddiqi L, Joles JA, Oey PL, Blankestijn PJ. Atorvastatin reduces sympathetic activity in patients with chronic kidney disease. J Hypertens. 2011;29:2176-80.
    • (2011) J Hypertens , vol.29 , pp. 2176-2180
    • Siddiqi, L.1    Joles, J.A.2    Oey, P.L.3    Blankestijn, P.J.4
  • 43
    • 65249137181 scopus 로고    scopus 로고
    • Differential effects of chlorthalidone versus spironolactone on muscle sympathetic nerve activity in hypertensive patients
    • 19158191 10.1210/jc.2008-2660 1:CAS:528:DC%2BD1MXksFaiurg%3D
    • Menon DV, Arbique D, Wang Z, et al. Differential effects of chlorthalidone versus spironolactone on muscle sympathetic nerve activity in hypertensive patients. J Clin Endocrinol Metab. 2009;94:1361-6.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 1361-1366
    • Menon, D.V.1    Arbique, D.2    Wang, Z.3
  • 44
    • 84864276593 scopus 로고    scopus 로고
    • Spironolactone prevents chlorthalidone-induced sympathetic activation and insulin resistance in hypertensive patients
    • 22733474 10.1161/HYPERTENSIONAHA.112.194787 1:CAS:528:DC%2BC38XhtVCrs7zM
    • Raheja P, Price A, Wang Z, et al. Spironolactone prevents chlorthalidone-induced sympathetic activation and insulin resistance in hypertensive patients. Hypertension. 2012;60:319-25.
    • (2012) Hypertension , vol.60 , pp. 319-325
    • Raheja, P.1    Price, A.2    Wang, Z.3
  • 45
    • 50349121171 scopus 로고
    • Hypertension and its surgical treatment by bilateral supradiaphragmatic splanchnicectomy
    • 18918421 10.1016/0002-9610(48)90284-0 1:STN:280:DyaH1c%2Fmt1Wlug%3D%3D
    • Peet MM. Hypertension and its surgical treatment by bilateral supradiaphragmatic splanchnicectomy. Am J Surg. 1948;75:48-68.
    • (1948) Am J Surg , vol.75 , pp. 48-68
    • Peet, M.M.1
  • 46
    • 64049084640 scopus 로고    scopus 로고
    • Catheter-based renal sympathetic denervation for resistant hypertension: A multicentre safety and proof-of-principle cohort study
    • 19332353 10.1016/S0140-6736(09)60566-3
    • Krum H, Schlaich M, Whitbourn R, et al. Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study. Lancet. 2009;373:1275-81.
    • (2009) Lancet , vol.373 , pp. 1275-1281
    • Krum, H.1    Schlaich, M.2    Whitbourn, R.3
  • 47
    • 78649876825 scopus 로고    scopus 로고
    • Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): A randomised controlled trial
    • 21093036 10.1016/S0140-6736(10)62039-9 The first randomized controlled trial investigating safety and efficacy of renal denervation as treatment of resistant hypertension
    • • Esler MD, Krum H, Sobotka PA, et al. Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): a randomised controlled trial. Lancet. 2010;376:1903-9. The first randomized controlled trial investigating safety and efficacy of renal denervation as treatment of resistant hypertension.
    • (2010) Lancet , vol.376 , pp. 1903-1909
    • Esler, M.D.1    Krum, H.2    Sobotka, P.A.3
  • 48
    • 79955477242 scopus 로고    scopus 로고
    • Catheter-based renal sympathetic denervation for resistant hypertension: Durability of blood pressure reduction out to 24 months
    • Symplicity HTN-1 Investigators 10.1161/HYPERTENSIONAHA.110.163014
    • Symplicity HTN-1 Investigators. Catheter-based renal sympathetic denervation for resistant hypertension: durability of blood pressure reduction out to 24 months. Hypertension. 2011;57:911-7.
    • (2011) Hypertension , vol.57 , pp. 911-917
  • 49
    • 69349085170 scopus 로고    scopus 로고
    • Renal sympathetic-nerve ablation for uncontrolled hypertension
    • 19710497 10.1056/NEJMc0904179 1:CAS:528:DC%2BD1MXhtVKhtbrL The first report investigating the effect of renal denervation on MSNA
    • • Schlaich MP, Sobotka PA, Krum H, et al. Renal sympathetic-nerve ablation for uncontrolled hypertension. N Engl J Med. 2009;361:932-4. The first report investigating the effect of renal denervation on MSNA.
    • (2009) N Engl J Med , vol.361 , pp. 932-934
    • Schlaich, M.P.1    Sobotka, P.A.2    Krum, H.3
  • 50
    • 84870245724 scopus 로고    scopus 로고
    • Catheter-based renal nerve ablation and centrally generated sympathetic activity in difficult-to-control hypertensive patients: Prospective case series
    • One of the first reports investigating the effect of renal denervation on MSNA
    • • Brinkmann J, Heusser K, Schmidt BM et al. Catheter-based renal nerve ablation and centrally generated sympathetic activity in difficult-to-control hypertensive patients: prospective case series. Hypertension 2012;11:1485-90. One of the first reports investigating the effect of renal denervation on MSNA.
    • (2012) Hypertension , vol.11 , pp. 1485-1490
    • Brinkmann, J.1    Heusser, K.2    Schmidt, B.M.3
  • 51
    • 84873058305 scopus 로고    scopus 로고
    • Substantial reduction in single sympathetic nerve firing after renal denervation in patients with resistant hypertension
    • One of the first reports investigating the effect of renal denervation on MSNA
    • • Hering D, Lambert EA, Marusic P et al. Substantial reduction in single sympathetic nerve firing after renal denervation in patients with resistant hypertension. Hypertension 2012;2:457-64. One of the first reports investigating the effect of renal denervation on MSNA.
    • (2012) Hypertension , vol.2 , pp. 457-464
    • Hering, D.1    Lambert, E.A.2    Marusic, P.3
  • 52
    • 84873058422 scopus 로고    scopus 로고
    • Catheter-based renal nerve ablation and centrally generated sympathetic activity in difficult-to-control hypertensive patients
    • Vink EE, Blankestijn PJ. Catheter-based renal nerve ablation and centrally generated sympathetic activity in difficult-to-control hypertensive patients. Hypertension 2012;61:e8.
    • (2012) Hypertension , vol.61
    • Vink, E.E.1    Blankestijn, P.J.2
  • 53
    • 84857773847 scopus 로고    scopus 로고
    • Renal sympathetic denervation reduces left ventricular hypertrophy and improves cardiac function in patients with resistant hypertension
    • 22381425 10.1016/j.jacc.2011.11.034 The first randomized controlled trial investigating the effect of renal denervation on left ventricular hypertrophy in patients with hypertension
    • • Brandt MC, Mahfoud F, Reda S, et al. Renal sympathetic denervation reduces left ventricular hypertrophy and improves cardiac function in patients with resistant hypertension. J Am Coll Cardiol. 2012;59:901-9. The first randomized controlled trial investigating the effect of renal denervation on left ventricular hypertrophy in patients with hypertension.
    • (2012) J Am Coll Cardiol , vol.59 , pp. 901-909
    • Brandt, M.C.1    Mahfoud, F.2    Reda, S.3
  • 54
    • 79955755012 scopus 로고    scopus 로고
    • Effect of renal sympathetic denervation on glucose metabolism in patients with resistant hypertension: A pilot study
    • 21518978 10.1161/CIRCULATIONAHA.110.991869 1:CAS:528:DC%2BC3MXlslynt74%3D
    • Mahfoud F, Schlaich M, Kindermann I, et al. Effect of renal sympathetic denervation on glucose metabolism in patients with resistant hypertension: a pilot study. Circulation. 2011;123:1940-6.
    • (2011) Circulation , vol.123 , pp. 1940-1946
    • Mahfoud, F.1    Schlaich, M.2    Kindermann, I.3
  • 55
    • 84863528992 scopus 로고    scopus 로고
    • Renal denervation in moderate to severe CKD
    • The first pilot study investigating safety and efficacy of renal denervation in CKD
    • • Hering D, Mahfoud F, Walton AS et al. Renal denervation in moderate to severe CKD. J Am Soc Nephrol 2012. The first pilot study investigating safety and efficacy of renal denervation in CKD.
    • (2012) J Am Soc Nephrol
    • Hering, D.1    Mahfoud, F.2    Walton, A.S.3
  • 56
    • 84859320826 scopus 로고    scopus 로고
    • Renal sympathetic nerve ablation for the treatment of difficult-to-control or refractory hypertension in a haemodialysis patient
    • 10.1093/ndt/gfs044
    • Di Danielle DN, De FM, Violo L, et al. Renal sympathetic nerve ablation for the treatment of difficult-to-control or refractory hypertension in a haemodialysis patient. Nephrol Dial Transplant. 2012;27:1689-90.
    • (2012) Nephrol Dial Transplant , vol.27 , pp. 1689-1690
    • Di Danielle, D.N.1    De, F.M.2    Violo, L.3
  • 57
    • 84868573128 scopus 로고    scopus 로고
    • Renal denervation in a hypertensive patient with end-stage renal disease and small arteries: A direction for future research
    • 10.1111/jch.12017
    • Ott C, Schmid A, Ditting T, et al. Renal denervation in a hypertensive patient with end-stage renal disease and small arteries: a direction for future research. J Clin Hypertens. 2012;14:799-801.
    • (2012) J Clin Hypertens , vol.14 , pp. 799-801
    • Ott, C.1    Schmid, A.2    Ditting, T.3


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