Differential anti-tumor activities of curcumin against Ras- and Src-activated human adenocarcinoma cells

Biochemical and Biophysical Research Communications

Volumn 436, Issue 2, 2013, Pages 186-191

  Ono, Misaki ^a   Higuchi, Takako ^a   Takeshima, Mikako ^a   Chen, Chen ^a   Nakano, Shuji ^a  

^a NAKAMURA GAKUEN UNIVERSITY   (Japan)

Author keywords

Apoptosis; Curcumin; G2 M arrest; Ras; Src

Indexed keywords

CURCUMIN; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL XL; PROTEIN KINASE B; RAS PROTEIN; S6 KINASE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CARCINOMA CELL; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL POPULATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DRUG SENSITIVITY; G2 PHASE CELL CYCLE CHECKPOINT; GALLBLADDER CARCINOMA; GENE ACTIVATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; M PHASE CELL CYCLE CHECKPOINT; ONCOGENE RAS; ONCOGENE SRC; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-X PROTEIN; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CURCUMIN; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FLOW CYTOMETRY; G2 PHASE CELL CYCLE CHECKPOINTS; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-AKT; RAS PROTEINS; SRC-FAMILY KINASES;

EID: 84879602866     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.05.071     Document Type: Article

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