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Volumn 41, Issue 7, 2013, Pages 615-626

Telomere length and expression of human telomerase reverse transcriptase splice variants in chronic lymphocytic leukemia

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; MESSENGER RNA; TELOMERASE REVERSE TRANSCRIPTASE;

EID: 84879602744     PISSN: 0301472X     EISSN: 18732399     Source Type: Journal    
DOI: 10.1016/j.exphem.2013.03.008     Document Type: Article
Times cited : (14)

References (49)
  • 1
    • 75649140955 scopus 로고    scopus 로고
    • How I treat CLL up front
    • Gribben J.G. How I treat CLL up front. Blood 2010, 115:187-197.
    • (2010) Blood , vol.115 , pp. 187-197
    • Gribben, J.G.1
  • 2
    • 58349119794 scopus 로고    scopus 로고
    • Prognostic markers in chronic lymphocytic leukemia: a comprehensive review
    • Van Bockstaele F., Verhasselt B., Philippe J. Prognostic markers in chronic lymphocytic leukemia: a comprehensive review. Blood Rev 2009, 23:25-47.
    • (2009) Blood Rev , vol.23 , pp. 25-47
    • Van Bockstaele, F.1    Verhasselt, B.2    Philippe, J.3
  • 4
    • 0027956728 scopus 로고
    • Telomerase activity invivo in human malignant hematopoietic cells
    • Nilsson P., Mehle C., Remes K., Roos G. Telomerase activity invivo in human malignant hematopoietic cells. Oncogene 1994, 9:3043-3048.
    • (1994) Oncogene , vol.9 , pp. 3043-3048
    • Nilsson, P.1    Mehle, C.2    Remes, K.3    Roos, G.4
  • 5
    • 0029066169 scopus 로고
    • Telomerase activity in normal and malignant hematopoietic cells
    • Broccoli D., Young J.W., de Lange T. Telomerase activity in normal and malignant hematopoietic cells. Proc Natl Acad Sci U S A 1995, 92:9082-9086.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 9082-9086
    • Broccoli, D.1    Young, J.W.2    de Lange, T.3
  • 6
    • 78650662899 scopus 로고    scopus 로고
    • Alternative lengthening of telomeres pathway: recombination-mediated telomere maintenance mechanism in human cells
    • Nabetani A., Ishikawa F. Alternative lengthening of telomeres pathway: recombination-mediated telomere maintenance mechanism in human cells. J Biochem 2011, 149:5-14.
    • (2011) J Biochem , vol.149 , pp. 5-14
    • Nabetani, A.1    Ishikawa, F.2
  • 7
    • 23944496667 scopus 로고    scopus 로고
    • Comparison of early passage, senescent and hTERT immortalized endothelial cells
    • Chang M.W., Grillari J., Mayrhofer C., et al. Comparison of early passage, senescent and hTERT immortalized endothelial cells. Exp Cell Res 2005, 309:121-136.
    • (2005) Exp Cell Res , vol.309 , pp. 121-136
    • Chang, M.W.1    Grillari, J.2    Mayrhofer, C.3
  • 8
    • 0028564951 scopus 로고
    • Specific association of human telomerase activity with immortal cells and cancer
    • Kim N.W., Piatyszek M.A., Prowse K.R., et al. Specific association of human telomerase activity with immortal cells and cancer. Science 1994, 266:2011-2015.
    • (1994) Science , vol.266 , pp. 2011-2015
    • Kim, N.W.1    Piatyszek, M.A.2    Prowse, K.R.3
  • 9
    • 0031010342 scopus 로고    scopus 로고
    • A survey of telomerase activity in human cancer
    • Shay J.W., Bacchetti S. A survey of telomerase activity in human cancer. Eur J Cancer 1997, 33:787-791.
    • (1997) Eur J Cancer , vol.33 , pp. 787-791
    • Shay, J.W.1    Bacchetti, S.2
  • 10
    • 0031266490 scopus 로고    scopus 로고
    • Telomerase: a promising marker of biological immortality of germ, stem, and cancer cells. A review
    • Meeker A.K., Coffey D.S. Telomerase: a promising marker of biological immortality of germ, stem, and cancer cells. A review. Biochemistry (Mosc) 1997, 62:1323-1331.
    • (1997) Biochemistry (Mosc) , vol.62 , pp. 1323-1331
    • Meeker, A.K.1    Coffey, D.S.2
  • 11
    • 0032855045 scopus 로고    scopus 로고
    • Telomerase activity in chronic lymphoproliferative disorders of B-cell lineage
    • Trentin L., Ballon G., Ometto L., et al. Telomerase activity in chronic lymphoproliferative disorders of B-cell lineage. Br J Haematol 1999, 106:662-668.
    • (1999) Br J Haematol , vol.106 , pp. 662-668
    • Trentin, L.1    Ballon, G.2    Ometto, L.3
  • 12
    • 9144245353 scopus 로고    scopus 로고
    • Telomere length and telomerase activity delineate distinctive replicative features of the B-CLL subgroups defined by immunoglobulin V gene mutations
    • Damle R.N., Batliwalla F.M., Ghiotto F., et al. Telomere length and telomerase activity delineate distinctive replicative features of the B-CLL subgroups defined by immunoglobulin V gene mutations. Blood 2004, 103:375-382.
    • (2004) Blood , vol.103 , pp. 375-382
    • Damle, R.N.1    Batliwalla, F.M.2    Ghiotto, F.3
  • 13
    • 67349211312 scopus 로고    scopus 로고
    • Telomere length is an independent predictor of survival, treatment requirement and Richter's syndrome transformation in chronic lymphocytic leukemia
    • Rossi D., Lobetti Bodoni C., Genuardi E., et al. Telomere length is an independent predictor of survival, treatment requirement and Richter's syndrome transformation in chronic lymphocytic leukemia. Leukemia 2009, 23:1062-1072.
    • (2009) Leukemia , vol.23 , pp. 1062-1072
    • Rossi, D.1    Lobetti Bodoni, C.2    Genuardi, E.3
  • 14
    • 41349120731 scopus 로고    scopus 로고
    • Short telomeres are associated with genetic complexity, high-risk genomic aberrations, and short survival in chronic lymphocytic leukemia
    • Roos G., Krober A., Grabowski P., et al. Short telomeres are associated with genetic complexity, high-risk genomic aberrations, and short survival in chronic lymphocytic leukemia. Blood 2008, 111:2246-2252.
    • (2008) Blood , vol.111 , pp. 2246-2252
    • Roos, G.1    Krober, A.2    Grabowski, P.3
  • 15
    • 74249092820 scopus 로고    scopus 로고
    • Aberrant telomere structure is characteristic of resistant chronic lymphocytic leukaemia cells
    • Leukemia;24:246-251.
    • Brugat T, Gault N, Baccelli I, etal. Aberrant telomere structure is characteristic of resistant chronic lymphocytic leukaemia cells. Leukemia;24:246-251.
    • Brugat, T.1    Gault, N.2    Baccelli, I.3
  • 16
    • 41349099406 scopus 로고    scopus 로고
    • Changes in the expression of telomere maintenance genes suggest global telomere dysfunction in B-chronic lymphocytic leukemia
    • Poncet D., Belleville A., t'kint de Roodenbeke C., et al. Changes in the expression of telomere maintenance genes suggest global telomere dysfunction in B-chronic lymphocytic leukemia. Blood 2008, 111:2388-2391.
    • (2008) Blood , vol.111 , pp. 2388-2391
    • Poncet, D.1    Belleville, A.2    T'kint de Roodenbeke, C.3
  • 17
    • 0035166456 scopus 로고    scopus 로고
    • Simultaneous flow cytometric analysis of cell surface markers and telomere length: analysis of human tonsilar B cells
    • Batliwalla F.M., Damle R.N., Metz C., Chiorazzi N., Gregersen P.K. Simultaneous flow cytometric analysis of cell surface markers and telomere length: analysis of human tonsilar B cells. J Immunol Methods 2001, 247:103-109.
    • (2001) J Immunol Methods , vol.247 , pp. 103-109
    • Batliwalla, F.M.1    Damle, R.N.2    Metz, C.3    Chiorazzi, N.4    Gregersen, P.K.5
  • 18
    • 0031202137 scopus 로고    scopus 로고
    • Telomerase is up-regulated in human germinal center B cells invivo and can be re-expressed in memory B cells activated invitro
    • Hu B.T., Lee S.C., Marin E., Ryan D.H., Insel R.A. Telomerase is up-regulated in human germinal center B cells invivo and can be re-expressed in memory B cells activated invitro. J Immunol 1997, 159:1068-1071.
    • (1997) J Immunol , vol.159 , pp. 1068-1071
    • Hu, B.T.1    Lee, S.C.2    Marin, E.3    Ryan, D.H.4    Insel, R.A.5
  • 20
    • 0030961087 scopus 로고    scopus 로고
    • Telomere lengthening and telomerase activation during human B cell differentiation
    • Weng N.P., Granger L., Hodes R.J. Telomere lengthening and telomerase activation during human B cell differentiation. Proc Natl Acad Sci U S A 1997, 94:10827-10832.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 10827-10832
    • Weng, N.P.1    Granger, L.2    Hodes, R.J.3
  • 21
    • 84866547889 scopus 로고    scopus 로고
    • T-cell independent, B-cell receptor-mediated induction of telomerase activity differs among IGHV mutation-based subgroups of chronic lymphocytic leukemia patients
    • Damle R.N., Temburni S., Banapour T., et al. T-cell independent, B-cell receptor-mediated induction of telomerase activity differs among IGHV mutation-based subgroups of chronic lymphocytic leukemia patients. Blood 2012, 120:2438-2449.
    • (2012) Blood , vol.120 , pp. 2438-2449
    • Damle, R.N.1    Temburni, S.2    Banapour, T.3
  • 22
    • 0030745448 scopus 로고    scopus 로고
    • HEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization
    • Meyerson M., Counter C.M., Eaton E.N., et al. hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Cell 1997, 90:785-795.
    • (1997) Cell , vol.90 , pp. 785-795
    • Meyerson, M.1    Counter, C.M.2    Eaton, E.N.3
  • 23
    • 0035187677 scopus 로고    scopus 로고
    • The significance of human telomerase reverse transcriptase (hTERT) in cancer
    • Kirkpatrick K.L., Mokbel K. The significance of human telomerase reverse transcriptase (hTERT) in cancer. Eur J Surg Oncol 2001, 27:754-760.
    • (2001) Eur J Surg Oncol , vol.27 , pp. 754-760
    • Kirkpatrick, K.L.1    Mokbel, K.2
  • 25
    • 34247622889 scopus 로고    scopus 로고
    • Telomerase expression in B-cell chronic lymphocytic leukemia predicts survival and delineates subgroups of patients with the same igVH mutation status and different outcome
    • Terrin L., Trentin L., Degan M., et al. Telomerase expression in B-cell chronic lymphocytic leukemia predicts survival and delineates subgroups of patients with the same igVH mutation status and different outcome. Leukemia 2007, 21:965-972.
    • (2007) Leukemia , vol.21 , pp. 965-972
    • Terrin, L.1    Trentin, L.2    Degan, M.3
  • 26
    • 33748675710 scopus 로고    scopus 로고
    • Characterization of novel alternative splicing sites in human telomerase reverse transcriptase (hTERT): Analysis of expression and mutual correlation in mRNA isoforms from normal and tumour tissues
    • Saeboe-Larssen S., Fossberg E., Gaudernack G. Characterization of novel alternative splicing sites in human telomerase reverse transcriptase (hTERT): Analysis of expression and mutual correlation in mRNA isoforms from normal and tumour tissues. BMC Mol Biol 2006, 7:26.
    • (2006) BMC Mol Biol , vol.7 , pp. 26
    • Saeboe-Larssen, S.1    Fossberg, E.2    Gaudernack, G.3
  • 27
    • 0032530136 scopus 로고    scopus 로고
    • Telomerase activity in human development is regulated by human telomerase reverse transcriptase (hTERT) transcription and by alternate splicing of hTERT transcripts
    • Ulaner G.A., Hu J.F., Vu T.H., Giudice L.C., Hoffman A.R. Telomerase activity in human development is regulated by human telomerase reverse transcriptase (hTERT) transcription and by alternate splicing of hTERT transcripts. Cancer Res 1998, 58:4168-4172.
    • (1998) Cancer Res , vol.58 , pp. 4168-4172
    • Ulaner, G.A.1    Hu, J.F.2    Vu, T.H.3    Giudice, L.C.4    Hoffman, A.R.5
  • 28
    • 0035283896 scopus 로고    scopus 로고
    • Tissue-specific alternate splicing of human telomerase reverse transcriptase (hTERT) influences telomere lengths during human development
    • Ulaner G.A., Hu J.F., Vu T.H., Giudice L.C., Hoffman A.R. Tissue-specific alternate splicing of human telomerase reverse transcriptase (hTERT) influences telomere lengths during human development. Int J Cancer 2001, 91:644-649.
    • (2001) Int J Cancer , vol.91 , pp. 644-649
    • Ulaner, G.A.1    Hu, J.F.2    Vu, T.H.3    Giudice, L.C.4    Hoffman, A.R.5
  • 29
    • 0033988011 scopus 로고    scopus 로고
    • Regulation of telomerase by alternate splicing of human telomerase reverse transcriptase (hTERT) in normal and neoplastic ovary, endometrium and myometrium
    • Ulaner G.A., Hu J.F., Vu T.H., Oruganti H., Giudice L.C., Hoffman A.R. Regulation of telomerase by alternate splicing of human telomerase reverse transcriptase (hTERT) in normal and neoplastic ovary, endometrium and myometrium. Int J Cancer 2000, 85:330-335.
    • (2000) Int J Cancer , vol.85 , pp. 330-335
    • Ulaner, G.A.1    Hu, J.F.2    Vu, T.H.3    Oruganti, H.4    Giudice, L.C.5    Hoffman, A.R.6
  • 31
    • 0034523665 scopus 로고    scopus 로고
    • An alternate splicing variant of the human telomerase catalytic subunit inhibits telomerase activity
    • Yi X., White D.M., Aisner D.L., Baur J.A., Wright W.E., Shay J.W. An alternate splicing variant of the human telomerase catalytic subunit inhibits telomerase activity. Neoplasia 2000, 2:433-440.
    • (2000) Neoplasia , vol.2 , pp. 433-440
    • Yi, X.1    White, D.M.2    Aisner, D.L.3    Baur, J.A.4    Wright, W.E.5    Shay, J.W.6
  • 32
    • 6944225267 scopus 로고    scopus 로고
    • HTERT expression and prognosis in B-chronic lymphocytic leukemia
    • Tchirkov A., Chaleteix C., Magnac C., et al. hTERT expression and prognosis in B-chronic lymphocytic leukemia. Ann Oncol 2004, 15:1476-1480.
    • (2004) Ann Oncol , vol.15 , pp. 1476-1480
    • Tchirkov, A.1    Chaleteix, C.2    Magnac, C.3
  • 33
    • 0036467499 scopus 로고    scopus 로고
    • Telomerase regulation: not just flipping the switch
    • Aisner D.L., Wright W.E., Shay J.W. Telomerase regulation: not just flipping the switch. Curr Opin Genet Dev 2002, 12:80-85.
    • (2002) Curr Opin Genet Dev , vol.12 , pp. 80-85
    • Aisner, D.L.1    Wright, W.E.2    Shay, J.W.3
  • 34
    • 20444463109 scopus 로고    scopus 로고
    • Differential expression of full-length telomerase reverse transcriptase mRNA and telomerase activity between normal and malignant renal tissues
    • Fan Y., Liu Z., Fang X., et al. Differential expression of full-length telomerase reverse transcriptase mRNA and telomerase activity between normal and malignant renal tissues. Clin Cancer Res 2005, 11:4331-4337.
    • (2005) Clin Cancer Res , vol.11 , pp. 4331-4337
    • Fan, Y.1    Liu, Z.2    Fang, X.3
  • 35
    • 0037148327 scopus 로고    scopus 로고
    • Complex regulatory mechanisms of telomerase activity in normal and cancer cells: how can we apply them for cancer therapy?
    • Kyo S., Inoue M. Complex regulatory mechanisms of telomerase activity in normal and cancer cells: how can we apply them for cancer therapy?. Oncogene 2002, 21:688-697.
    • (2002) Oncogene , vol.21 , pp. 688-697
    • Kyo, S.1    Inoue, M.2
  • 36
  • 37
    • 45149100665 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines
    • Hallek M., Cheson B.D., Catovsky D., et al. Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines. Blood 2008, 111:5446-5456.
    • (2008) Blood , vol.111 , pp. 5446-5456
    • Hallek, M.1    Cheson, B.D.2    Catovsky, D.3
  • 38
    • 64149097786 scopus 로고    scopus 로고
    • The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments
    • Bustin S.A., Benes V., Garson J.A., et al. The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin Chem 2009, 55:611-622.
    • (2009) Clin Chem , vol.55 , pp. 611-622
    • Bustin, S.A.1    Benes, V.2    Garson, J.A.3
  • 39
    • 33846349566 scopus 로고    scopus 로고
    • Telomerase (hTERT 611-626) serves as a tumor antigen in B-cell chronic lymphocytic leukemia and generates spontaneously antileukemic, cytotoxic T cells
    • Kokhaei P., Palma M., Hansson L., Osterborg A., Mellstedt H., Choudhury A. Telomerase (hTERT 611-626) serves as a tumor antigen in B-cell chronic lymphocytic leukemia and generates spontaneously antileukemic, cytotoxic T cells. Exp Hematol 2007, 35:297-304.
    • (2007) Exp Hematol , vol.35 , pp. 297-304
    • Kokhaei, P.1    Palma, M.2    Hansson, L.3    Osterborg, A.4    Mellstedt, H.5    Choudhury, A.6
  • 40
    • 63349111567 scopus 로고    scopus 로고
    • Telomere length measurement by a novel monochrome multiplex quantitative PCR method
    • Cawthon R.M. Telomere length measurement by a novel monochrome multiplex quantitative PCR method. Nucleic Acids Res 2009, 37:e21.
    • (2009) Nucleic Acids Res , vol.37
    • Cawthon, R.M.1
  • 41
    • 20444382051 scopus 로고    scopus 로고
    • Telomere length as a prognostic parameter in chronic lymphocytic leukemia with special reference to VH gene mutation status
    • Grabowski P., Hultdin M., Karlsson K., et al. Telomere length as a prognostic parameter in chronic lymphocytic leukemia with special reference to VH gene mutation status. Blood 2005, 105:4807-4812.
    • (2005) Blood , vol.105 , pp. 4807-4812
    • Grabowski, P.1    Hultdin, M.2    Karlsson, K.3
  • 42
    • 0037463240 scopus 로고    scopus 로고
    • Association between telomere length and V(H) gene mutation status in chronic lymphocytic leukaemia: clinical and biological implications
    • Hultdin M., Rosenquist R., Thunberg U., et al. Association between telomere length and V(H) gene mutation status in chronic lymphocytic leukaemia: clinical and biological implications. Br J Cancer 2003, 88:593-598.
    • (2003) Br J Cancer , vol.88 , pp. 593-598
    • Hultdin, M.1    Rosenquist, R.2    Thunberg, U.3
  • 43
    • 0035584117 scopus 로고    scopus 로고
    • Quantitation of telomerase components and hTERT mRNA splicing patterns in immortal human cells
    • Yi X., Shay J.W., Wright W.E. Quantitation of telomerase components and hTERT mRNA splicing patterns in immortal human cells. Nucleic Acids Res 2001, 29:4818-4825.
    • (2001) Nucleic Acids Res , vol.29 , pp. 4818-4825
    • Yi, X.1    Shay, J.W.2    Wright, W.E.3
  • 44
    • 0036724354 scopus 로고    scopus 로고
    • Transcription and alternative splicing of telomerase reverse transcriptase in benign and malignant breast tumours and in adjacent mammary glandular tissues: implications for telomerase activity
    • Zaffaroni N., Della Porta C., Villa R., et al. Transcription and alternative splicing of telomerase reverse transcriptase in benign and malignant breast tumours and in adjacent mammary glandular tissues: implications for telomerase activity. J Pathol 2002, 198:37-46.
    • (2002) J Pathol , vol.198 , pp. 37-46
    • Zaffaroni, N.1    Della Porta, C.2    Villa, R.3
  • 45
    • 33845965382 scopus 로고    scopus 로고
    • Real-time RT-PCR quantification of human telomerase reverse transcriptase splice variants in tumor cell lines and non-small cell lung cancer
    • Mavrogiannou E., Strati A., Stathopoulou A., Tsaroucha E.G., Kaklamanis L., Lianidou E.S. Real-time RT-PCR quantification of human telomerase reverse transcriptase splice variants in tumor cell lines and non-small cell lung cancer. Clin Chem 2007, 53:53-61.
    • (2007) Clin Chem , vol.53 , pp. 53-61
    • Mavrogiannou, E.1    Strati, A.2    Stathopoulou, A.3    Tsaroucha, E.G.4    Kaklamanis, L.5    Lianidou, E.S.6
  • 46
    • 54249156408 scopus 로고    scopus 로고
    • Quantification of hTERT splice variants in melanoma by SYBR green real-time polymerase chain reaction indicates a negative regulatory role for the beta deletion variant
    • Lincz L.F., Mudge L.M., Scorgie F.E., Sakoff J.A., Hamilton C.S., Seldon M. Quantification of hTERT splice variants in melanoma by SYBR green real-time polymerase chain reaction indicates a negative regulatory role for the beta deletion variant. Neoplasia 2008, 10:1131-1137.
    • (2008) Neoplasia , vol.10 , pp. 1131-1137
    • Lincz, L.F.1    Mudge, L.M.2    Scorgie, F.E.3    Sakoff, J.A.4    Hamilton, C.S.5    Seldon, M.6
  • 47
    • 53649101072 scopus 로고    scopus 로고
    • Differentiating alternative splice variant patterns of human telomerase reverse transcriptase in thyroid neoplasms
    • Wang Y., Kowalski J., Tsai H.L., et al. Differentiating alternative splice variant patterns of human telomerase reverse transcriptase in thyroid neoplasms. Thyroid 2008, 18:1055-1063.
    • (2008) Thyroid , vol.18 , pp. 1055-1063
    • Wang, Y.1    Kowalski, J.2    Tsai, H.L.3
  • 48
    • 3042642783 scopus 로고    scopus 로고
    • Splice variants as cancer biomarkers
    • Brinkman B.M. Splice variants as cancer biomarkers. Clin Biochem 2004, 37:584-594.
    • (2004) Clin Biochem , vol.37 , pp. 584-594
    • Brinkman, B.M.1


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