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Volumn 35, Issue 2, 2007, Pages 297-304

Telomerase (hTERT 611-626) serves as a tumor antigen in B-cell chronic lymphocytic leukemia and generates spontaneously antileukemic, cytotoxic T cells

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; RAS PROTEIN; TELOMERASE; TUMOR ANTIGEN;

EID: 33846349566     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exphem.2006.10.006     Document Type: Article
Times cited : (50)

References (39)
  • 1
    • 0030819894 scopus 로고    scopus 로고
    • Telomerase catalytic subunit homologs from fission yeast and human
    • Nakamura T.M., Morin G.B., Chapman K.B., et al. Telomerase catalytic subunit homologs from fission yeast and human. Science 277 (1997) 955-959
    • (1997) Science , vol.277 , pp. 955-959
    • Nakamura, T.M.1    Morin, G.B.2    Chapman, K.B.3
  • 2
    • 0032522443 scopus 로고    scopus 로고
    • The telomerase reverse transcriptase: components and regulation
    • Nugent C.I., and Lundblad V. The telomerase reverse transcriptase: components and regulation. Genes Dev 12 (1998) 1073-1085
    • (1998) Genes Dev , vol.12 , pp. 1073-1085
    • Nugent, C.I.1    Lundblad, V.2
  • 3
    • 0037148271 scopus 로고    scopus 로고
    • Telomerase in the human organism
    • Collins K., and Mitchell J.R. Telomerase in the human organism. Oncogene 21 (2002) 564-579
    • (2002) Oncogene , vol.21 , pp. 564-579
    • Collins, K.1    Mitchell, J.R.2
  • 4
    • 0037102234 scopus 로고    scopus 로고
    • Different telomere damage signaling pathways in human and mouse cells
    • Smogorzewska A., and de Lange T. Different telomere damage signaling pathways in human and mouse cells. EMBO J 21 (2002) 4338-4348
    • (2002) EMBO J , vol.21 , pp. 4338-4348
    • Smogorzewska, A.1    de Lange, T.2
  • 5
    • 0028564951 scopus 로고
    • Specific association of human telomerase activity with immortal cells and cancer
    • Kim N.W., Piatyszek M.A., Prowse K.R., et al. Specific association of human telomerase activity with immortal cells and cancer. Science 266 (1994) 2011-2015
    • (1994) Science , vol.266 , pp. 2011-2015
    • Kim, N.W.1    Piatyszek, M.A.2    Prowse, K.R.3
  • 6
    • 0031010342 scopus 로고    scopus 로고
    • A survey of telomerase activity in human cancer
    • Shay J.W., and Bacchetti S. A survey of telomerase activity in human cancer. Eur J Cancer 33 (1997) 787-791
    • (1997) Eur J Cancer , vol.33 , pp. 787-791
    • Shay, J.W.1    Bacchetti, S.2
  • 7
    • 0028198679 scopus 로고
    • Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes
    • Counter C.M., Botelho F.M., Wang P., Harley C.B., and Bacchetti S. Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes. J Virol 68 (1994) 3410-3414
    • (1994) J Virol , vol.68 , pp. 3410-3414
    • Counter, C.M.1    Botelho, F.M.2    Wang, P.3    Harley, C.B.4    Bacchetti, S.5
  • 8
    • 0026523228 scopus 로고
    • Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
    • Counter C.M., Avilion A.A., LeFeuvre C.E., et al. Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J 11 (1992) 1921-1929
    • (1992) EMBO J , vol.11 , pp. 1921-1929
    • Counter, C.M.1    Avilion, A.A.2    LeFeuvre, C.E.3
  • 9
    • 0030668722 scopus 로고    scopus 로고
    • Human telomerase contains evolutionarily conserved catalytic and structural subunits
    • Harrington L., Zhou W., McPhail T., et al. Human telomerase contains evolutionarily conserved catalytic and structural subunits. Genes Dev 11 (1997) 3109-3115
    • (1997) Genes Dev , vol.11 , pp. 3109-3115
    • Harrington, L.1    Zhou, W.2    McPhail, T.3
  • 10
    • 0030745448 scopus 로고    scopus 로고
    • hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization
    • Meyerson M., Counter C.M., Eaton E.N., et al. hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Cell 90 (1997) 785-795
    • (1997) Cell , vol.90 , pp. 785-795
    • Meyerson, M.1    Counter, C.M.2    Eaton, E.N.3
  • 11
    • 0028938262 scopus 로고
    • Telomerase activity in normal leukocytes and in hematologic malignancies
    • Counter C.M., Gupta J., Harley C.B., Leber B., and Bacchetti S. Telomerase activity in normal leukocytes and in hematologic malignancies. Blood 85 (1995) 2315-2320
    • (1995) Blood , vol.85 , pp. 2315-2320
    • Counter, C.M.1    Gupta, J.2    Harley, C.B.3    Leber, B.4    Bacchetti, S.5
  • 13
    • 0032855045 scopus 로고    scopus 로고
    • Telomerase activity in chronic lymphoproliferative disorders of B-cell lineage
    • Trentin L., Ballon G., Ometto L., et al. Telomerase activity in chronic lymphoproliferative disorders of B-cell lineage. Br J Haematol 106 (1999) 662-668
    • (1999) Br J Haematol , vol.106 , pp. 662-668
    • Trentin, L.1    Ballon, G.2    Ometto, L.3
  • 14
    • 9144245353 scopus 로고    scopus 로고
    • Telomere length and telomerase activity delineate distinctive replicative features of the B-CLL subgroups defined by immunoglobulin V gene mutations
    • Damle R.N., Batliwalla F.M., Ghiotto F., et al. Telomere length and telomerase activity delineate distinctive replicative features of the B-CLL subgroups defined by immunoglobulin V gene mutations. Blood 103 (2004) 375-382
    • (2004) Blood , vol.103 , pp. 375-382
    • Damle, R.N.1    Batliwalla, F.M.2    Ghiotto, F.3
  • 15
    • 0029981025 scopus 로고    scopus 로고
    • National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment
    • Cheson B.D., Bennett J.M., Grever M., et al. National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment. Blood 87 (1996) 4990-4997
    • (1996) Blood , vol.87 , pp. 4990-4997
    • Cheson, B.D.1    Bennett, J.M.2    Grever, M.3
  • 16
    • 8844246393 scopus 로고    scopus 로고
    • Apoptotic tumor cells are superior to tumor cell lysate, and tumor cell RNA in induction of autologous T cell response in B-CLL
    • Kokhaei P., Choudhury A., Mahdian R., et al. Apoptotic tumor cells are superior to tumor cell lysate, and tumor cell RNA in induction of autologous T cell response in B-CLL. Leukemia 18 (2004) 1810-1815
    • (2004) Leukemia , vol.18 , pp. 1810-1815
    • Kokhaei, P.1    Choudhury, A.2    Mahdian, R.3
  • 18
    • 33745638729 scopus 로고    scopus 로고
    • Telomerase peptide vaccination: a phase I/II study in patients with non-small cell lung cancer
    • Brunsvig P.F., Aamdal S., Gjertsen M.K., et al. Telomerase peptide vaccination: a phase I/II study in patients with non-small cell lung cancer. Cancer Immunol Immunother 55 (2006) 1553-1564
    • (2006) Cancer Immunol Immunother , vol.55 , pp. 1553-1564
    • Brunsvig, P.F.1    Aamdal, S.2    Gjertsen, M.K.3
  • 19
    • 0037851825 scopus 로고    scopus 로고
    • Dendritic cells loaded with apoptotic tumour cells induce a stronger T-cell response than dendritic cell-tumour hybrids in B-CLL
    • Kokhaei P., Rezvany M.R., Virving L., et al. Dendritic cells loaded with apoptotic tumour cells induce a stronger T-cell response than dendritic cell-tumour hybrids in B-CLL. Leukemia 17 (2003) 894-899
    • (2003) Leukemia , vol.17 , pp. 894-899
    • Kokhaei, P.1    Rezvany, M.R.2    Virving, L.3
  • 20
    • 0034767717 scopus 로고    scopus 로고
    • Standardized generation of fully mature p70 IL-12 secreting monocyte-derived dendritic cells for clinical use
    • Spisek R., Bretaudeau L., Barbieux I., Meflah K., and Gregoire M. Standardized generation of fully mature p70 IL-12 secreting monocyte-derived dendritic cells for clinical use. Cancer Immunol Immunother 50 (2001) 417-427
    • (2001) Cancer Immunol Immunother , vol.50 , pp. 417-427
    • Spisek, R.1    Bretaudeau, L.2    Barbieux, I.3    Meflah, K.4    Gregoire, M.5
  • 21
    • 0043239287 scopus 로고    scopus 로고
    • The flow cytometric PKH-26 assay for the determination of T-cell mediated cytotoxic activity
    • Fischer K., and Mackensen A. The flow cytometric PKH-26 assay for the determination of T-cell mediated cytotoxic activity. Methods 31 (2003) 135-142
    • (2003) Methods , vol.31 , pp. 135-142
    • Fischer, K.1    Mackensen, A.2
  • 22
    • 6944225267 scopus 로고    scopus 로고
    • hTERT expression and prognosis in B-chronic lymphocytic leukemia
    • Tchirkov A., Chaleteix C., Magnac C., et al. hTERT expression and prognosis in B-chronic lymphocytic leukemia. Ann Oncol 15 (2004) 1476-1480
    • (2004) Ann Oncol , vol.15 , pp. 1476-1480
    • Tchirkov, A.1    Chaleteix, C.2    Magnac, C.3
  • 23
    • 2442467905 scopus 로고    scopus 로고
    • Telomerase activity is not a prognostic factor in chronic lymphocytic leukemia
    • Verstovsek S., Giles F.J., O'Brien S., et al. Telomerase activity is not a prognostic factor in chronic lymphocytic leukemia. Leuk Res 28 (2004) 707-711
    • (2004) Leuk Res , vol.28 , pp. 707-711
    • Verstovsek, S.1    Giles, F.J.2    O'Brien, S.3
  • 24
    • 0037463240 scopus 로고    scopus 로고
    • Association between telomere length and V(H) gene mutation status in chronic lymphocytic leukaemia: clinical and biological implications
    • Hultdin M., Rosenquist R., Thunberg U., et al. Association between telomere length and V(H) gene mutation status in chronic lymphocytic leukaemia: clinical and biological implications. Br J Cancer 88 (2003) 593-598
    • (2003) Br J Cancer , vol.88 , pp. 593-598
    • Hultdin, M.1    Rosenquist, R.2    Thunberg, U.3
  • 25
    • 20444382051 scopus 로고    scopus 로고
    • Telomere length as a prognostic parameter in chronic lymphocytic leukemia with special reference to VH gene mutation status
    • Grabowski P., Hultdin M., Karlsson K., et al. Telomere length as a prognostic parameter in chronic lymphocytic leukemia with special reference to VH gene mutation status. Blood 105 (2005) 4807-4812
    • (2005) Blood , vol.105 , pp. 4807-4812
    • Grabowski, P.1    Hultdin, M.2    Karlsson, K.3
  • 26
    • 0030998216 scopus 로고    scopus 로고
    • Telomeres and telomerase in normal and malignant haematopoietic cells
    • Norrback K.F., and Roos G. Telomeres and telomerase in normal and malignant haematopoietic cells. Eur J Cancer 33 (1997) 774-780
    • (1997) Eur J Cancer , vol.33 , pp. 774-780
    • Norrback, K.F.1    Roos, G.2
  • 27
    • 0037251836 scopus 로고    scopus 로고
    • Activity and expression of human telomerase in normal and malignant cells in gastric and colon cancer patients
    • Nowak J., Januszkiewicz D., Lewandowski K., et al. Activity and expression of human telomerase in normal and malignant cells in gastric and colon cancer patients. Eur J Gastroenterol Hepatol 15 (2003) 75-80
    • (2003) Eur J Gastroenterol Hepatol , vol.15 , pp. 75-80
    • Nowak, J.1    Januszkiewicz, D.2    Lewandowski, K.3
  • 28
    • 0035353178 scopus 로고    scopus 로고
    • Identification of human telomerase reverse transcriptase-derived peptides that induce HLA-A24-restricted antileukemia cytotoxic T lymphocytes
    • Arai J., Yasukawa M., Ohminami H., et al. Identification of human telomerase reverse transcriptase-derived peptides that induce HLA-A24-restricted antileukemia cytotoxic T lymphocytes. Blood 97 (2001) 2903-2907
    • (2001) Blood , vol.97 , pp. 2903-2907
    • Arai, J.1    Yasukawa, M.2    Ohminami, H.3
  • 29
    • 0034712848 scopus 로고    scopus 로고
    • Cytotoxic T cell immunity against telomerase reverse transcriptase in humans
    • Minev B., Hipp J., Firat H., et al. Cytotoxic T cell immunity against telomerase reverse transcriptase in humans. Proc Natl Acad Sci U S A 97 (2000) 4796-4801
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 4796-4801
    • Minev, B.1    Hipp, J.2    Firat, H.3
  • 30
    • 2442455516 scopus 로고    scopus 로고
    • Interferon-gamma differentially regulates susceptibility of lung cancer cells to telomerase-specific cytotoxic T lymphocytes
    • Tajima K., Ito Y., Demachi A., et al. Interferon-gamma differentially regulates susceptibility of lung cancer cells to telomerase-specific cytotoxic T lymphocytes. Int J Cancer 110 (2004) 403-412
    • (2004) Int J Cancer , vol.110 , pp. 403-412
    • Tajima, K.1    Ito, Y.2    Demachi, A.3
  • 31
    • 10744221022 scopus 로고    scopus 로고
    • Vaccination of cancer patients against telomerase induces functional antitumor CD8+ T lymphocytes
    • Vonderheide R.H., Domchek S.M., Schultze J.L., et al. Vaccination of cancer patients against telomerase induces functional antitumor CD8+ T lymphocytes. Clin Cancer Res 10 (2004) 828-839
    • (2004) Clin Cancer Res , vol.10 , pp. 828-839
    • Vonderheide, R.H.1    Domchek, S.M.2    Schultze, J.L.3
  • 32
    • 3242690518 scopus 로고    scopus 로고
    • Immunization of patients with the hTERT:540-548 peptide induces peptide-reactive T lymphocytes that do not recognize tumors endogenously expressing telomerase
    • Parkhurst M.R., Riley J.P., Igarashi T., et al. Immunization of patients with the hTERT:540-548 peptide induces peptide-reactive T lymphocytes that do not recognize tumors endogenously expressing telomerase. Clin Cancer Res 10 (2004) 4688-4698
    • (2004) Clin Cancer Res , vol.10 , pp. 4688-4698
    • Parkhurst, M.R.1    Riley, J.P.2    Igarashi, T.3
  • 33
    • 33846354202 scopus 로고    scopus 로고
    • Gaudernack G, Buanes T, Meo M, et al. Clinical trials of a peptide based vaccine targeting telomerase [abstract]. Proceedings of the Annual Meeting of the American Society of Clinical Oncology. 2003;Abstract 666.
  • 34
    • 24944476490 scopus 로고    scopus 로고
    • CD4+ T lymphocytes: a critical component of antitumor immunity
    • Ostrand-Rosenberg S. CD4+ T lymphocytes: a critical component of antitumor immunity. Cancer Invest 23 (2005) 413-419
    • (2005) Cancer Invest , vol.23 , pp. 413-419
    • Ostrand-Rosenberg, S.1
  • 35
    • 0036782884 scopus 로고    scopus 로고
    • Telomerase: a target for cancer therapeutics
    • Shay J.W., and Wright W.E. Telomerase: a target for cancer therapeutics. Cancer Cell 2 (2002) 257-265
    • (2002) Cancer Cell , vol.2 , pp. 257-265
    • Shay, J.W.1    Wright, W.E.2
  • 36
    • 21244467877 scopus 로고    scopus 로고
    • A phase I/II trial of oxidized autologous tumor vaccines during the "watch and wait" phase of chronic lymphocytic leukemia
    • Spaner D.E., Hammond C., Mena J., Foden C., and Deabreu A. A phase I/II trial of oxidized autologous tumor vaccines during the "watch and wait" phase of chronic lymphocytic leukemia. Cancer Immunol Immunother 54 (2005) 635-646
    • (2005) Cancer Immunol Immunother , vol.54 , pp. 635-646
    • Spaner, D.E.1    Hammond, C.2    Mena, J.3    Foden, C.4    Deabreu, A.5
  • 37
    • 26944462424 scopus 로고    scopus 로고
    • Allogeneic dendritic cells pulsed with tumor lysates or apoptotic bodies as immunotherapy for patients with early-stage B-cell chronic lymphocytic leukemia
    • Hus I., Rolinski J., Tabarkiewicz J., et al. Allogeneic dendritic cells pulsed with tumor lysates or apoptotic bodies as immunotherapy for patients with early-stage B-cell chronic lymphocytic leukemia. Leukemia 19 (2005) 1621-1627
    • (2005) Leukemia , vol.19 , pp. 1621-1627
    • Hus, I.1    Rolinski, J.2    Tabarkiewicz, J.3
  • 38
    • 0033765797 scopus 로고    scopus 로고
    • Autologous T lymphocytes recognize the tumour-derived immunoglobulin VH-CDR3 region in patients with B-cell chronic lymphocytic leukaemia
    • Rezvany M.R., Jeddi-Tehrani M., Rabbani H., et al. Autologous T lymphocytes recognize the tumour-derived immunoglobulin VH-CDR3 region in patients with B-cell chronic lymphocytic leukaemia. Br J Haematol 111 (2000) 230-238
    • (2000) Br J Haematol , vol.111 , pp. 230-238
    • Rezvany, M.R.1    Jeddi-Tehrani, M.2    Rabbani, H.3
  • 39
    • 0036739731 scopus 로고    scopus 로고
    • Idiotypic vaccination for B-cell malignancies as a model for therapeutic cancer vaccines: from prototype protein to second generation vaccines
    • Ruffini P.A., Neelapu S.S., Kwak L.W., and Biragyn A. Idiotypic vaccination for B-cell malignancies as a model for therapeutic cancer vaccines: from prototype protein to second generation vaccines. Haematologica 87 (2002) 989-1001
    • (2002) Haematologica , vol.87 , pp. 989-1001
    • Ruffini, P.A.1    Neelapu, S.S.2    Kwak, L.W.3    Biragyn, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.