-
1
-
-
34147135183
-
Karyotype is an independent prognostic factor in adult acute lymphoblastic leukemia (ALL): Analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) UKALLXII/Eastern Cooperative Oncology Group (ECOG) 2993 Trial
-
Moorman AV, Harrison CJ, Buck GA, et al: Karyotype is an independent prognostic factor in adult acute lymphoblastic leukemia (ALL): Analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) UKALLXII/Eastern Cooperative Oncology Group (ECOG) 2993 Trial. Blood 109:3189-3197, 2007
-
(2007)
Blood
, vol.109
, pp. 3189-3197
-
-
Moorman, A.V.1
Harrison, C.J.2
Buck, G.A.3
-
2
-
-
41949083910
-
Impact of cytogenetics on the outcome of adult acute lymphoblastic leukemia: Results of Southwest Oncology Group 9400 study
-
Pullarkat V, Slovak ML, Kopecky KJ, et al: Impact of cytogenetics on the outcome of adult acute lymphoblastic leukemia: Results of Southwest Oncology Group 9400 study. Blood 111:2563-2572, 2008
-
(2008)
Blood
, vol.111
, pp. 2563-2572
-
-
Pullarkat, V.1
Slovak, M.L.2
Kopecky, K.J.3
-
3
-
-
79952095577
-
Modern therapy of acute lymphoblastic leukemia
-
Bassan R, Hoelzer D: Modern therapy of acute lymphoblastic leukemia. J Clin Oncol 29:532-543, 2011
-
(2011)
J Clin Oncol
, vol.29
, pp. 532-543
-
-
Bassan, R.1
Hoelzer, D.2
-
4
-
-
58649087583
-
Optimal management of adults with ALL
-
Rowe JM: Optimal management of adults with ALL. Br J Haematol 144:468-483, 2009
-
(2009)
Br J Haematol
, vol.144
, pp. 468-483
-
-
Rowe, J.M.1
-
5
-
-
62549141516
-
A novel translocation, t(14;19)(q32;p13), involving IGH@ and the cytokine receptor for erythropoietin
-
Russell LJ, De Castro DG, Griffiths M, et al: A novel translocation, t(14;19)(q32;p13), involving IGH@ and the cytokine receptor for erythropoietin. Leukemia 23:614-617, 2009
-
(2009)
Leukemia
, vol.23
, pp. 614-617
-
-
Russell, L.J.1
De Castro, D.G.2
Griffiths, M.3
-
6
-
-
70350519430
-
Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia
-
Russell LJ, Capasso M, Vater I, et al: Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia. Blood 114:2688-2698, 2009
-
(2009)
Blood
, vol.114
, pp. 2688-2698
-
-
Russell, L.J.1
Capasso, M.2
Vater, I.3
-
7
-
-
38049126095
-
t(6;14)(p22;q32): A new recurrent IGH@ translocation involving ID4 in B-cell precursor acute lymphoblastic leukemia (BCP-ALL)
-
Russell LJ, Akasaka T, Majid A, et al: t(6;14)(p22;q32): A new recurrent IGH@ translocation involving ID4 in B-cell precursor acute lymphoblastic leukemia (BCP-ALL). Blood 111:387-391, 2008
-
(2008)
Blood
, vol.111
, pp. 387-391
-
-
Russell, L.J.1
Akasaka, T.2
Majid, A.3
-
8
-
-
34147161800
-
Five members of the CEBP transcription factor family are targeted by recurrent IGH translocations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL)
-
Akasaka T, Balasas T, Russell LJ, et al: Five members of the CEBP transcription factor family are targeted by recurrent IGH translocations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL). Blood 109:3451-3461, 2007
-
(2007)
Blood
, vol.109
, pp. 3451-3461
-
-
Akasaka, T.1
Balasas, T.2
Russell, L.J.3
-
9
-
-
33751196596
-
Overexpression of CEBPA resulting from the translocation t(14;19)(q32;q13) of human precursor B acute lymphoblastic leukemia
-
Chapiro E, Russell L, Radford-Weiss I, et al: Overexpression of CEBPA resulting from the translocation t(14;19)(q32;q13) of human precursor B acute lymphoblastic leukemia. Blood 108:3560-3563, 2006
-
(2006)
Blood
, vol.108
, pp. 3560-3563
-
-
Chapiro, E.1
Russell, L.2
Radford-Weiss, I.3
-
10
-
-
77954658856
-
A new recurrent translocation t(11;14)(q24;q32) involving IGH@ and miR-125b-1 in B-cell progenitor acute lymphoblastic leukemia
-
Chapiro E, Russell LJ, Struski S, et al: A new recurrent translocation t(11;14)(q24;q32) involving IGH@ and miR-125b-1 in B-cell progenitor acute lymphoblastic leukemia. Leukemia 24:1362-1364, 2010
-
(2010)
Leukemia
, vol.24
, pp. 1362-1364
-
-
Chapiro, E.1
Russell, L.J.2
Struski, S.3
-
11
-
-
77949425065
-
Activating mutation in the TSLPR gene in B-cell precursor lymphoblastic leukemia
-
Chapiro E, Russell L, Lainey E, et al: Activating mutation in the TSLPR gene in B-cell precursor lymphoblastic leukemia. Leukemia 24:642-645, 2010
-
(2010)
Leukemia
, vol.24
, pp. 642-645
-
-
Chapiro, E.1
Russell, L.2
Lainey, E.3
-
12
-
-
77649214639
-
Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: A report from the International BFM Study Group
-
Hertzberg L, Vendramini E, Ganmore I, et al: Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: A report from the International BFM Study Group. Blood 115:1006-1017, 2010
-
(2010)
Blood
, vol.115
, pp. 1006-1017
-
-
Hertzberg, L.1
Vendramini, E.2
Ganmore, I.3
-
13
-
-
70350680415
-
Rearrangement of CRLF2 in B-progenitorand Down syndrome-associated acute lymphoblastic leukemia
-
Mullighan CG, Collins-Underwood JR, Phillips LA, et al: Rearrangement of CRLF2 in B-progenitorand Down syndrome-associated acute lymphoblastic leukemia. Nat Genet 41:1243-1246, 2009
-
(2009)
Nat Genet
, vol.41
, pp. 1243-1246
-
-
Mullighan, C.G.1
Collins-Underwood, J.R.2
Phillips, L.A.3
-
14
-
-
77949910163
-
Immunoglobulin heavy chain locus chromosomal translocations in B-cell precursor acute lymphoblastic leukemia: Rare clinical curios or potent genetic drivers?
-
Dyer MJ, Akasaka T, Capasso M, et al: Immunoglobulin heavy chain locus chromosomal translocations in B-cell precursor acute lymphoblastic leukemia: Rare clinical curios or potent genetic drivers? Blood 115:1490-1499, 2010
-
(2010)
Blood
, vol.115
, pp. 1490-1499
-
-
Dyer, M.J.1
Akasaka, T.2
Capasso, M.3
-
15
-
-
34147224008
-
Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia
-
Mullighan CG, Goorha S, Radtke I, et al: Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia. Nature 446:758-764, 2007
-
(2007)
Nature
, vol.446
, pp. 758-764
-
-
Mullighan, C.G.1
Goorha, S.2
Radtke, I.3
-
16
-
-
34249668665
-
Genome complexity in acute lymphoblastic leukemia is revealed by array-based comparative genomic hybridization
-
Strefford JC, Worley H, Barber K, et al: Genome complexity in acute lymphoblastic leukemia is revealed by array-based comparative genomic hybridization. Oncogene 26:4306-4318, 2007
-
(2007)
Oncogene
, vol.26
, pp. 4306-4318
-
-
Strefford, J.C.1
Worley, H.2
Barber, K.3
-
17
-
-
38349177862
-
Molecular allelokaryotyping of pediatric acute lymphoblastic leukemias by high-resolution single nucleotide polymorphism oligonucleotide genomic microarray
-
Kawamata N, Ogawa S, Zimmermann M, et al: Molecular allelokaryotyping of pediatric acute lymphoblastic leukemias by high-resolution single nucleotide polymorphism oligonucleotide genomic microarray. Blood 111:776-784, 2008
-
(2008)
Blood
, vol.111
, pp. 776-784
-
-
Kawamata, N.1
Ogawa, S.2
Zimmermann, M.3
-
18
-
-
58749109707
-
Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia
-
Mullighan CG, Su X, Zhang J, et al: Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia. N Engl J Med 360:470-480, 2009
-
(2009)
N Engl J Med
, vol.360
, pp. 470-480
-
-
Mullighan, C.G.1
Su, X.2
Zhang, J.3
-
19
-
-
43049139905
-
BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros
-
Mullighan CG, Miller CB, Radtke I, et al: BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros. Nature 453:110-114, 2008
-
(2008)
Nature
, vol.453
, pp. 110-114
-
-
Mullighan, C.G.1
Miller, C.B.2
Radtke, I.3
-
20
-
-
79951845044
-
Demographic, clinical, and outcome features of children with acute lymphoblastic leukemia and a CRLF2 deregulation: Results from the MRC ALL97 clinical trial
-
Ensor HM, Schwab C, Russell LJ, et al: Demographic, clinical, and outcome features of children with acute lymphoblastic leukemia and a CRLF2 deregulation: Results from the MRC ALL97 clinical trial. Blood 117:2129-2136, 2011
-
(2011)
Blood
, vol.117
, pp. 2129-2136
-
-
Ensor, H.M.1
Schwab, C.2
Russell, L.J.3
-
21
-
-
77954500629
-
Presence of the P2RY8-CRLF2 rearrangement is associated with a poor prognosis in non-high-risk precursor B-cell acute lymphoblastic leukemia in children treated according to the ALL-BFM 2000 protocol
-
Cario G, Zimmermann M, Romey R, et al: Presence of the P2RY8-CRLF2 rearrangement is associated with a poor prognosis in non-high-risk precursor B-cell acute lymphoblastic leukemia in children treated according to the ALL-BFM 2000 protocol. Blood 115:5393-5397, 2010
-
(2010)
Blood
, vol.115
, pp. 5393-5397
-
-
Cario, G.1
Zimmermann, M.2
Romey, R.3
-
22
-
-
77954516863
-
Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia
-
Harvey RC, Mullighan CG, Chen IM, et al: Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia. Blood 115:5312-5321, 2010
-
(2010)
Blood
, vol.115
, pp. 5312-5321
-
-
Harvey, R.C.1
Mullighan, C.G.2
Chen, I.M.3
-
23
-
-
77954659221
-
IKZF1 deletions predict relapse in uniformly treated pediatric precursor B-ALL
-
Kuiper RP, Waanders E, van der Velden VH, et al: IKZF1 deletions predict relapse in uniformly treated pediatric precursor B-ALL. Leukemia 24:1258-1264, 2010
-
(2010)
Leukemia
, vol.24
, pp. 1258-1264
-
-
Kuiper, R.P.1
Waanders, E.2
Van Der Velden, V.H.3
-
24
-
-
41349100708
-
In adults with standard-risk acute lymphoblastic leukemia, the greatest benefit is achieved from a matched sibling allogeneic transplantation in first complete remission, and an autologous transplantation is less effective than conventional consolidation/maintenance chemotherapy in all patients: Final results of the International ALL Trial (MRC UKALL XII/ECOG E2993)
-
Goldstone AH, Richards SM, Lazarus HM, et al: In adults with standard-risk acute lymphoblastic leukemia, the greatest benefit is achieved from a matched sibling allogeneic transplantation in first complete remission, and an autologous transplantation is less effective than conventional consolidation/maintenance chemotherapy in all patients: Final results of the International ALL Trial (MRC UKALL XII/ECOG E2993). Blood 111:1827-1833, 2008
-
(2008)
Blood
, vol.111
, pp. 1827-1833
-
-
Goldstone, A.H.1
Richards, S.M.2
Lazarus, H.M.3
-
25
-
-
79551707478
-
Evaluation of multiplex ligation-dependent probe amplification as a method for the detection of copy number abnormalities in B-cell precursor acute lymphoblastic leukemia
-
Schwab CJ, Jones LR, Morrison H, et al: Evaluation of multiplex ligation-dependent probe amplification as a method for the detection of copy number abnormalities in B-cell precursor acute lymphoblastic leukemia. Genes Chromosomes Cancer 49:1104-1113, 2010
-
(2010)
Genes Chromosomes Cancer
, vol.49
, pp. 1104-1113
-
-
Schwab, C.J.1
Jones, L.R.2
Morrison, H.3
-
26
-
-
70449647008
-
Proportional hazards tests and diagnostics based on weighted residuals
-
Grambsch PM, Therneau TM: Proportional hazards tests and diagnostics based on weighted residuals. Biometrika 81:515-526, 1994
-
(1994)
Biometrika
, vol.81
, pp. 515-526
-
-
Grambsch, P.M.1
Therneau, T.M.2
-
27
-
-
84859216119
-
Outcome of 1,229 adult Philadelphia chromosome negative B acute lymphoblastic leukemia (B-ALL) patients (pts) from the International UKALLXII/E2993 Trial: No difference in results between B cell immunophenotypic subgroups
-
abstr 524
-
Litzow MR, Buck G, Dewald G, et al: Outcome of 1,229 adult Philadelphia chromosome negative B acute lymphoblastic leukemia (B-ALL) patients (pts) from the International UKALLXII/E2993 Trial: No difference in results between B cell immunophenotypic subgroups. Blood 116:232, 2010 (abstr 524)
-
(2010)
Blood
, vol.116
, pp. 232
-
-
Litzow, M.R.1
Buck, G.2
Dewald, G.3
-
28
-
-
55749102434
-
Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: Implications for a new mechanism of resistance
-
Iacobucci I, Lonetti A, Messa F, et al: Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: Implications for a new mechanism of resistance. Blood 112:3847-3855, 2008
-
(2008)
Blood
, vol.112
, pp. 3847-3855
-
-
Iacobucci, I.1
Lonetti, A.2
Messa, F.3
-
29
-
-
70450255241
-
PAX5 mutations occur frequently in adult B-cell progenitor acute lymphoblastic leukemia and PAX5 haploinsufficiency is associated with BCR-ABL1 and TCF3-PBX1 fusion genes: A GRAALL study
-
Familiades J, Bousquet M, Lafage-Pochitaloff M, et al: PAX5 mutations occur frequently in adult B-cell progenitor acute lymphoblastic leukemia and PAX5 haploinsufficiency is associated with BCR-ABL1 and TCF3-PBX1 fusion genes: A GRAALL study. Leukemia 23:1989-1998, 2009
-
(2009)
Leukemia
, vol.23
, pp. 1989-1998
-
-
Familiades, J.1
Bousquet, M.2
Lafage-Pochitaloff, M.3
-
30
-
-
28444490353
-
Induction therapy for adults with acute lymphoblastic leukemia: Results of more than 1500 patients from the international ALL trial: MRC UKALL XII/ECOG E2993
-
Rowe JM, Buck G, Burnett AK, et al: Induction therapy for adults with acute lymphoblastic leukemia: Results of more than 1500 patients from the international ALL trial: MRC UKALL XII/ECOG E2993. Blood 106:3760-3767, 2005
-
(2005)
Blood
, vol.106
, pp. 3760-3767
-
-
Rowe, J.M.1
Buck, G.2
Burnett, A.K.3
-
31
-
-
76249096219
-
Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia
-
Yoda A, Yoda Y, Chiaretti S, et al: Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia. Proc Natl Acad Sci U S A 107:252-257, 2010
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 252-257
-
-
Yoda, A.1
Yoda, Y.2
Chiaretti, S.3
-
32
-
-
79751538993
-
Integrated use of minimal residual disease classification and IKZF1 alteration status accurately predicts79%of relapses in pediatric acute lymphoblastic leukemia
-
Waanders E, van der Velden VH, van der Schoot CE, et al: Integrated use of minimal residual disease classification and IKZF1 alteration status accurately predicts79%of relapses in pediatric acute lymphoblastic leukemia. Leukemia 25:254-258, 2011
-
(2011)
Leukemia
, vol.25
, pp. 254-258
-
-
Waanders, E.1
Van Der Velden, V.H.2
Van Der Schoot, C.E.3
-
33
-
-
70449719091
-
IKZF1 (Ikaros) deletions in BCR-ABL1-positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: A GIMEMA AL WP report
-
Martinelli G, Iacobucci I, Storlazzi CT, et al: IKZF1 (Ikaros) deletions in BCR-ABL1-positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: A GIMEMA AL WP report. J Clin Oncol 27:5202-5207, 2009
-
(2009)
J Clin Oncol
, vol.27
, pp. 5202-5207
-
-
Martinelli, G.1
Iacobucci, I.2
Storlazzi, C.T.3
-
34
-
-
44349174780
-
Microdeletions are a general feature of adult and adolescent acute lymphoblastic leukemia: Unexpected similarities with pediatric disease
-
Paulsson K, Cazier JB, Macdougall F, et al: Microdeletions are a general feature of adult and adolescent acute lymphoblastic leukemia: Unexpected similarities with pediatric disease. Proc Natl Acad Sci U S A 105:6708-6713, 2008
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 6708-6713
-
-
Paulsson, K.1
Cazier, J.B.2
Macdougall, F.3
-
35
-
-
77957796750
-
The PAX5 gene is frequently rearranged in BCR-ABL1-positive acute lymphoblastic leukemia but is not associated with outcome: A report on behalf of the GIMEMA Acute Leukemia Working Party
-
Iacobucci I, Lonetti A, Paoloni F, et al: The PAX5 gene is frequently rearranged in BCR-ABL1-positive acute lymphoblastic leukemia but is not associated with outcome: A report on behalf of the GIMEMA Acute Leukemia Working Party. Haematologica 95:1683-1690, 2010
-
(2010)
Haematologica
, vol.95
, pp. 1683-1690
-
-
Iacobucci, I.1
Lonetti, A.2
Paoloni, F.3
-
36
-
-
77956798455
-
Genomic profiling of adult acute lymphoblastic leukemia by single nucleotide polymorphism oligonucleotide microarray and comparison to pediatric acute lymphoblastic leukemia
-
Okamoto R, Ogawa S, Nowak D, et al: Genomic profiling of adult acute lymphoblastic leukemia by single nucleotide polymorphism oligonucleotide microarray and comparison to pediatric acute lymphoblastic leukemia. Haematologica 95:1481-1488, 2010
-
(2010)
Haematologica
, vol.95
, pp. 1481-1488
-
-
Okamoto, R.1
Ogawa, S.2
Nowak, D.3
-
37
-
-
55549115330
-
An investigation into whether deletions in 9p reflect prognosis in adult precursor B-cell acute lymphoblastic leukemia: A multi-center study of 381 patients
-
Nahi H, Hägglund H, Ahlgren T, et al: An investigation into whether deletions in 9p reflect prognosis in adult precursor B-cell acute lymphoblastic leukemia: A multi-center study of 381 patients. Haematologica 93:1734-1738, 2008
-
(2008)
Haematologica
, vol.93
, pp. 1734-1738
-
-
Nahi, H.1
Hägglund, H.2
Ahlgren, T.3
-
38
-
-
70349876858
-
Homozygous deletion of CDKN2A (p16, p14) and CDKN2B (p15) genes is a poor prognostic factor in adult but not in childhood B-lineage acute lymphoblastic leukemia: A comparative deletion and hypermethylation study
-
Kim M, Yim SH, Cho NS, et al: Homozygous deletion of CDKN2A (p16, p14) and CDKN2B (p15) genes is a poor prognostic factor in adult but not in childhood B-lineage acute lymphoblastic leukemia: A comparative deletion and hypermethylation study. Cancer Genet Cytogenet 195:59-65, 2009
-
(2009)
Cancer Genet Cytogenet
, vol.195
, pp. 59-65
-
-
Kim, M.1
Yim, S.H.2
Cho, N.S.3
-
39
-
-
43049161332
-
CDKN2A deletions in acute lymphoblastic leukemia of adolescents and young adults: An array CGH study
-
Usvasalo A, Savola S, Räty R, et al: CDKN2A deletions in acute lymphoblastic leukemia of adolescents and young adults: An array CGH study. Leuk Res 32:1228-1235, 2008
-
(2008)
Leuk Res
, vol.32
, pp. 1228-1235
-
-
Usvasalo, A.1
Savola, S.2
Räty, R.3
-
40
-
-
72249121442
-
Minimal residual disease is a significant predictor of treatment failure in non T-lineage adult acute lymphoblastic leukaemia: Final results of the international trial UKALL XII/ECOG2993
-
Patel B, Rai L, Buck G, et al: Minimal residual disease is a significant predictor of treatment failure in non T-lineage adult acute lymphoblastic leukaemia: Final results of the international trial UKALL XII/ECOG2993. Br J Haematol 148:80-89, 2010
-
(2010)
Br J Haematol
, vol.148
, pp. 80-89
-
-
Patel, B.1
Rai, L.2
Buck, G.3
-
41
-
-
61849122810
-
Improvement in survival in younger patients with acute lymphoblastic leukemia from the 1980s to the early 21st century
-
Pulte D, Gondos A, Brenner H: Improvement in survival in younger patients with acute lymphoblastic leukemia from the 1980s to the early 21st century. Blood 113:1408-1411, 2009
-
(2009)
Blood
, vol.113
, pp. 1408-1411
-
-
Pulte, D.1
Gondos, A.2
Brenner, H.3
-
42
-
-
58149095544
-
Cytogenetics of paediatric and adolescent acute lymphoblastic leukaemia
-
Harrison CJ: Cytogenetics of paediatric and adolescent acute lymphoblastic leukaemia. Br J Haematol 144:147-156, 2009
-
(2009)
Br J Haematol
, vol.144
, pp. 147-156
-
-
Harrison, C.J.1
|