메뉴 건너뛰기




Volumn 30, Issue 25, 2012, Pages 3100-3108

IGH@ translocations, CRLF2 deregulation, and microdeletions in adolescents and adults with acute lymphoblastic leukemia

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR ETV6; TRANSCRIPTION FACTOR PAX5;

EID: 84865745212     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2011.40.3907     Document Type: Article
Times cited : (111)

References (42)
  • 1
    • 34147135183 scopus 로고    scopus 로고
    • Karyotype is an independent prognostic factor in adult acute lymphoblastic leukemia (ALL): Analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) UKALLXII/Eastern Cooperative Oncology Group (ECOG) 2993 Trial
    • Moorman AV, Harrison CJ, Buck GA, et al: Karyotype is an independent prognostic factor in adult acute lymphoblastic leukemia (ALL): Analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) UKALLXII/Eastern Cooperative Oncology Group (ECOG) 2993 Trial. Blood 109:3189-3197, 2007
    • (2007) Blood , vol.109 , pp. 3189-3197
    • Moorman, A.V.1    Harrison, C.J.2    Buck, G.A.3
  • 2
    • 41949083910 scopus 로고    scopus 로고
    • Impact of cytogenetics on the outcome of adult acute lymphoblastic leukemia: Results of Southwest Oncology Group 9400 study
    • Pullarkat V, Slovak ML, Kopecky KJ, et al: Impact of cytogenetics on the outcome of adult acute lymphoblastic leukemia: Results of Southwest Oncology Group 9400 study. Blood 111:2563-2572, 2008
    • (2008) Blood , vol.111 , pp. 2563-2572
    • Pullarkat, V.1    Slovak, M.L.2    Kopecky, K.J.3
  • 3
    • 79952095577 scopus 로고    scopus 로고
    • Modern therapy of acute lymphoblastic leukemia
    • Bassan R, Hoelzer D: Modern therapy of acute lymphoblastic leukemia. J Clin Oncol 29:532-543, 2011
    • (2011) J Clin Oncol , vol.29 , pp. 532-543
    • Bassan, R.1    Hoelzer, D.2
  • 4
    • 58649087583 scopus 로고    scopus 로고
    • Optimal management of adults with ALL
    • Rowe JM: Optimal management of adults with ALL. Br J Haematol 144:468-483, 2009
    • (2009) Br J Haematol , vol.144 , pp. 468-483
    • Rowe, J.M.1
  • 5
    • 62549141516 scopus 로고    scopus 로고
    • A novel translocation, t(14;19)(q32;p13), involving IGH@ and the cytokine receptor for erythropoietin
    • Russell LJ, De Castro DG, Griffiths M, et al: A novel translocation, t(14;19)(q32;p13), involving IGH@ and the cytokine receptor for erythropoietin. Leukemia 23:614-617, 2009
    • (2009) Leukemia , vol.23 , pp. 614-617
    • Russell, L.J.1    De Castro, D.G.2    Griffiths, M.3
  • 6
    • 70350519430 scopus 로고    scopus 로고
    • Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia
    • Russell LJ, Capasso M, Vater I, et al: Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia. Blood 114:2688-2698, 2009
    • (2009) Blood , vol.114 , pp. 2688-2698
    • Russell, L.J.1    Capasso, M.2    Vater, I.3
  • 7
    • 38049126095 scopus 로고    scopus 로고
    • t(6;14)(p22;q32): A new recurrent IGH@ translocation involving ID4 in B-cell precursor acute lymphoblastic leukemia (BCP-ALL)
    • Russell LJ, Akasaka T, Majid A, et al: t(6;14)(p22;q32): A new recurrent IGH@ translocation involving ID4 in B-cell precursor acute lymphoblastic leukemia (BCP-ALL). Blood 111:387-391, 2008
    • (2008) Blood , vol.111 , pp. 387-391
    • Russell, L.J.1    Akasaka, T.2    Majid, A.3
  • 8
    • 34147161800 scopus 로고    scopus 로고
    • Five members of the CEBP transcription factor family are targeted by recurrent IGH translocations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL)
    • Akasaka T, Balasas T, Russell LJ, et al: Five members of the CEBP transcription factor family are targeted by recurrent IGH translocations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL). Blood 109:3451-3461, 2007
    • (2007) Blood , vol.109 , pp. 3451-3461
    • Akasaka, T.1    Balasas, T.2    Russell, L.J.3
  • 9
    • 33751196596 scopus 로고    scopus 로고
    • Overexpression of CEBPA resulting from the translocation t(14;19)(q32;q13) of human precursor B acute lymphoblastic leukemia
    • Chapiro E, Russell L, Radford-Weiss I, et al: Overexpression of CEBPA resulting from the translocation t(14;19)(q32;q13) of human precursor B acute lymphoblastic leukemia. Blood 108:3560-3563, 2006
    • (2006) Blood , vol.108 , pp. 3560-3563
    • Chapiro, E.1    Russell, L.2    Radford-Weiss, I.3
  • 10
    • 77954658856 scopus 로고    scopus 로고
    • A new recurrent translocation t(11;14)(q24;q32) involving IGH@ and miR-125b-1 in B-cell progenitor acute lymphoblastic leukemia
    • Chapiro E, Russell LJ, Struski S, et al: A new recurrent translocation t(11;14)(q24;q32) involving IGH@ and miR-125b-1 in B-cell progenitor acute lymphoblastic leukemia. Leukemia 24:1362-1364, 2010
    • (2010) Leukemia , vol.24 , pp. 1362-1364
    • Chapiro, E.1    Russell, L.J.2    Struski, S.3
  • 11
    • 77949425065 scopus 로고    scopus 로고
    • Activating mutation in the TSLPR gene in B-cell precursor lymphoblastic leukemia
    • Chapiro E, Russell L, Lainey E, et al: Activating mutation in the TSLPR gene in B-cell precursor lymphoblastic leukemia. Leukemia 24:642-645, 2010
    • (2010) Leukemia , vol.24 , pp. 642-645
    • Chapiro, E.1    Russell, L.2    Lainey, E.3
  • 12
    • 77649214639 scopus 로고    scopus 로고
    • Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: A report from the International BFM Study Group
    • Hertzberg L, Vendramini E, Ganmore I, et al: Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: A report from the International BFM Study Group. Blood 115:1006-1017, 2010
    • (2010) Blood , vol.115 , pp. 1006-1017
    • Hertzberg, L.1    Vendramini, E.2    Ganmore, I.3
  • 13
    • 70350680415 scopus 로고    scopus 로고
    • Rearrangement of CRLF2 in B-progenitorand Down syndrome-associated acute lymphoblastic leukemia
    • Mullighan CG, Collins-Underwood JR, Phillips LA, et al: Rearrangement of CRLF2 in B-progenitorand Down syndrome-associated acute lymphoblastic leukemia. Nat Genet 41:1243-1246, 2009
    • (2009) Nat Genet , vol.41 , pp. 1243-1246
    • Mullighan, C.G.1    Collins-Underwood, J.R.2    Phillips, L.A.3
  • 14
    • 77949910163 scopus 로고    scopus 로고
    • Immunoglobulin heavy chain locus chromosomal translocations in B-cell precursor acute lymphoblastic leukemia: Rare clinical curios or potent genetic drivers?
    • Dyer MJ, Akasaka T, Capasso M, et al: Immunoglobulin heavy chain locus chromosomal translocations in B-cell precursor acute lymphoblastic leukemia: Rare clinical curios or potent genetic drivers? Blood 115:1490-1499, 2010
    • (2010) Blood , vol.115 , pp. 1490-1499
    • Dyer, M.J.1    Akasaka, T.2    Capasso, M.3
  • 15
    • 34147224008 scopus 로고    scopus 로고
    • Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia
    • Mullighan CG, Goorha S, Radtke I, et al: Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia. Nature 446:758-764, 2007
    • (2007) Nature , vol.446 , pp. 758-764
    • Mullighan, C.G.1    Goorha, S.2    Radtke, I.3
  • 16
    • 34249668665 scopus 로고    scopus 로고
    • Genome complexity in acute lymphoblastic leukemia is revealed by array-based comparative genomic hybridization
    • Strefford JC, Worley H, Barber K, et al: Genome complexity in acute lymphoblastic leukemia is revealed by array-based comparative genomic hybridization. Oncogene 26:4306-4318, 2007
    • (2007) Oncogene , vol.26 , pp. 4306-4318
    • Strefford, J.C.1    Worley, H.2    Barber, K.3
  • 17
    • 38349177862 scopus 로고    scopus 로고
    • Molecular allelokaryotyping of pediatric acute lymphoblastic leukemias by high-resolution single nucleotide polymorphism oligonucleotide genomic microarray
    • Kawamata N, Ogawa S, Zimmermann M, et al: Molecular allelokaryotyping of pediatric acute lymphoblastic leukemias by high-resolution single nucleotide polymorphism oligonucleotide genomic microarray. Blood 111:776-784, 2008
    • (2008) Blood , vol.111 , pp. 776-784
    • Kawamata, N.1    Ogawa, S.2    Zimmermann, M.3
  • 18
    • 58749109707 scopus 로고    scopus 로고
    • Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia
    • Mullighan CG, Su X, Zhang J, et al: Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia. N Engl J Med 360:470-480, 2009
    • (2009) N Engl J Med , vol.360 , pp. 470-480
    • Mullighan, C.G.1    Su, X.2    Zhang, J.3
  • 19
    • 43049139905 scopus 로고    scopus 로고
    • BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros
    • Mullighan CG, Miller CB, Radtke I, et al: BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros. Nature 453:110-114, 2008
    • (2008) Nature , vol.453 , pp. 110-114
    • Mullighan, C.G.1    Miller, C.B.2    Radtke, I.3
  • 20
    • 79951845044 scopus 로고    scopus 로고
    • Demographic, clinical, and outcome features of children with acute lymphoblastic leukemia and a CRLF2 deregulation: Results from the MRC ALL97 clinical trial
    • Ensor HM, Schwab C, Russell LJ, et al: Demographic, clinical, and outcome features of children with acute lymphoblastic leukemia and a CRLF2 deregulation: Results from the MRC ALL97 clinical trial. Blood 117:2129-2136, 2011
    • (2011) Blood , vol.117 , pp. 2129-2136
    • Ensor, H.M.1    Schwab, C.2    Russell, L.J.3
  • 21
    • 77954500629 scopus 로고    scopus 로고
    • Presence of the P2RY8-CRLF2 rearrangement is associated with a poor prognosis in non-high-risk precursor B-cell acute lymphoblastic leukemia in children treated according to the ALL-BFM 2000 protocol
    • Cario G, Zimmermann M, Romey R, et al: Presence of the P2RY8-CRLF2 rearrangement is associated with a poor prognosis in non-high-risk precursor B-cell acute lymphoblastic leukemia in children treated according to the ALL-BFM 2000 protocol. Blood 115:5393-5397, 2010
    • (2010) Blood , vol.115 , pp. 5393-5397
    • Cario, G.1    Zimmermann, M.2    Romey, R.3
  • 22
    • 77954516863 scopus 로고    scopus 로고
    • Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia
    • Harvey RC, Mullighan CG, Chen IM, et al: Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia. Blood 115:5312-5321, 2010
    • (2010) Blood , vol.115 , pp. 5312-5321
    • Harvey, R.C.1    Mullighan, C.G.2    Chen, I.M.3
  • 23
    • 77954659221 scopus 로고    scopus 로고
    • IKZF1 deletions predict relapse in uniformly treated pediatric precursor B-ALL
    • Kuiper RP, Waanders E, van der Velden VH, et al: IKZF1 deletions predict relapse in uniformly treated pediatric precursor B-ALL. Leukemia 24:1258-1264, 2010
    • (2010) Leukemia , vol.24 , pp. 1258-1264
    • Kuiper, R.P.1    Waanders, E.2    Van Der Velden, V.H.3
  • 24
    • 41349100708 scopus 로고    scopus 로고
    • In adults with standard-risk acute lymphoblastic leukemia, the greatest benefit is achieved from a matched sibling allogeneic transplantation in first complete remission, and an autologous transplantation is less effective than conventional consolidation/maintenance chemotherapy in all patients: Final results of the International ALL Trial (MRC UKALL XII/ECOG E2993)
    • Goldstone AH, Richards SM, Lazarus HM, et al: In adults with standard-risk acute lymphoblastic leukemia, the greatest benefit is achieved from a matched sibling allogeneic transplantation in first complete remission, and an autologous transplantation is less effective than conventional consolidation/maintenance chemotherapy in all patients: Final results of the International ALL Trial (MRC UKALL XII/ECOG E2993). Blood 111:1827-1833, 2008
    • (2008) Blood , vol.111 , pp. 1827-1833
    • Goldstone, A.H.1    Richards, S.M.2    Lazarus, H.M.3
  • 25
    • 79551707478 scopus 로고    scopus 로고
    • Evaluation of multiplex ligation-dependent probe amplification as a method for the detection of copy number abnormalities in B-cell precursor acute lymphoblastic leukemia
    • Schwab CJ, Jones LR, Morrison H, et al: Evaluation of multiplex ligation-dependent probe amplification as a method for the detection of copy number abnormalities in B-cell precursor acute lymphoblastic leukemia. Genes Chromosomes Cancer 49:1104-1113, 2010
    • (2010) Genes Chromosomes Cancer , vol.49 , pp. 1104-1113
    • Schwab, C.J.1    Jones, L.R.2    Morrison, H.3
  • 26
    • 70449647008 scopus 로고
    • Proportional hazards tests and diagnostics based on weighted residuals
    • Grambsch PM, Therneau TM: Proportional hazards tests and diagnostics based on weighted residuals. Biometrika 81:515-526, 1994
    • (1994) Biometrika , vol.81 , pp. 515-526
    • Grambsch, P.M.1    Therneau, T.M.2
  • 27
    • 84859216119 scopus 로고    scopus 로고
    • Outcome of 1,229 adult Philadelphia chromosome negative B acute lymphoblastic leukemia (B-ALL) patients (pts) from the International UKALLXII/E2993 Trial: No difference in results between B cell immunophenotypic subgroups
    • abstr 524
    • Litzow MR, Buck G, Dewald G, et al: Outcome of 1,229 adult Philadelphia chromosome negative B acute lymphoblastic leukemia (B-ALL) patients (pts) from the International UKALLXII/E2993 Trial: No difference in results between B cell immunophenotypic subgroups. Blood 116:232, 2010 (abstr 524)
    • (2010) Blood , vol.116 , pp. 232
    • Litzow, M.R.1    Buck, G.2    Dewald, G.3
  • 28
    • 55749102434 scopus 로고    scopus 로고
    • Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: Implications for a new mechanism of resistance
    • Iacobucci I, Lonetti A, Messa F, et al: Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: Implications for a new mechanism of resistance. Blood 112:3847-3855, 2008
    • (2008) Blood , vol.112 , pp. 3847-3855
    • Iacobucci, I.1    Lonetti, A.2    Messa, F.3
  • 29
    • 70450255241 scopus 로고    scopus 로고
    • PAX5 mutations occur frequently in adult B-cell progenitor acute lymphoblastic leukemia and PAX5 haploinsufficiency is associated with BCR-ABL1 and TCF3-PBX1 fusion genes: A GRAALL study
    • Familiades J, Bousquet M, Lafage-Pochitaloff M, et al: PAX5 mutations occur frequently in adult B-cell progenitor acute lymphoblastic leukemia and PAX5 haploinsufficiency is associated with BCR-ABL1 and TCF3-PBX1 fusion genes: A GRAALL study. Leukemia 23:1989-1998, 2009
    • (2009) Leukemia , vol.23 , pp. 1989-1998
    • Familiades, J.1    Bousquet, M.2    Lafage-Pochitaloff, M.3
  • 30
    • 28444490353 scopus 로고    scopus 로고
    • Induction therapy for adults with acute lymphoblastic leukemia: Results of more than 1500 patients from the international ALL trial: MRC UKALL XII/ECOG E2993
    • Rowe JM, Buck G, Burnett AK, et al: Induction therapy for adults with acute lymphoblastic leukemia: Results of more than 1500 patients from the international ALL trial: MRC UKALL XII/ECOG E2993. Blood 106:3760-3767, 2005
    • (2005) Blood , vol.106 , pp. 3760-3767
    • Rowe, J.M.1    Buck, G.2    Burnett, A.K.3
  • 31
    • 76249096219 scopus 로고    scopus 로고
    • Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia
    • Yoda A, Yoda Y, Chiaretti S, et al: Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia. Proc Natl Acad Sci U S A 107:252-257, 2010
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 252-257
    • Yoda, A.1    Yoda, Y.2    Chiaretti, S.3
  • 32
    • 79751538993 scopus 로고    scopus 로고
    • Integrated use of minimal residual disease classification and IKZF1 alteration status accurately predicts79%of relapses in pediatric acute lymphoblastic leukemia
    • Waanders E, van der Velden VH, van der Schoot CE, et al: Integrated use of minimal residual disease classification and IKZF1 alteration status accurately predicts79%of relapses in pediatric acute lymphoblastic leukemia. Leukemia 25:254-258, 2011
    • (2011) Leukemia , vol.25 , pp. 254-258
    • Waanders, E.1    Van Der Velden, V.H.2    Van Der Schoot, C.E.3
  • 33
    • 70449719091 scopus 로고    scopus 로고
    • IKZF1 (Ikaros) deletions in BCR-ABL1-positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: A GIMEMA AL WP report
    • Martinelli G, Iacobucci I, Storlazzi CT, et al: IKZF1 (Ikaros) deletions in BCR-ABL1-positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: A GIMEMA AL WP report. J Clin Oncol 27:5202-5207, 2009
    • (2009) J Clin Oncol , vol.27 , pp. 5202-5207
    • Martinelli, G.1    Iacobucci, I.2    Storlazzi, C.T.3
  • 34
    • 44349174780 scopus 로고    scopus 로고
    • Microdeletions are a general feature of adult and adolescent acute lymphoblastic leukemia: Unexpected similarities with pediatric disease
    • Paulsson K, Cazier JB, Macdougall F, et al: Microdeletions are a general feature of adult and adolescent acute lymphoblastic leukemia: Unexpected similarities with pediatric disease. Proc Natl Acad Sci U S A 105:6708-6713, 2008
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 6708-6713
    • Paulsson, K.1    Cazier, J.B.2    Macdougall, F.3
  • 35
    • 77957796750 scopus 로고    scopus 로고
    • The PAX5 gene is frequently rearranged in BCR-ABL1-positive acute lymphoblastic leukemia but is not associated with outcome: A report on behalf of the GIMEMA Acute Leukemia Working Party
    • Iacobucci I, Lonetti A, Paoloni F, et al: The PAX5 gene is frequently rearranged in BCR-ABL1-positive acute lymphoblastic leukemia but is not associated with outcome: A report on behalf of the GIMEMA Acute Leukemia Working Party. Haematologica 95:1683-1690, 2010
    • (2010) Haematologica , vol.95 , pp. 1683-1690
    • Iacobucci, I.1    Lonetti, A.2    Paoloni, F.3
  • 36
    • 77956798455 scopus 로고    scopus 로고
    • Genomic profiling of adult acute lymphoblastic leukemia by single nucleotide polymorphism oligonucleotide microarray and comparison to pediatric acute lymphoblastic leukemia
    • Okamoto R, Ogawa S, Nowak D, et al: Genomic profiling of adult acute lymphoblastic leukemia by single nucleotide polymorphism oligonucleotide microarray and comparison to pediatric acute lymphoblastic leukemia. Haematologica 95:1481-1488, 2010
    • (2010) Haematologica , vol.95 , pp. 1481-1488
    • Okamoto, R.1    Ogawa, S.2    Nowak, D.3
  • 37
    • 55549115330 scopus 로고    scopus 로고
    • An investigation into whether deletions in 9p reflect prognosis in adult precursor B-cell acute lymphoblastic leukemia: A multi-center study of 381 patients
    • Nahi H, Hägglund H, Ahlgren T, et al: An investigation into whether deletions in 9p reflect prognosis in adult precursor B-cell acute lymphoblastic leukemia: A multi-center study of 381 patients. Haematologica 93:1734-1738, 2008
    • (2008) Haematologica , vol.93 , pp. 1734-1738
    • Nahi, H.1    Hägglund, H.2    Ahlgren, T.3
  • 38
    • 70349876858 scopus 로고    scopus 로고
    • Homozygous deletion of CDKN2A (p16, p14) and CDKN2B (p15) genes is a poor prognostic factor in adult but not in childhood B-lineage acute lymphoblastic leukemia: A comparative deletion and hypermethylation study
    • Kim M, Yim SH, Cho NS, et al: Homozygous deletion of CDKN2A (p16, p14) and CDKN2B (p15) genes is a poor prognostic factor in adult but not in childhood B-lineage acute lymphoblastic leukemia: A comparative deletion and hypermethylation study. Cancer Genet Cytogenet 195:59-65, 2009
    • (2009) Cancer Genet Cytogenet , vol.195 , pp. 59-65
    • Kim, M.1    Yim, S.H.2    Cho, N.S.3
  • 39
    • 43049161332 scopus 로고    scopus 로고
    • CDKN2A deletions in acute lymphoblastic leukemia of adolescents and young adults: An array CGH study
    • Usvasalo A, Savola S, Räty R, et al: CDKN2A deletions in acute lymphoblastic leukemia of adolescents and young adults: An array CGH study. Leuk Res 32:1228-1235, 2008
    • (2008) Leuk Res , vol.32 , pp. 1228-1235
    • Usvasalo, A.1    Savola, S.2    Räty, R.3
  • 40
    • 72249121442 scopus 로고    scopus 로고
    • Minimal residual disease is a significant predictor of treatment failure in non T-lineage adult acute lymphoblastic leukaemia: Final results of the international trial UKALL XII/ECOG2993
    • Patel B, Rai L, Buck G, et al: Minimal residual disease is a significant predictor of treatment failure in non T-lineage adult acute lymphoblastic leukaemia: Final results of the international trial UKALL XII/ECOG2993. Br J Haematol 148:80-89, 2010
    • (2010) Br J Haematol , vol.148 , pp. 80-89
    • Patel, B.1    Rai, L.2    Buck, G.3
  • 41
    • 61849122810 scopus 로고    scopus 로고
    • Improvement in survival in younger patients with acute lymphoblastic leukemia from the 1980s to the early 21st century
    • Pulte D, Gondos A, Brenner H: Improvement in survival in younger patients with acute lymphoblastic leukemia from the 1980s to the early 21st century. Blood 113:1408-1411, 2009
    • (2009) Blood , vol.113 , pp. 1408-1411
    • Pulte, D.1    Gondos, A.2    Brenner, H.3
  • 42
    • 58149095544 scopus 로고    scopus 로고
    • Cytogenetics of paediatric and adolescent acute lymphoblastic leukaemia
    • Harrison CJ: Cytogenetics of paediatric and adolescent acute lymphoblastic leukaemia. Br J Haematol 144:147-156, 2009
    • (2009) Br J Haematol , vol.144 , pp. 147-156
    • Harrison, C.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.