Autoimmune hepatitis

Digestive Diseases

Volumn 31, Issue 1, 2013, Pages 155-163

  Strassburg, Christian P ^a  

^a UNIVERSITY HOSPITAL BONN   (Germany)

Author keywords

Budesonide; First pass effect; Immunosuppression; Recurrence; Transplantation

Indexed keywords

AMINOTRANSFERASE; AZATHIOPRINE; BUDESONIDE; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; IMMUNOSUPPRESSIVE AGENT; INTERFERON; METHOTREXATE; MYCOPHENOLIC ACID; PREDNISOLONE; PREDNISONE; RITUXIMAB; STEROID; TACROLIMUS; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

ABDOMINAL DISCOMFORT; ACUTE HEPATITIS; ARTHRALGIA; ARTICLE; ASEPTIC NECROSIS; AUTOIMMUNE DISEASE; AUTOIMMUNE HEPATITIS; BONE MARROW SUPPRESSION; CATARACTOGENESIS; CHOLESTATIC HEPATITIS; CHRONIC HEPATITIS; CUSHINGOID SYNDROME; DIABETES MELLITUS; DRUG TREATMENT FAILURE; EARLY DIAGNOSIS; ENZYME ACTIVITY; GRAFT FAILURE; HEMATOLOGIC DISEASE; HUMAN; HYPERTENSION; IMMUNOSUPPRESSIVE TREATMENT; LEUKOPENIA; LIVER BIOPSY; LIVER CIRRHOSIS; LIVER TRANSPLANTATION; LYMPHOCYTOPENIA; MAINTENANCE THERAPY; MENTAL DISEASE; MONOTHERAPY; MULTICENTER STUDY (TOPIC); MYALGIA; NAUSEA; NEPHROTOXICITY; OSTEOPENIA; PERIOPERATIVE PERIOD; PRIORITY JOURNAL; PROGNOSIS; PROSPECTIVE STUDY; RASH; RECURRENT DISEASE; REMISSION; RISK FACTOR; SIDE EFFECT; STEROID THERAPY; TERATOGENICITY; AGE; ALTERNATIVE MEDICINE; CONFERENCE PAPER; RANDOMIZED CONTROLLED TRIAL (TOPIC); TREATMENT CONTRAINDICATION; TREATMENT INDICATION;

AGE DISTRIBUTION; HEPATITIS, AUTOIMMUNE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; LIVER TRANSPLANTATION; RECURRENCE;

EID: 84879590067     PISSN: 02572753     EISSN: 14219875     Source Type: Journal    
DOI: 10.1159/000347211     Document Type: Article

References (57)

1. Kirk AP, Jain S, Pocock S, Thomas HC, Sherlock S: Late results of the Royal Free Hospital prospective controlled trial of prednisolone therapy in hepatitis B surface antigen negative chronic active hepatitis. Gut 1980; 21: 7893.
2. Geall MG, Schoenfield LJ, Summerskill WHJ: Classification and treatment of chronic active liver disease. Gastroenterology 1968; 55: 724-729.
3. Soloway RD, Summerskill WH, Baggenstoss AH, Geall MG, Gitnick GL, Elveback IR, Schoenfield LJ: Clinical, biochemical, and histological remission of severe chronic active liver disease: a controlled study of treatments and early prognosis. Gastroenterology 1972; 63: 820-833.
4. Gregorio GV, Portman B, Reid F, Donaldson PT, Doherty DG, McCartney M, Vergani D, Mieli-Vergani G: Autoimmune hepatitis in childhood: a 20-year experience. Hepatology 1997; 25: 541-547. (Pubitemid 27106430)
5. Homberg JC, Abuaf N, Bernard O, Islam S, Alvarez F, Khalil SH, Poupon R, Darnis F, Levy VG, Grippon P: Chronic active hepatitis associated with antiliver/kidney microsome type 1: a second type of 'autoimmune' hepatitis. Hepatology 1987; 7: 1333-1339. (Pubitemid 18014211)
6. Strassburg CP, Manns MP: Autoimmune hepatitis in the elderly: what is the difference? J Hepatol 2006; 45: 480-482. (Pubitemid 44307390)
7. Manns MP, Strassburg CP: Autoimmune hepatitis: clinical challenges. Gastroenterology 2001; 120: 1502-1517. (Pubitemid 32322325)
8. Czaja AJ, Manns MP: Advances in the diagnosis, pathogenesis, and management of autoimmune hepatitis. Gastroenterology 2010; 139: 58-72.e54.
9. Manns MP, Czaja AJ, Gorham JD, Krawitt EL, Mieli-Vergani G, Vergani D, Vierling JM: Diagnosis and management of autoimmune hepatitis. Hepatology 2010; 51: 2193-2213.
10. Johnson PJ, McFarlane IG, Williams R: Azathioprine for long-term maintenance of remission in autoimmune hepatitis. N Engl J Med 1995; 333: 958-963.
11. Nikias GA, Batts KP, Czaja AJ: The nature and prognostic implications of autoimmune hepatitis with acute presentation. J Hepatol 1994; 21: 866-871. (Pubitemid 24374156)
12. Newton JL, Burt AD, Park JB, Mathew J, Bassendine MF, James OF: Autoimmune hepatitis in older patients. Age Ageing 1997; 26: 441-444. (Pubitemid 28014908)
13. Schramm C, Kanzler S, zum Buschenfelde KH, Galle PR, Lohse AW: Autoimmune hepatitis in the elderly. Am J Gastroenterol 2001; 96: 1587-1591.
14. Czaja AJ, Carpenter HA: Distinctive clinical phenotype and treatment outcome of type 1 autoimmune hepatitis in the elderly. Hepatology 2006; 43: 532-538.
15. Czaja AJ, Carpenter HA, Santrach PJ, Moore SB: Significance of HLA DR4 in type 1 autoimmune hepatitis. Gastroenterology 1993; 105: 1502-1507. (Pubitemid 23315327)
16. Al-Chalabi T, Boccato S, Portmann BC, Mc-Farlane IG, Heneghan MA: Autoimmune hepatitis (AIH) in the elderly: a systematic retrospective analysis of a large group of consecutive patients with definite AIH followed at a tertiary referral centre. J Hepatol 2006; 45: 575-583. (Pubitemid 44307378)
17. Prelog M: Aging of the immune system: a risk factor for autoimmunity? Autoimmun Rev 2006; 5: 136-139. (Pubitemid 43129545)
18. Talor E, Rose NR: Hypothesis: the aging paradox and autoimmune disease. Autoimmunity 1991; 8: 245-249.
19. Thalen A, Brattsand R: Synthesis and anti-inflammatory properties of budesonide, a new non-halogenated glucocorticoid with high local activity. Arzneimittelforschung 1979; 29: 1687-1690.
20. Danielsson A, Prytz H: Oral budesonide for treatment of autoimmune chronic active hepatitis. Aliment Pharmacol Ther 1994; 8: 585-590. (Pubitemid 24381357)
21. Czaja AJ, Lindor KD: Failure of budesonide in a pilot study of treatment-dependent autoimmune hepatitis. Gastroenterology 2000; 119: 1312-1316.
22. Wiegand J, Schuler A, Kanzler S, Lohse A, Beuers U, Kreisel W, Spengler U, Koletzko S, Jansen PL, Hochhaus G, et al: Budesonide in previously untreated autoimmune hepatitis. Liver Int 2005; 25: 927-934. (Pubitemid 41404011)
23. Manns MP, Woynarowski M, Kreisel W, Lurie Y, Rust C, Zuckerman E, Bahr MJ, Gunther R, Hultcrantz RW, Spengler U, et al: Budesonide induces remission more effectively than prednisone in a controlled trial of patients with autoimmune hepatitis. Gastroenterology 2010; 139: 1198-1206.
24. Strassburg CP, Bahr MJ, Becker T, Klempnauer J, Manns MP: Progress in immunosuppression (in German). Chirurg 2008; 79: 149-156.
25. Alvarez F, Ciocca M, Canero-Velasco C, et al: Short-term cyclosporine induces a remission of autoimmune hepatitis in children. J Hepatol 1999; 30: 222-227. (Pubitemid 29071183)
26. Debray D, Maggiore G, Giradet JP, Mallet E, Bernard O: Efficacy of cyclosporin A in children with type 2 autoimmune hepatitis. J Pediatr 1999; 135: 111-114. (Pubitemid 30180574)
27. Fernandez NF, Redeker AG, Vierling JM, Villamil FG, Fong TL: Cyclosporine therapy in patients with steroid resistant autoimmune hepatitis. Am J Gastroenterol 1999; 94: 241-248. (Pubitemid 29063476)
28. Heneghan MA, McFarlane IG: Current and novel immunosuppressive therapy for autoimmune hepatitis. Hepatology 2002; 35: 7-13. (Pubitemid 34032538)
29. Van Thiel DH, Wright H, Carroll P, Abu-Elmagd K, Rodriguez-Rilo H, McMichael J, Irish W, Starzl TE: Tacrolimus: a potential new treatment for autoimmune chronic active hepatitis: results of an open-label preliminary trial. Am J Gastroenterol 1995; 90: 771-776.
30. Aqel BA, Machicao V, Rosser B, Satyanarayana R, Harnois DM, Dickson RC: Efficacy of tacrolimus in the treatment of steroid refractory autoimmune hepatitis. J Clin Gastroenterol 2004; 38: 805-809. (Pubitemid 39274185)
31. Richardson PD, James PD, Ryder SD: Mycophenolate mofetil for maintenance of remission in autoimmune hepatitis in patients resistant to or intolerant of azathioprine. J Hepatol 2000; 33: 371-375. (Pubitemid 30663373)
32. Hennes EM, Oo YH, Schramm C, Denzer U, Buggisch P, Wiegard C, Kanzler S, Schuchmann M, Boecher W, Galle PR, et al: Mycophenolate mofetil as second line therapy in autoimmune hepatitis? Am J Gastroenterol 2008; 103: 3063-3070.
33. Kanzler S, Gerken G, Dienes HP, Meyer zum Buschenfelde K-H, Lohse AW: Cyclophosphamide as alternative immunosuppressive therapy for autoimmune hepatitis-report of three cases. Z Gastroenterol 1996; 35: 571-578. (Pubitemid 27321630)
34. Umekita K, Miyauchi S, Ueno S, Takajo I, Kusumoto K, Hasuike S, Umekita Y, Tanaka H, Nagata K, Nagatomo Y, et al: Improvement of rheumatoid arthritis and autoimmune hepatitis in a patient treated with the tumor necrosis factor inhibitor, etanercept. Intern Med 2011; 50: 1245-1249.
35. Efe C, Purnak T, Ozaslan E: Anti TNF-alpha therapy can be a novel treatment option in patients with autoimmune hepatitis. Aliment Pharmacol Ther 2010; 32: 115, author reply 116-117.
36. Ramos-Casals M, Brito-Zeron P, Soto MJ, Cuadrado MJ, Khamashta MA: Autoimmune diseases induced by TNF-targeted therapies. Best Pract Res Clin Rheumatol 2008; 22: 847-861.
37. Strassburg CP, Becker T, Klempnauer J, Manns MP: Liver transplantation: deciding between need and donor allocation (in German). Internist (Berl) 2004; 45: 1233-1245.
38. Ahmed M, Mutimer D, Hathaway M, Hubscher S, McMaster P, Elias E: Liver transplantation for autoimmune hepatitis: a 12-year experience. Transplant Proc 1997; 29: 496. (Pubitemid 27123503)
39. Neuberger J, Portmann B, Calne R, Williams R: Recurrence of autoimmune chronic active hepatitis following orthotopic liver grafting. Transplantation 1984; 37: 363-365. (Pubitemid 14105426)
40. Prados E, Cuervas-Mons V, De La Mata M, Fraga E, Rimola A, Prieto M, Clemente G, Vicente E, Casanovas T, Fabrega E: Outcome of autoimmune hepatitis after liver transplantation. Transplantation 1998; 66: 1645-1650. (Pubitemid 29034985)
41. Sanchez-Urdazpal L, Czaja AJ, Van Holk B: Prognostic features and role of liver transplantation in severe corticoid-treated autoimmune chronic active hepatitis. Hepatology 1991; 15: 215-221.
42. Tillmann HL, Jackel E, Manns MP: Liver transplantation in autoimmune liver disease-selection of patients. Hepatogastroenterology 1999; 46: 3053-3059.
43. Vogel A, Heinrich E, Bahr MJ, Rifai K, Flemming P, Melter M, Klempnauer J, Nashan B, Manns MP, Strassburg CP: Long-term outcome of liver transplantation for autoimmune hepatitis. Clin Transplant 2004; 18: 62-69. (Pubitemid 38195546)
44. Strassburg CP, Manns MP: Liver transplantation: indications and results (in German). Internist (Berl) 2009; 50: 550-560.
45. Ratziu V, Samuel D, Sebagh M, Farges O, Saliba F, Ichai P, Farahmand H, Gigou M, Feray C, Reynes M, et al: Long-term follow-up after liver transplantation for autoimmune hepatitis: evidence of recurrence of primary disease. J Hepatol 1999; 30: 131-141. (Pubitemid 29023662)
46. Schreuder TC, Hubscher SG, Neuberger J: Autoimmune liver diseases and recurrence after orthotopic liver transplantation: what have we learned so far? Transpl Int 2009; 22: 144-152.
47. Devlin J, Donaldson P, Portman B, et al: Recurrence of autoimmune hepatitis following liver transplantation. Liver Transpl Surg 1995; 1: 162-165.
48. Manns MP, Bahr MJ: Recurrent autoimmune hepatitis after liver transplantation-when non-self becomes self. Hepatology 2000; 32: 868-870.
49. Milkiewicz P, Hubscher SG, Skiba G, Hathaway M, Elias E: Recurrence of autoimmune hepatitis after liver transplantation. Transplantation 1999; 68: 253-256. (Pubitemid 29360286)
50. Wright HL, Bou-Abboud CF, Hassanenstein T, Block GD, Demetris AJ, Starzi TE, Van Thiel DH: Disease recurrence and rejection following liver transplantation for autoimmune chronic active liver disease. Transplantation 1992; 53: 136-139.
51. Gotz G, Neuhaus R, Bechstein WO, Lobeck H, Berg T, Hopf U, Neuhaus P: Recurrence of autoimmune hepatitis after liver transplantation. Transplant Proc 1999; 31: 430-431. (Pubitemid 29127513)
52. Gautam M, Cheruvattath R, Balan V: Recurrence of autoimmune liver disease after liver transplantation: a systematic review. Liver Transpl 2006; 12: 1813-1824. (Pubitemid 44911808)
53. Rowe IA, Webb K, Gunson BK, Mehta N, Haque S, Neuberger J: The impact of disease recurrence on graft survival following liver transplantation: a single centre experience. Transpl Int 2008; 21: 459-465. (Pubitemid 351490169)
54. Campsen J, Zimmerman MA, Trotter JF, Wachs M, Bak T, Steinberg T, Kaplan M, Wright F, Kam I: Liver transplantation for autoimmune hepatitis and the success of aggressive corticosteroid withdrawal. Liver Transpl 2008; 14: 1281-1286.
55. Kerkar N, Hadzic N, Davies ET, Portmann B, Donaldson PT, Rela M, Heaton ND, Vergani D, Mieli-Vergani G: De-novo autoimmune hepatitis after liver transplantation. Lancet 1998; 351: 409-413. (Pubitemid 28064165)
56. Salcedo M, Vaquero J, Banares R, Rodriguez-Mahou M, Alvarez E, Vicario JL, Hernandez-Albujar A, Tiscar JL, Rincon D, Alonso S, et al: Response to steroids in de novo autoimmune hepatitis after liver transplantation. Hepatology 2002; 35: 349-356. (Pubitemid 34106374)
57. Jones DE, James OF, Portmann B, Burt AD, Williams R, Hudson M: Development of autoimmune hepatitis following liver transplantation for primary biliary cirrhosis. Hepatology 1999; 30: 53-57. (Pubitemid 29300568)