Cytochrome P450 2A isoenzymes in freshly prepared blood lymphocytes isolated from rats and validation as a biomarker for clinical studies in humans

Xenobiotica

Volumn 43, Issue 4, 2013, Pages 311-319

  Sharma, Amit ^a,b   Dinesh, Konka ^a   Yadav, Sanjay ^a   Jain, Swatantra K ^b   Pant, Mohan C ^c   Parmar, Devendra ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

^b HAMDARD UNIVERSITY   (India)

^c KING GEORGE'S MEDICAL UNIVERSITY   (India)

Author keywords

Biomarker; CYP2A; Lung cancer; MRNA; Protein

Indexed keywords

BIOLOGICAL MARKER; CELL AND TISSUE ENZYMES; COUMARIN HYDROXYLASE; CYTOCHROME P450 2A; MESSENGER RNA; OXYGENASE; POLYCYCLIC AROMATIC HYDROCARBON; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BLOOD ANALYSIS; CANCER PATIENT; CELL ISOLATION; CLINICAL ARTICLE; CONTROLLED STUDY; ENVIRONMENT; FEMALE; GENE EXPRESSION PROFILING; GENOTYPE; HUMAN; LUNG CANCER; MALE; NONHUMAN; PERIPHERAL LYMPHOCYTE; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SCREENING TEST; VALIDATION PROCESS; WESTERN BLOTTING;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CELL SEPARATION; ENZYME INHIBITORS; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; ISOENZYMES; KINETICS; LYMPHOCYTES; MALE; RATS; RATS, WISTAR; REAL-TIME POLYMERASE CHAIN REACTION; REPRODUCIBILITY OF RESULTS;

RATTUS;

EID: 84879548835     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.3109/00498254.2012.717728     Document Type: Article

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