The Overexpression of Twinkle Helicase Ameliorates the Progression of Cardiac Fibrosis and Heart Failure in Pressure Overload Model in Mice

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Tanaka, Atsushi ^a   Ide, Tomomi ^a   Fujino, Takeo ^a   Onitsuka, Ken ^a   Ikeda, Masataka ^a   Takehara, Takako ^a   Hata, Yuko ^a   Ylikallio, Emil ^b   Tyynismaa, Henna ^b   Suomalainen, Anu ^b   Sunagawa, Kenji ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ANGIOTENSIN II; COLLAGEN TYPE 1; COLLAGEN TYPE 3; CONNECTIVE TISSUE GROWTH FACTOR; HELICASE; MESSENGER RNA; MITOCHONDRIAL DNA; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA CONSTRICTION; ARTICLE; CONTROLLED STUDY; COPY NUMBER VARIATION; DISEASE COURSE; ECHOCARDIOGRAPHY; FIBROBLAST; FIBROSING ALVEOLITIS; HEART FAILURE; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE OVERLOAD; HEART MUSCLE FIBROSIS; HEART VENTRICLE HYPERTROPHY; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; POSTERIOR MYOCARDIAL INFARCTION; PROTEIN EXPRESSION; WILD TYPE;

ANIMALS; AORTA; CONSTRICTION; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DNA COPY NUMBER VARIATIONS; DNA HELICASES; ECHOCARDIOGRAPHY; FIBROSIS; GENE EXPRESSION; HEART; HEART FAILURE; HYPERTROPHY, LEFT VENTRICULAR; MALE; MICE; MICE, TRANSGENIC; MITOCHONDRIAL PROTEINS; PRESSURE; VENTRICULAR FUNCTION, LEFT; VENTRICULAR REMODELING;

ADENOVIRIDAE; MUS; MUS MUSCULUS;

EID: 84879533889     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0067642     Document Type: Article

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