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Volumn 8, Issue 6, 2013, Pages

Lack of Plasma Protein Hemopexin Results in Increased Duodenal Iron Uptake

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE PHASE PROTEIN; FERRITIN; FERROUS SULFATE; HEME; HEME OXYGENASE; HEMOPEXIN; IRON; IRON 57; APOFERRITIN;

EID: 84879531505     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0068146     Document Type: Article
Times cited : (13)

References (32)
  • 1
    • 33846691564 scopus 로고    scopus 로고
    • Iron uptake and metabolism in the new millennium
    • doi: 10.1016/j.tcb.2006.12.003
    • Dunn LL, Rahmanto YS, Richardson DR, (2007) Iron uptake and metabolism in the new millennium. Trends Cell Biol 17: 93-100. doi:10.1016/j.tcb.2006.12.003. PubMed: 17194590.
    • (2007) Trends Cell Biol , vol.17 , pp. 93-100
    • Dunn, L.L.1    Rahmanto, Y.S.2    Richardson, D.R.3
  • 2
    • 33144479357 scopus 로고    scopus 로고
    • Role of ABCG2/BCRP in biology and medicine
    • doi: 10.1146/annurev.pharmtox.46.120604.141238
    • Krishnamurthy P, Schuetz JD, (2006) Role of ABCG2/BCRP in biology and medicine. Annu Rev Pharmacol Toxicol 46: 381-410. doi:10.1146/annurev.pharmtox.46.120604.141238. PubMed: 16402910.
    • (2006) Annu Rev Pharmacol Toxicol , vol.46 , pp. 381-410
    • Krishnamurthy, P.1    Schuetz, J.D.2
  • 3
    • 38949097546 scopus 로고    scopus 로고
    • A heme export protein is required for red blood cell differentiation and iron homeostasis
    • doi: 10.1126/science.1151133
    • Keel SB, Doty RT, Yang Z, Quigley JG, Chen J, et al. (2008) A heme export protein is required for red blood cell differentiation and iron homeostasis. Science 319: 825-828. doi:10.1126/science.1151133. PubMed: 18258918.
    • (2008) Science , vol.319 , pp. 825-828
    • Keel, S.B.1    Doty, R.T.2    Yang, Z.3    Quigley, J.G.4    Chen, J.5
  • 4
    • 84870514416 scopus 로고    scopus 로고
    • The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation
    • doi: 10.1172/JCI62422
    • Chiabrando D, Marro S, Mercurio S, Giorgi C, Petrillo S, et al. (2012) The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation. J Clin Invest 122: 4569-4579. doi:10.1172/JCI62422. PubMed: 23187127.
    • (2012) J Clin Invest , vol.122 , pp. 4569-4579
    • Chiabrando, D.1    Marro, S.2    Mercurio, S.3    Giorgi, C.4    Petrillo, S.5
  • 5
    • 77955610477 scopus 로고    scopus 로고
    • Iron-sensing proteins that regulate hepcidin and enteric iron absorption
    • doi: 10.1146/annurev.nutr.012809.104801
    • Knutson MD, (2010) Iron-sensing proteins that regulate hepcidin and enteric iron absorption. Annu Rev Nutr 30: 149-171. doi:10.1146/annurev.nutr.012809.104801. PubMed: 20415583.
    • (2010) Annu Rev Nutr , vol.30 , pp. 149-171
    • Knutson, M.D.1
  • 6
    • 79952162002 scopus 로고    scopus 로고
    • Regulation of cellular iron metabolism
    • doi: 10.1042/BJ20101825
    • Wang J, Pantopoulos K, (2011) Regulation of cellular iron metabolism. Biochem J 434: 365-381. doi:10.1042/BJ20101825. PubMed: 21348856.
    • (2011) Biochem J , vol.434 , pp. 365-381
    • Wang, J.1    Pantopoulos, K.2
  • 7
    • 84861355868 scopus 로고    scopus 로고
    • Hepcidin and iron homeostasis
    • doi: 10.1016/j.bbamcr.2012.01.014
    • Ganz T, Nemeth E, (2012) Hepcidin and iron homeostasis. Biochim Biophys Acta 1823: 1434-1443. doi:10.1016/j.bbamcr.2012.01.014. PubMed: 22306005.
    • (2012) Biochim Biophys Acta , vol.1823 , pp. 1434-1443
    • Ganz, T.1    Nemeth, E.2
  • 8
    • 77953854244 scopus 로고    scopus 로고
    • Hypoxic regulation of erythropoiesis and iron metabolism
    • doi: 10.1152/ajpcell.00084.2010
    • Haase VH, (2010) Hypoxic regulation of erythropoiesis and iron metabolism. Am J Physiol Renal Physiol 299: F1-13. doi:10.1152/ajpcell.00084.2010. PubMed: 20444740.
    • (2010) Am J Physiol Renal Physiol , vol.299 , pp. 1-13
    • Haase, V.H.1
  • 9
    • 38349111676 scopus 로고    scopus 로고
    • Role of the hypoxia inducible factors HIF in iron metabolism
    • doi: 10.4161/cc.7.1.5145
    • Peyssonnaux C, Nizet V, Johnson RS, (2008) Role of the hypoxia inducible factors HIF in iron metabolism. Cell Cycle 7: 28-32. doi:10.4161/cc.7.1.5145. PubMed: 18212530.
    • (2008) Cell Cycle , vol.7 , pp. 28-32
    • Peyssonnaux, C.1    Nizet, V.2    Johnson, R.S.3
  • 10
    • 84869886792 scopus 로고    scopus 로고
    • Cell-specific regulation of Ferroportin transcription following experimentally-induced acute anemia in mice
    • doi: 10.1016/j.bcmd.2012.08.002
    • Chiabrando D, Fiorito V, Marro S, Silengo L, Altruda F, et al. (2013) Cell-specific regulation of Ferroportin transcription following experimentally-induced acute anemia in mice. Blood Cells Mol Dis 50: 25-30. doi:10.1016/j.bcmd.2012.08.002. PubMed: 22921471.
    • (2013) Blood Cells Mol Dis , vol.50 , pp. 25-30
    • Chiabrando, D.1    Fiorito, V.2    Marro, S.3    Silengo, L.4    Altruda, F.5
  • 11
    • 79951679054 scopus 로고    scopus 로고
    • Regulation of iron pathways in response to hypoxia
    • doi: 10.1016/j.freeradbiomed.2010.12.023
    • Chepelev NL, Willmore WG, (2011) Regulation of iron pathways in response to hypoxia. Free Radic Biol Med 50: 645-666. doi:10.1016/j.freeradbiomed.2010.12.023. PubMed: 21185934.
    • (2011) Free Radic Biol Med , vol.50 , pp. 645-666
    • Chepelev, N.L.1    Willmore, W.G.2
  • 12
    • 77949497609 scopus 로고    scopus 로고
    • Heme scavenging and the other facets of hemopexin
    • doi: 10.1089/ars.2009.2787
    • Tolosano E, Fagoonee S, Morello N, Vinchi F, Fiorito V, (2010) Heme scavenging and the other facets of hemopexin. Antioxid Redox Signal 12: 305-320. doi:10.1089/ars.2009.2787. PubMed: 19650691.
    • (2010) Antioxid Redox Signal , vol.12 , pp. 305-320
    • Tolosano, E.1    Fagoonee, S.2    Morello, N.3    Vinchi, F.4    Fiorito, V.5
  • 14
    • 46749135674 scopus 로고    scopus 로고
    • Hemopexin prevents endothelial damage and liver congestion in a mouse model of heme overload
    • doi: 10.2353/ajpath.2008.071130
    • Vinchi F, Gastaldi S, Silengo L, Altruda F, Tolosano E, (2008) Hemopexin prevents endothelial damage and liver congestion in a mouse model of heme overload. Am J Pathol 173: 289-299. doi:10.2353/ajpath.2008.071130. PubMed: 18556779.
    • (2008) Am J Pathol , vol.173 , pp. 289-299
    • Vinchi, F.1    Gastaldi, S.2    Silengo, L.3    Altruda, F.4    Tolosano, E.5
  • 15
    • 77953713414 scopus 로고    scopus 로고
    • Heme controls ferroportin1 (FPN1) transcription involving Bach1, Nrf2 and a MARE/ARE sequence motif at position -7007 of the FPN1 promoter
    • doi: 10.3324/haematol.2009.020123
    • Marro S, Chiabrando D, Messana E, Stolte J, Turco E, et al. (2010) Heme controls ferroportin1 (FPN1) transcription involving Bach1, Nrf2 and a MARE/ARE sequence motif at position-7007 of the FPN1 promoter. Haematologica 95: 1261-1268. doi:10.3324/haematol.2009.020123. PubMed: 20179090.
    • (2010) Haematologica , vol.95 , pp. 1261-1268
    • Marro, S.1    Chiabrando, D.2    Messana, E.3    Stolte, J.4    Turco, E.5
  • 16
    • 34848925133 scopus 로고    scopus 로고
    • Lack of haptoglobin affects iron transport across duodenum by modulating ferroportin expression
    • doi: 10.1053/j.gastro.2007.07.004
    • Marro S, Barisani D, Chiabrando D, Fagoonee S, Muckenthaler MU, et al. (2007) Lack of haptoglobin affects iron transport across duodenum by modulating ferroportin expression. Gastroenterology 133: 1261-1271. doi:10.1053/j.gastro.2007.07.004. PubMed: 17919498.
    • (2007) Gastroenterology , vol.133 , pp. 1261-1271
    • Marro, S.1    Barisani, D.2    Chiabrando, D.3    Fagoonee, S.4    Muckenthaler, M.U.5
  • 17
    • 77449150120 scopus 로고    scopus 로고
    • Haemopexin affects iron distribution and ferritin expression in mouse brain
    • doi: 10.1111/j.1582-4934.2008.00611.x
    • Morello N, Tonoli E, Logrand F, Fiorito V, Fagoonee S, et al. (2009) Haemopexin affects iron distribution and ferritin expression in mouse brain. J Cell Mol Med 13: 4192-4204. doi:10.1111/j.1582-4934.2008.00611.x. PubMed: 19120692.
    • (2009) J Cell Mol Med , vol.13 , pp. 4192-4204
    • Morello, N.1    Tonoli, E.2    Logrand, F.3    Fiorito, V.4    Fagoonee, S.5
  • 18
    • 84870253390 scopus 로고    scopus 로고
    • Assessment of iron absorption in mice by ICP-MS measurements of (57)Fe levels
    • doi: 10.1007/s00394-011-0256-6
    • Fiorito V, Geninatti Crich S, Silengo L, Altruda F, Aime S, et al. (2012) Assessment of iron absorption in mice by ICP-MS measurements of (57)Fe levels. Eur J Nutr 51: 783-789. doi:10.1007/s00394-011-0256-6. PubMed: 22009264.
    • (2012) Eur J Nutr , vol.51 , pp. 783-789
    • Fiorito, V.1    Geninatti Crich, S.2    Silengo, L.3    Altruda, F.4    Aime, S.5
  • 19
    • 0034130261 scopus 로고    scopus 로고
    • Functional and immunological analysis of recombinant mouse H- and L-ferritins from Escherichia coli
    • doi: 10.1006/prep.2000.1212
    • Santambrogio P, Cozzi A, Levi S, Rovida E, Magni F, et al. (2000) Functional and immunological analysis of recombinant mouse H- and L-ferritins from Escherichia coli. Protein Expr Purif 19: 212-218. doi:10.1006/prep.2000.1212. PubMed: 10833409.
    • (2000) Protein Expr Purif , vol.19 , pp. 212-218
    • Santambrogio, P.1    Cozzi, A.2    Levi, S.3    Rovida, E.4    Magni, F.5
  • 20
    • 0034733635 scopus 로고    scopus 로고
    • A novel mammalian iron-regulated protein involved in intracellular iron metabolism
    • doi: 10.1074/jbc.M000713200
    • Abboud S, Haile DJ, (2000) A novel mammalian iron-regulated protein involved in intracellular iron metabolism. J Biol Chem 275: 19906-19912. doi:10.1074/jbc.M000713200. PubMed: 10747949.
    • (2000) J Biol Chem , vol.275 , pp. 19906-19912
    • Abboud, S.1    Haile, D.J.2
  • 21
    • 0035865527 scopus 로고    scopus 로고
    • Expression of the DMT1 (NRAMP2/DCT1) iron transporter in mice with genetic iron overload disorders
    • doi: 10.1182/blood.V97.4.1138
    • Canonne-Hergaux F, Levy JE, Fleming MD, Montross LK, Andrews NC, et al. (2001) Expression of the DMT1 (NRAMP2/DCT1) iron transporter in mice with genetic iron overload disorders. Blood 97: 1138-1140. doi:10.1182/blood.V97.4.1138. PubMed: 11159549.
    • (2001) Blood , vol.97 , pp. 1138-1140
    • Canonne-Hergaux, F.1    Levy, J.E.2    Fleming, M.D.3    Montross, L.K.4    Andrews, N.C.5
  • 22
    • 24144459870 scopus 로고    scopus 로고
    • Identification of an intestinal heme transporter
    • doi: 10.1016/j.cell.2005.06.025
    • Shayeghi M, Latunde-Dada GO, Oakhill JS, Laftah AH, Takeuchi K, et al. (2005) Identification of an intestinal heme transporter. Cell 122: 789-801. doi:10.1016/j.cell.2005.06.025. PubMed: 16143108.
    • (2005) Cell , vol.122 , pp. 789-801
    • Shayeghi, M.1    Latunde-Dada, G.O.2    Oakhill, J.S.3    Laftah, A.H.4    Takeuchi, K.5
  • 23
    • 0036566143 scopus 로고    scopus 로고
    • Expression of the two mRNA isoforms of the iron transporter Nramp2/DMTI in mice and function of the iron responsive element
    • doi: 10.1042/0264-6021:3630449
    • Tchernitchko D, Bourgeois M, Martin ME, Beaumont C, (2002) Expression of the two mRNA isoforms of the iron transporter Nramp2/DMTI in mice and function of the iron responsive element. Biochem J 363: 449-455. doi:10.1042/0264-6021:3630449. PubMed: 11964145.
    • (2002) Biochem J , vol.363 , pp. 449-455
    • Tchernitchko, D.1    Bourgeois, M.2    Martin, M.E.3    Beaumont, C.4
  • 24
    • 65349126484 scopus 로고    scopus 로고
    • A ferroportin transcript that lacks an iron-responsive element enables duodenal and erythroid precursor cells to evade translational repression
    • doi: 10.1016/j.cmet.2009.03.006
    • Zhang DL, Hughes RM, Ollivierre-Wilson H, Ghosh MC, Rouault TA, (2009) A ferroportin transcript that lacks an iron-responsive element enables duodenal and erythroid precursor cells to evade translational repression. Cell Metab 9: 461-473. doi:10.1016/j.cmet.2009.03.006. PubMed: 19416716.
    • (2009) Cell Metab , vol.9 , pp. 461-473
    • Zhang, D.L.1    Hughes, R.M.2    Ollivierre-Wilson, H.3    Ghosh, M.C.4    Rouault, T.A.5
  • 25
    • 0033485566 scopus 로고    scopus 로고
    • Defective recovery and severe renal damage after acute hemolysis in hemopexin-deficient mice
    • doi: 10572107
    • Tolosano E, Hirsch E, Patrucco E, Camaschella C, Navone R, et al. (1999) Defective recovery and severe renal damage after acute hemolysis in hemopexin-deficient mice. Blood 94: 3906-3914. PubMed: 10572107.
    • (1999) Blood , vol.94 , pp. 3906-3914
    • Tolosano, E.1    Hirsch, E.2    Patrucco, E.3    Camaschella, C.4    Navone, R.5
  • 26
    • 0037093202 scopus 로고    scopus 로고
    • Regulation of ferritin genes and protein
    • doi: 10.1182/blood.V99.10.3505
    • Torti FM, Torti SV, (2002) Regulation of ferritin genes and protein. Blood 99: 3505-3516. doi:10.1182/blood.V99.10.3505. PubMed: 11986201.
    • (2002) Blood , vol.99 , pp. 3505-3516
    • Torti, F.M.1    Torti, S.V.2
  • 27
    • 0037372606 scopus 로고    scopus 로고
    • A rapid decrease in the expression of DMT1 and Dcytb but not Ireg1 or hephaestin explains the mucosal block phenomenon of iron absorption
    • doi: 10.1136/gut.52.3.340
    • Frazer DM, Wilkins SJ, Becker EM, Murphy TL, Vulpe CD, et al. (2003) A rapid decrease in the expression of DMT1 and Dcytb but not Ireg1 or hephaestin explains the mucosal block phenomenon of iron absorption. Gut 52: 340-346. doi:10.1136/gut.52.3.340. PubMed: 12584213.
    • (2003) Gut , vol.52 , pp. 340-346
    • Frazer, D.M.1    Wilkins, S.J.2    Becker, E.M.3    Murphy, T.L.4    Vulpe, C.D.5
  • 28
    • 77956547392 scopus 로고    scopus 로고
    • Kinetics and specificity of feline leukemia virus subgroup C receptor (FLVCR) export function and its dependence on hemopexin
    • doi: 10.1074/jbc.M110.119131
    • Yang Z, Philips JD, Doty RT, Giraudi P, Ostrow JD, et al. (2010) Kinetics and specificity of feline leukemia virus subgroup C receptor (FLVCR) export function and its dependence on hemopexin. J Biol Chem 285: 28874-28882. doi:10.1074/jbc.M110.119131. PubMed: 20610401.
    • (2010) J Biol Chem , vol.285 , pp. 28874-28882
    • Yang, Z.1    Philips, J.D.2    Doty, R.T.3    Giraudi, P.4    Ostrow, J.D.5
  • 29
    • 0015698073 scopus 로고
    • Plasma clearance of 125I-labelled haemopexin in normal and haem-loaded rabbits
    • doi: 10.1111/j.1365-2141.1973.tb01764.x
    • Lane RS, Rangeley DM, Liem HH, Wormsley S, Muller-Eberhard U, (1973) Plasma clearance of 125I-labelled haemopexin in normal and haem-loaded rabbits. Br J Haematol 25: 533-540. doi:10.1111/j.1365-2141.1973.tb01764.x. PubMed: 4127614.
    • (1973) Br J Haematol , vol.25 , pp. 533-540
    • Lane, R.S.1    Rangeley, D.M.2    Liem, H.H.3    Wormsley, S.4    Muller-Eberhard, U.5
  • 30
    • 0041672570 scopus 로고    scopus 로고
    • Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation
    • doi: 10.1182/blood-2003-03-0672
    • Ganz T, (2003) Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation. Blood 102: 783-788. doi:10.1182/blood-2003-03-0672. PubMed: 12663437.
    • (2003) Blood , vol.102 , pp. 783-788
    • Ganz, T.1
  • 31
    • 27144551314 scopus 로고    scopus 로고
    • Identification of the receptor scavenging hemopexin-heme complexes
    • doi: 10.1182/blood-2005-03-1185
    • Hvidberg V, Maniecki MB, Jacobsen C, Højrup P, Møller HJ, et al. (2005) Identification of the receptor scavenging hemopexin-heme complexes. Blood 106: 2572-2579. doi:10.1182/blood-2005-03-1185. PubMed: 15947085.
    • (2005) Blood , vol.106 , pp. 2572-2579
    • Hvidberg, V.1    Maniecki, M.B.2    Jacobsen, C.3    Højrup, P.4    Møller, H.J.5
  • 32
    • 34548159927 scopus 로고    scopus 로고
    • Interaction of heme and heme-hemopexin with an extracellular oxidant system used to measure cell growth-associated plasma membrane electron transport
    • doi: 10.1016/j.bbabio.2007.06.003
    • Rish KR, Swartzlander R, Sadikot TN, Berridge MV, Smith A, (2007) Interaction of heme and heme-hemopexin with an extracellular oxidant system used to measure cell growth-associated plasma membrane electron transport. Biochim Biophys Acta 1767: 1107-1117. doi:10.1016/j.bbabio.2007.06.003. PubMed: 17643387.
    • (2007) Biochim Biophys Acta , vol.1767 , pp. 1107-1117
    • Rish, K.R.1    Swartzlander, R.2    Sadikot, T.N.3    Berridge, M.V.4    Smith, A.5


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