Structural Insights into the Effector - Immunity System Tae4/Tai4 from Salmonella typhimurium

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Benz, Juliane ^a   Reinstein, Jochen ^a   Meinhart, Anton ^a  

^a MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDASE; BACTERIAL PROTEIN; DIAMINOPIMELIC ACID; EFFECTOR PROTEIN; HYDROLASE; IMMUNITY PROTEIN; MULTIPROTEIN COMPLEX; PEPTIDOGLYCAN; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG; BACTERIAL SECRETION SYSTEM; N ACETYLMURAMOYLALANINE AMIDASE;

ARTICLE; BACTERIAL IMMUNITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOLYSIS; CYTOPLASM; ENZYME INHIBITION; ENZYME SPECIFICITY; GRAM NEGATIVE BACTERIUM; NONHUMAN; NUCLEOTIDE SEQUENCE; OPERON; PROTEIN DEGRADATION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN STRUCTURE; SALMONELLA TYPHIMURIUM; TYPE VI SECRETION SYSTEM; AMINO ACID SEQUENCE; BACTERIAL SECRETION SYSTEM; CHEMISTRY; ENZYME ACTIVE SITE; GROWTH, DEVELOPMENT AND AGING; IMMUNE SYSTEM; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; PROTEIN MULTIMERIZATION; PROTEIN TERTIARY STRUCTURE; SALMONELLA ENTERICA SEROVAR TYPHIMURIUM; SEQUENCE HOMOLOGY; X RAY CRYSTALLOGRAPHY;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; SALMONELLA TYPHIMURIUM;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BACTERIAL SECRETION SYSTEMS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; IMMUNE SYSTEM; N-ACETYLMURAMOYL-L-ALANINE AMIDASE; PEPTIDOGLYCAN; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; SALMONELLA TYPHIMURIUM; SEQUENCE HOMOLOGY; SUBSTRATE SPECIFICITY;

EID: 84879522315     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0067362     Document Type: Article

References (40)

1. Riley MA, Wertz JE, (2002) Bacteriocins: evolution, ecology, and application. Annu Rev Microbiol 56: 117-137.
2. Gerlach RG, Hensel M, (2007) Protein secretion systems and adhesins: the molecular armory of Gram-negative pathogens. Int J Med Microbiol 297(6): 401-415.
3. Russell AB, Hood RD, Bui NK, LeRoux M, Vollmer W, et al. (2011) Type VI secretion delivers bacteriolytic effectors to target cells. Nature 475(7356): 343-347.
4. Russell AB, Singh P, Brittnacher M, Bui NK, Hood RD, et al. (2012) A Widespread Bacterial Type VI Secretion Effector Superfamily Identified Using a Heuristic Approach. Cell Host Microbe 11(5): 538-549.
5. Basler M, Pilhofer M, Henderson GP, Jensen GJ, Mekalanos JJ, (2012) Type VI secretion requires a dynamic contractile phage tail-like structure. Nature 483(7388): 182-186.
6. Boyer F, Fichant G, Berthod J, Vandenbrouck Y, Attree I, (2009) Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources? BMC Genomics 10: 104.
7. Cascales E, (2008) The type VI secretion toolkit. EMBO Rep 9(8): 735-741.
8. Leiman PG, Basler M, Ramagopal UA, Bonanno JB, Sauder JM, et al. (2009) Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin. Proc Natl Acad Sci U S A 106(11): 4154-4159.
9. Pell LG, Kanelis V, Donaldson LW, Howell PL, Davidson AR, (2009) The phage lambda major tail protein structure reveals a common evolution for long-tailed phages and the type VI bacterial secretion system. Proc Natl Acad Sci U S A 106(11): 4160-4165.
10. Mougous JD, Cuff ME, Raunser S, Shen A, Zhou M, et al. (2006) A virulence locus of Pseudomonas aeruginosa encodes a protein secretion apparatus. Science 312(5779): 1526-1530.
11. English G, Trunk K, Rao VA, Srikannathasan V, Hunter WN et al. (2012) New secreted toxins and immunity proteins encoded within the Type VI secretion system gene cluster of Serratia marcescens. Mol Microbiol.
12. Bingle LE, Bailey CM, Pallen MJ, (2008) Type VI secretion: a beginner's guide. Curr Opin Microbiol 11(1): 3-8.
13. Hood RD, Singh P, Hsu F, Guvener T, Carl MA, et al. (2010) A type VI secretion system of Pseudomonas aeruginosa targets a toxin to bacteria. Cell Host Microbe 7(1): 25-37.
14. Ding J, Wang W, Feng H, Zhang Y, Wang DC, (2012) Structural insights into the Pseudomonas aeruginosa type VI virulence effector Tse1 bacteriolysis and self-protection mechanisms. J Biol Chem 287(32): 26911-26920.
15. Benz J, Sendlmeier C, Barends TR, Meinhart A, (2012) Structural insights into the effector-immunity system Tse1/Tsi1 from Pseudomonas aeruginosa. PLoS One 7(7): e40453.
16. Shang G, Liu X, Lu D, Zhang J, Li N, et al. (2012) Structural insight into how Pseudomonas aeruginosa peptidoglycanhydrolase Tse1 and its immunity protein Tsi1 function. Biochem J 448(2): 201-211.
17. Zhang H, Zhang H, Gao ZQ, Wang WJ, Liu GF, et al. (2013) Structure of the type VI effector-immunity complex (Tae4-Tai4) provides novel insights into the inhibition mechanism of the effector by its immunity protein. J Biol Chem 288(8): 5928-5939.
18. Anantharaman V, Aravind L, (2003) Evolutionary history, structural features and biochemical diversity of the NlpC/P60 superfamily of enzymes. Genome Biol 4(2): R11.
19. Holm L, Rosenstrom P (2010) Dali server: conservation mapping in 3D. Nucleic Acids Res 38(Web Server issue): W545-549.
20. Chou S, Bui NK, Russell AB, Lexa KW, Gardiner TE, et al. (2012) Structure of a peptidoglycan amidase effector targeted to Gram-negative bacteria by the type VI secretion system. Cell Rep 1(6): 656-664.
21. Zhang H, Gao ZQ, Su XD, Dong YH, (2012) Crystal structure of type VI effector Tse1 from Pseudomonas aeruginosa. FEBS Lett 586(19): 3193-3199.
22. Xu Q, Abdubek P, Astakhova T, Axelrod HL, Bakolitsa C, et al. (2010) Structure of the gamma-D-glutamyl-L-diamino acid endopeptidase YkfC from Bacillus cereus in complex with L-Ala-gamma-D-Glu: insights into substrate recognition by NlpC/P60 cysteine peptidases. Acta Crystallogr Sect F Struct Biol Cryst Commun 66(Pt 10): 1354-1364.
23. Storer AC, Menard R, (1994) Catalytic mechanism in papain family of cysteine peptidases. Methods Enzymol 244: 486-500.
24. Robertus JD, Kraut J, Alden RA, Birktoft JJ, (1972) Subtilisin; a stereochemical mechanism involving transition-state stabilization. Biochemistry 11(23): 4293-4303.
25. Hedstrom L, (2002) Serine protease mechanism and specificity. Chem Rev 102(12): 4501-4524.
26. Ekici OD, Paetzel M, Dalbey RE, (2008) Unconventional serine proteases: variations on the catalytic Ser/His/Asp triad configuration. Protein Sci 17(12): 2023-2037.
27. Polgár L, (2005) The catalytic triad of serine peptidases. Cell Mol Life Sci 62(19-20): 2161-2172.
28. Palzkill T, Le QQ, Wong A, Botstein D, (1994) Selection of functional signal peptide cleavage sites from a library of random sequences. J Bacteriol 176(3): 563-568.
29. Van Duyne GD, Standaert RF, Karplus PA, Schreiber SL, Clardy J, (1993) Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin. J Mol Biol 229(1): 105-124.
30. Kabsch W, (1993) Automatic Processing of Rotation Diffraction Data from Crystals of Initially Unknown Symmetry and Cell Constants. J Appl Crystallogr 26: 795-800.
31. Sheldrick GM, (2008) A short history of SHELX. Acta Crystallogr A 64(Pt 1): 112-122.
32. Emsley P, Cowtan K, (2004) Coot: model-building tools for molecular graphics. Acta Crystallogr D Biol Crystallogr 60(Pt 12 Pt 1): 2126-2132.
33. Murshudov GN, Vagin AA, Dodson EJ, (1997) Refinement of macromolecular structures by the maximum-likelihood method. Acta Crystallogr D Biol Crystallogr 53(Pt 3): 240-255.
34. Winn MD, Isupov MN, Murshudov GN, (2001) Use of TLS parameters to model anisotropic displacements in macromolecular refinement. Acta Crystallogr D Biol Crystallogr 57(Pt 1): 122-133.
35. Winn MD, Ballard CC, Cowtan KD, Dodson EJ, Emsley P, et al. (2011) Overview of the CCP4 suite and current developments. Acta Crystallogr D Biol Crystallogr 67(Pt 4): 235-242.
36. Davis IW, Leaver-Fay A, Chen VB, Block JN, Kapral GJ et al. (2007) MolProbity: all-atom contacts and structure validation for proteins and nucleic acids. Nucleic Acids Res 35(Web Server issue): W375-383.
37. DeLano WL (2002) The PyMOL Molecular Graphics System. DeLano Scientific LLC, San Carlos, California, USA.
38. Livingstone CD, Barton GJ, (1993) Protein sequence alignments: a strategy for the hierarchical analysis of residue conservation. Comput Appl Biosci 9(6): 745-756.
39. Barton GJ, (1993) ALSCRIPT: a tool to format multiple sequence alignments. Protein Eng 6(1): 37-40.
40. Krissinel E, Henrick K, (2007) Inference of macromolecular assemblies from crystalline state. J Mol Biol 372(3): 774-797.