Spray-dried voriconazole-cyclodextrin complexes: Solubility, dissolution rate and chemical stability

Carbohydrate Polymers

Volumn 98, Issue 1, 2013, Pages 122-131

  Miletic, Tijana ^a   Kyriakos, Kachrimanis ^c   Graovac, Adrijana ^a   Ibric, Svetlana ^b  

^a Research and Development   (Serbia)

^b Faculty of Pharmacy   (Serbia)

^c ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

Cyclodextrins; Dissolution; Molecular docking; Solubility; Stability; Voriconazole

Indexed keywords

BINDING ENERGY; BINDING SITES; CHEMICAL BONDS; CHEMICAL STABILITY; COMPLEX NETWORKS; CONVERGENCE OF NUMERICAL METHODS; DISSOLUTION; FOURIER TRANSFORM INFRARED SPECTROSCOPY; IMPURITIES; MIXTURES; MOLECULAR MODELING; SOLUBILITY; SOLUTIONS; SPRAY DRYING;

BINDING AFFINITIES; CYCLODEXTRIN COMPLEXES; DEGRADATION IMPURITIES; H-BONDING NETWORKS; MOLECULAR DOCKING; MOLECULAR DOCKING SIMULATIONS; SOLUBILITY STUDIES; VORICONAZOLE;

CYCLODEXTRINS;

2 HYDROXYPROPYL BETA CYCLODEXTRIN; 2-HYDROXYPROPYL-BETA-CYCLODEXTRIN; BETA CYCLODEXTRIN DERIVATIVE; CYCLODEXTRIN; METHYL BETA CYCLODEXTRIN; METHYL-BETA-CYCLODEXTRIN; PYRIMIDINE DERIVATIVE; TRIAZOLE DERIVATIVE; VORICONAZOLE;

ARTICLE; CHEMISTRY; CONFORMATION; DISSOLUTION; DRUG STABILITY; MOLECULAR DOCKING; SOLUBILITY; STABILITY; TEMPERATURE;

CYCLODEXTRINS; DISSOLUTION; MOLECULAR DOCKING; SOLUBILITY; STABILITY; VORICONAZOLE;

BETA-CYCLODEXTRINS; CARBOHYDRATE CONFORMATION; DRUG STABILITY; MOLECULAR DOCKING SIMULATION; PYRIMIDINES; SOLUBILITY; TEMPERATURE; TRIAZOLES;

EID: 84879493192     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2013.05.084     Document Type: Article

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