TIFA upregulation after hypoxia-reoxygenation is TLR4- and MyD88-dependent and associated with HMGB1 upregulation and release

Free Radical Biology and Medicine

Volumn 63, Issue , 2013, Pages 361-367

  Ding, Ning ^a,b   Zhang, Yong ^a   Loughran, Patricia A ^a   Wang, Qingde ^a   Tsung, Allan ^a   Billiar, Timothy R ^a  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b GUANGZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Free radicals; Hypoxia; Inflammation; Liver; TIFA; TLR4

Indexed keywords

BINDING PROTEIN; HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 4; TRAF INTERACTING PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE SILENCING; HEMORRHAGIC SHOCK; HYPOXIA; IN VITRO STUDY; LIVER CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; REOXYGENATION; RESUSCITATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

MUS;

EID: 84879486251     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.05.029     Document Type: Article

References (28)

1. Baue, A. E.; Durham, R.; Faist, E. Systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), multiple organ failure (MOF): are we winning the battle? Shock 10: 79-89; 1998. (Pubitemid 128463838)
2. Dewar, D.; Moore, F. A.; Moore, E. E.; Balogh, Z. Postinjury multiple organ failure. Injury 40: 912-918; 2009.
3. Shenkar, R.; Coulson, W. F.; Abraham, E. Hemorrhage and resuscitation induce alterations in cytokine expression and the development of acute lung injury. Am. J. Respir. Cell Mol. Biol. 10: 290-297; 1994.
4. Lichtman, S. N.; Lemasters, J. J. Role of cytokines and cytokine-producing cells in reperfusion injury to the liver. Semin. Liver Dis 19: 17 1 -187; 1999.
5. Jarrar, D.; Chaudry, I. H.; Wang, P. Organ dysfunction following hemorrhage and sepsis: mechanisms and therapeutic approaches. Int. J. Mol. Med. 4: 575-583; 1999.
6. Namas, R.; Ghuma, A.; Torres, A.; Polanco, P.; Gomez, H.; Barclay, D., et al. An adequately robust early TNF-alpha response is a hallmark of survival following trauma/hemorrhage. PLoS One 4:e8406; 2009.
7. Nathan, C. Points of control in inflammation. Nature 420: 846-852; 2002. (Pubitemid 36019637)
8. Yang, R.; Harada, T.; Mollen, K. P.; Prince, J. M.; Levy, R. M.; Englert, J. A., et al. Anti-HMGB1 neutralizing antibody ameliorates gut barrier dysfunction and improves survival after hemorrhagic shock. Mol. Med. 12: 105-114; 2006. (Pubitemid 44454098)
9. Tsung, A.; Klune, J. R.; Zhang, X.; Jeyabalan, G.; Cao, Z.; Peng, X., et al. HMGB1 release induced by liver ischemia involves Toll-like receptor 4 dependent reactive oxygen species production and calcium-mediated signaling. J. Exp. Med 204: 2913-2923; 2007. (Pubitemid 350179560)
10. Hollingshead, D.; Lewis, D. A.; Mirnics, K. Platform influence on DNA micro-array data in postmortem brain research. Neurobiol. Dis 18: 649-655; 2005. (Pubitemid 40332722)
11. Kurella, M.; Hsiao, L. L.; Yoshida, T.; Randall, J. D.; Chow, G.; Sarang, S. S., et al. DNA microarray analysis of complex biologic processes. J. Am. Soc. Nephrol. 12: 1072-1078; 2001. (Pubitemid 32378349)
12. Noordewier, M. O.; Warren, P. V. Gene expression microarrays and the integration of biological knowledge. Trends Biotechnol 19: 412-415; 2001. (Pubitemid 32925035)
13. Edmonds, R. D.; Vodovotz, Y.; Lagoa, C.; Dutta-Moscato, J.; Yang, Y.; Fink, M. P., et al. Transcriptomic response of murine liver to severe injury and hemor-rhagic shock: a dual-platform microarray analysis. Physiol. Genomics 43: 1170-1183; 2011.
14. Takatsuna, H.; Kato, H.; Gohda, J.; Akiyama, T.; Moriya, A.; Okamoto, Y., et al. Identification of TIFA as an adapter protein that links tumor necrosis factor receptor-associated factor 6 (TRAF6) to interleukin-1 (IL-1) receptor-associated kinase-1 (IRAK-1) in IL-1 receptor signaling. J. Biol. Chem 278: 12144-12150; 2003. (Pubitemid 36800193)
15. Namas, R. A.; Metukuri, M. R.; Dhupar, R.; Velosa, C.; Jefferson, B. S.; Myer, E., et al. Hypoxia-induced overexpression of BNIP3 is not dependent on hypoxia-inducible factor 1a in mouse hepatocytes. Shock 36: 196-202; 2011.
16. Kanamori, M.; Suzuki, H.; Saito, R.; Muramatsu, M.; T2BP, Hayashizaki Y. a novel TRAF2 binding protein, can activate NF-κB and AP-1 without TNF stimulation. Biochem. Biophys. Res. Commun 290: 110 8 -1113; 2002. (Pubitemid 34687478)
17. Rothe, M.; Wong, S. C.; Henzel, W. J.; Goeddel, D. V. A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor. Cell 78: 681-692; 1994. (Pubitemid 24268590)
18. Cao, Z.; Xiong, J.; Takeuchi, M.; Kurama, T.; Goeddel, D. V. TRAF6 is a signal transducer for interleukin-1. Nature 383: 443-446; 1996. (Pubitemid 26330834)
19. Ishida, T.; Mizushima, S.; Azuma, S.; Kobayashi, N.; Tojo, T.; Suzuki, K., et al. Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region. J. Biol. Chem 271: 28745-28748; 1996. (Pubitemid 26382567)
20. Inoue, J.; Ishida, T.; Tsukamoto, N.; Kobayashi, N.; Naito, A.; Azuma, S., et al. Tumor necrosis factor receptor-associated factor (TRAF) family: adapter proteins that mediate cytokine signaling. Exp. Cell Res 254: 14-24; 2000. (Pubitemid 30066727)
21. Wu, H.; TRAF6, Arron J. R. a molecular bridge spanning adaptive immunity, innate immunity and osteoimmunology. BioEssays 25: 1096-1105; 2003. (Pubitemid 37411769)
22. Minoda, Y.; Saeki, K.; Aki, D.; Takaki, H.; Sanada, T.; Koga, K., et al. A novel zinc finger protein, ZCCHC11, interacts with TIFA and modulates TLR signaling. Biochem. Biophys. Res. Commun. 344: 1023-1030; 2006.
23. Sato, S.; Sugiyama, M.; Yamamoto, M.; Watanabe, Y.; Kawai, T.; Takeda, K., et al. Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3, in the Toll-like receptor signaling. J. Immunol 17 1 : 4304-4310; 2003. (Pubitemid 37238709)
24. Koppe, E.; Medzhitov, R. Recognition of microbial infection by Toll-like receptors. Curr. Opin. Immunol. 15: 396-401; 2003. (Pubitemid 36930075)
25. Prince, J. M.; Levy, R. M.; Yang, R.; Mollen, K. P.; Fink, M. P.; Vodovotz, Y., et al. Toll-like receptor-4 signaling mediates hepatic injury and systemic inflammation in hemorrhagic shock. J. Am. Coll. Surg. 202: 407-417; 2006. (Pubitemid 43356214)
26. Frink, M.; Ya-Ching, H.; Thobe, B. M.; Choudhry, M. A.; Schwacha, M. G.; Bland, K. I., et al. TLR4 regulates Kupffer cell chemokine production, systemic inflammation and lung neutrophil infiltration following trauma-hemorrhage. Mol. Immunol. 44: 2625-2630; 2007. (Pubitemid 46240323)
27. Matsumura, T.; Kawamura-Tsuzuku, J.; Yamamoto, T.; Semba, K.; Inoue, J. TRAF-interacting protein with a forkhead-associated domain B (TIFAB) is a negative regulator of the TRAF6-induced cellular functions. J. Biochem 146: 375-381; 2009.
28. Ea, C. K.; Sun, L.; Inoue, J.; Chen, Z. J. TIFA activates IkappaB kinase (IKK) by promoting oligomerization and ubiquitination of TRAF6. Proc. Natl. Acad. Sci. USA 101; 2004. 15318-15223.