-
2
-
-
84857913363
-
Latest Advances and Current Challenges in the Treatment of Multiple Myeloma
-
Mahindra A., Laubach J., Raje N., Munshi N., Richardson P. G., Anderson K.. Latest Advances and Current Challenges in the Treatment of Multiple Myeloma. Nat. Rev. Clin. Oncol. 2012 ; 9: 135-143
-
(2012)
Nat. Rev. Clin. Oncol
, vol.9
, pp. 135-143
-
-
Mahindra, A.1
Laubach, J.2
Raje, N.3
Munshi, N.4
Richardson, P.G.5
Anderson, K.6
-
3
-
-
0035102346
-
The Bone Marrow Stromal Microenvironment Influences Myeloma Therapeutic Response in Vitro
-
Cheung W. C., Van Ness B.. The Bone Marrow Stromal Microenvironment Influences Myeloma Therapeutic Response In Vitro. Leukemia. 2001 ; 15: 264-271
-
(2001)
Leukemia
, vol.15
, pp. 264-271
-
-
Cheung, W.C.1
Van Ness, B.2
-
4
-
-
58249120680
-
Bortezomib Overcomes Cell-Adhesion-Mediated Drug Resistance through Downregulation of VLA-4 Expression in Multiple Myeloma
-
Noborio-Hatano K., Kikuchi J., Takatoku M., Shimizu R., Wada T., Ueda M., Nobuyoshi M., Oh I., Sato K., Suzuki T., Ozaki K., Mori M., Nagai T., Muroi K., Kano Y., Furukawa Y., Ozawa K.. Bortezomib Overcomes Cell-Adhesion-Mediated Drug Resistance through Downregulation of VLA-4 Expression in Multiple Myeloma. Oncogene. 2009 ; 28: 231-242
-
(2009)
Oncogene
, vol.28
, pp. 231-242
-
-
Noborio-Hatano, K.1
Kikuchi, J.2
Takatoku, M.3
Shimizu, R.4
Wada, T.5
Ueda, M.6
Nobuyoshi, M.7
Oh, I.8
Sato, K.9
Suzuki, T.10
Ozaki, K.11
Mori, M.12
Nagai, T.13
Muroi, K.14
Kano, Y.15
Furukawa, Y.16
Ozawa, K.17
-
5
-
-
40749116017
-
Bone Marrow Stroma Confers Resistance to Apo2 Ligand/TRAIL in Multiple Myeloma in Part by Regulating c-FLIP
-
Perez L. E., Parquet N., Shain K., Nimmanapalli R., Alsina M., Anasetti C., Dalton W.. Bone Marrow Stroma Confers Resistance to Apo2 Ligand/TRAIL in Multiple Myeloma in Part by Regulating c-FLIP. J. Immunol. 2008 ; 180: 1545-1555
-
(2008)
J. Immunol
, vol.180
, pp. 1545-1555
-
-
Perez, L.E.1
Parquet, N.2
Shain, K.3
Nimmanapalli, R.4
Alsina, M.5
Anasetti, C.6
Dalton, W.7
-
6
-
-
52049103847
-
The Bone Marrow Microenvironment as a Tumor Sanctuary and Contributor to Drug Resistance
-
Meads M. B., Hazlehurst L. A., Dalton W. S.. The Bone Marrow Microenvironment as a Tumor Sanctuary and Contributor to Drug Resistance. Clin. Cancer Res. 2008 ; 14: 2519-2526
-
(2008)
Clin. Cancer Res
, vol.14
, pp. 2519-2526
-
-
Meads, M.B.1
Hazlehurst, L.A.2
Dalton, W.S.3
-
7
-
-
0038717067
-
Bone Marrow Stromal-Derived Soluble Factors and Direct Cell Contact Contribute to de Novo Drug Resistance of Myeloma Cells by Distinct Mechanisms
-
Nefedova Y., Landowski T. H., Dalton W. S.. Bone Marrow Stromal-Derived Soluble Factors and Direct Cell Contact Contribute to De Novo Drug Resistance of Myeloma Cells by Distinct Mechanisms. Leukemia. 2003 ; 17: 1175-1182
-
(2003)
Leukemia
, vol.17
, pp. 1175-1182
-
-
Nefedova, Y.1
Landowski, T.H.2
Dalton, W.S.3
-
8
-
-
84859169877
-
The Cancer Cell Line Encyclopedia Enables Predictive Modelling of Anticancer Drug Sensitivity
-
Barretina J., Caponigro G., Stransky N., Venkatesan K., Margolin A. A., Kim S., Wilson C. J., Lehar J., Kryukov G. V., Sonkin D., et al. The Cancer Cell Line Encyclopedia Enables Predictive Modelling of Anticancer Drug Sensitivity. Nature. 2012 ; 483: 603-607
-
(2012)
Nature
, vol.483
, pp. 603-607
-
-
Barretina, J.1
Caponigro, G.2
Stransky, N.3
Venkatesan, K.4
Margolin, A.A.5
Kim, S.6
Wilson, C.J.7
Lehar, J.8
Kryukov, G.V.9
Sonkin, D.10
-
9
-
-
84859187259
-
Systematic Identification of Genomic Markers of Drug Sensitivity in Cancer Cells
-
Garnett M. J., Edelman E. J., Heidorn S. J., Greenman C. D., Dastur A., Lau K. W., Greninger P., Thompson I. R., Luo X., Soares J., et al. Systematic Identification of Genomic Markers of Drug Sensitivity in Cancer Cells. Nature. 2012 ; 483: 570-575
-
(2012)
Nature
, vol.483
, pp. 570-575
-
-
Garnett, M.J.1
Edelman, E.J.2
Heidorn, S.J.3
Greenman, C.D.4
Dastur, A.5
Lau, K.W.6
Greninger, P.7
Thompson, I.R.8
Luo, X.9
Soares, J.10
-
10
-
-
84860839794
-
Fluorescence-Based Experimental Model to Evaluate the Concomitant Effect of Drugs on the Tumour Microenvironment and Cancer Cells
-
Ramasamy K., Khatun H., Macpherson L., Caley M. P., Sturge J., Mufti G. J., Schey S. A., Calle Y.. Fluorescence-Based Experimental Model to Evaluate the Concomitant Effect of Drugs on the Tumour Microenvironment and Cancer Cells. Br. J. Haematol. 2012 ; 157: 564-579
-
(2012)
Br. J. Haematol
, vol.157
, pp. 564-579
-
-
Ramasamy, K.1
Khatun, H.2
Macpherson, L.3
Caley, M.P.4
Sturge, J.5
Mufti, G.J.6
Schey, S.A.7
Calle, Y.8
-
11
-
-
77950542260
-
Tumor Cell-Specific Bioluminescence Platform to Identify Stroma-Induced Changes to Anticancer Drug Activity
-
McMillin D. W., Delmore J., Weisberg E., Negri J. M., Geer D. C., Klippel S., Mitsiades N., Schlossman R. L., Munshi N. C., Kung A. L., et al. Tumor Cell-Specific Bioluminescence Platform to Identify Stroma-Induced Changes to Anticancer Drug Activity. Nat. Med. 2010 ; 16: 483-489
-
(2010)
Nat. Med
, vol.16
, pp. 483-489
-
-
McMillin, D.W.1
Delmore, J.2
Weisberg, E.3
Negri, J.M.4
Geer, D.C.5
Klippel, S.6
Mitsiades, N.7
Schlossman, R.L.8
Munshi, N.C.9
Kung, A.L.10
-
12
-
-
84866552319
-
Addiction to c-MYC in Multiple Myeloma
-
Holien T., Vatsveen T. K., Hella H., Waage A., Sundan A.. Addiction to c-MYC in Multiple Myeloma. Blood. 2012 ; 120: 2450-2453
-
(2012)
Blood
, vol.120
, pp. 2450-2453
-
-
Holien, T.1
Vatsveen, T.K.2
Hella, H.3
Waage, A.4
Sundan, A.5
-
13
-
-
84858022172
-
Microscale Functional Cytomics for Studying Hematologic Cancers
-
Young E. W., Pak C., Kahl B. S., Yang D. T., Callander N. S., Miyamoto S., Beebe D. J.. Microscale Functional Cytomics for Studying Hematologic Cancers. Blood. 2012 ; 119: e76 - e85
-
(2012)
Blood
, vol.119
-
-
Young, E.W.1
Pak, C.2
Kahl, B.S.3
Yang, D.T.4
Callander, N.S.5
Miyamoto, S.6
Beebe, D.J.7
-
14
-
-
0242458219
-
A Microscope-Based Screening Platform for Large-Scale Functional Protein Analysis in Intact Cells
-
Liebel U., Starkuviene V., Erfle H., Simpson J. C., Poustka A., Wiemann S., Pepperkok R.. A Microscope-Based Screening Platform for Large-Scale Functional Protein Analysis in Intact Cells. FEBS Lett. 2003 ; 554: 394-398
-
(2003)
FEBS Lett
, vol.554
, pp. 394-398
-
-
Liebel, U.1
Starkuviene, V.2
Erfle, H.3
Simpson, J.C.4
Poustka, A.5
Wiemann, S.6
Pepperkok, R.7
-
15
-
-
61649096564
-
Establishment of a High Content Assay for the Identification and Characterisation of Bioactivities in Crude Bacterial Extracts That Interfere with the Eukaryotic Cell Cycle
-
Jensen N. A., Gerth K., Grotjohann T., Kapp D., Keck M., Niehaus K.. Establishment of a High Content Assay for the Identification and Characterisation of Bioactivities in Crude Bacterial Extracts That Interfere with the Eukaryotic Cell Cycle. J. Biotechnol. 2009 ; 140: 124-134
-
(2009)
J. Biotechnol
, vol.140
, pp. 124-134
-
-
Jensen, N.A.1
Gerth, K.2
Grotjohann, T.3
Kapp, D.4
Keck, M.5
Niehaus, K.6
-
17
-
-
0031929051
-
The Myeloma Cell Antigen Syndecan-1 Is Lost by Apoptotic Myeloma Cells
-
Jourdan M., Ferlin M., Legouffe E., Horvathova M., Liautard J., Rossi J. F., Wijdenes J., Brochier J., Klein B.. The Myeloma Cell Antigen Syndecan-1 Is Lost by Apoptotic Myeloma Cells. Br. J. Haematol. 1998 ; 100: 637-646
-
(1998)
Br. J. Haematol
, vol.100
, pp. 637-646
-
-
Jourdan, M.1
Ferlin, M.2
Legouffe, E.3
Horvathova, M.4
Liautard, J.5
Rossi, J.F.6
Wijdenes, J.7
Brochier, J.8
Klein, B.9
-
18
-
-
0036839144
-
In the Presence of Bone Marrow Stromal Cells Human Multiple Myeloma Cells Become Independent of the IL-6/gp130/STAT3 Pathway
-
Chatterjee M., Honemann D., Lentzsch S., Bommert K., Sers C., Herrmann P., Mathas S., Dorken B., Bargou R. C.. In the Presence of Bone Marrow Stromal Cells Human Multiple Myeloma Cells Become Independent of the IL-6/gp130/STAT3 Pathway. Blood. 2002 ; 100: 3311-3318
-
(2002)
Blood
, vol.100
, pp. 3311-3318
-
-
Chatterjee, M.1
Honemann, D.2
Lentzsch, S.3
Bommert, K.4
Sers, C.5
Herrmann, P.6
Mathas, S.7
Dorken, B.8
Bargou, R.C.9
-
19
-
-
79951494668
-
Initial Genome Sequencing and Analysis of Multiple Myeloma
-
Chapman M. A., Lawrence M. S., Keats J. J., Cibulskis K., Sougnez C., Schinzel A. C., Harview C. L., Brunet J. P., Ahmann G. J., Adli M., et al. Initial Genome Sequencing and Analysis of Multiple Myeloma. Nature. 2011 ; 471: 467-472
-
(2011)
Nature
, vol.471
, pp. 467-472
-
-
Chapman, M.A.1
Lawrence, M.S.2
Keats, J.J.3
Cibulskis, K.4
Sougnez, C.5
Schinzel, A.C.6
Harview, C.L.7
Brunet, J.P.8
Ahmann, G.J.9
Adli, M.10
-
20
-
-
84864561961
-
Whole Genome Sequencing of Multiple Myeloma from Diagnosis to Plasma Cell Leukemia Reveals Genomic Initiating Events, Evolution and Clonal Tides
-
Egan J. B., Shi C. X., Tembe W., Christoforides A., Kurdoglu A., Sinari S., Middha S., Asmann Y., Schmidt J., Braggio E., et al. Whole Genome Sequencing of Multiple Myeloma from Diagnosis to Plasma Cell Leukemia Reveals Genomic Initiating Events, Evolution and Clonal Tides. Blood. 2012 ; 120: 1060-1066
-
(2012)
Blood
, vol.120
, pp. 1060-1066
-
-
Egan, J.B.1
Shi, C.X.2
Tembe, W.3
Christoforides, A.4
Kurdoglu, A.5
Sinari, S.6
Middha, S.7
Asmann, Y.8
Schmidt, J.9
Braggio, E.10
-
22
-
-
79955843637
-
Molecular Heterogeneity of Multiple Myeloma: Pathogenesis, Prognosis, and Therapeutic Implications
-
Avet-Loiseau H., Magrangeas F., Moreau P., Attal M., Facon T., Anderson K., Harousseau J., N. M., S. M. Molecular Heterogeneity of Multiple Myeloma: Pathogenesis, Prognosis, and Therapeutic Implications. J. Clin. Oncol. 2011 ; 29: 1893-1897
-
(2011)
J. Clin. Oncol
, vol.29
, pp. 1893-1897
-
-
Avet-Loiseau, H.1
Magrangeas, F.2
Moreau, P.3
Attal, M.4
Facon, T.5
Anderson, K.6
Harousseau, J.7
-
23
-
-
4944230728
-
Osteoclasts Enhance Myeloma Cell Growth and Survival via Cell-Cell Contact: A Vicious Cycle between Bone Destruction and Myeloma Expansion
-
Abe M., Hiura K., Wilde J., Shioyasono A., Moriyama K., Hashimoto T., Kido S., Oshima T., Shibata H., Ozaki S., et al. Osteoclasts Enhance Myeloma Cell Growth and Survival via Cell-Cell Contact: A Vicious Cycle between Bone Destruction and Myeloma Expansion. Blood. 2004 ; 104: 2484-2491
-
(2004)
Blood
, vol.104
, pp. 2484-2491
-
-
Abe, M.1
Hiura, K.2
Wilde, J.3
Shioyasono, A.4
Moriyama, K.5
Hashimoto, T.6
Kido, S.7
Oshima, T.8
Shibata, H.9
Ozaki, S.10
-
24
-
-
84863812218
-
Macrophages and Mesenchymal Stromal Cells Support Survival and Proliferation of Multiple Myeloma Cells
-
Kim J., Denu R. A., Dollar B. A., Escalante L. E., Kuether J. P., Callander N. S., Asimakopoulos F., Hematti P.. Macrophages and Mesenchymal Stromal Cells Support Survival and Proliferation of Multiple Myeloma Cells. Br. J. Haematol. 2012 ; 158: 336-346
-
(2012)
Br. J. Haematol
, vol.158
, pp. 336-346
-
-
Kim, J.1
Denu, R.A.2
Dollar, B.A.3
Escalante, L.E.4
Kuether, J.P.5
Callander, N.S.6
Asimakopoulos, F.7
Hematti, P.8
-
25
-
-
70449477633
-
Macrophages are an Abundant Component of Myeloma Microenvironment and Protect Myeloma Cells from Chemotherapy Drug-Induced Apoptosis
-
Zheng Y., Cai Z., Wang S., Zhang X., Qian J., Hong S., Li H., Wang M., Yang J., Yi Q.. Macrophages are an Abundant Component of Myeloma Microenvironment and Protect Myeloma Cells from Chemotherapy Drug-Induced Apoptosis. Blood. 2009 ; 114: 3625-3628
-
(2009)
Blood
, vol.114
, pp. 3625-3628
-
-
Zheng, Y.1
Cai, Z.2
Wang, S.3
Zhang, X.4
Qian, J.5
Hong, S.6
Li, H.7
Wang, M.8
Yang, J.9
Yi, Q.10
|