The Putative Protein Methyltransferase LAE1 of Trichoderma atroviride Is a Key Regulator of Asexual Development and Mycoparasitism

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Aghcheh, Razieh Karimi ^a   Druzhinina, Irina S ^a   Kubicek, Christian P ^a  

^a VIENNA UNIVERSITY OF TECHNOLOGY   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLUCAN HYDROLASE; CYSTEIN RICH SECRETED PROTEIN; FUNGAL PROTEIN; METHYLTRANSFERASE; POLYKETIDE SYNTHASE; PROTEIN LAE1; PROTEINASE; UNCLASSIFIED DRUG;

ARTICLE; ASEXUAL REPRODUCTION; CELL DAMAGE; CONTROLLED STUDY; DARKNESS; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME REGULATION; FUNGAL METABOLISM; FUNGAL STRAIN; GENE DELETION; GENE OVEREXPRESSION; IMMUNITY; LAE1 GENE; LOSS OF FUNCTION MUTATION; MYCELIUM; MYCOPARASITISM; NONHUMAN; OXIDATIVE STRESS; PHOTOSTIMULATION; PROTEIN DEPLETION; SPOROGENESIS; TRICHODERMA; TRICHODERMA ATROVIRIDE;

ANIMALS; ANTIFUNGAL AGENTS; CARBON; CELLULASE; DARKNESS; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; HYDROGEN PEROXIDE; METHYLTRANSFERASES; MOLECULAR SEQUENCE DATA; MUTATION; OXIDATIVE STRESS; PARASITES; PHENOTYPE; RECEPTOR CROSS-TALK; REPRODUCTION, ASEXUAL; SEQUENCE HOMOLOGY, AMINO ACID; SPORES, FUNGAL; STRESS, MECHANICAL; TRICHODERMA; VOLATILE ORGANIC COMPOUNDS;

ASCOMYCOTA; FUNGI; TRICHODERMA ATROVIRIDE;

EID: 84879470049     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0067144     Document Type: Article

References (40)

1. Druzhinina IS, Seidl-Seiboth V, Herrera-Estrella A, Horwitz BA, Kenerley CM, et al. (2011) Trichoderma: the genomics of opportunistic success. Nature Reviews Microbiology 16: 749-759.
2. Verma M, Brar SK, Tyagi RD, Surampalli RY, Val'ero RJ, (2007) Antagonistic fungi, Trichoderma spp.: panoply of biological control. Biochem Eng. J. 37: 1-20.
3. Kubicek CP, Herrera-Estrella A, Seidl-Seiboth V, Le Crom S, Martinez DA, et al. (2011) Comparative genome sequence analysis underscores mycoparasitism as the ancestral life style of Trichoderma. Genome Biology 12: R40.
4. Harman GE, Howell CR, Viterbo A, Chet I, Lorito M, (2004) Trichoderma species- opportunistic, avirulent plant symbionts. Nature Reviews Microbiology 2: 43-56.
5. Omann M, Zeilinger S, (2010) How a mycoparasite employs g-protein signaling: using the example of Trichoderma. J Signal Transduct 2010: 123-126.
6. Mukherjee PK, Kenerley CM, (2010) Regulation of morphogenesis and biocontrol properties in Trichoderma virens by a VELVET protein, Vel1. Appl Environ Microbiol. 76: 2345-1052.
7. Calvo AM, (2008) The VeA regulatory system and its role in morphological and chemical development in fungi. Fungal Genet Biol. 45: 1053-1061.
8. Bayram O, Braus GH, (2012) Coordination of secondary metabolism and development in fungi: the velvet family of regulatory proteins. FEMS Microbiol Rev. 36: 1-24.
9. Bayram O, Krappmann S, Ni M, Bok JW, Helmstaedt K, et al. (2008) VelB/VeA/LaeA Complex Coordinates Light Signal with Fungal Development and Secondary Metabolism. Science 320: 1504-1506.
10. Bok JW, Keller NP, (2004) LaeA, a regulator of secondary metabolism in Aspergillus spp. Eukaryot Cell 3: 527-535.
11. Bok JW, Chiang YM, Szewczyk E, Reyes-Dominguez Y, Davidson AD, et al. (2009) Chromatin-level regulation of biosynthetic gene clusters. Nat Chem Biol. 5: 462-464.
12. Hoff B, Kamerewerd J, Sig IC, Mitterbauer R, Zadra I, et al. (2010) Two components of a velvet-like complex control hyphal morphogenesis, conidiophore development, and penicillin biosynthesis in Penicillium chrysogenum. Eukaryot Cell 9: 1236-1250.
13. Wiemann P, Brown DW, Kleigrewe K, Bok JW, Keller NP, et al. (2010) FfVel1 and FfLae1, components of a velvet-like complex in Fusarium fujikuroi, affect differentiation, secondary metabolism and virulence. Mol Microbiol. 7: 972-994.
14. Wu D, Oide S, Zhang N, Choi MY, Turgeon BG, (2012) ChLae1 and ChVel1 regulate T-toxin production, virulence, oxidative stress response, and development of the maize pathogen Cochliobolus heterostrophus. PLoS Pathog. 8: e1002542.
15. Butchko RA, Brown DW, Busman M, Tudzynski B, Wiemann P, (2012) Lae1 regulates expression of multiple secondary metabolite gene clusters in Fusarium verticillioides. Fungal Genet Biol. 49: 602-612.
16. Bok JW, Balajee SA, Marr KA, Andes D, Nielsen KF, et al. (2005) LaeA, a regulator of morphogenetic fungal virulence factors. Eukaryot Cell 4: 1574-1582.
17. Sugui Ja, Pardo J, Chang YC, Müllbacher A, Zarember KA, et al. (2007) Role of laeA in the Regulation of alb1, gliP, Conidial Morphology, and Virulence in Aspergillus fumigatus. Eukaryot Cell. 6: 1552-1561.
18. Seiboth B, Karimi-Aghcheh R, Phatale PA, Linke R, Hartl L, et al. (2012) The putative protein methyltransferase LAE1 controls cellulase gene expression in Trichoderma reesei. Mol Microbiol. 84: 1150-1164.
19. Karimi-Aghcheh R, Bok JW, Phatale PA, Smith KM, Baker SE, et al. (2013) Functional analyses of Trichoderma reesei LAE1 reveal conserved and contrasting roles of this regulator. G3 3: 369-378.
20. Kullnig CM, Krupica T, Woo SL, Mach RL, Rey M, et al. (2001) Confusion abounds over identity of Trichoderma biocontrol isolates. Mycol Res 105: 769-772.
21. Casas-Flores S, Rios-Momberg M, Bibbins M, Ponce-Noyola P, Herrera-Estrella A, (2004) BLR-1 and BLR-2, key regulatory elements of photoconidiation and mycelial growth in Trichoderma atroviride. Microbiology 150: 3561-3569.
22. Mach RL, Schindler M, Kubicek CP, (1994) Transformation of Trichoderma reesei based on hygromycin resistance using homologous expression signals. Curr Genet 25: 567-570.
23. Akel E, Metz B, Seiboth B, Kubicek CP, (2009) Molecular regulation of arabinan and L-arabinose metabolism in Hypocrea jecorina (Trichoderma reesei). Eukaryot Cell 8: 1837-1844.
24. Guangtao Z, Hartl L, Schuster A, Polak S, Schmoll M, et al. (2009) Gene targeting in a nonhomologous end joining deficient Hypocrea jecorina. J Biotechnol 139: 146-151.
25. Friedl MA, Schmoll M, Kubicek CP, Druzhinina IS, (2008) Photostimulation of Hypocrea atroviridis growth occurs due to a cross-talk of carbon metabolism, blue light receptors and response to oxidative stress. Microbiology UK 154: 1229-1241.
26. Atanasova L, Le Crom S, Gruber S, Coulpier F, Seidl-Seiboth V, et al. (2012) Comparative transcriptomics reveals versatile strategies of Trichoderma mycoparasitism. BMC Genomics 14: 121.
27. Mandels M, Andreotti RE, (1978) Problems and challenges in the cellulose to cellulase fermentation. Process Biochem 13: 6-13.
28. Pfaffl MW, Horgan GW, Dempfle LD, (2002) Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res 30: e36.
29. Nemcovic M, Jakubíková L, Víden I, Farkas V, (2008) Induction of conidiation by endogenous volatile compounds in Trichoderma spp. FEMS Microbiol Lett 284: 231-236.
30. Steyaert JM, Weld RJ, Mendoza-Mendoza A, Stewart A, (2010) Reproduction without sex: conidiation in the filamentous fungus Trichoderma. Microbiology 156: 2887-2900.
31. Carreras-Villaseñor N, Sánchez-Arreguín JA, Herrera-Estrella AH, (2012) Trichoderma: sensing the environment for survival and dispersal. Microbiology 158: 3-16.
32. Hernández-Oñate MA, Esquivel-Naranjo EU, Mendoza-Mendoza A, Stewart A, Herrera-Estrella AH, (2012) An injury-response mechanism conserved across kingdoms determines entry of the fungus Trichoderma atroviride into development. Proc Natl Acad Sci U S A. 109: 14918-14923.
33. Reino JL, Guerrero RF, Hernández-Galan I, Collado IG, (2008) Secondary metabolites from species of the biocontrol agent Trichoderma. Phytochem Rev 7: 89-123.
34. Claydon N, Allan M, Hanson JR, Avent AG, (1987) Antifungal alkylpyrones from Trichoderma harzianum. Trans Br Mycol Soc 88: 503-513.
35. Chang PK, Scharfenstein LL, Ehrlich KC, Wie Q, Bhatnagar D, et al. (2012) Effects of laeA deletion on Aspergillus flavus conidial development and hydrophobicity may contribute to loss of aflatoxin production. Fungal Biol 116: 298-307.
36. Druzhinina IS, Komoń-Zelazowska M, Atanasova L, Seidl V, Kubicek CP, (2010) Evolution and ecophysiology of the industrial producer Hypocrea jecorina (Anamorph Trichoderma reesei) and a new sympatric agamospecies related to it. PLoS One 5: e9191.
37. Friedl MA, Kubicek CP, Druzhinina IS, (2008) Carbon source dependence and photostimulation of conidiation in Hypocrea atroviridis. Appl Environ Microbiol. 74: 245-250.
38. Roze LV, Chanda A, Laivenieks M, Beaudry RM, Artymovich KA, et al. (2010) Volatile profiling reveals intracellular metabolic changes in Aspergillus parasiticus: veA regulates branched chain amino acid and ethanol metabolism. BMC Biochem. 24 11: 33.
39. Sarikaya Bayram O, Bayram O, Valerius O, Park HS, Irniger S, et al. (2010) LaeA control of velvet family regulatory proteins for light-dependent development and fungal cell-type specificity. PLoS Genet. 6: e1001226.
40. Schrey AW, Richards CL, (2012) Within-genotype epigenetic variation enables broad niche width in a flower living yeast. Mol Ecol. 21: 2559-2561.