Follicular lymphoma in Taiwan: A low frequency of t(14;18), with grade 3A tumours more closely related to grade 3B than to low-grade tumours

Histopathology

Volumn 63, Issue 1, 2013, Pages 1-12

  Chang, Sheng Tsung ^a,b   Lu, Yi Hsuan ^c   Lu, Chin Li ^a   Kuo, Szu Yin ^a   Liu, Hongxiang ^d   Lin, Shu Hui ^a   Win, Khin Than ^a   Hsieh, Yen Chuan ^a   Chuang, Shih Sung ^a,e  

^a Chi Mei Medical Centre   (Taiwan)

^b NATIONAL TAINAN INSTITUTE OF NURSING   (Taiwan)

^c CHI MEI MEDICAL CENTER   (Taiwan)

^d ADDENBROOKE S HOSPITAL   (United Kingdom)

^e NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

BCL2; Fluorescence in situ hybridization; Follicular lymphoma; T(14; 18); Taiwan

Indexed keywords

COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGEN; IMMUNOGLOBULIN HEAVY CHAIN; INTERFERON REGULATORY FACTOR 4; MYC PROTEIN; PROTEIN BCL 2; PROTEIN BCL 6;

ADULT; AGED; ARTICLE; CANCER SURVIVAL; CANCER TISSUE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; FOLLICULAR LYMPHOMA; FUSION GENE; GENE FREQUENCY; GENE REARRANGEMENT; GENE TRANSLOCATION; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; MALE; PHENOTYPE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; TAIWAN;

CHROMOSOMES, HUMAN, PAIR 14; CHROMOSOMES, HUMAN, PAIR 18; FEMALE; GENE FREQUENCY; HUMANS; IMMUNOPHENOTYPING; IN SITU HYBRIDIZATION, FLUORESCENCE; LYMPHOMA, FOLLICULAR; LYMPHOMA, LARGE B-CELL, DIFFUSE; MALE; MIDDLE AGED; NEOPLASM GRADING; PROTO-ONCOGENE PROTEINS C-BCL-2; RETROSPECTIVE STUDIES; TAIWAN; TRANSLOCATION, GENETIC;

EID: 84879464058     PISSN: 03090167     EISSN: 13652559     Source Type: Journal    
DOI: 10.1111/his.12119     Document Type: Article

References (55)

1. Anderson JR, Armitage JO, Weisenburger DD. Epidemiology of the non-Hodgkin's lymphomas: distributions of the major subtypes differ by geographic locations. Non-
2. Lee SS, Cho KJ, Kim CW et al. Clinicopathological analysis of 501 non-Hodgkin's lymphomas in Korea according to the revised European-American classification of
3. Pathologists LSGoJ. The World Health Organization classification of malignant lymphomas in Japan: incidence of recently recognized entities. Lymphoma Study Group of
4. Chuang SS, Lin CN, Li CY. Malignant lymphoma in southern Taiwan according to the revised European-American classification of lymphoid neoplasms. Cancer 2000; 89; 1586-1592.
5. Biagi JJ, Seymour JF. Insights into the molecular pathogenesis of follicular lymphoma arising from analysis of geographic variation. Blood 2002; 99; 4265-4275.
6. Harris NL, Swerdlow SH, Jaffe ES et al. Follicular lymphoma. In Swerdlow H, Campo E, Harris NL et al. eds. World Health Organization classification of tumours of haematopoietic and lymphoid tissues. Lyon: IARC Press, 2008; 220-226.
7. Vaandrager JW, Schuuring E, Raap T et al. Interphase FISH detection of BCL2 rearrangement in follicular lymphoma using breakpoint-flanking probes. Genes Chromosom.Cancer 2000; 27; 85-94.
8. Barrans SL, Evans PA, O'Connor SJ et al. The detection of t (14;18) in archival lymph nodes: development of a fluorescence in situ hybridization (FISH)-based method and evaluation by comparison with polymerase chain reaction. J. Mol. Diagn. 2003; 5; 168-175.
9. Fan YS, Rizkalla K. Comprehensive cytogenetic analysis including multicolor spectral karyotyping and interphase fluorescence in situ hybridization in lymphoma
10. Godon A, Moreau A, Talmant P et al. Is t(14;18)(q32;q21) a constant finding in follicular lymphoma? An interphase FISH study on 63 patients. Leukemia 2003; 17; 255-259.
11. Belaud-Rotureau MA, Parrens M, Carrere N et al. Interphase fluorescence in situ hybridization is more sensitive than BIOMED-2 polymerase chain reaction protocol in lymphoma. Hum. Pathol. 2007; 38; 365-372.
12. Weinberg OK, Ai WZ, Mariappan MR et al. 'Minor' BCL2 breakpoints in follicular lymphoma: frequency and correlation with grade and disease presentation in 236 cases. J. Mol. Diagn. 2007; 9; 530-537.
13. Espinet B, Bellosillo B, Melero C et al. FISH is better than BIOMED-2 PCR to detect IgH/BCL2 translocation in follicular lymphoma at diagnosis using paraffin-
14. Chang CM, Schroeder JC, Huang WY et al. Non-Hodgkin lymphoma (NHL) subtypes defined by common translocations: utility of fluorescence in situ hybridization (FISH)
15. Payne K, Wright P, Grant JW et al. BIOMED-2 PCR assays for IGK gene rearrangements are essential for B-cell clonality analysis in follicular lymphoma. Br.J. Haematol. 2011; 155; 84-92.
16. Bosga-Bouwer AG, van Imhoff GW, Boonstra R et al. Follicular lymphoma grade 3B includes 3 cytogenetically defined subgroups with primary t (14;18), 3q27, or other
17. Ott G, Katzenberger T, Lohr A et al. Cytomorphologic, immunohistochemical, and cytogenetic profiles of follicular lymphoma: 2 types of follicular lymphoma grade 3.
18. Horn H, Schmelter C, Leich E et al. Follicular lymphoma grade 3B is a distinct neoplasm according to cytogenetic and immunohistochemical profiles. Haematologica 2011;
19. Lee MY, Tan TD, Feng AC et al. Clinicopathological analysis of malignant lymphoma in Taiwan, defined according to the World Health Organization classification.
20. Chuang SS. Significant increase in the relative frequency of follicular lymphoma in Taiwan in the early 21st century. J. Clin. Pathol. 2008; 61; 879-880.
21. Aoki R, Karube K, Sugita Y et al. Distribution of malignant lymphoma in Japan: analysis of 2260 cases, 2001-2006. Pathol. Int. 2008; 58; 174-182.
22. Miura Y, Fukuhara N, Yamamoto J et al. Clinicopathological features of malignant lymphoma in Japan: the Miyagi Study. Tohoku J. Exp. Med. 2011; 224; 151-160.
23. Chuang SS, Hsieh PP, Lu CL et al. A clinicopathologic and molecular study of follicular lymphoma in Taiwan. Clin. Lymphoma Myeloma 2006; 6; 314-318.
24. Einerson RR, Kurtin PJ, Dayharsh GA et al. FISH is superior to PCR in detecting t(14;18)(q32;q21)-IgH/bcl-2 in follicular lymphoma using paraffin-embedded tissue samples. Am. J. Clin. Pathol. 2005; 124; 421-429.
25. Baro C, Espinet B, Salido M et al. Cryptic IGH/BCL2 rearrangements with variant FISH patterns in follicular lymphoma. Leuk. Res. 2011; 35; 256-259.
26. Chuang SS, Ye H, Yang SF et al. Perforation predicts poor prognosis in patients with primary intestinal diffuse large B-cell lymphoma. Histopathology 2008; 53; 432-440.
27. Guo Y, Karube K, Kawano R et al. Low-grade follicular lymphoma with t(14;18) presents a homogeneous disease entity otherwise the rest comprises minor groups of heterogeneous disease entities with Bcl2 amplification, Bcl6 translocation or other gene aberrances. Leukemia 2005; 19; 1058-1063.
28. Lee D, Seo J, Oh Y et al. Analysis of follicular lymphoma by dual-color fluorescence in situ hybridization. Virchows Arch. 2008; 452; 75-81.
29. Matsumoto Y, Nomura K, Matsumoto S et al. Detection of t(14;18) in follicular lymphoma by dual-color fluorescence in situ hybridization on paraffin-embedded tissue
30. Peh SC, Shaminie J, Tai YC et al. The pattern and frequency of t(14;18) translocation and immunophenotype in Asian follicular lymphoma. Histopathology 2004;45; 501-510.
31. Rojnuckarin P, Assanasen T, Chotipuech A et al. High frequency of BCL2 translocation in Thai patients with follicular lymphomas. Int. J. Hematol. 2007; 86; 352-357.
32. Sekiguchi N, Kobayashi Y, Yokota Y et al. Follicular lymphoma subgrouping by fluorescence in situ hybridization analysis. Cancer Sci. 2005; 96; 77-82.
33. Bierman PJ. Natural history of follicular grade 3 non-Hodgkin's lymphoma. Curr. Opin. Oncol. 2007; 19; 433-437.
34. Shustik J, Quinn M, Connors JM et al. Follicular non-Hodgkin lymphoma grades 3A and 3B have a similar outcome and appear incurable with anthracycline-based therapy. Ann. Oncol. 2011; 22; 1164-1169.
35. Accornero P, Lattanzio G, Mangano T et al. An in vivo model of Met-driven lymphoma as a tool to explore the therapeutic potential of Met inhibitors. Clin. Cancer Res. 2008; 14; 2220-2226.
36. Leich E, Salaverria I, Bea S et al. Follicular lymphomas with and without translocation t(14;18) differ in gene expression profiles and genetic alterations. Blood 2009; 114; 826-834.
37. Leich E, Ott G, Rosenwald A. Pathology, pathogenesis and molecular genetics of follicular NHL. Best Pract. Res. Clin. Haematol. 2011; 24; 95-109.
38. Leich E, Zamo A, Horn H et al. MicroRNA profiles of t(14;18)- negative follicular lymphoma support a late germinal center B-cell phenotype. Blood 2011; 118; 5550-5558.
39. Slack GW, Gascoyne RD. MYC and aggressive B-cell lymphomas. Adv. Anat. Pathol. 2011; 18; 219-228.
40. Christie L, Kernohan N, Levison D et al. C-MYC translocation in t(14;18) positive follicular lymphoma at presentation: an adverse prognostic indicator? Leuk. Lymphoma 2008; 49; 470-476.
41. Aukema SM, Siebert R, Schuuring E et al. Double-hit B-cell lymphomas. Blood 2011; 117; 2319-2331.
42. Liu Y, Hernandez AM, Shibata D et al. BCL2 translocation frequency rises with age in humans. Proc. Natl Acad. Sci. USA 1994; 91; 8910-8914.
43. Dolken G, Illerhaus G, Hirt C et al. BCL-2/JH rearrangements in circulating B cells of healthy blood donors and patients with nonmalignant diseases. J. Clin. Oncol. 1996; 14; 1333-1344.
44. Yasukawa M, Bando S, Dolken G et al. Low frequency of BCL- 2/J(H) translocation in peripheral blood lymphocytes of healthy Japanese individuals. Blood 2001; 98; 486-488.
45. Schuler F, Dolken L, Hirt C et al. Prevalence and frequency of circulating t(14;18)-MBR translocation carrying cells in healthy individuals. Int. J. Cancer 2009; 124; 958-963.
46. Katzenberger T, Ott G, Klein T et al. Cytogenetic alterations affecting BCL6 are predominantly found in follicular lymphomas grade 3B with a diffuse large B-cell component. Am. J. Pathol. 2004; 165; 481-490.
47. Cheung KJ, Johnson NA, Affleck JG et al. Acquired TNFRSF14 mutations in follicular lymphoma are associated with worse prognosis. Cancer Res. 2010; 70; 9166-9174.
48. Launay E, Pangault C, Bertrand P et al. High rate of TNFRSF14 gene alterations related to 1p36 region in de novo follicular lymphoma and impact on prognosis. Leukemia 2012; 26; 559-562.
49. Katzenberger T, Kalla J, Leich E et al. A distinctive subtype of t(14;18)-negative nodal follicular non-Hodgkin lymphoma characterized by a predominantly diffuse growth pattern and deletions in the chromosomal region 1p36. Blood 2009; 113; 1053-1061.
50. Karube K, Guo Y, Suzumiya J et al. CD10-MUM1+ follicular lymphoma lacks BCL2 gene translocation and shows characteristic biologic and clinical features. Blood 2007; 109; 3076-3079.
51. Karube K, Ying G, Tagawa H et al. BCL6 gene amplification/ 3q27 gain is associated with unique clinicopathological characteristics among follicular lymphoma without BCL2 gene translocation. Mod. Pathol. 2008; 21; 973-978.
52. Gu K, Fu K, Jain S et al. t(14;18)-negative follicular lymphomas are associated with a high frequency of BCL6 rearrangement at the alternative breakpoint region. Mod. Pathol. 2009; 22; 1251-1257.
53. Tagawa H, Karube K, Guo Y et al. Trisomy 3 is a specific genomic aberration of t(14;18) negative follicular lymphoma. Leukemia 2007; 21; 2549-2551.
54. Horsman DE, Okamoto I, Ludkovski O et al. Follicular lymphoma lacking the t(14;18)(q32;q21): identification of two disease subtypes. Br. J. Haematol. 2003; 120; 424-433.
55. Gagyi E, Balogh Z, Bodor C et al. Somatic hypermutation of IGVH genes and aberrant somatic hypermutation in follicular lymphoma without BCL-2 gene rearrangement and expression. Haematologica 2008; 93; 1822-1828.