Interphase FISH detection of BCL2 rearrangement in follicular lymphoma using breakpoint-flanking probes

Genes Chromosomes and Cancer

Volumn 27, Issue 1, 2000, Pages 85-94

  Vaandrager, Jan Willem ^a   Schuuring, Ed ^a   Raap, Ton ^a   Philippo, Katja ^a   Kleiverda, Karin ^a   Kluin, Philip ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN;

ARTICLE; CANCER GRADING; CONTROLLED STUDY; DIFFERENTIAL DIAGNOSIS; FLUORESCENCE IN SITU HYBRIDIZATION; FOLLICULAR LYMPHOMA; GENE MAPPING; GENE REARRANGEMENT; HUMAN; HUMAN TISSUE; INTERPHASE; MOLECULAR CLONING; MOLECULAR PROBE; OBSERVER VARIATION; ONCOGENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SOUTHERN BLOTTING;

3' UNTRANSLATED REGIONS; 5' UNTRANSLATED REGIONS; CHROMOSOME BREAKAGE; CHROMOSOMES, HUMAN, PAIR 14; CHROMOSOMES, HUMAN, PAIR 18; DNA; DNA PROBES; DNA, NEOPLASM; GENE REARRANGEMENT; GENES, BCL-2; GENES, IMMUNOGLOBULIN; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INTERPHASE; LEUKOCYTES; LYMPHOMA, FOLLICULAR; PHYSICAL CHROMOSOME MAPPING; PROTO-ONCOGENE PROTEINS C-BCL-2; TONSIL; TONSILLAR NEOPLASMS; TRANSLOCATION, GENETIC;

EID: 0033991304     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2264(200001)27:1<85::AID-GCC11>3.0.CO;2-9     Document Type: Article

References (37)

1. Akasaka T, Akasaka H, Yonetani N, Ohno H, Yamabe H, Fukuhara S, Okuma M. 1998. Refinement of the BCL2/immunoglobulin heavy chain fusion gene in t(14;18)(q32;q21) by polymerase chain reaction amplification for long targets. Genes Chromosomes Cancer 21:17-29.
2. Aslanidis C, de Jong PJ. 1991. Coincidence cloning of Alu PCR products. Proc Natl Acad Sci USA 88:6765-6769.
3. Aster JC, Kobayashi Y, Shiota M, Mori S, Sklar J. 1992. Detection of the t(14;18) at similar frequencies in hyperplastic lymphoid tissues from American and Japanese patients. Am J Pathol 141:291-299.
4. Bentz M, Cabot G, Moos M, Speicher MR, Ganser A, Lichter P, Dohner H. 1994. Detection of chimeric BCR-ABL genes on hone marrow samples and blood smears in chronic myeloid and acute lymphoblastic leukemia by in situ hybridization. Blood 83:1922-1928.
5. Coignet LJ, Schuuring E, Kibbelaar RE, Raap TK, Kleiverda KK, Bertheas MF, Wiegant J, Beverstock G, Kluin PM. 1996. Detection of 11q13 rearrangements in hematologic neoplasias by double-color fluorescence in situ hybridization. Blood 87:1512-1519.
6. De Boer CJ, Vaandrager JW, van Krieken JH, Holmes Z, Kluin PM, Schuuring E. 1997. Visualization of mono-allelic chromosomal aberrations 3′ and 5′ of the cyclin D1 gene in mantle cell lymphoma using DNA fiber fluorescence in situ hybridization. Oncogene 15:1599-1603.
7. Dewald GW, Schad CR, Christensen ER, Tiede AL, Zinsmeister AR, Spurbeck JL, Thibodeau SN, Jalal SM. 1993. The application of fluorescent in situ hybridization to detect Mbcr/abl fusion in variant Ph chromosomes in CML and ALL. Cancer Genet Cytogenet 71:7-14.
8. Florijn RJ, Bonden LAJ, Vrolijk H, Wiegant J, Vaandrager J-W, Baas F, Den Dunnen JT, Tanke HJ, Van Ommen G-JB, Raap AK. 1995. High-resolution DNA fiber-FISH for genomic DNA mapping and colour bar-coding of large genes. Hum Mol Genet 4:831-836.
9. Gaulard P, d'Agay MF, Peuchmaur M, Brousse N, Gisselbrecht C, Solal Celigny P, Diebold J, Mason DY. 1992. Expression of the bcl-2 gene product in follicular lymphoma. Am J Pathol 140:1089-1095.
10. Harris NL, Jaffe ES, Stein H, Banks PM, Chan JK, Cleary ML, Delsol G, De Wolf Peeters C, Falini B, Gatter KC, et al. 1994. A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group. Blood 84:1361-1392.
11. Kozubek S, Lukasova E, Ryznar L, Kozubek M, Liskova A, Govorun RD, Krasavin EA, Horneck G. 1997. Distribution of ABL and BCR genes in cell nuclei of normal and irradiated lymphocytes. Blood 89:4537-4545.
12. Kramer MH, Hermans J, Parker J, Krol AD, Kluin Nelemans JC, Haak HL, van Groningen K, van Krieken JH, de Jong D, Kluin PM. 1996. Clinical significance of bcl2 and p53 protein expression in diffuse large B-cell lymphoma: a population-based study. J Clin Oncol 14:2131-2138.
13. Kramer MH, Hermans J, Wijburg E, Philippo K, Geelen E, van Krieken JH, de Jong D, Maartense E, Schuuring E, Kluin PM. 1998. Clinical relevance of BCL2, BCL6, and MYC rearrangements in diffuse large B-cell lymphoma. Blood 92:3152-3162.
14. Limpens J, de Jong D, van Krieken JH, Price CG, Young BD, van Ommen GJ, Kluin PM. 1991. Bcl-2/JH rearrangements in benign lymphoid tissues with follicular hyperplasia. Oncogene 6:2271-2276.
15. Lopez Guillermo A, Cabanillas F, McDonnell TI, McLaughlin P, Smith T, Pugh W, Hagemeister F, Rodriguez MA, Romaguera JE, Younes A, Sarris AH, Preti HA, Lee MS. 1999. Correlation of Bcl-2 rearrangement with clinical characteristics and outcome in indolent follicular lymphoma. Blood 93:3081-3087.
16. Martin AR, Weisenburger DD, Chan WC, Ruby EI, Anderson JR, Vose JM, Bierman PJ, Bast MA, Daley DT, Armitage JO. 1995. Prognostic value of cellular proliferation and histologic grade in follicular lymphoma. Blood 85:3671-3678.
17. Mikraki V, Ladanyi M, Chaganti RS. 1991. Structural alterations in the 5′ region of the BCL2 gene in follicular lymphomas with BCL2-MBR or BCL2-MCR rearrangements. Genes Chromosomes Cancer 3:117-121.
18. Neves H, Ramos C, da Silva MG, Parreira A, Parreira L. 1999. The nuclear topography of ABL, BCR, PML, and RARa genes: evidence for gene proximity in specific phases of the cell cycle and stages of hematopoietic differentiation. Blood 93:1197-1207.
19. Nguyen PL, Zukerberg LR, Benedict WF, Harris NL. 1996. Immunohistochemical detection of p53, bcl-2, and retinoblastoma proteins in follicular lymphoma. Am J Clin Pathol 105:538-543.
20. Nomdedieu JF, Baiget M, Gaidano G, Estivill C, Lasa A, Rubiol E, Mateu R, Bordes R, Brunet S, Saglio G, Soler J. 1998. p53 Mutation in a case of blastic transformation of follicular lymphoma with double bcl-2 rearrangement (MBR and VCR). Leuk Lymphoma 29:595-605.
21. Pezzella F, Jones M, Ralfkiaer E, Ersboll J, Gatter KC, Mason DY. 1992. Evaluation of bcl-2 protein expression and 14;18 translocation as prognostic markers in follicular lymphoma. Br J Cancer 65:87-89.
22. Poetsch M, Weber-Matthiesen K, Plendl HJ, Grote W, Schlegelberger B. 1996. Detection of the t(14; 18) chromosomal translocation by interphase cytogenetics with yeast-artificial-chromosome probes in follicular lymphoma and nonneoplastic lymphoproliferation. J Clin Oncol 14:963-969.
23. Reed JC, Tanaka S. 1993. Somatic point mutations in the translocated bcl-2 genes of non-Hodgkin's lymphomas and lymphocytic leukemias: implications for mechanisms of tumor progression. Leuk Lymphoma 10:157-163.
24. Rimokh R, Gadoux M, Bertheas MF, Berger F, Garoscio M, Deleage G, Germain D, Magaud JP. 1993. FVT-1, a novel human transcription unit affected by variant translocation t(2;18)(p11;q21) of follicular lymphoma. Blood 81:136-142.
25. Seite P, Hillion J, d'Agay MF, Berger R, Larsen CJ. 1993. BCL2 complex rearrangement in follicular lymphoma: translocation mbr/JH and deletion in the vcr region of the same BCL2 allele. Oncogene 8:3073-3080.
26. Silverman GA, Green ED, Young RL, Jockel JI, Domer PH, Korsmeyer SJ. 1990. Meiotic recombination between yeast artificial chromosomes yields a single clone containing the entire BCL2 protooncogene. Proc Natl Acad Sci USA 87:9913-9917.
27. Silverman GA, Jockel JI, Domer PH, Mohr RM, Taillon Miller P, Korsmeyer SJ. 1991. Yeast artificial chromosome cloning of a two-megabase-size contig within chromosomal band 18q21 establishes physical linkage between BCL2 and plasminogen activator inhibitor type-2. Genomics 9:219-228.
28. Silverman GA. 1993. Isolating vector-insert junctions from yeast artificial chromosomes. PCR Methods Appl 3:141-150.
29. Sinclair PB, Green AR, Grace C, Nacheva EP. 1997. Improved sensitivity of BCR-ABL detection: a triple-probe three-color fluorescence in situ hybridization system. Blood 90:1395-1402.
30. Tanaka S, Louie DC, Kant JA, Reed JC. 1992. Frequent incidence of somatic mutations in translocated BCL2 oncogenes of non-Hodgkin's lymphomas. Blood 79:229-237.
31. Taniwaki M, Sliverman GA, Nishida K, Horiike S, Misawa S, Shimazaki C, Miura I, Nagai M, Abe M, Fukuhara S, et al. 1995. Translocations and amplification of the BCL2 gene are detected in interphase nuclei of non-Hodgkin's lymphoma by in situ hybridization with yeast artificial chromosome clones. Blood 86:1481-1486.
32. Tsujimoto Y, Croce CM. 1986. Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma. Proc Natl Acad Sci USA 83:5214-5218.
33. Tsujimoto Y, Bashir MM, Givol I, Cossman J, Jaffe E, Croce CM. 1987. DNA rearrangements in human follicular lymphoma can involve the 5′ or the 3′ region of the bcl-2 gene. Proc Natl Acad Sci USA 84:1329-1331.
34. Vaandrager JW, Schuuring E, Zwikstra E, De Boer CJ, Kleiverda KK, van Kricken JH, Kluin-Nelemans HC, van Ommen GJ, Raap AK, Kluin PM. 1996. Direct visualization of dispersed 11q13 chromosomal translocations in mantle cell lymphoma by multicolor DNA fiber fluorescence in situ hybridization. Blood 88:1177-1182.
35. Vaandrager JW, Schuuring E, Kluin-Nelemans HC, Dyer MJS, Raap AK, Kluin PM. 1998. DNA fiber fluorescence in situ hybridization analysis of immunoglobulin class switching in B-cell neoplasia: aberrant gene rearrangements in follicle center-cell lymphoma. Blood 92:2871-2878.
36. Willis TG, Jadayel DM, Coignet LJ, Abdul Rauf M, Treleaven JG, Catovsky D, Dyer MJ. 1997. Rapid molecular cloning of rearrangements of the IGHJ locus using long-distance inverse polymerase chain reaction. Blood 90:2456-2464.
37. Zelenetz AD, Chu G, Galili N, Bangs CD, Horning SJ, Donlon TA, Cleary ML, Levy R. 1991. Enhanced detection of the t(14;18) translocation in malignant lymphoma using pulsed-field gel electrophoresis. Blood 78:1552-1560.