Enhanced top-down control during pursuit eye tracking in schizophrenia

European Archives of Psychiatry and Clinical Neuroscience

Volumn 263, Issue 3, 2013, Pages 223-231

  Sprenger, Andreas ^a   Trillenberg, Peter ^a   Nagel, Matthias ^a   Sweeney, John A ^b   Lencer, Rebekka ^a,c  

^a UNIVERSITY OF LÜBECK   (Germany)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Anticipation; Eye deceleration; Prediction; Residual eye velocity; Sensorimotor deficit; Smooth pursuit; Target blanking; Working memory

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DECELERATION; EYE TRACKING; HUMAN; PREDICTION; PRIORITY JOURNAL; SCHIZOPHRENIA; SENSORIMOTOR FUNCTION; VELOCITY;

ADOLESCENT; ADULT; ANALYSIS OF VARIANCE; BLINKING; FEMALE; HUMANS; MALE; MIDDLE AGED; MOTION PERCEPTION; OCULAR MOTILITY DISORDERS; PSYCHOMOTOR PERFORMANCE; PURSUIT, SMOOTH; REACTION TIME; SCHIZOPHRENIA; YOUNG ADULT;

EID: 84879462955     PISSN: 09401334     EISSN: 14338491     Source Type: Journal    
DOI: 10.1007/s00406-012-0332-9     Document Type: Article

References (40)

1. American Psychiatric Association (1994) Diagnostic and statistical manual of mental disorders DSM-IV. American Psychiatric Press, Washington DC
2. Arolt V, Lencer R, Nolte A, Pinnow M, Schwinger E (1996) Eye tracking dysfunction in families with multiple cases of schizophrenia. Eur Arch Psychiatry Clin Neurosci 246:175-181 (Pubitemid 26225919)
3. Barnes GR, Asselman PT (1991) The mechanism of prediction in human smooth pursuit eye movements. J Physiol 439:439-461
4. Barnes GR, Collins CJ (2008) Evidence for a link between the extra-retinal component of random-onset pursuit and the anticipatory pursuit of predictable object motion. J Neurophysiol 100:1135-1146
5. Becker W, Fuchs AF (1985) Prediction in the oculomotor system: smooth pursuit during transient disappearance of a visual target. Exp Brain Res 57:562-575 (Pubitemid 15173688)
6. Bennett SJ, Barnes GR (2003) Human ocular pursuit during the transient disappearance of a visual target. J Neurophysiol 90:2504-2520 (Pubitemid 37266519)
7. Bennett SJ, Barnes GR (2006) Combined smooth and saccadic ocular pursuit during the transient occlusion of a moving visual object. Exp Brain Res 168:313-321 (Pubitemid 41830941)
8. Burke MR, Barnes GR (2007) Sequence learning in two-dimensional smooth pursuit eye movements in humans. J Vis 7:5 (Pubitemid 46164273)
9. Butler PD, Silverstein SM, Dakin SC (2008) Visual perception and its impairment in schizophrenia. Biol Psychiatry 64:40-47 (Pubitemid 351783245)
10. Chen Y, Nakayama K, Levy D, Matthysse S, Holzman P (2003) Processing of global, but not local, motion direction is deficient in schizophrenia. Schizophr Res 61:215-227 (Pubitemid 36513934)
11. Clementz BA, McDowell JE (1994) Smooth pursuit in schizophrenia: abnormalities of open- and closed-loop responses. Psychophysiology 31:79-86 (Pubitemid 24031095)
12. First MB, Gibbon MSRL, Williams JBW, Benjamin LS (1997) Structured clinical interview for DSM-IV axis II personality disorders (SCID-II). American Psychiatric Press, Washington DC
13. Fukushima K, Yamanobe T, Shinmei Y, Fukushima J (2002) Predictive responses of periarcuate pursuit neurons to visual target motion. Exp Brain Res 145:104-120 (Pubitemid 34651740)
14. Haraldsson HM, Ettinger U, Magnusdottir BB, Sigmundsson T, Sigurdsson E, Petursson H (2008) Eye movement deficits in schizophrenia: investigation of a genetically homogenous Icelandic sample. Eur Arch Psychiatry Clin Neurosci 258:373-383
15. Hong LE, Turano KA, O'Neill H, Hao L, Wonodi I, McMahon RP et al (2008) Refining the predictive pursuit endophenotype in schizophrenia. Biol Psychiatry 63:458-464 (Pubitemid 351227355)
16. Hong LE, Turano KA, O'Neill HB, Hao L, Wonodi I, McMahon RP et al (2009) Is motion perception deficit in schizophrenia a consequence of eye-tracking abnormality? Biol Psychiatry 65:1079-1085
17. Hutton SB, Crawford TJ, Gibbins H, Cuthbert I, Barnes TR, Kennard C et al (2001) Short and long term effects of antipsychotic medication on smooth pursuit eye tracking in schizophrenia. Psychopharmacology 157:284-291 (Pubitemid 32905570)
18. Ilg UJ (2008) The role of areas MT and MST in coding of visual motion underlying the execution of smooth pursuit. Vision Res 48:2062-2069
19. Kay SR, Fiszbein A, Opler LA (1987) The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull 13:261-276 (Pubitemid 18039085)
20. Lencer R, Sprenger A, Trillenberg P (2011) Mechanisms of prediction in patients with psychosis. Eur Arch Psychiatry Clin Neurosci 261:93
21. Lencer R, Keedy SK, Reilly JL, McDonough BE, Harris MS, Sprenger A et al (2011) Altered transfer of visual motion information to parietal association cortex in untreated first-episode psychosis: implications for pursuit eye tracking. Psychiatry Res 194:30-38
22. Lencer R, Nagel M, Sprenger A, Zapf S, Erdmann C, Heide W et al (2004) Cortical mechanisms of smooth pursuit eye movements with target blanking. An fMRI study. Eur J Neurosci 19:1430-1436 (Pubitemid 38387221)
23. Lencer R, Reilly JL, Harris MS, Sprenger A, Keshavan MS, Sweeney JA (2010) Sensorimotor transformation deficits for smooth pursuit in first-episode affective psychoses and schizophrenia. Biol Psychiatry 67:217-223
24. Lencer R, Sprenger A, Harris MS, Reilly JL, Keshavan MS, Sweeney JA (2008) Effects of second-generation antipsychotic medication on smooth pursuit performance in antipsychotic-naive schizophrenia. Arch Gen Psychiatry 65:1146-1154
25. Levy DL, Holzman PS, Matthysse S, Mendell NR (1993) Eye tracking dysfunction and schizophrenia: a critical perspective. Schizophr Bull 19:461-536 (Pubitemid 23272620)
26. Lindner A, Thier P, Kircher TT, Haarmeier T, Leube DT (2005) Disorders of agency in schizophrenia correlate with an inability to compensate for the sensory consequences of actions. Curr Biol 15:1119-1124 (Pubitemid 40841355)
27. Lisberger SG (2010) Visual guidance of smooth-pursuit eye movements: sensation, action, and what happens in between. Neuron 66:477-491
28. Nagel M, Sprenger A, Nitschke M, Zapf S, Heide W, Binkofski F et al (2007) Different extraretinal neuronal mechanisms of smooth pursuit eye movements in schizophrenia: an fMRI study. Neuroimage 34:300-309 (Pubitemid 44765251)
29. O'Driscoll GA, Callahan BL (2008) Smooth pursuit in schizophrenia: a meta-analytic review of research since 1993. Brain Cogn 68:359-370
30. Robinson DA, Gordon JL, Gordon SE (1986) A model of the smooth pursuit eye movement system. Biol Cybern 55:43-57 (Pubitemid 17073329)
31. Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E et al (1998) The mini-international neuropsychiatric interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry 59(suppl 20):22-33 (Pubitemid 29001829)
32. Sprenger A, Trillenberg P, Pohlmann J, Herold K, Lencer R, Helmchen C (2011) The role of prediction and anticipation on age-related effects on smooth pursuit eye movements. Ann N Y Acad Sci 1233:168-176
33. Sweeney JA, Luna B, Srinivasagam NM, Keshavan MS, Schooler NR, Haas GL et al (1998) Eye tracking abnormalities in schizophrenia: evidence for dysfunction in the frontal eye fields. Biol Psychiatry 44:698-708 (Pubitemid 28496785)
34. Thaker GK (2008) Neurophysiological endophenotypes across bipolar and schizophrenia psychosis. Schizophr Bull 34:760-773 (Pubitemid 351957568)
35. Thaker GK, Ross DE, Buchanan RW, Adami HM, Medoff DR (1999) Smooth pursuit eye movements to extra-retinal motion signals: deficits in patients with schizophrenia. Psychiatry Res 88:209-219 (Pubitemid 30074176)
36. Thaker GK, Ross DE, Cassady SL, Adami HM, LaPorte D, Medoff DR et al (1998) Smooth pursuit eye movements to extraretinal motion signals: deficits in relatives of patients with schizophrenia. Arch Gen Psychiatry 55:830-836 (Pubitemid 28413046)
37. Trillenberg P, Heide W, Junghanns K, Blankenburg M, Arolt V, Kompf D (1998) Target anticipation and impairment of smooth pursuit eye movements in schizophrenia. Exp Brain Res 120:316-324 (Pubitemid 28221438)
38. van den Berg AV (1988) Human smooth pursuit during transient perturbations of predictable and unpredictable target movement. Exp Brain Res 72:95-108
39. van den Berg AV, Collewijn H (1987) Voluntary smooth eye movements with foveally stabilized targets. Exp Brain Res 68:195-204 (Pubitemid 17153693)
40. Wang J, Brown R, Dobkins KR, McDowell JE, Clementz BA (2010) Diminished parietal cortex activity associated with poor motion direction discrimination performance in schizophrenia. Cereb Cortex 20:1749-1755