Investigation of the function of Candida albicans Als3 by heterologous expression in Candida glabrata

Infection and Immunity

Volumn 81, Issue 7, 2013, Pages 2528-2535

  Fu, Yue ^a,b,d   Phan, Quynh T ^a   Luo, Guanpingsheng ^a   Solis, Norma V ^a   Liu, Yaoping ^a   Cormack, Brendan P ^c   Edwards, John E ^a,b   Ibrahim, Ashraf S ^a,b   Filler, Scott G ^a,b  

^a LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANDIDA ALBICANS ALS3 PROTEIN; FUNGAL PROTEIN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 6; INTERLEUKIN 8; INVASIN; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELOPEROXIDASE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANDIDA ALBICANS; CANDIDA GLABRATA; CONTROLLED STUDY; CYTOKINE RELEASE; ENDOCYTOSIS; FUNGAL VIRULENCE; HETEROLOGOUS EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NEUROTROPISM; NONHUMAN; PATHOGENICITY; PHAGOCYTE; PRIORITY JOURNAL;

EID: 84879458881     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00013-13     Document Type: Article

References (39)

1. Grubb SE, Murdoch C, Sudbery PE, Saville SP, Lopez-Ribot JL, Thornhill MH. 2008. Candida albicans-endothelial cell interactions: a key step in the pathogenesis of systemic candidiasis. Infect. Immun. 76:4370-4377
2. Filler SG, Swerdloff JN, Hobbs C, Luckett PM. 1995. Penetration and damage of endothelial cells by Candida albicans. Infect. Immun. 63:976-983
3. Phan QT, Myers CL, Fu Y, Sheppard DC, Yeaman MR, Welch WH, Ibrahim AS, Edwards JE, Filler SG. 2007. Als3 is a Candida albicans invasin that binds to cadherins and induces endocytosis by host cells. PLoS Biol. 5:e64.doi:10.1371/journal.pbio.0050064.
4. Phan QT, Fratti RA, Prasadarao NV, Edwards JE, Jr, Filler SG. 2005. N-cadherin mediates endocytosis of Candida albicans by endothelial cells. J. Biol. Chem. 280:10455-10461
5. Oh SH, Cheng G, Nuessen JA, Jajko R, Yeater KM, Zhao X, Pujol C, Soll DR, Hoyer LL. 2005. Functional specificity of Candida albicans Als3p proteins and clade specificity of ALS3 alleles discriminated by the number of copies of the tandem repeat sequence in the central domain. Microbiology 151:673- 681
6. Seidl K, Solis NV, Bayer AS, Hady WA, Ellison S, Klashman MC, Xiong YQ, Filler SG. 2012. Divergent responses of different endothelial cell types to infection with Candida albicans and Staphylococcus aureus. PLoS One 7:e39633.doi:10.1371/journal.pone.0039633.
7. Sheppard DC, Yeaman MR, Welch WH, Phan QT, Fu Y, Ibrahim AS, Filler SG, Zhang M, Waring AJ, Edwards JE, Jr. 2004. Functional and structural diversity in the Als protein family of Candida albicans. J. Biol. Chem. 279:30840 -30849
8. Green CB, Zhao X, Hoyer LL. 2005. Use of green fluorescent protein and reverse transcription-PCR to monitor Candida albicans agglutinin-like sequence gene expression in a murine model of disseminated candidiasis. Infect. Immun. 73:1852-1855
9. Coleman DA, Oh SH, Zhao X, Zhao H, Hutchins JT, Vernachio JH, Patti JM, Hoyer LL. 2009. Monoclonal antibodies specific for Candida albicans Als3 that immunolabel fungal cells in vitro and in vivo and block adhesion to host surfaces. J. Microbiol. Methods 78:71-78
10. Mochon AB, Jin Y, Kayala MA, Wingard JR, Clancy CJ, Nguyen MH, Felgner P, Baldi P, Liu H. 2010. Serological profiling of a Candida albicans protein microarray reveals permanent host-pathogen interplay and stage-specific responses during candidemia. PLoS Pathog. 6:e1000827.doi:10.1371/journal.ppat.1000827.
11. Spellberg BJ, Ibrahim AS, Avanesian V, Fu Y, Myers C, Phan QT, Filler SG, Yeaman MR, Edwards JE, Jr. 2006. Efficacy of the anti-Candida rAls3p-N or rAls1p-N vaccines against disseminated and mucosal candidiasis. J. Infect. Dis. 194:256 -260
12. Cleary IA, Reinhard SM, Miller CL, Murdoch C, Thornhill MH, Lazzell AL, Monteagudo C, Thomas DP, Saville SP. 2011. The Candida albicans adhesin Als3p is dispensable for virulence in the mouse model of disseminated candidiasis. Microbiology 157:1806 -1815
13. Braun BR, van Het Hoog M, d'Enfert C, Martchenko M, Dungan J, Kuo A, Inglis DO, Uhl MA, Hogues H, Berriman M, Lorenz M, Levitin A, Oberholzer U, Bachewich C, Harcus D, Marcil A, Dignard D, Iouk T, Zito R, Frangeul L, Tekaia F, Rutherford K, Wang E, Munro CA, Bates S, Gow NA, Hoyer LL, Kohler G, Morschhauser J, Newport G, Znaidi S, Raymond M, Turcotte B, Sherlock G, Costanzo M, Ihmels J, Berman J, Sanglard D, Agabian N, Mitchell AP, Johnson AD, Whiteway M, Nantel A. 2005. A human-curated annotation of the Candida albicans genome. PLoS Genet. 1:e1.doi:10.1371/journal.pgen.0010001.
14. Nobile CJ, Andes DR, Nett JE, Smith FJ, Yue F, Phan QT, Edwards JE, Filler SG, Mitchell AP. 2006. Critical role of Bcr1-dependent adhesins in C. albicans biofilm formation in vitro and in vivo. PLoS Pathog. 2:e63.doi:10.1371/journal.ppat.0020063.
15. Davis D, Wilson RB, Mitchell AP. 2000. RIM101-dependent and -independent pathways govern pH responses in Candida albicans. Mol. Cell. Biol. 20:971-978
16. Cormack BP, Falkow S. 1999. Efficient homologous and illegitimate recombination in the opportunistic yeast pathogen Candida glabrata. Genetics 151:979 -987
17. Frieman MB, McCaffery JM, Cormack BP. 2002. Modular domain structure in the Candida glabrata adhesin Epa1p, a beta1,6 glucan-crosslinked cell wall protein. Mol. Microbiol. 46:479-492
18. Jaffe EA, Nachman RL, Becker CG, Minick CR. 1973. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J. Clin. Invest. 52:2745-2756
19. Phan QT, Belanger PH, Filler SG. 2000. Role of hyphal formation in interactions of Candida albicans with endothelial cells. Infect. Immun. 68:3485-3490
20. Liu Y, Mittal R, Solis NV, Prasadarao NV, Filler SG. 2011. Mechanisms of Candida albicans trafficking to the brain. PLoS Pathog. 7:e1002305.doi:10.1371/journal.ppat.1002305.
21. Stins MF, Nemani PV, Wass C, Kim KS. 1999. Escherichia coli binding to and invasion of brain microvascular endothelial cells derived from humans and rats of different ages. Infect. Immun. 67:5522-5525
22. Ariyachet C, Solis NV, Liu Y, Prasadarao NV, Filler SG, McBride AE. 2013. SR-like RNA-binding protein Slr1 affects Candida albicans filamentation and virulence. Infect. Immun. 81:1267-1276
23. Spellberg BJ, Collins M, French SW, Edwards JE, Jr, Fu Y, Ibrahim AS. 2005. A phagocytic cell line markedly improves survival of infected neutropenic mice. J. Leukoc. Biol. 78:338 -344
24. Schultz J, Kaminker K. 1962. Myeloperoxidase of the leucocyte of normal human blood. I. Content and localization. Arch. Biochem. Biophys. 96: 465-467
25. Sugiyama S, Okada Y, Sukhova GK, Virmani R, Heinecke JW, Libby P. 2001. Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes. Am. J. Pathol. 158:879-891
26. Bos A, Wever R, Roos D. 1978. Characterization and quantification of the peroxidase in human monocytes. Biochim. Biophys. Acta 525:37- 44
27. Ejzykowicz DE, Solis NV, Gravelat FN, Chabot J, Li X, Sheppard DC, Filler SG. 2010. Role of Aspergillus fumigatus DvrA in host cell interactions and virulence. Eukaryot. Cell 9:1432-1440
28. Ejzykowicz DE, Cunha MM, Rozental S, Solis NV, Gravelat FN, Sheppard DC, Filler SG. 2009. The Aspergillus fumigatus transcription factor Ace2 governs pigment production, conidiation and virulence. Mol. Microbiol. 72:155-169
29. Prasadarao NV, Srivastava PK, Rudrabhatla RS, Kim KS, Huang SH, Sukumaran SK. 2003. Cloning and expression of the Escherichia coli K1 outer membrane protein A receptor, a gp96 homologue. Infect. Immun. 71:1680 -1688
30. Brieland J, Essig D, Jackson C, Frank D, Loebenberg D, Menzel F, Arnold B, DiDomenico B, Hare R. 2001. Comparison of pathogenesis and host immune responses to Candida glabrata and Candida albicans in systemically infected immunocompetent mice. Infect. Immun. 69:5046-5055
31. Spellberg B, Ibrahim AS, Edwards JE, Jr, Filler SG. 2005. Mice with disseminated candidiasis die of progressive sepsis. J. Infect. Dis. 192:336-343
32. Villar CC, Kashleva H, Mitchell AP, Dongari-Bagtzoglou A. 2005. Invasive phenotype of Candida albicans affects the host proinflammatory response to infection. Infect. Immun. 73:4588-4595
33. Lionakis MS, Lim JK, Lee CC, Murphy PM. 2011. Organ-specific innate immune responses in a mouse model of invasive candidiasis. J. Innate Immun. 3:180 -199
34. Chen CG, Yang YL, Cheng HH, Su CL, Huang SF, Chen CT, Liu YT, Su IJ, Lo HJ. 2006. Non-lethal Candida albicans cph1/cph1 efg1/efg1 transcription factor mutant establishing restricted zone of infection in a mouse model of systemic infection. Int. J. Immunopathol. Pharmacol. 19:561-565
35. Prozialeck WC, Lamar PC, Appelt DM. 2004. Differential expression of E-cadherin, N-cadherin and beta-catenin in proximal and distal segments of the rat nephron. BMC Physiol. 4:10.doi:10.1186/1472-6793-4-10.
36. Piepenhagen PA, Peters LL, Lux SE, Nelson WJ. 1995. Differential expression of Na(+)-K+)-ATPase, ankyrin, fodrin, and E-cadherin along the kidney nephron. Am. J. Physiol. 269:C1417-C1432
37. Sipsas NV, Lewis RE, Tarrand J, Hachem R, Rolston KV, Raad II, Kontoyiannis DP. 2009. Candidemia in patients with hematologic malignancies in the era of new antifungal agents (2001-2007): stable incidence but changing epidemiology of a still frequently lethal infection. Cancer 115:4745- 4752
38. Graybill JR, Bocanegra R, Luther M, Fothergill A, Rinaldi MJ. 1997. Treatment of murine Candida krusei or Candida glabrata infection with L-743,872. Antimicrob. Agents Chemother. 41:1937-1939
39. Jacobsen ID, Brunke S, Seider K, Schwarzmuller T, Firon A, d'Enfert C, Kuchler K, Hube B. 2010. Candida glabrata persistence in mice does not depend on host immunosuppression and is unaffected by fungal amino acid auxotrophy. Infect. Immun. 78:1066 -1077.