Bronchopulmonary dysplasia in a double-hit mouse model induced by intrauterine hypoxia and postnatal hyperoxia: Closer to clinical features?

Annals of Anatomy

Volumn 195, Issue 4, 2013, Pages 351-358

  Gortner, Ludwig ^a   Monz, Dominik ^a   Mildau, Céline ^a   Shen, Jie ^a,b   Kasoha, Mariz ^a   Laschke, Matthias W ^a   Roolfs, Torge ^c   Schmiedl, Andreas ^c   Meier, Carola ^a   Tutdibi, Erol ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

^c HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Bronchopulmonary dysplasia; Hyperoxia; Intrauterine growth restriction; Lung development; Mouse model

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; OXYGEN; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

ANIMAL TISSUE; ARTICLE; BODY HEIGHT; BODY WEIGHT; BRAIN WEIGHT; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE MODEL; DOWN REGULATION; EMBRYO; FETUS HYPOXIA; GENE; HYPEROXIA; INTRAUTERINE GROWTH RETARDATION; LUNG ALVEOLUS; LUNG DYSPLASIA; LUNG WEIGHT; MORPHOMETRICS; MOUSE; NONHUMAN; SFTPB GENE; SFTPC GENE;

ANIMALS; ANIMALS, NEWBORN; BRAIN; BRONCHOPULMONARY DYSPLASIA; CYTOKINES; DOWN-REGULATION; FEMALE; FETAL HYPOXIA; GENE EXPRESSION; GROWTH; HYPEROXIA; LUNG; MICE; MICE, INBRED C57BL; MICROSCOPY, ELECTRON; MICROSCOPY, ELECTRON, SCANNING; PREGNANCY; PULMONARY SURFACTANT-ASSOCIATED PROTEIN B; PULMONARY SURFACTANT-ASSOCIATED PROTEIN C; RNA, MESSENGER;

ANIMALIA; MUS; RODENTIA;

EID: 84879419956     PISSN: 09409602     EISSN: 16180402     Source Type: Journal    
DOI: 10.1016/j.aanat.2013.02.010     Document Type: Article

References (53)

1. Amy R.W., Bowes D., Burri P.H., Haines J., Thurlbeck W.M. Postnatal growth of the mouse lung. J. Anat. 1977, 124(Pt. 1):131-151.
2. Aslam M., Baveja R., Liang O.D., Fernandez-Gonzalez A., Lee C., Mitsialis S.A., Kourembanas S. Bone marrow stromal cells attenuate lung injury in a murine model of neonatal chronic lung disease. Am. J. Respir. Crit. Care Med. 2009, 180(11):1122-1130.
3. Baker C.D., Abman S.H. Umbilical cord stem cell therapy for bronchopulmonary dysplasia: ready for prime time?. Thorax 2013.
4. Baraldi E., Filippone M. Chronic lung disease after premature birth. N. Engl. J. Med. 2007, 357(19):1946-1955.
5. Bassler D., Stoll B.J., Schmidt B., Asztalos E.V., Roberts R.S., Robertson C.M., Sauve R.S., Trial of Indomethacin Prophylaxis in Preterms Investigators Using a count of neonatal morbidities to predict poor outcome in extremely low birth weight infants: added role of neonatal infection. Pediatrics 2009, 123(1):313-318.
6. Bourbon J.R., Boucherat O., Boczkowski J., Crestani B., Delacourt C. Bronchopulmonary dysplasia and emphysema: in search of common therapeutic targets. Trends Mol. Med. 2009, 15(4):169-179.
7. Burri P.H. Fetal and postnatal development of the lung. Annu. Rev. Physiol. 1984, 46:617-628.
8. Chang Y.S., Oh W., Choi S.J., Sung D.K., Kim S.Y., Choi E.Y., Kang S., Jin H.J., Yang Y.S., Park W.S. Human umbilical cord blood-derived mesenchymal stem cells attenuate hyperoxia-induced lung injury in neonatal rats. Cell Transplant. 2009, 18(8):869-886.
9. Coalson J.J. Pathology of bronchopulmonary dysplasia. Semin. Perinatol. 2006, 30(4):179-184.
10. Dezateux C., Lum S., Hoo A.F., Hawdon J., Costeloe K., Stocks J. Low birth weight for gestation and airway function in infancy: exploring the fetal origins hypothesis. Thorax 2004, 59(1):60-66.
11. Doyle L.W., Ehrenkranz R.A., Halliday H.L. Dexamethasone treatment after the first week of life for bronchopulmonary dysplasia in preterm infants: a systematic review. Neonatology 2010, 98(4):289-296.
12. Fehrenbach, H., Ochs, M. 1998. Studying lung ultrastructure. In: Uhlig, T.A.E., Birkhäuser, S. Methods in Pulmonary Research, Basel, pp. 429-454.
13. Field D., Draper E.S., Fenton A., Papiernik E., Zeitlin J., Blondel B., Cuttini M., Maier R.F., Weber T., Carrapato M., Kollee L., Gadzin J., Van Reempts P., MOSAIC Research Group Rates of very preterm birth in Europe and neonatal mortality rates. Arch. Dis. Childhood Fetal Neonatal Ed. 2009, 94(4):F253-F256.
14. Goncharova E.A. mTOR and vascular remodeling in lung diseases: current challenges and therapeutic prospects. FASEB J. Off. Pub. Fed. Am. Soc. Exp. Biol. 2013.
15. Gortner L., Felderhoff-Muser U., Monz D., Bieback K., Kluter H., Jellema R., Kramer B.W., Keller M., Reiss I., Horn P.A., Giebel B. Regenerative therapies in neonatology: clinical perspectives. Klin. Padiatr. 2012, 224(4):233-240.
16. Gortner L., Hilgendorff A., Bahner T., Ebsen M., Reiss I., Rudloff S. Hypoxia-induced intrauterine growth retardation: effects on pulmonary development and surfactant protein transcription. Biol. Neonate 2005, 88(2):129-135.
17. Gortner L., Misselwitz B., Milligan D., Zeitlin J., Kollee L., Boerch K., Agostino R., Van Reempts P., Chabernaud J.L., Breart G., Papiernik E., Jarreau P.H., Carrapato M., Gadzinowski J., Draper E., members of the MOSAIC Research Group Rates of bronchopulmonary dysplasia in very preterm neonates in Europe: results from the MOSAIC cohort. Neonatology 2011, 99(2):112-117.
18. Greenough A. Long-term pulmonary outcome in the preterm infant. Neonatology 2008, 93(4):324-327.
19. Hayes D., Feola D.J., Murphy B.S., Shook L.A., Ballard H.O. Pathogenesis of bronchopulmonary dysplasia. Resp. Int. Rev. Thorac. Dis. 2010, 79(5):425-436.
20. Heymann D. Autophagy: a protective mechanism in response to stress and inflammation. Curr. Opin. Invest. Drugs (London, England: 2000) 2006, 7(5):443-450.
21. Hoo A.F., Stocks J., Lum S., Wade A.M., Castle R.A., Costeloe K.L., Dezateux C. Development of lung function in early life: influence of birth weight in infants of nonsmokers. Am. J. Respir. Crit. Care Med. 2004, 170(5):527-533.
22. Hsia C.C., Hyde D.M., Ochs M., Weibel E.R., ATS/ERS Joint Task Force on Quantitative Assessment of Lung Structure An official research policy statement of the American Thoracic Society/European Respiratory Society: standards for quantitative assessment of lung structure. Am. J. Respir. Crit. Care Med. 2010, 181(4):394-418.
23. Husain A.N., Siddiqui N.H., Stocker J.T. Pathology of arrested acinar development in postsurfactant bronchopulmonary dysplasia. Hum. Pathol. 1998, 29(7):710-717.
24. Ikegami M., Jobe A.H. Surfactant protein metabolism in vivo. Biochim. Biophys. Acta 1998, 1408(2-3):218-225.
25. Jansson T., Aye I.L., Goberdhan D.C. The emerging role of mTORC1 signaling in placental nutrient-sensing. Placenta 2012, 33(Suppl. 2):e23-e29.
26. Joss-Moore L.A., Metcalfe D.B., Albertine K.H., McKnight R.A., Lane R.H. Epigenetics and fetal adaptation to perinatal events: diversity through fidelity. J. Anim. Sci. 2010, 88(13 Suppl.):E216-E222.
27. Knust J., Ochs M., Gundersen H.J., Nyengaard J.R. Stereological estimates of alveolar number and size and capillary length and surface area in mice lungs. Anat. Record (Hoboken, N.J.: 2007) 2009, 292(1):113-122.
28. Kramer B.W., Kallapur S., Newnham J., Jobe A.H. Prenatal inflammation and lung development. Semin. Fetal Neonatal Med. 2009, 14(1):2-7.
29. Leontieva O.V., Natarajan V., Demidenko Z.N., Burdelya L.G., Gudkov A.V., Blagosklonny M.V. Hypoxia suppresses conversion from proliferative arrest to cellular senescence. PNAS 2012, 109(33):13314-13318.
30. Maritz G.S., Morley C.J., Harding R. Early developmental origins of impaired lung structure and function. Early Hum. Dev. 2005, 81(9):763-771.
31. Meier C., Middelanis J., Wasielewski B., Neuhoff S., Roth-Haerer A., Gantert M., Dinse H.R., Dermietzel R., Jensen A. Spastic paresis after perinatal brain damage in rats is reduced by human cord blood mononuclear cells. Pediatr. Res. 2006, 59(2):244-249.
32. Mello R.R., Silva K.S., Rodrigues M.C., Chalfun G., Ferreira R.C., Delamonica J.V. Predictive factors for neuromotor abnormalities at the corrected age of 12months in very low birth weight premature infants. Arq. Neuropsiquiatr. 2009, 67(2A):235-241.
33. Pfaffl M.W., Horgan G.W., Dempfle L. Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res. 2002, 30(9):e36.
34. Ramakers C., Ruijter J.M., Deprez R.H., Moorman A.F. Assumption-free analysis of quantitative real-time polymerase chain reaction (PCR) data. Neurosci. Lett. 2003, 339(1):62-66.
35. Seger, N., Soll, R. 2009. Animal derived surfactant extract for treatment of respiratory distress syndrome. Cochrane database of systematic reviews (Online), vol. 2, no. 2. pp. CD007836.
36. Soothill P.W., Nicolaides K.H., Campbell S. Prenatal asphyxia, hyperlacticaemia, hypoglycaemia, and erythroblastosis in growth retarded fetuses. Br. Med. J. (Clin. Res. Ed.) 1987, 294(6579):1051-1053.
37. Stichtenoth G., Demmert M., Bohnhorst B., Stein A., Ehlers S., Heitmann F., Rieger-Fackeldey E., Olbertz D., Roll C., Emeis M., Mogel M., Schiffmann H., Wieg C., Wintgens J., Herting E., Gopel W., Hartel C. Major contributors to hospital mortality in very-low-birth-weight infants: data of the birth year 2010 cohort of the German Neonatal Network. Klin. Padiatr. 2012, 224(4):276-281.
38. Stimac T., Petrovic O., Krajina R., Finderle A. The influence of pre-eclampsia on fetal lung maturity. Int. J. Gynaecol. Obst. Off. Organ Int. Fed. Gynaecol. Obst. 2012, 118(1):18-20.
39. Tan C.Y., Hagen T. Post-translational regulation of mTOR complex 1 in hypoxia and reoxygenation. Cell. Signal. 2013.
40. Thomas W., Speer C.P. Nonventilatory strategies for prevention and treatment of bronchopulmonary dysplasia-what is the evidence?. Neonatology 2008, 94(3):150-159.
41. Tschanz S.A., Burri P.H., Weibel E.R. A simple tool for stereological assessment of digital images: the STEPanizer. J. Microsc. 2011, 243(1):47-59.
42. Tutdibi E., Hunecke A., Lindner U., Monz D., Gortner L. Levels of cytokines in umbilical cord blood in relation to spontaneous term labor. J. Perinat. Med. 2012, 40(5):527-532.
43. van Haaften T., Byrne R., Bonnet S., Rochefort G.Y., Akabutu J., Bouchentouf M., Rey-Parra G.J., Galipeau J., Haromy A., Eaton F., Chen M., Hashimoto K., Abley D., Korbutt G., Archer S.L., Thebaud B. Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats. Am. J. Respir. Crit. Care Med. 2009, 180(11):1131-1142.
44. Van Marter L.J., Kuban K.C., Allred E., Bose C., Dammann O., O'Shea M., Laughon M., Ehrenkranz R.A., Schreiber M.D., Karna P., Leviton A. Does bronchopulmonary dysplasia contribute to the occurrence of cerebral palsy among infants born before 28 weeks of gestation?. Arch. Dis. Childhood Fetal Neonatal Ed. 2011, 96(1):F20-F29. ELGAN Study Investigators.
45. Vasilescu D.M., Knudsen L., Ochs M., Weibel E.R., Hoffman E.A. Optimized murine lung preparation for detailed structural evaluation via micro-computed tomography. J. Appl. Physiol. (Bethesda, MD: 1985) 2012, 112(1):159-166.
46. Vosdoganes P., Lim R., Moss T.J., Wallace E.M. Cell therapy: a novel treatment approach for bronchopulmonary dysplasia. Pediatrics 2012, 130(4):727-737.
47. Vrijlandt E.J., Gerritsen J., Boezen H.M., Grevink R.G., Duiverman E.J. Lung function and exercise capacity in young adults born prematurely. Am. J. Respir. Crit. Care Med. 2006, 173(8):890-896.
48. Warner B.B., Stuart L.A., Papes R.A., Wispe J.R. Functional and pathological effects of prolonged hyperoxia in neonatal mice. Am. J. Physiol. 1998, 275(1 Pt 1):L110-L117.
49. Weber J.D., Gutmann D.H. Deconvoluting mTOR biology. Cell Cycle (Georgetown, TX) 2012, 11(2):236-248.
50. Weibel E.R. Stereological Methods: Practical Methods for Biological Morphometry 1979, Academic Press, New York.
51. Wood N.S., Costeloe K., Gibson A.T., Hennessy E.M., Marlow N., Wilkinson A.R., EPICure Study Group The EPICure study: associations and antecedents of neurological and developmental disability at 30 months of age following extremely preterm birth. Arch. Dis. Childhood Fetal Neonatal Ed. 2005, 90(2):F134-F140.
52. Zhang X., Wang H., Shi Y., Peng W., Zhang S., Zhang W., Xu J., Mei Y., Feng Z. Role of bone marrow-derived mesenchymal stem cells in the prevention of hyperoxia-induced lung injury in newborn mice. Cell Biol. Int. 2012, 36(6):589-594.
53. Zoetis T., Hurtt M.E. Species comparison of lung development. Birth Defects Res. B, Develop. Reprod. Toxicol. 2003, 68(2):121-124.