Benzofused hydroxamic acids: Useful fragments for the preparation of histone deacetylase inhibitors. Part 1: Hit identification

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 14, 2013, Pages 4091-4095

  Marastoni, Elena ^a   Bartoli, Sandra ^a   Berettoni, Marco ^a   Cipollone, Amalia ^a   Ettorre, Alessandro ^a   Fincham, Christopher I ^a   Mauro, Sandro ^a   Paris, Marielle ^a   Porcelloni, Marina ^a   Bigioni, Mario ^a   Binaschi, Monica ^a   Nardelli, Federica ^a   Parlani, Massimo ^a   Maggi, Carlo A ^a   Fattori, Daniela ^a  

^a Menarini Ricerche SpA   (Italy)

Author keywords

Fragment approach; HDAC; Hydroxamic acids

Indexed keywords

HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID;

ARTICLE; BINDING AFFINITY; DRUG CYTOTOXICITY; MOLECULAR WEIGHT;

CELL SURVIVAL; HCT116 CELLS; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HUMANS; HYDROXAMIC ACIDS; PROTEIN BINDING; THIOPHENES;

EID: 84879415316     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.05.053     Document Type: Article

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