Family-based study of AVPR1B association and interaction with stressful life events on depression and anxiety in suicide attempts

Neuropsychopharmacology

Volumn 38, Issue 8, 2013, Pages 1504-1511

  Ben Efraim, Yair J ^a   Wasserman, Danuta ^a   Wasserman, Jerzy ^a   Sokolowski, Marcus ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

arginine vasopressin; CRHR1; depression; G E; HPA axis; stress; suicidality

Indexed keywords

LIGAND; VASOPRESSIN V1B RECEPTOR;

ADULT; ANXIETY DISORDER; ARTICLE; DEPRESSION; EXON; FAMILY STUDY; FEMALE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE ENVIRONMENT INTERACTION; HAPLOTYPE; HUMAN; LIFE STRESS; LIGAND BINDING; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGENY; SINGLE NUCLEOTIDE POLYMORPHISM; SUICIDE ATTEMPT;

ADOLESCENT; ADULT; ANXIETY; DEPRESSION; FAMILY; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC VARIATION; HUMANS; LIFE CHANGE EVENTS; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, VASOPRESSIN; RETROSPECTIVE STUDIES; SUICIDE, ATTEMPTED; YOUNG ADULT;

EID: 84879414318     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2013.49     Document Type: Article

References (49)

1. Asimit J, Zeggini E (2010). Rare variant association analysis methods for complex traits. Annu Rev Genet 44: 293-308.
2. Balanovsky O, Rootsi S, Pshenichnov A, Kivisild T, Churnosov M, Evseeva I et al (2008). Two sources of the Russian patrilineal heritage in their Eurasian context. Am J Human Genet 82: 236-250. (Pubitemid 351735953)
3. Bao AM, Swaab DF (2010). Corticotropin-releasing hormone and arginine vasopressin in depression focus on the human postmortem hypothalamus. Vitam Horm 82: 339-365.
4. Bardeleben U, Holsboer F (1989). Cortisol response to a combined dexamethasone-human corticotrophin-releasing hormone challenge in patients with depression. J Neuroendocrinol 1: 485-488. (Pubitemid 20074394)
5. Barrett JC, Fry B, Maller J, Daly MJ (2005). Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21: 263-265. (Pubitemid 40202029)
6. Beck AT, Beck R, Kovacs M (1975). Classification of suicidal behaviors: I. Quantifying intent and medical lethality. Am J Psychiatry 132: 285-287.
7. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J (1961). An inventory for measuring depression. Arch Gen Psychiatry 4: 561-571.
8. Ben-Efraim YJ, Wasserman D, Wasserman J, Sokolowski M (2011). Gene-environment interactions between CRHR1 variants and physical assault in suicide attempts. Genes Brain Behav 10: 663-672.
9. Ben-Efraim YJ, Wasserman D, Wasserman J, Sokolowski M (2012). Family-based study of HTR2A in suicide attempts: observed gene, gene x environment and parent-of-origin associations. Mol Psychiatry (doi:10.1038/mp.2012.86).
10. Binder EB, Nemeroff CB (2010). The CRF system, stress, depression and anxiety-insights from human genetic studies. Mol Psychiatry 15: 574-588.
11. Binder EB, Owens MJ, Liu W, Deveau TC, Rush AJ, Trivedi MH et al (2010). Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response. Arch Gen Psychiatry 67: 369-379.
12. Brezo J, Klempan T, Turecki G (2008). The genetics of suicide: a critical review of molecular studies. Psychiatr Clin North Am 31: 179-203. (Pubitemid 351551424)
13. Browning BL, Browning SR (2009). A unified approach to genotype imputation and haplotype-phase inference for large data sets of trios and unrelated individuals. Am J Human Genet 84: 210-223.
14. Cagliani R, Fumagalli M, Pozzoli U, Riva S, Cereda M, Comi GP et al (2009). A complex selection signature at the human AVPR1B gene. BMC Evol Biol 9: 123.
15. Cordell HJ, Barratt BJ, Clayton DG (2004). Case/pseudocontrol analysis in genetic association studies: a unified framework for detection of genotype and haplotype associations, gene-gene and gene-environment interactions, and parent-of-origin effects. Genet Epidemiol 26: 167-185. (Pubitemid 38420332)
16. Cordell HJ, Clayton DG (2002). A unified stepwise regression procedure for evaluating the relative effects of polymorphisms within a gene using case/control or family data: application to HLA in type 1 diabetes. Am J Human Genet 70: 124-141. (Pubitemid 34031703)
17. Dempster EL, Burcescu I, Wigg K, Kiss E, Baji I, Gadoros J et al (2007). Evidence of an association between the vasopressin V1b receptor gene (AVPR1B) and childhood-onset mood disorders. Arch Gen Psychiatry 64: 1189-1195. (Pubitemid 47529343)
18. Griebel G, Stemmelin J, Gal CS, Soubrie P (2005). Non-peptide vasopressin V1b receptor antagonists as potential drugs for the treatment of stress-related disorders. Curr Pharm Des 11: 1549-1559. (Pubitemid 40691451)
19. Hoffmann TJ, Lange C, Vansteelandt S, Laird NM (2009). Gene-environment interaction tests for dichotomous traits in trios and sibships. Genet Epidemiol 33: 691-699.
20. Horvath S, Xu X, Lake SL, Silverman EK, Weiss ST, Laird NM (2004). Family-based tests for associating haplotypes with general phenotype data: application to asthma genetics. Genet Epidemiol 26: 61-69. (Pubitemid 38036644)
21. Kayser M, Lao O, Anslinger K, Augustin C, Bargel G, Edelmann J et al (2005). Significant genetic differentiation between Poland and Germany follows present-day political borders, as revealed by Y-chromosome analysis. Hum Genet 117: 428-443. (Pubitemid 41236364)
22. Keck ME, Kern N, Erhardt A, Unschuld PG, Ising M, Salyakina D et al (2008). Combined effects of exonic polymorphisms in CRHR1 and AVPR1B genes in a case/control study for panic disorder. Am J Med Genet B Neuropsychiatr Genet 147B: 1196-1204.
23. Leszczynska-Rodziewicz A, Szczepankiewicz A, Dmitrzak-Weglarz M, Skibinska M, Hauser J (2012). Association between functional polymorphism of the AVPR1b gene and polymorphism rs1293651 of the CRHR1 gene and bipolar disorder with psychotic features. J Affect Disord 138: 490-493.
24. Lönnqvist J (2009). Major psychiatric disorders in suicide and suicide attempters. In: Wasserman DWasserman C (eds) Oxford Textbook of Suicidology and Suicide Prevention: A Global Perspective. Oxford University Press Inc: New York, NY, USA, pp 275-286.
25. Mann JJ, Arango VA, Avenevoli S, Brent DA, Champagne FA, Clayton P et al (2009). Candidate endophenotypes for genetic studies of suicidal behavior. Biol Psychiatry 65: 556-563.
26. Mann JJ, Currier D, Stanley B, Oquendo MA, Amsel LV, Ellis SP (2006). Can biological tests assist prediction of suicide in mood disorders? Int J Neuropsychopharmacol 9: 465-474.
27. Merali Z, Kent P, Du L, Hrdina P, Palkovits M, Faludi G et al (2006). Corticotropin-releasing hormone, arginine vasopressin, gastrin-releasing peptide, and neuromedin B alterations in stress-relevant brain regions of suicides and control subjects. Biol Psychiatry 59: 594-602. (Pubitemid 43357953)
28. Mlynarik M, Zelena D, Bagdy G, Makara GB, Jezova D (2007). Signs of attenuated depression-like behavior in vasopressin deficient Brattleboro rats. Horm Behav 51: 395-405. (Pubitemid 46365691)
29. Murat B, Devost D, Andres M, Mion J, Boulay V, Corbani M et al (2012). V1b and CRHR1 receptor heterodimerization mediates synergistic biological actions of vasopressin and CRH. Mol Endocrinol 26: 502-520.
30. Nyholt DR (2004). A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am J Hum Genet 74: 765-769. (Pubitemid 38420107)
31. Purba JS, Hoogendijk WJ, Hofman MA, Swaab DF (1996). Increased number of vasopressin- and oxytocin-expressing neurons in the paraventricular nucleus of the hypothalamus in depression. Arch Gen Psychiatry 53: 137-143. (Pubitemid 26050037)
32. Rene P, de Keyzer Y (2002). The vasopressin receptor of corticotroph pituitary cells. Prog Brain Res 139: 345-357. (Pubitemid 35460901)
33. Rene P, Lenne F, Ventura MA, Bertagna X, de Keyzer Y (2000). Nucleotide sequence and structural organization of the human vasopressin pituitary receptor (V3) gene. Gene 241: 57-64.
34. Roper J, O'Carroll AM, Young W 3rd, Lolait S (2011). The vasopressin Avpr1b receptor: molecular and pharmacological studies. Stress 14: 98-115.
35. Rosser ZH, Zerjal T, Hurles ME, Adojaan M, Alavantic D, Amorim A et al (2000). Y-chromosomal diversity in Europe is clinal and influenced primarily by geography, rather than by language. Am J Hum Genet 67: 1526-1543.
36. Schwender H, Taub MA, Beaty TH, Marazita ML, Ruczinski I (2012). Rapid testing of SNPs and gene-environment interactions in case-parent trio data based on exact analytic parameter estimation. Biometrics 68: 766-773.
37. Scott LV, Dinan TG (1998). Vasopressin and the regulation of hypothalamic-pituitary-adrenal axis function: implications for the pathophysiology of depression. Life Sci 62: 1985-1998. (Pubitemid 28239711)
38. Sokolowski M, Ben-Efraim YJ, Wasserman J, Wasserman D (2012). Glutamatergic GRIN2B and polyaminergic ODC1 genes in suicide attempts: associations and gene-environment interactions with childhood/adolescent physical assault. Mol Psychiatry (doi:10.1038/mp.2012.112).
39. Strimmer K (2008). fdrtool: a versatile R package for estimating local and tail area-based false discovery rates. Bioinformatics 24: 1461-1462. (Pubitemid 351851002)
40. Sugimoto T, Saito M, Mochizuki S, Watanabe Y, Hashimoto S, Kawashima H (1994). Molecular cloning and functional expression of a cDNA encoding the human V1b vasopressin receptor. J Biol Chem 269: 27088-27092.
41. The 1000 Genomes Project Consortium (2010). A map of human genome variation from population-scale sequencing. Nature 467: 1061-1073.
42. van West D, Del-Favero J, Aulchenko Y, Oswald P, Souery D, Forsgren T et al (2004). A major SNP haplotype of the arginine vasopressin 1B receptor protects against recurrent major depression. Mol Psychiatry 9: 287-292. (Pubitemid 38496720)
43. van West D, Del-Favero J, Deboutte D, Van Broeckhoven C, Claes S (2009). Arginine vasopressin receptor gene-based single-nucleo-tide polymorphism analysis in attention deficit hyperactivity disorder. Psychiatr Genet 19: 102-103.
44. van West D, Del-Favero J, Deboutte D, Van Broeckhoven C, Claes S (2010). Associations between common arginine vasopressin 1b receptor and glucocorticoid receptor gene variants and HPA axis responses to psychosocial stress in a child psychiatric population. Psychiatry Res 179: 64-68.
45. Wasserman D, Geijer T, Rozanov V, Wasserman J (2005). Suicide attempt and basic mechanisms in neural conduction: Relationships to the SCN8A and VAMP4 genes. Am J Med Genet B: Neuropsychiatr Genet 133B: 116-119. (Pubitemid 40175628)
46. Wasserman D, Geijer T, Sokolowski M, Rozanov V, Wasserman J (2007). Nature and nurture in suicidal behavior, the role of genetics: some novel findings concerning personality traits and neural conduction. Physiol Behav 92: 245-249. (Pubitemid 47374255)
47. Wasserman D, Sokolowski M, Rozanov V, Wasserman J (2008). The CRHR1 gene: a marker for suicidality in depressed males exposed to low stress. Genes Brain Behav 7: 14-19.
48. World Health Organization (1997). Composite International Diagnostic Interview (CIDI, version 2.1). WHO: Geneva, Switzerland.
49. Young SF, Griffante C, Aguilera G (2007). Dimerization between vasopressin V1b and corticotropin releasing hormone type 1 receptors. Cell Mol Neurobiol 27: 439-461. (Pubitemid 46763890)