Current achievements with topical negative pressure to improve wound healing in dehiscent ischemic stumps of diabetic patients: A case series

International Journal of Lower Extremity Wounds

Volumn 12, Issue 2, 2013, Pages 138-145

  Georgakarakos, Efstratios ^a   Charalampidis, Dimitris ^a   Kakagia, Despoina ^a   Georgiadis, George S ^a   Lazarides, Miltos K ^a   Papanas, Nikolaos ^b  

^a DEMOCRITUS UNIVERSITY OF THRACE   (Greece)

^b DEMOCRITUS UNIVERSITY OF THRACE   (Greece)

Author keywords

diabetes; granulation; ischemia; negative pressure treatment; wound healing

Indexed keywords

ADULT; AGED; AMPUTATION STUMP; ARTICLE; BACTERIUM ISOLATION; CASE REPORT; CONTINUOUS AMBULATORY PERITONEAL DIALYSIS; DEBRIDEMENT; DIABETIC OBESITY; DIABETIC PATIENT; FOLLOW UP; FOOT AMPUTATION; HEART FAILURE; HOSPITAL ADMISSION; HUMAN; IMMOBILIZATION; LEG REVASCULARIZATION; LIMB ISCHEMIA; LIMB SALVAGE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; POPLITEAL ARTERY ANEURYSM; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; TOE GANGRENE; VACUUM ASSISTED CLOSURE; WOUND CLOSURE; WOUND DEHISCENCE; WOUND HEALING;

DIABETES; GRANULATION; ISCHEMIA; NEGATIVE PRESSURE TREATMENT; WOUND HEALING;

AGED; AMPUTATION STUMPS; DIABETES MELLITUS, TYPE 2; DIABETIC FOOT; HUMANS; MALE; MIDDLE AGED; NEGATIVE-PRESSURE WOUND THERAPY; SURGICAL WOUND DEHISCENCE; WOUND HEALING;

EID: 84879404618     PISSN: 15347346     EISSN: 15526941     Source Type: Journal    
DOI: 10.1177/1534734613483769     Document Type: Article

References (42)

1. Morykwas MJ, Simpson J, Punger K, Argenta A, Kremers L, Argenta J. Vacuum-assisted closure: state of basic research and physiologic foundation. Plast Reconstr Surg. 2006 ; 117: 121S - 126S
2. Mouës CM, Heule F, Hovius SE. A review of topical negative pressure therapy in wound healing: sufficient evidence?. Am J Surg. 2011 ; 201: 544-556
3. Schintler MV. Negative pressure therapy: theory and practice. Diabetes Metab Res Rev. 2012 ; 28: 72-77
4. Morykwas MJ, Argenta LC, Shelton-Brown EI, McGuirt W. Vacuum-assisted closure: a new method for wound control and treatment: animal studies and basic foundation. Ann Plast Surg. 1997 ; 38: 553-562
5. Timmers MS, Le Cessie S, Banwell P, Jukema GN. The effects of varying degrees of pressure delivered by negative-pressure wound therapy on skin perfusion. Ann Plast Surg. 2005 ; 55: 665-671
6. Kamolz LP, Andel H, Haslik W, Winter W, Meissl G, Frey M. Use of subatmospheric pressure therapy to prevent burn wound progression in human: first experiences. Burns. 2004 ; 30: 253-258
7. Simman R, Forte R, Silverberg B, Moriera-Gonzalez A, Williams F. A comparative histological pilot study of skin graft take with tie-over bolster dressing versus vacuum assisted closure in a pig model. Wounds. 2004 ; 16: 76-80
8. Stechmiller JK, Kilpadi DV, Childress B, Schultz GS. Effect of vacuum assisted closure therapy on the expression of cytokines and proteases in wound fluid of adults with pressure ulcers. Wound Repair Regen. 2006 ; 14: 371-374
9. Moues CM, van Toorenenbergen AW, Heule F, Hop WC, Hovius SE. The role of topical negative pressure in wound repair: expression of biochemical markers in wound fluid during wound healing. Wound Repair Regen. 2008 ; 16: 488-494
10. Ngo QD, Vickery K, Deva AK. The effect of topical negative pressure on wound biofilms using an in vitro wound model. Wound Repair Regen. 2012 ; 20: 83-90
11. Scherer SS, Pietramaggiori G, Mathews JC, Prsa MJ, Huang S, Orgill DP. The mechanism of action of the vacuum assisted closure device. Plast Reconstr Surg. 2008 ; 122: 786-797
12. Chen SZ, Li J, Li XY, Xu LS. Effects of vacuum-assisted closure on wound microcirculation: an experimental study. Asian J Surg. 2005 ; 28: 211-217
13. Labler L, Rancan M, Mica L, Härter L, Mihic-Probst D, Keel M. Vacuum-assisted closure therapy increases local interleukin 8 and vascular endothelial growth factor levels in traumatic wounds. J Trauma. 2009 ; 66: 749-757
14. Greene AK, Puder M, Roy R, et al. Microdeformational wound therapy: effects on angiogenesis and matrix metalloproteinases in chronic wounds of 3 debilitated patients. Ann Plast Surg. 2006 ; 56: 418-422
15. Fabian TS, Kaufman HJ, Lett DE, et al. The evaluation of subatmospheric pressure and hyperbaric oxygen in ischemic full-thickness wound healing. Am Surg. 2000 ; 66: 1136-1143
16. Kakagia D, Karadimas E, Drosos G, et al. Vacuum-assisted closure downgrades reconstructive demands in high-risk patients with severe lower extremity injuries. Acta Chir Plast. 2009 ; 5: 59-64
17. Armstrong DG, Lavery LA. Negative pressure wound therapy after partial diabetic foot amputation: a multicenter, randomized controlled trial. Lancet. 2005 ; 366: 1704-1710
18. Kasai Y, Nemoto H, Kimura N, Ito Y, Sumiya N. Application of low-pressure negative pressure wound therapy to ischaemic wounds. J Plast Reconstr Aesthet Surg. 2012 ; 65: 395-398
19. Papanas N, Lazarides MK. Diabetic foot amputations in Greece: where do we go from here. Int J Low Extrem Wounds. 2011 ; 10: 4-5
20. Skoutas D, Papanas N, Georgiadis GS, et al. Risk factors for ipsilateral reamputation in patients with diabetic foot lesions. Int J Low Extrem Wounds. 2009 ; 8: 69-74
21. Papanas N, Eleftheriadou I, Tentolouris N, Maltezos E. Advances in the topical treatment of diabetic foot ulcers. Curr Diabetes Rev. 2012 ; 8: 209-218
22. Papanas N, Maltezos E. Growth factors in the treatment of diabetic foot ulcers: new technologies, any promises?. Int J Low Extrem Wounds. 2007 ; 6: 37-53
23. Tiaka EK, Papanas N, Manolakis AC, Georgiadis GS. Epidermal growth factor in the treatment of diabetic foot ulcers: an update. Perspect Vasc Surg Endovasc Ther. 2012 ; 24: 37-44
24. Tiaka EK, Papanas N, Manolakis AC, Maltezos E. The role of hyperbaric oxygen in the treatment of diabetic foot ulcers. Angiology. 2012 ; 63: 302-314
25. Gregor S, Maegele M, Sauerland S, Krahn JF, Peinemann F, Lange S. Negative pressure wound therapy: a vacuum of evidence?. Arch Surg. 2008 ; 143: 189-196
26. Schintler MV. Negative pressure therapy: theory and practice. Diabetes Metab Res Rev. 2012 ; 28: 72-77
27. Wu SC, Marston W, Armstrong DG. Wound care: the role of advanced wound healing technologies. J Vasc Surg. 2010 ; 52: 59S - 66S
28. Xie X, McGregor M, Dendukuri N. The clinical effectiveness of negative pressure wound therapy: a systematic review. J Wound Care. 2010 ; 19: 490-495
29. Eneroth M, van Houtum WH. The value of debridement and vacuum-assisted closure (V.A.C.) therapy in diabetic foot ulcers. Diabetes Metab Res Rev. 2008 ; 24: S76 - S80
30. Aust MC, Spies M, Guggenheim M, et al. Lower limb revascularization preceding surgical wound coverage - an interdisciplinary algorithm for chronic wound closure. J Plast Reconstr Aesthet Surg. 2008 ; 6: 925-933
31. Georgakarakos E, Papanas N, Papadaki E, Georgiadis GS, Maltezos E, Lazarides MK. Endovascular treatment of critical ischemia in the diabetic foot: new thresholds, new anatomies. Angiology. 2012 ;:
32. Armstrong DG, Lavery LA, Boulton AJ. Negative pressure wound therapy via vacuum-assisted closure following partial foot amputation: what is the role of wound chronicity?. Int Wound J. 2007 ; 4: 79-86
33. Blume PA, Walters J, Payne W, Ayala J, Lantis J. Comparison of negative pressure wound therapy using vacuum-assisted closure with advanced moist wound therapy in the treatment of diabetic foot ulcers: a multicenter randomized controlled trial. Diabetes Care. 2008 ; 31: 631-636
34. Stone PA, Back MR, Armstrong PA, et al. Midfoot amputations expand limb salvage rates for diabetic foot infections. Ann Vasc Surg. 2005 ; 19: 805-811
35. Mayer D, Hasse B, Koelliker J, et al. Long-term results of vascular graft and artery preserving treatment with negative pressure wound therapy in Szilagyi grade III infections justify a paradigm shift. Ann Surg. 2011 ; 254: 754-759
36. Gibbons GW, Shaw PM. Diabetic vascular disease: characteristics of vascular disease unique to the diabetic patient. Semin Vasc Surg. 2012 ; 25: 89-92
37. Graziani L, Silvestro A, Bertone V, et al. Vascular involvement in diabetic subjects with ischemic foot ulcer: a new morphologic categorization of disease severity. Eur J Vasc Endovasc Surg. 2007 ; 33: 453-460
38. Ruangsetakit C, Chinsakchai K, Mahawongkajit P, Wongwanit C, Mutirangura P. Transcutaneous oxygen tension: a useful predictor of ulcer healing in critical limb ischaemia. J Wound Care. 2010 ; 19: 202-206
39. Arsenault KA, Al-Otaibi A, Devereaux PJ, Thorlund K, Tittley JG, Whitlock RP. The use of transcutaneous oximetry to predict healing complications of lower limb amputations: a systematic review and meta-analysis. Eur J Vasc Endovasc Surg. 2012 ; 43: 329-336
40. Lepäntalo M, Apelqvist J, Setacci C, et al. Chapter V: Diabetic foot. Eur J Vasc Endovasc Surg. 2011 ; 42: S60 - S74
41. Papanas N, Maltezos E. The diabetic foot: established and emerging treatments. Acta Clin Belg. 2007 ; 62: 230-238
42. Antonoglou C, Papanas N, Maltezos E. Lipid-lowering therapy in the diabetic foot: seeing the whole iceberg and not just the tip. Curr Vasc Pharmacol. 2012 ;: