Selective inhibition of PCAF suppresses microglial-mediated β-amyloid neurotoxicity

International Journal of Molecular Medicine

Volumn 32, Issue 2, 2013, Pages 469-475

  Park, Soo Yeon ^a   Lee, Yoo Hyun ^b   Seong, Ah Reum ^a   Lee, Jeongmin ^c   Jun, Woojin ^d   Yoon, Ho Geun ^a  

^a Yonsei University College of Medicine   (South Korea)

^b Suwon University   (South Korea)

^c Kyung Hee University   (South Korea)

^d Chonnam National University   (South Korea)

Author keywords

amyloid; Cytokine; Histone acetyltransferase; Inflammation; Neurotoxicity; Nuclear factor B; P300 CBP associated factor

Indexed keywords

BETA SECRETASE; CARBON 11; E1A ASSOCIATED P300 PROTEIN; HISTONE ACETYLTRANSFERASE GCN5; HISTONE ACETYLTRANSFERASE PCAF; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

ACETYLATION; ARTICLE; BINDING AFFINITY; CELL DEATH; CELL MEDIATED CYTOTOXICITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; IC 50; MICROGLIA; MOLECULAR DOCKING; NEUROTOXICITY; PRIORITY JOURNAL; WESTERN BLOTTING;

ACETYLATION; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; CELL DEATH; COMPUTER SIMULATION; DRUG DISCOVERY; ENZYME ACTIVATION; MICE; MICROGLIA; MODELS, MOLECULAR; MOLECULAR CONFORMATION; NEURONS; NF-KAPPA B; P300-CBP TRANSCRIPTION FACTORS; SMALL MOLECULE LIBRARIES;

EID: 84879374422     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2013.1407     Document Type: Article

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