Improved synthesis of the C16-C20 segment of resolvin E1 using enantioselective ketone reduction and lipase-catalyzed resolution

Organic Process Research and Development

Volumn 17, Issue 6, 2013, Pages 915-920

  Amin, Rasidul ^a   Chen, Jian Xie ^b   Cotterill, Ian C ^a   Emrich, Daniel ^b   Ganley, Daniel ^b   Khmelnitsky, Yuri L ^a   Mclaws, Mark D ^a   Michels, Peter C ^a   Schwartz, C Eric ^c,d   Thomas, Deb ^b   Yan, Jun ^a   Yang, Qiang ^a  

^a ALBANY MOLECULAR RESEARCH INC   (United States)

^b Chemical Development   (United States)

^c Resolvyx Pharmaceuticals   (United States)

^d Avila Therapeutics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENANTIOSELECTIVE; ENDOGENOUS METABOLITES; HYDROXYL GROUPS; KETONE REDUCTION; LIPASE-CATALYZED; LIPASE-CATALYZED RESOLUTION; SONOGASHIRA COUPLING; THERAPEUTIC AGENTS;

ACETYLATION; KETONES;

CATALYSIS;

EID: 84879350065     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op4000384     Document Type: Article

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