Personalized cytomic assessment of vascular health: Evaluation of the vascular health profile in diabetes mellitus

Cytometry Part B - Clinical Cytometry

Volumn 84, Issue 4, 2013, Pages 255-266

  Kurtzman, Nicholas ^a   Zhang, Lifeng ^b   French, Benjamin ^a   Jonas, Rebecca ^b   Bantly, Andrew ^a   Rogers, Wade T ^a   Moore, Jonni S ^a   Rickels, Michael R ^b   Mohler, Emile R ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

circulating progenitor cell; cytometric fingerprinting; diagnostic testing; microparticle; type 2 diabetes mellitus

Indexed keywords

CD31 ANTIGEN; CELL SURFACE MARKER; FIBRINOGEN RECEPTOR; VASCULOTROPIN RECEPTOR 2;

ADULT; AGED; ANALYTIC METHOD; ARTICLE; ATHEROSCLEROSIS; BLOOD VESSEL FUNCTION; CARDIOVASCULAR PARAMETERS; CELL DAMAGE; CLINICAL ASSESSMENT; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOMETRIC FINGERPRINTING; DIABETES MELLITUS; DIABETIC PATIENT; FEMALE; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELL; HUMAN; INFLAMMATION; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PERSONALIZED MEDICINE; PHENOTYPE; PRIORITY JOURNAL; THROMBOSIS; VASCULAR HEALTH PROFILE; VASCULARIZATION;

AGED; CELL-DERIVED MICROPARTICLES; DIABETES MELLITUS; DIABETIC ANGIOPATHIES; ENDOTHELIUM, VASCULAR; FEMALE; FLOW CYTOMETRY; HUMANS; INDIVIDUALIZED MEDICINE; MALE; MIDDLE AGED; STEM CELLS;

EID: 84879347577     PISSN: 15524949     EISSN: 15524957     Source Type: Journal    
DOI: 10.1002/cyto.b.21095     Document Type: Article

References (44)

1. Heidenreich PA, Trogdon JG, Khavjou OA, Butler J, Dracup K, Ezekowitz MD, Finkelstein EA, Hong Y, Johnston SC, Khera A, et al. Forecasting the future of cardiovascular disease in the United States: A policy statement from the American Heart Association. Circulation 2011; 123: 933-944.
2. Möbius-Winkler S, Höllriegel R, Schuler G, Adams V,. Endothelial progenitor cells: Implications for cardiovascular disease. Cytometry A 2009; 75A: 25-37.
3. Asahara T, Murohara T, Sullivan A, Silver M, van der Zee R, Li T, Witzenbichler B, Schatteman G, Isner JM,. Isolation of putative progenitor endothelial cells for angiogenesis. Science 1997; 275: 964-967.
4. Ouma GO, Jonas RA, Usman MH, Mohler ER III,. Targets and delivery methods for therapeutic angiogenesis in peripheral artery disease. Vasc Med 2012; 17: 174-192.
5. Tushuizen ME, Diamant M, Sturk A, Nieuwland R,. Cell-Derived microparticles in the pathogenesis of cardiovascular disease. Arterioscler Throm Vasc Biol 2011; 31: 4-9.
6. Macey MG, Enniks N, Bevan S,. Flow cytometric analysis of microparticle phenotype and their role in thrombin generation. Cytometry B Clin Cytom 2011; 80B: 57-63.
7. Curtis AM, Zhang L, Medenilla E, Gui M, Wilkinson PF, Hu E, Giri J, Doraiswamy V, Gunda S, Burgert ME, et al. Relationship of microparticles to progenitor cells as a measure of vascular health in a diabetic population. Cytometry B Clin Cytom 2010; 78B: 329-337.
8. Pirro M, Schillaci G, Paltriccia R, Bagaglia F, Menecali C, Mannarino MR, Capanni M, Velardi A, Mannarino E,. Increased ratio of CD31+/CD42- Microparticles to endothelial progenitors as a novel marker of atherosclerosis in hypercholesterolemia. Arterioscler Throm Vasc Biol 2006; 26: 2530-2535.
9. Preffer F, Dombkowski D,. Advances in complex multiparameter flow cytometry technology: Applications in stem cell research. Cytometry B Clin Cytom 2009; 76B: 295-314.
10. Rogers WT, Moser AR, Holyst HA, Bantly A, Mohler ER, Scangas G, Moore JS,. Cytometric fingerprinting: Quantitative characterization of multivariate distributions. Cytometry A 2008; 73A: 430-441.
11. Rogers WT, Holyst HA,. FlowFP: A bioconductor package for fingerprinting flow cytometric data. Adv Bioinformatics 2009: 193947. DOI: 10.1155/2009/193947.
12. Boscolo R, Liao JC, Roychowdhury VP,. An information theoretic exploratory method for learning patterns of conditional gene coexpression from microarray data. IEEE/ACM Trans Comput Biol Bioinform 2008; 5: 15-24.
13. Döring Y, Noels H, Weber C,. The use of high-throughput technologies to investigate vascular inflammation and atherosclerosis. Arterioscler Throm Vasc Biol 2012; 32: 182-195.
14. Beckman JA, Creager MA, Libby P,. Diabetes and atherosclerosis. JAMA 2002; 287: 2570-2581.
15. Lombardo MF, Iacopino P, Cuzzola M, Spiniello E, Garreffa C, Ferrelli F, Coppola A, Saccardi R, Piaggesi A, Piro R, et al. Type 2 diabetes mellitus impairs the maturation of endothelial progenitor cells and increases the number of circulating endothelial cells in peripheral blood. Cytometry A 2012; 81A: 856-864.
16. Roederer M,. Spectral compensation for flow cytometry: Visualization artifacts, limitations, and caveats. Cytometry 2001; 45: 194-205.
17. Khan SS, Solomon MA, McCoy JP Jr,. Detection of circulating endothelial cells and endothelial progenitor cells by flow cytometry. Cytometry B Clin Cytom 2005; 64B: 1-8.
18. Holyst HA, Rogers WT,. FlowFP: Fingerprinting for flow cytometry. 1.12.1. Bioconductor package version 1.18.0; 2009.
19. Ellis B, Haaland P, Hahne F, Le Meur N, Gopalakrishnan N,. FlowCore: Basic structures for flow cytometry data. Bioconductor package version 1.18.0; 2009.
20. Wand M,. KernSmooth: Functions for kernel smoothing for Wand & Jones (1995). KernSmooth version 2.23-6; 2011.
21. R Development Core Team. R: A Language and Environment for Statistical Computing. Vienna, Austria: R Foundation for Statistical Computing; 2011.
22. Fadini GP, Losordo D, Dimmeler S,. Critical reevaluation of endothelial progenitor cell phenotypes for therapeutic and diagnostic use. Circ Res 2012; 110: 624-637.
23. Mund JA, Case J,. The ontogeny of endothelial progenitor cells through flow cytometry. Curr Opin Hematol 2011; 18: 166-170.
24. Shaffer RG, Greene S, Arshi A, Supple G, Bantly A, Moore JS, Mohler ER,. Flow cytometric measurement of circulating endothelial cells: The effect of age and peripheral arterial disease on baseline levels of mature and progenitor populations. Cytometry B Clin Cytom 2006; 70B: 56-62.
25. Estes ML, Mund JA, Mead LE, Prater DN, Cai S, Wang H, Pollok KE, Murphy MP, An CST, Srour EF, et al. Application of polychromatic flow cytometry to identify novel subsets of circulating cells with angiogenic potential. Cytometry A 2010; 77A: 831-839.
26. Pradhan KR, Mund JA, Johnson C, Vik TA, Ingram DA, Case J,. Polychromatic flow cytometry identifies novel subsets of circulating cells with angiogenic potential in pediatric solid tumors. Cytometry B Clin Cytom 2011; 80B: 335-338.
27. Abaci A, Kahraman S, Eryol NK, Arinç H, Ergin A,. Effect of diabetes mellitus on formation of coronary collateral vessels. Circulation 1999; 99: 2239-2242.
28. Mause SF, Weber C,. Microparticles. Circ Res 2010; 107: 1047-1057.
29. Macey MG, Enniks N, Bevan S,. Flow cytometric analysis of microparticle phenotype and their role in thrombin generation. Cytometry B Clin Cytom 2011; 80B: 57-63.
30. Chironi G, Simon A, Hugel B, Del Pino M, Gariepy J, Freyssinet J-M, Tedgui A,. Circulating leukocyte-derived microparticles predict subclinical atherosclerosis burden in asymptomatic subjects. Arterioscler Throm Vasc Biol 2006; 26: 2775-2780.
31. Bernal-Mizrachi L, Jy W, Jimenez JJ, Pastor J, Mauro LM, Horstman LL, de Marchena E, Ahn YS,. High levels of circulating endothelial microparticles in patients with acute coronary syndromes. Am Heart J 2003; 145: 962-970.
32. Sinning J-M, Losch J, Walenta K, Böhm M, Nickenig G, Werner N,. Circulating CD31+/Annexin V+ microparticles correlate with cardiovascular outcomes. Eur Heart J 2011; 32: 2034-2041.
33. Jung KH, Chu K, Lee ST, Park HK, Bahn JJ, Kim DH, Kim JH, Kim M, Kun Lee S, Roh JK,. Circulating endothelial microparticles as a marker of cerebrovascular disease. Ann Neurol 2009; 66: 191-199.
34. Koga H, Sugiyama S, Kugiyama K, Watanabe K, Fukushima H, Tanaka T, Sakamoto T, Yoshimura M, Jinnouchi H, Ogawa H,. Elevated levels of VE-Cadherin-positive endothelial microparticles in patients with type 2 diabetes mellitus and coronary artery disease. J Am Coll Cardiol 2005; 45: 1622-1630.
35. Omoto S, Nomura S, Shouzu A, Hayakawa T, Shimizu H, Miyake Y, Yonemoto T, Nishikawa M, Fukuhara S, Inada M,. Significance of platelet-derived microparticles and activated platelets in diabetic nephropathy. Nephron 1999; 81: 271-277.
36. Tan KT, Tayebjee MH, Lim HS, Lip GYH,. Clinically apparent atherosclerotic disease in diabetes is associated with an increase in platelet microparticle levels. Diab Med 2005; 22: 1657-1662.
37. Kim HK, Song KS, Chung J-H, Lee KR, Lee S-N,. Platelet microparticles induce angiogenesis in vitro. Br J Haematol 2004; 124: 376-384.
38. Mause SF, Ritzel E, Liehn EA, Hristov M, Bidzhekov K, Müller-Newen G, Soehnlein O, Weber C,. Platelet microparticles enhance the vasoregenerative potential of angiogenic early outgrowth cells after vascular injury. Circulation 2010; 122: 495-506.
39. Chironi G, Boulanger C, Simon A, Dignat-George F, Freyssinet J-M, Tedgui A,. Endothelial microparticles in diseases. Cell Tissue Res 2009; 335: 143-151.
40. Feng B, Chen Y, Luo Y, Chen M, Li X, Ni Y,. Circulating level of microparticles and their correlation with arterial elasticity and endothelium-dependent dilation in patients with type 2 diabetes mellitus. Atherosclerosis 2010; 208: 5.
41. Singh N, Van Craeyveld E, Tjwa M, Ciarka A, Emmerechts J, Droogne W, Gordts SC, Carlier V, Jacobs F, Fieuws S, et al. Circulating apoptotic endothelial cells and apoptotic endothelial microparticles independently predict the presence of cardiac allograft vasculopathy. J Am Coll Cardiol 2012; 60: 324-331.
42. Martin S, Tesse A, Hugel B, Martínez MC, Morel O, Freyssinet J-M, Andriantsitohaina R,. Shed membrane particles from T lymphocytes impair endothelial function and regulate endothelial protein expression. Circulation 2004; 109: 1653-1659.
43. Mallat Z, Hugel B, Ohan J, Lesèche G, Freyssinet J-M, Tedgui A,. Shed membrane microparticles with procoagulant potential in human atherosclerotic plaques: A role for apoptosis in plaque thrombogenicity. Circulation 1999; 99: 348-353.
44. Mallat Z, Benamer H, Hugel B, Benessiano J, Steg PG, Freyssinet J-M, Tedgui A,. Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes. Circulation 2000; 101: 841-843.