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Volumn 32, Issue 2, 2013, Pages 464-468

TGF-β1 induces the dissolution of tight junctions in human renal proximal tubular cells: Role of the RhoA/ROCK signaling pathway

Author keywords

Epithelial Mesenchymal Transition; Renal Fibrosis; Rho Rock Signaling Pathway; Tight Junctions; Transforming Growth Factor 1

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; OCCLUDIN; PROTEIN ZO1; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84879339562     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2013.1396     Document Type: Article
Times cited : (41)

References (28)
  • 1
    • 37849189626 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and its implications for the development of renal tubulointerstitial fibrosis
    • Rastaldi MP: Epithelial-mesenchymal transition and its implications for the development of renal tubulointerstitial fibrosis. J Nephrol 19: 407-412, 2006. (Pubitemid 44823195)
    • (2006) Journal of Nephrology , vol.19 , Issue.4 , pp. 407-412
    • Rastaldi, M.P.1
  • 2
    • 36148979331 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition in the progression of tubulointerstitial fibrosis
    • Li MX and Liu BC: Epithelial to mesenchymal transition in the progression of tubulointerstitial fibrosis. Chinese Med J 120: 1925-1930, 2007.
    • (2007) Chinese Med J , vol.120 , pp. 1925-1930
    • Li, M.X.1    Liu, B.C.2
  • 3
    • 82355190219 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of renal fibrosis
    • Liu Y: Cellular and molecular mechanisms of renal fibrosis. Nat Rev 7: 684-696, 2011.
    • (2011) Nat Rev , vol.7 , pp. 684-696
    • Liu, Y.1
  • 5
    • 14844364701 scopus 로고    scopus 로고
    • Regulation of the polarity protein Par6 by TGFβ receptors controls epithelial cell plasticity
    • DOI 10.1126/science.1105718
    • Ozdamar B, Bose R, Barrios-Rodiles M, Wang HR, Zhang Y and Wrana JL: Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity. Science 307: 1603-1609, 2005. (Pubitemid 40354739)
    • (2005) Science , vol.307 , Issue.5715 , pp. 1603-1609
    • Ozdamar, B.1    Bose, R.2    Barrios-Rodiles, M.3    Wang, H.-R.4    Zhang, Y.5    Wrana, J.L.6
  • 6
    • 79951793466 scopus 로고    scopus 로고
    • Role Of Smad23 and P38 MAP kinase in TGF-beta1-induced epithelial-mesenchymal transition of pulmonary epithelial cells
    • Kolosova I, Nethery D and Kern JA: Role of Smad2/3 and p38 MAP kinase in TGF-beta1-induced epithelial-mesenchymal transition of pulmonary epithelial cells. J Cell Physiol 226: 1248-1254, 2011.
    • (2011) J Cell Physiol , vol.226 , pp. 1248-1254
    • Kolosova, I.1    Nethery, D.2    Kern, J.A.3
  • 8
    • 79960901978 scopus 로고    scopus 로고
    • The role of the p38 MAPK signaling pathway in high glucoseinduced epithelial-mesenchymal transition of cultured human renal tubular epithelial cells
    • Lv ZM, Wang Q, Wan Q, Lin JG, Hu MS, Liu YX and Wang R: The role of the p38 MAPK signaling pathway in high glucoseinduced epithelial-mesenchymal transition of cultured human renal tubular epithelial cells. PloS One 6: E22806, 2011.
    • (2011) PloS One , vol.6
    • Lv, Z.M.1    Wang, Q.2    Wan, Q.3    Lin, J.G.4    Hu, M.S.5    Liu, Y.X.6    Wang, R.7
  • 9
    • 80755187843 scopus 로고    scopus 로고
    • Smad phosphoisoform signaling specificity: The right place at the right time
    • Matsuzaki K: Smad phosphoisoform signaling specificity: The right place at the right time. Carcinogenesis 32: 1578-1588, 2011.
    • (2011) Carcinogenesis , vol.32 , pp. 1578-1588
    • Matsuzaki, K.1
  • 10
    • 84857995001 scopus 로고    scopus 로고
    • Inhibition of actin dynamics during epithelial-to-mesenchymal transition
    • Schneider D and Janshoff A: Inhibition of actin dynamics during epithelial-to-mesenchymal transition. Biochem Biophys Res Commun 419: 221-225, 2012.
    • (2012) Biochem Biophys Res Commun , vol.419 , pp. 221-225
    • Schneider, D.1    Janshoff, A.2
  • 12
    • 79952249814 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition of rat peritoneal mesothelial cells via Rhoa/Rock pathway
    • Zhang H, Liu X, Liu Y, Yi B and Yu X: Epithelial-mesenchymal transition of rat peritoneal mesothelial cells via Rhoa/Rock pathway. In Vitro Cell Dev Biol 47: 165-172, 2010.
    • (2010) Vitro Cell Dev Biol , vol.47 , pp. 165-172
    • Zhang, H.1    Liu, X.2    Liu, Y.3    Yi, B.4    Yu, X.5
  • 13
    • 34548074403 scopus 로고    scopus 로고
    • Effect of TGF-beta1 stimulation on the smad signal transduction pathway of human peritoneal mesothelial cells
    • (In Chinese).
    • Zhang H, Liu FY and Liu YH: Effect of TGF-beta1 stimulation on the smad signal transduction pathway of human peritoneal mesothelial cells. Zhong Nan Da Xue Xue Bao Yi Xue Ban 29: 142-147, 2004 (In Chinese).
    • (2004) Zhong Nan Da Xue Xue Bao Yi Xue Ban , vol.29 , pp. 142-147
    • Zhang, H.1    Liu, F.Y.2    Liu, Y.H.3
  • 15
    • 36248990744 scopus 로고    scopus 로고
    • Transforming growth factor beta mediates hepatocyte apoptosis through Smad3 generation of reactive oxygen species
    • DOI 10.1016/j.biochi.2007.09.001, PII S030090840700243X
    • Black D, Lyman S, Qian T, Lemasters JJ, Rippe RA, Nitta T, Kim JS and Behrns KE: Transforming growth factor beta mediates hepatocyte apoptosis through Smad3 generation of reactive oxygen species. Biochimie 89: 1464-1473, 2007. (Pubitemid 350122858)
    • (2007) Biochimie , vol.89 , Issue.12 , pp. 1464-1473
    • Black, D.1    Lyman, S.2    Qian, T.3    Lemasters, J.J.4    Rippe, R.A.5    Nitta, T.6    Kim, J.-S.7    Behrns, K.E.8
  • 17
    • 67349173648 scopus 로고    scopus 로고
    • Transforming growth factor-beta signaling alters substrate permeability and tight junction protein expression at the blood-brain barrier during inflammatory pain
    • Ronaldson PT, Demarco KM, Sanchez-Covarrubias L, Solinsky CM and Davis TP: Transforming growth factor-beta signaling alters substrate permeability and tight junction protein expression at the blood-brain barrier during inflammatory pain. J Cereb Blood Flow Metab 29: 1084-1098, 2009.
    • (2009) J Cereb Blood Flow Metab , vol.29 , pp. 1084-1098
    • Ronaldson, P.T.1    Demarco, K.M.2    Sanchez-Covarrubias, L.3    Solinsky, C.M.4    Davis, T.P.5
  • 20
    • 77954889407 scopus 로고    scopus 로고
    • Serine 34 phosphorylation of rho guanine dissociation inhibitor (RhoGDIalpha) links signaling from conventional protein kinase C to RhoGTPase in cell adhesion
    • Dovas A, Choi Y, Yoneda A, Multhaupt HA, Kwon SH, Kang D, Oh ES and Couchman JR: Serine 34 phosphorylation of rho guanine dissociation inhibitor (RhoGDIalpha) links signaling from conventional protein kinase C to RhoGTPase in cell adhesion. J Biol Chem 285: 23296-23308, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 23296-23308
    • Dovas, A.1    Choi, Y.2    Yoneda, A.3    Multhaupt, H.A.4    Kwon, S.H.5    Kang, D.6    Oh, E.S.7    Couchman, J.R.8
  • 22
    • 0036197606 scopus 로고    scopus 로고
    • Transforming growth factor-β-induced mobilization of actin cytoskeleton requires signaling by small GTPases Cdc42 and RhoA
    • DOI 10.1091/mbc.01-08-0398
    • Edlund S, Landstrom M, Heldin CH and Aspenstrom P: Transforming growth factor-beta-induced mobilization of actin cytoskeleton requires signaling by small GTPases Cdc42 and RhoA. Mol Biol Cell 13: 902-914, 2002. (Pubitemid 34250354)
    • (2002) Molecular Biology of the Cell , vol.13 , Issue.3 , pp. 902-914
    • Edlund, S.1    Landstrom, M.2    Heldin, C.-H.3    Aspenstrom, P.4
  • 23
    • 0347930678 scopus 로고    scopus 로고
    • FGF-2 induced reorganization and disruption of actin cytoskeleton through PI 3-kinase, Rho, and Cdc42 in corneal endothelial cells
    • Lee HT and Kay EP: FGF-2 induced reorganization and disruption of actin cytoskeleton through PI 3-kinase, Rho, and Cdc42 in corneal endothelial cells. Mol Vision 9: 624-634, 2003. (Pubitemid 38097628)
    • (2003) Molecular Vision , vol.9 , pp. 624-634
    • Lee, H.T.1    Kay, E.P.2
  • 25
    • 78649680349 scopus 로고    scopus 로고
    • Thrombin promotes actin stress fiber formation in RPE through Rho/ROCK-mediated MLC phosphorylation
    • Ruiz-Loredo AY, Lopez E and Lopez-Colome AM: Thrombin promotes actin stress fiber formation in RPE through Rho/ROCK-mediated MLC phosphorylation. J Cell Physiol 226: 414-423, 2011.
    • (2011) J Cell Physiol , vol.226 , pp. 414-423
    • Ruiz-Loredo, A.Y.1    Lopez, E.2    Lopez-Colome, A.M.3
  • 26
    • 77954347824 scopus 로고    scopus 로고
    • Interleukin-1 receptor phosphorylation activates rho kinase to disrupt human gastric tight junctional claudin-4 during helicobacter pylori infection
    • Lapointe TK, O'Connor PM, Jones NL, Menard D and Buret AG: Interleukin-1 receptor phosphorylation activates Rho kinase to disrupt human gastric tight junctional claudin-4 during Helicobacter pylori infection. Cell Microbiol 12: 692-703, 2010.
    • (2010) Cell Microbiol , vol.12 , pp. 692-703
    • Lapointe, T.K.1    O'Connor, P.M.2    Jones, N.L.3    Menard, D.4    Buret, A.G.5
  • 28
    • 3242705077 scopus 로고    scopus 로고
    • RhoA, Rac1, and Cdc42 exert distinct effects on epithelial barrier via selective structural and biochemical modulation of junctional proteins and F-actin
    • DOI 10.1152/ajpcell.00087.2004
    • Bruewer M, Hopkins AM, Hobert ME, Nusrat A and Madara JL: RhoA, Rac1, and Cdc42 exert distinct effects on epithelial barrier via selective structural and biochemical modulation of junctional proteins and F-actin. Am J Physiol 287: C327-C335, 2004. (Pubitemid 38955223)
    • (2004) American Journal of Physiology - Cell Physiology , vol.287 , Issue.2
    • Bruewer, M.1    Hopkins, A.M.2    Hobert, M.E.3    Nusrat, A.4    Madara, J.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.