CCR2 deficiency, dysregulation of notch signaling, and spontaneous pulmonary arterial hypertension

American Journal of Respiratory Cell and Molecular Biology

Volumn 48, Issue 5, 2013, Pages 647-654

  Yu, Yen Rei A ^a   Mao, Lan ^a   Piantadosi, Claude A ^a   Gunn, Michael D ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

C C chemokine type 2 receptor; Delta like 4; Jagged 1; Notch 3; Pulmonary arterial hypertension

Indexed keywords

CHEMOKINE RECEPTOR CCR2; NOTCH3 RECEPTOR; CALCIUM BINDING PROTEIN; CCR2 PROTEIN, MOUSE; DLK1 PROTEIN, MOUSE; DLL4 PROTEIN, MOUSE; JAG2 PROTEIN, MOUSE; MEMBRANE PROTEIN; NOTCH RECEPTOR; NOTCH3 PROTEIN, MOUSE; SERRATE PROTEINS; SIGNAL PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE RESPONSE; DISEASE SEVERITY; ESSENTIAL HYPERTENSION; HEART RIGHT VENTRICLE HYPERTROPHY; HEART RIGHT VENTRICLE PRESSURE; HYPOXIA; LEUKOCYTE MIGRATION; LUNG BLOOD VESSEL; MALE; MOUSE; NEWBORN; NONHUMAN; PATHOPHYSIOLOGY; PHENOTYPE; PROTEIN EXPRESSION; PULMONARY ARTERY; PULMONARY HYPERTENSION; SIGNAL TRANSDUCTION; SYSTOLIC BLOOD PRESSURE; TACHYCARDIA; WILD TYPE; ANIMAL; ANOXIA; ARTERIOLE; C57BL MOUSE; DENDRITIC CELL; GENETICS; IMMUNOLOGY; LUNG; MACROPHAGE; METABOLISM; MOUSE MUTANT; PATHOLOGY; VASCULAR SMOOTH MUSCLE; VASCULARIZATION;

ANIMALS; ANOXIA; ARTERIOLES; CALCIUM-BINDING PROTEINS; DENDRITIC CELLS; HYPERTENSION, PULMONARY; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LUNG; MACROPHAGES; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; RECEPTORS, CCR2; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

MLCS; MLOWN;

EID: 84879311171     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2012-0182OC     Document Type: Article

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