-
1
-
-
77952117909
-
Analysis of Food and Drug Administration-approved anticancer agents in the NCI60 panel of human tumor cell lines
-
Holbeck SL, Collins JM, Doroshow JH. Analysis of Food and Drug Administration-approved anticancer agents in the NCI60 panel of human tumor cell lines. Mol Cancer Ther 2010;9:1451-60.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 1451-1460
-
-
Holbeck, S.L.1
Collins, J.M.2
Doroshow, J.H.3
-
2
-
-
33845200848
-
Mutation analysis of 24 known cancer genes in the NCI-60 cell line set
-
Ikediobi ON, Davies H, Bignell G, Edkins S, Stevens C, O'Meara S, et al. Mutation analysis of 24 known cancer genes in the NCI-60 cell line set. Mol Cancer Ther 2006;5:2606-12.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2606-2612
-
-
Ikediobi, O.N.1
Davies, H.2
Bignell, G.3
Edkins, S.4
Stevens, C.5
O'Meara, S.6
-
3
-
-
8444227084
-
Transcription profiling of gene expression in drug discovery and development: The NCI experience
-
Sausville EA, Holbeck SL. Transcription profiling of gene expression in drug discovery and development: the NCI experience. Eur J Cancer 2004;40:2544-9.
-
(2004)
Eur J Cancer
, vol.40
, pp. 2544-2549
-
-
Sausville, E.A.1
Holbeck, S.L.2
-
4
-
-
21844478747
-
Integrative genomic analyses identify MITF as a lineage survival oncogeneamplified in malignant melanoma
-
Garraway LA, Widlund HR, Rubin MA, Getz G, Berger AJ, Ramaswamy S, et al. Integrative genomic analyses identify MITF as a lineage survival oncogeneamplified in malignant melanoma. Nature 2005;436:117-22.
-
(2005)
Nature
, vol.436
, pp. 117-122
-
-
Garraway, L.A.1
Widlund, H.R.2
Rubin, M.A.3
Getz, G.4
Berger, A.J.5
Ramaswamy, S.6
-
5
-
-
34250697605
-
MicroRNA expression profiles for the NCI-60 cancer cell panel
-
Blower PE, Verducci JS, Lin S, Zhou J, Chung JH, Dai Z, et al. MicroRNA expression profiles for the NCI-60 cancer cell panel. Mol Cancer Ther 2007;6:1483-91.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1483-1491
-
-
Blower, P.E.1
Verducci, J.S.2
Lin, S.3
Zhou, J.4
Chung, J.H.5
Dai, Z.6
-
6
-
-
10744226821
-
Proteomic profiling of the NCI-60 cancer cell lines using new high-density reverse-phase lysate microarrays
-
Nishizuka S, Charboneau L, Young L, Major S, Reinhold WC, Waltham M, et al. Proteomic profiling of the NCI-60 cancer cell lines using new high-density reverse-phase lysate microarrays. Proc Natl Acad Sci U S A 2003;100:14229-34.
-
(2003)
Proc Natl Acad Sci u S A
, vol.100
, pp. 14229-14234
-
-
Nishizuka, S.1
Charboneau, L.2
Young, L.3
Major, S.4
Reinhold, W.C.5
Waltham, M.6
-
7
-
-
0347951257
-
Karyotypic complexity of the NCI-60 drug-screening panel
-
Roschke AV, Tonon G, Gehlhaus KS, McTyre N, Bussey KJ, Lababidi S, et al. Karyotypic complexity of the NCI-60 drug-screening panel. Cancer Res 2003;63:8634-47.
-
(2003)
Cancer Res
, vol.63
, pp. 8634-8647
-
-
Roschke, A.V.1
Tonon, G.2
Gehlhaus, K.S.3
McTyre, N.4
Bussey, K.J.5
Lababidi, S.6
-
8
-
-
0031003434
-
A protein expression database for the molecular pharmacology of cancer
-
Myers TG, Anderson NL, Waltham M, Li G, Buolamwini JK, Scudiero DA, et al. A protein expression database for the molecular pharmacology of cancer. Electrophoresis 1997;18:647-53.
-
(1997)
Electrophoresis
, vol.18
, pp. 647-653
-
-
Myers, T.G.1
Anderson, N.L.2
Waltham, M.3
Li, G.4
Buolamwini, J.K.5
Scudiero, D.A.6
-
9
-
-
79959966646
-
Protein pathway activation mapping of brain metastasis from lung and breast cancers reveals organ type specific drug target activation
-
Improta G, Zupa A, Fillmore H, Deng J, Aieta M, Musto P, et al. Protein pathway activation mapping of brain metastasis from lung and breast cancers reveals organ type specific drug target activation. J Proteome Res 2011;10:3089-97.
-
(2011)
J Proteome Res
, vol.10
, pp. 3089-3097
-
-
Improta, G.1
Zupa, A.2
Fillmore, H.3
Deng, J.4
Aieta, M.5
Musto, P.6
-
10
-
-
76649106091
-
Integrative analysis of proteomic signatures, mutations, and drug responsiveness in the NCI 60 cancer cell line set
-
Park ES, Rabinovsky R, Carey M, Hennessy BT, Agarwal R, Liu W, et al. Integrative analysis of proteomic signatures, mutations, and drug responsiveness in the NCI 60 cancer cell line set. Mol Cancer Ther 2010;9:257-67.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 257-267
-
-
Park, E.S.1
Rabinovsky, R.2
Carey, M.3
Hennessy, B.T.4
Agarwal, R.5
Liu, W.6
-
11
-
-
84879310451
-
-
Accessed 4/26/2013
-
Available from: http://discover.nci.nih.gov/cellminer/. Accessed 4/26/2013.
-
-
-
-
12
-
-
84879291048
-
-
Accessed 4/26/2013
-
Available from: http://dtp.nci.nih.gov. Accessed 4/26/2013.
-
-
-
-
13
-
-
33947305781
-
ARACNE: An algorithm for the reconstruction of gene regulatory networks in a mammalian cellular context
-
Margolin AA, Nemenman I, Basso K, Wiggins C, Stolovitzky G, Dalla Favera R, et al. ARACNE: an algorithm for the reconstruction of gene regulatory networks in a mammalian cellular context. BMC Bioinfor-matics 2006;7 Suppl 1:S7.
-
(2006)
BMC Bioinfor-matics
, vol.7
, Issue.SUPPL. 1
-
-
Margolin, A.A.1
Nemenman, I.2
Basso, K.3
Wiggins, C.4
Stolovitzky, G.5
Dalla Favera, R.6
-
14
-
-
33846400424
-
Large-scale mapping and validation of Escherichia coli transcriptional regulation from a compendium of expression profiles
-
Faith JJ, Hayete B, Thaden JT, Mogno I, Wierzbowski J, Cottarel G, et al. Large-scale mapping and validation of Escherichia coli transcriptional regulation from a compendium of expression profiles. PLoS Biol 2007;5:e8.
-
(2007)
PLoS Biol
, vol.5
-
-
Faith, J.J.1
Hayete, B.2
Thaden, J.T.3
Mogno, I.4
Wierzbowski, J.5
Cottarel, G.6
-
16
-
-
77957141016
-
Inferring the conservative causal core of gene regulatory networks
-
Altay G, Emmert-Streib F. Inferring the conservative causal core of gene regulatory networks. BMC Syst Biol 2010;4:132.
-
(2010)
BMC Syst Biol
, vol.4
, pp. 132
-
-
Altay, G.1
Emmert-Streib, F.2
-
17
-
-
77958570788
-
Inferring regulatory networks from expression data using tree-based methods
-
Huynh-Thu VA, Irrthum A, Wehenkel L, Geurts P. Inferring regulatory networks from expression data using tree-based methods. PLoS ONE 2010;5.
-
(2010)
PLoS ONE
, pp. 5
-
-
Huynh-Thu, V.A.1
Irrthum, A.2
Wehenkel, L.3
Geurts, P.4
-
18
-
-
84868340988
-
Multiplexed protein signal pathway mapping identifies patients with rectal cancer that responds to neoadjuvant treatment
-
Mammano E, Galdi F, Pierobon M, Tessari E, Deng J, Pucciarelli S, et al. Multiplexed protein signal pathway mapping identifies patients with rectal cancer that responds to neoadjuvant treatment. Clin Colorectal Cancer 2012;11:268-74.
-
(2012)
Clin Colorectal Cancer
, vol.11
, pp. 268-274
-
-
Mammano, E.1
Galdi, F.2
Pierobon, M.3
Tessari, E.4
Deng, J.5
Pucciarelli, S.6
-
19
-
-
79953207329
-
Mammalian Hippo pathway: From development to cancer and beyond
-
Bao Y, Hata Y, Ikeda M, Withanage K. Mammalian Hippo pathway: from development to cancer and beyond. J Biochem 2011;149:361-79.
-
(2011)
J Biochem
, vol.149
, pp. 361-379
-
-
Bao, Y.1
Hata, Y.2
Ikeda, M.3
Withanage, K.4
-
20
-
-
39849097306
-
The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals
-
Zeng Q, Hong W. The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals. Cancer Cell 2008;13:188-92.
-
(2008)
Cancer Cell
, vol.13
, pp. 188-192
-
-
Zeng, Q.1
Hong, W.2
-
21
-
-
77952307133
-
MicroRNA-204/211 alters epithelial physiology
-
Wang FE, Zhang C, Maminishkis A, Dong L, Zhi C, Li R, et al. MicroRNA-204/211 alters epithelial physiology. FASEB J 2010;24: 1552-71.
-
(2010)
FASEB J
, vol.24
, pp. 1552-1571
-
-
Wang, F.E.1
Zhang, C.2
Maminishkis, A.3
Dong, L.4
Zhi, C.5
Li, R.6
-
22
-
-
84864886346
-
Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding
-
Ptasinska A, Assi SA, Mannari D, James SR, Williamson D, Dunne J, et al. Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding. Leukemia 2012;26:1829-41.
-
(2012)
Leukemia
, vol.26
, pp. 1829-1841
-
-
Ptasinska, A.1
Assi, S.A.2
Mannari, D.3
James, S.R.4
Williamson, D.5
Dunne, J.6
-
23
-
-
35649014941
-
The pro-apoptotic kinase Mst1 and its caspase cleavage products are direct inhibitors of Akt1
-
Cinar B, Fang PK, Lutchman M, Di Vizio D, Adam RM, Pavlova N, et al. The pro-apoptotic kinase Mst1 and its caspase cleavage products are direct inhibitors of Akt1. EMBO J 2007;26:4523-34.
-
(2007)
EMBO J
, vol.26
, pp. 4523-4534
-
-
Cinar, B.1
Fang, P.K.2
Lutchman, M.3
Di Vizio, D.4
Adam, R.M.5
Pavlova, N.6
-
24
-
-
60749112337
-
YAP: At the crossroad between transformation and tumor suppression
-
Bertini E, Oka T, Sudol M, Strano S, Blandino G. YAP: at the crossroad between transformation and tumor suppression. Cell Cycle 2009;8: 49-57.
-
(2009)
Cell Cycle
, vol.8
, pp. 49-57
-
-
Bertini, E.1
Oka, T.2
Sudol, M.3
Strano, S.4
Blandino, G.5
-
25
-
-
79960031177
-
The HDAC class I-specific inhibitor entinostat (MS-275) effectively relieves epigenetic silencing of the LAT2 gene mediated by AML1/ETO
-
Duque-Afonso J, Yalcin A, Berg T, Abdelkarim M, Heidenreich O, Lubbert M. The HDAC class I-specific inhibitor entinostat (MS-275) effectively relieves epigenetic silencing of the LAT2 gene mediated by AML1/ETO. Oncogene 2011;30:3062-72.
-
(2011)
Oncogene
, vol.30
, pp. 3062-3072
-
-
Duque-Afonso, J.1
Yalcin, A.2
Berg, T.3
Abdelkarim, M.4
Heidenreich, O.5
Lubbert, M.6
-
26
-
-
35649004861
-
Akt phosphorylates MstI and prevents its proteolytic activation, blocking FOXO3 phosphorylation and nuclear translocation
-
Jang SW, Yang SJ, Srinivasan S, Ye K. Akt phosphorylates MstI and prevents its proteolytic activation, blocking FOXO3 phosphorylation and nuclear translocation. J Biol Chem 2007;282:30836-44.
-
(2007)
J Biol Chem
, vol.282
, pp. 30836-30844
-
-
Jang, S.W.1
Yang, S.J.2
Srinivasan, S.3
Ye, K.4
-
27
-
-
84863349211
-
Identification of mechanism that couples multisite phosphorylation of Yes-associated protein (YAP) with transcriptional coactivation and regulation of apoptosis
-
Lee KK, Yonehara S. Identification of mechanism that couples multisite phosphorylation of Yes-associated protein (YAP) with transcriptional coactivation and regulation of apoptosis. J Biol Chem;287:9568-78.
-
J Biol Chem
, vol.287
, pp. 9568-9578
-
-
Lee, K.K.1
Yonehara, S.2
-
28
-
-
43049155951
-
Biosignaling of mammalian Ste20-related kinases
-
Ling P, Lu TJ, Yuan CJ, Lai MD. Biosignaling of mammalian Ste20-related kinases. Cell Signal 2008;20:1237-47.
-
(2008)
Cell Signal
, vol.20
, pp. 1237-1247
-
-
Ling, P.1
Lu, T.J.2
Yuan, C.J.3
Lai, M.D.4
-
29
-
-
79959960788
-
The c-Abl-MST1 signaling pathway mediates oxidative stress-induced neuronal cell death
-
Xiao L, Chen D, Hu P, Wu J, Liu W, Zhao Y, et al. The c-Abl-MST1 signaling pathway mediates oxidative stress-induced neuronal cell death. J Neurosci 2011;31:9611-9.
-
(2011)
J Neurosci
, vol.31
, pp. 9611-9619
-
-
Xiao, L.1
Chen, D.2
Hu, P.3
Wu, J.4
Liu, W.5
Zhao, Y.6
-
30
-
-
79960996763
-
MiR-17/20/93/106 promote hematopoietic cell expansion by targeting sequestosome 1-regulated pathways in mice
-
Meenhuis A, van Veelen PA, de Looper H, van Boxtel N, van den Berge IJ, Sun SM, et al. MiR-17/20/93/106 promote hematopoietic cell expansion by targeting sequestosome 1-regulated pathways in mice. Blood 2011;118:916-25.
-
(2011)
Blood
, vol.118
, pp. 916-925
-
-
Meenhuis, A.1
Van Veelen, P.A.2
De Looper, H.3
Van Boxtel, N.4
Van Den Berge, I.J.5
Sun, S.M.6
-
31
-
-
84861777290
-
Microarray analysis of colorectal cancer stromal tissue reveals upre-gulation of two oncogenic miRNA clusters
-
Nishida N, Nagahara M, Sato T, Mimori K, Sudo T, Tanaka F, et al. Microarray analysis of colorectal cancer stromal tissue reveals upre-gulation of two oncogenic miRNA clusters. Clin Cancer Res 2011; 18:3054-70.
-
(2011)
Clin Cancer Res
, vol.18
, pp. 3054-3070
-
-
Nishida, N.1
Nagahara, M.2
Sato, T.3
Mimori, K.4
Sudo, T.5
Tanaka, F.6
-
32
-
-
84863138752
-
MiR-17-92 cluster regulates cell proliferation and collagen synthesis by targeting TGFβ pathway in mouse palatal mesenchymal cells
-
Li L, Shi JY, Zhu GQ, Shi B. MiR-17-92 cluster regulates cell proliferation and collagen synthesis by targeting TGFβ pathway in mouse palatal mesenchymal cells. J Cell Biochem 2012;113:1235-44.
-
(2012)
J Cell Biochem
, vol.113
, pp. 1235-1244
-
-
Li, L.1
Shi, J.Y.2
Zhu, G.Q.3
Shi, B.4
-
33
-
-
79951810604
-
MicroRNA miR-93 promotes tumor growth and angiogenesis by targeting integ-rin-beta8
-
Fang L, Deng Z, Shatseva T, Yang J, Peng C, Du WW, et al. MicroRNA miR-93 promotes tumor growth and angiogenesis by targeting integ-rin-beta8. Oncogene 2011;30:806-21.
-
(2011)
Oncogene
, vol.30
, pp. 806-821
-
-
Fang, L.1
Deng, Z.2
Shatseva, T.3
Yang, J.4
Peng, C.5
Du, W.W.6
-
34
-
-
84879287366
-
-
Accessed4/26/2013
-
Available from: http://mirdb.org/cgi-bin/search.cgi?searchType= miRNA&full=mirbase&searchBox=MIMAT0000093. Accessed4/26/2013.
-
-
-
-
35
-
-
84875501959
-
PTEN assessment and PI3K/mTOR inhibitors: Importance of simultaneous assessment of MAPK pathway aberrations
-
abstr 10510
-
Janku F, Broaddus R, Bakkar R, Hong DS, Stepanek VMT, Naing A, et al. PTEN assessment and PI3K/mTOR inhibitors: importance of simultaneous assessment of MAPK pathway aberrations. J Clin Oncol 30;2012 (suppl; abstr 10510).
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL.
-
-
Janku, F.1
Broaddus, R.2
Bakkar, R.3
Hong, D.S.4
Stepanek, V.M.T.5
Naing, A.6
-
36
-
-
84865836687
-
The significance of PTEN and AKT aberrations in pediatric T-cell acute lymphoblastic leukemia
-
Zuurbier L, Petricoin EF III, Vuerhard MJ, Calvert V, Kooi C, Buijs-Gladdines JG, et al. The significance of PTEN and AKT aberrations in pediatric T-cell acute lymphoblastic leukemia. Haematologica 2012; 97:1405-13.
-
(2012)
Haematologica
, vol.97
, pp. 1405-1413
-
-
Zuurbier, L.1
Petricoin III, E.F.2
Vuerhard, M.J.3
Calvert, V.4
Kooi, C.5
Buijs-Gladdines, J.G.6
-
37
-
-
54249091564
-
Presenting and exploring biological pathways with PathVisio
-
van Iersel MP, Kelder T, Pico AR, Hanspers K, Coort S, Conklin BR, et al. Presenting and exploring biological pathways with PathVisio. BMC Bioinformatics 2008;9:399.
-
(2008)
BMC Bioinformatics
, vol.9
, pp. 399
-
-
Van Iersel, M.P.1
Kelder, T.2
Pico, A.R.3
Hanspers, K.4
Coort, S.5
Conklin, B.R.6
|