메뉴 건너뛰기




Volumn 126, Issue 12, 2013, Pages 2229-2234

Montelukast improves air trapping, not airway remodeling, in patients with moderate-to-severe asthma: A pilot study

Author keywords

Air trapping; Airway remodeling; Asthma; High resolution computed tomography; Lung function

Indexed keywords

FLUTICASONE PROPIONATE PLUS SALMETEROL XINAFOATE; MONTELUKAST; PLACEBO;

EID: 84879270913     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.20121888     Document Type: Article
Times cited : (17)

References (33)
  • 1
    • 33846017302 scopus 로고    scopus 로고
    • Severe asthma: Lessons from the Severe Asthma Research Program
    • Wenzel SE, Busse WW. Severe asthma: lessons from the Severe Asthma Research Program. J Allergy Clin Immunol 2007; 119: 14-21.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 14-21
    • Wenzel, S.E.1    Busse, W.W.2
  • 2
    • 34247894467 scopus 로고    scopus 로고
    • Global Strategy for Asthma Management and Prevention
    • Accessed June 1, at
    • Global Strategy for Asthma Management and Prevention. Global Initiative for Asthma (GINA). (Accessed June 1, 2012 at: http://www.ginaasthma.org.)
    • (2012) Global Initiative For Asthma (GINA)
  • 3
    • 70349878828 scopus 로고    scopus 로고
    • The role of small airways in monitoring the response to asthma treatment: What is beyond FEV1?
    • Scichilone N, Battaglia S, Olivieri D, Bellia V. The role of small airways in monitoring the response to asthma treatment: what is beyond FEV1? Allergy 2009; 64: 1563-1569.
    • (2009) Allergy , vol.64 , pp. 1563-1569
    • Scichilone, N.1    Battaglia, S.2    Olivieri, D.3    Bellia, V.4
  • 4
    • 79952430815 scopus 로고    scopus 로고
    • The role of small airways in obstructive airway diseases
    • Burgel PR. The role of small airways in obstructive airway diseases. Rur Respir Rev 2011; 20: 23-33.
    • (2011) Rur Respir Rev , vol.20 , pp. 23-33
    • Burgel, P.R.1
  • 5
    • 0034131479 scopus 로고    scopus 로고
    • Recurrent exacerbations in severe asthma are associated with enhanced airway closure during stable episodes
    • In't Veen JC, Beekman AJ, Bel EH, Sterk PJ. Recurrent exacerbations in severe asthma are associated with enhanced airway closure during stable episodes. Am J Respir Crit Care Med 2000; 161: 1902-1906.
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 1902-1906
    • In't veen, J.C.1    Beekman, A.J.2    Bel, E.H.3    Sterk, P.J.4
  • 6
    • 0032725747 scopus 로고    scopus 로고
    • Anti-inflammatory mechanisms of leukotriene modulators
    • Diamant Z, Sampson AP. Anti-inflammatory mechanisms of leukotriene modulators. Clin Exp Allergy 1999; 29: 1449-1453.
    • (1999) Clin Exp Allergy , vol.29 , pp. 1449-1453
    • Diamant, Z.1    Sampson, A.P.2
  • 8
    • 33749435086 scopus 로고    scopus 로고
    • Improvements in distal lung function correlate with asthma symptoms after treatment with oral montelukast
    • Kraft M, Cairns CB, Ellison MC, Pak J, Irvin C, Wenzel S. Improvements in distal lung function correlate with asthma symptoms after treatment with oral montelukast. Chest 2006; 130; 1726-1732.
    • (2006) Chest , vol.130 , pp. 1726-1732
    • Kraft, M.1    Cairns, C.B.2    Ellison, M.C.3    Pak, J.4    Irvin, C.5    Wenzel, S.6
  • 10
    • 84862862358 scopus 로고    scopus 로고
    • Montelukast as an add-on therapy to inhaled corticosteroids in the treatment of severe asthma in elderly patients
    • Bozek A, Warkocka-Szoltysek B, Filipowska-Gronska A, Jarzab J. Montelukast as an add-on therapy to inhaled corticosteroids in the treatment of severe asthma in elderly patients. J Asthma 2012; 49: 530-534.
    • (2012) J Asthma , vol.49 , pp. 530-534
    • Bozek, A.1    Warkocka-Szoltysek, B.2    Filipowska-Gronska, A.3    Jarzab, J.4
  • 11
    • 0347382609 scopus 로고    scopus 로고
    • Evaluation of airway wall thickness and air trapping by HRCT in asymptomatic asthma
    • Gono H, Fujimoto K, Kawakami S, Kubo K. Evaluation of airway wall thickness and air trapping by HRCT in asymptomatic asthma. Eur Respir J 2003; 22: 965-971.
    • (2003) Eur Respir J , vol.22 , pp. 965-971
    • Gono, H.1    Fujimoto, K.2    Kawakami, S.3    Kubo, K.4
  • 12
    • 21744460847 scopus 로고    scopus 로고
    • Computed tomographic imaging of the airways: Relationship to structure and function
    • de Jong PA, Müller NL, Paré PD, Coxson HO. Computed tomographic imaging of the airways: relationship to structure and function. Eur Respir J 2005; 26: 140-152.
    • (2005) Eur Respir J , vol.26 , pp. 140-152
    • de Jong, P.A.1    Müller, N.L.2    Paré, P.D.3    Coxson, H.O.4
  • 13
    • 58249121587 scopus 로고    scopus 로고
    • A multivariate analysis of risk factors for the air-trapping asthmatic phenotype as measured by quantitative CT analysis
    • Busacker A, Newell Jr JD, Keefe T, Hoffman EA, Granroth JC, Castro M, et al. A multivariate analysis of risk factors for the air-trapping asthmatic phenotype as measured by quantitative CT analysis. Chest 2009; 135: 48-56.
    • (2009) Chest , vol.135 , pp. 48-56
    • Busacker, A.1    Newell, J.D.2    Keefe, T.3    Hoffman, E.A.4    Granroth, J.C.5    Castro, M.6
  • 14
    • 0023445543 scopus 로고
    • Official statement of American Thoracic Society
    • Standardization of spirometry-1987 update
    • Standardization of spirometry-1987 update. Official statement of American Thoracic Society. Respiratory Care 1987; 32: 1039-1060.
    • (1987) Respiratory Care , vol.32 , pp. 1039-1060
  • 15
    • 38949165471 scopus 로고    scopus 로고
    • Lung function in adults with stable but severe asthma: Air trapping and incomplete reversal of obstruction with bronchodilation
    • National Heart, Lung, and Blood Institute Severe Asthma Research Program
    • Sorkness RL, Bleecker ER, Busse WW, Calhoun WJ, Castro M, Chung KF, et al; National Heart, Lung, and Blood Institute Severe Asthma Research Program. Lung function in adults with stable but severe asthma: air trapping and incomplete reversal of obstruction with bronchodilation. J Appl Physiol 2008; 104: 394-403.
    • (2008) J Appl Physiol , vol.104 , pp. 394-403
    • Sorkness, R.L.1    Bleecker, E.R.2    Busse, W.W.3    Calhoun, W.J.4    Castro, M.5    Chung, K.F.6
  • 16
    • 75349101854 scopus 로고    scopus 로고
    • Particle size of inhaled corticosteroids: Does it matter?
    • Leach C, Colice GL, Luskin A. Particle size of inhaled corticosteroids: does it matter? J Allergy Clin Immunol 2009; 124 (6 suppl): 88S-93S.
    • (2009) J Allergy Clin Immunol , vol.124 , Issue.6 SUPPL.
    • Leach, C.1    Colice, G.L.2    Luskin, A.3
  • 17
    • 49649103807 scopus 로고    scopus 로고
    • Targeting small airways in asthma: The new challenge of inhaled corticosteroid treatment
    • Lahzami S, King GG. Targeting small airways in asthma: the new challenge of inhaled corticosteroid treatment. Eur Respir J 2008; 31: 1145-1147.
    • (2008) Eur Respir J , vol.31 , pp. 1145-1147
    • Lahzami, S.1    King, G.G.2
  • 20
    • 0031056743 scopus 로고    scopus 로고
    • Pharmacology of leukotriene receptor antagonists. More than inhibitors of bronchoconstriction
    • Hay DW. Pharmacology of leukotriene receptor antagonists. More than inhibitors of bronchoconstriction. Chest 1997; 111 (2 suppl): 35S-45S.
    • (1997) Chest , vol.111 , Issue.2 SUPPL.
    • Hay, D.W.1
  • 23
    • 0037338743 scopus 로고    scopus 로고
    • Clinical outcomes with montelukast as a partner agent to corticosteroid therapy (COMPACT) international study group. Randomised controlled trial of montelukast plus inhaled budesonide versus double dose inhaled budesonide in adult patients with asthma
    • Price DB, Hernandez D, Magyar P, Fiterman J, Beeh KM, James IG, et al. Clinical outcomes with montelukast as a partner agent to corticosteroid therapy (COMPACT) international study group. Randomised controlled trial of montelukast plus inhaled budesonide versus double dose inhaled budesonide in adult patients with asthma. Thorax 2003; 58: 211-216.
    • (2003) Thorax , vol.58 , pp. 211-216
    • Price, D.B.1    Hernandez, D.2    Magyar, P.3    Fiterman, J.4    Beeh, K.M.5    James, I.G.6
  • 27
    • 0037824477 scopus 로고    scopus 로고
    • Effects of cysteinyl leukotrienes in small human bronchus and antagonist activity of montelukast and its metabolites
    • Mechiche H, Naline E, Candenas L, Pinto FM, Birembault P, Advenier C, et al. Effects of cysteinyl leukotrienes in small human bronchus and antagonist activity of montelukast and its metabolites. Clin Exp Allergy 2003; 33: 887-894.
    • (2003) Clin Exp Allergy , vol.33 , pp. 887-894
    • Mechiche, H.1    Naline, E.2    Candenas, L.3    Pinto, F.M.4    Birembault, P.5    Advenier, C.6
  • 32
    • 33748860064 scopus 로고    scopus 로고
    • Montelukast treatment attenuates the increase in myofibroblasts following low-dose allergen challenge
    • Kelly MM, Chakir J, Vethanayagam D, Boulet LP, Laviolette M, Gauldie J, et al. Montelukast treatment attenuates the increase in myofibroblasts following low-dose allergen challenge. Chest 2006; 130: 741-753.
    • (2006) Chest , vol.130 , pp. 741-753
    • Kelly, M.M.1    Chakir, J.2    Vethanayagam, D.3    Boulet, L.P.4    Laviolette, M.5    Gauldie, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.