Podocyte Expression of Membrane Transporters Involved in Puromycin Aminonucleoside-Mediated Injury

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Zennaro, Cristina ^a   Rastaldi, Maria Pia ^b   Pascolo, Lorella ^e   Stebel, Marco ^a   Trevisan, Elisa ^a   Artero, Mary ^c   Tiribelli, Claudio ^a,d   Di Maso, Vittorio ^a   Carraro, Michele ^a  

^a UNIVERSITY OF TRIESTE   (Italy)

^b FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^c UNIVERSITY HOSPITAL OF TRIESTE   (Italy)

^d Liver Research Center   (Italy)

^e INSTITUTE FOR MATERNAL AND CHILD HEALTH IRCCS BURLO GAROFOLO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; ORGANIC ANION TRANSPORTER 1; ORGANIC ANION TRANSPORTER 2; ORGANIC ANION TRANSPORTER 3; ORGANIC ANION TRANSPORTER 4; PENICILLIN G; PEPTIDE TRANSPORTER 1; PEPTIDE TRANSPORTER 2; PUROMYCIN AMINONUCLEOSIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DAMAGE; CELL MEMBRANE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PODOCYTE; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; RAT;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BIOLOGICAL TRANSPORT; CELL ADHESION; CELL LINE, TUMOR; CELL MEMBRANE PERMEABILITY; CELL PROLIFERATION; CELL SURVIVAL; CYCLOSPORINE; CYTOPROTECTION; GENE EXPRESSION; HUMANS; KIDNEY GLOMERULUS; MALE; ORGANIC ANION TRANSPORTERS; P-GLYCOPROTEIN; PENICILLIN G; PODOCYTES; PUROMYCIN AMINONUCLEOSIDE; RATS; RATS, SPRAGUE-DAWLEY; SERUM ALBUMIN;

EID: 84879268360     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0066159     Document Type: Article

References (25)

1. Tramonti G, Xie P, Wallner EI, Danesh FR, Kanwar YS, (2006) Expression and functional characteristics of tubular transporters: P-glycoprotein, PEPT1, and PEPT2 in renal mass reduction and diabetes. Am J Physiol Renal Physiol 291: F972-F980.
2. Jung SM, Lee WK, Kwak JO, Jung AY, Park J, et al. (2006) Identification of novel murine organic anion transporter like protein 1 (OATLP1) expressed in the kidney. Exp Mol Med 38: 485-493.
3. Lee WK, Hwang JS, Yun CH, Cha SH, (2007) Identification of a kidney-specific mouse organic cation transporter like-1 (mOCTL1). Exp Mol Med 39: 785-795.
4. Gloy J, Reitinger S, Fisher KG, Schreiber R, Boucherot A, et al. (2000) Amino acid transport in podocytes. Am J Physiol Renal Physiol 278: F999-F1005.
5. R Roch Ramel F, De Broe E (2003) Renal handling of drugs and xenobiotics. Clinical nephrotoxins: renal injury from drugs and chemicals. Dordrecht: Kluwer p. 21-46.
6. Xia L, Zhou M, Kalhorn TF, Ho HT, Wang J, (2009) Podocyte-specific expression of organic cation transporter PMAT: implication in puromycin aminonucleoside nephrotoxicity. Am J Physiol Renal Physiol 296: F1307-F1313.
7. Zheng CX, Chen ZH, Zeng CH, Qin WS, Li LS, et al. (2008) Triptolide protects podocytes from puromycin aminonucleoside induced injury in vivo and in vitro. Kidney Int 74: 596-612.
8. Savin VJ, Sharma R, Lovell HV, Welling DJ, (1992) Measurement of albumin reflection coefficient using isolated rat glomeruli. J Am Soc Nephrol 3: 1260-1269.
9. McCarthy ET, Sharma M, Savin VJ, (2010) Circulating permeability factors in idiopathic nephrotic syndrome and focal segmental glomerulosclerosis. Clin J Am Soc Nephrol 5: 2115-2121.
10. Carraro M, Macini W, Artero M, Zennaro C, Faccini L, et al. (2001) Albumin permeability in isolated glomeruli in incipient experimental diabetes mellitus. Diabetologia 12(1): 143-50.
11. Candido R, Carraro M, Fior F, Artelo ML, Zennaro C, et al. (2005) Glomerular permeability defect in hypertension is dependent on renin angiotensin system activation. Am J Hypertens 18(6): 844-50.
12. Carraro M, Zennaro C, Artero M, Candiano G, Ghiggeri GM, et al. (2004) The effect of proteinase inhibitors on glomerular albumin permeability induced in vitro by serum from patients with idiopathic focal segmental glomerulosclerosis. Nephrol Dial Transplant 19(8): 1969-75.
13. Doublier S, Musante L, Lupia E, Candiano G, Spatola T, et al. (2005) Direct effect of plasma permeability factors from patients with idiopathic FSGS on nephrin and podocin expression in human podocytes. Int J Mol Med 16: 49-58.
14. Engel K. Zou M, Wang J, (2004) Identification and characterization of a novel monoamine transporter on the human brain. J.Biol Chem 279: 50042-50049.
15. Chen L, Cheng X, Tian L, Yang T, Hermann S, et al. (2009) Inhibition of P-glycoprotein over-expression by shRNA-mdr1b in rat astrocytes. Neurochem Res 34: 411-417.
16. Diamond JR, Karnovsky MJ, (1986) Focal and segmental glomerulosclerosis following a single intravenous dose of puromycin aminonucleoside. Am J Pathol 122: 481-487.
17. Kim RB, (2003) Organic anion-transporting polypeptide (OATP) transporter family and drug disposition. Eur J Clin Invest 33: 1-5.
18. Kullak-Ublick GA, Ismair MG, Stieger B, Landmann L, Huber R, et al. (2001) Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver. Gastroenterology 120: 525-533.
19. Tamai I, Nezu J, Uchino H, Sai Y, Oku A, et al. (2000) Molecular identification and characterization of novel members of the human organic anion transporters (OATP) family. Biochem Biophys Res Commun 273: 251-260.
20. Vanwert AL, Bailey RM, Sweet DH, (2007) Organic anion transporter 3 (Oat3/Slc22a8) knockout mice exhibit altered clearance and distribution of Penicillin G. Am J Physiol Renal Physiol 293: F1332-F1341.
21. Hsiang B, Zhu Y, Wang Z, Wu Y, Sasseville V, et al. (1999) A novel human hepatic organic anion transporting polypeptide (OATP2). J Biol Chem 274: 37161-37168.
22. Ito A, Yamaguchi K, Tomita H, Suzuki T, Onogawa T, et al. (2003) Distribution of rat organic anion transporting polypeptide-E (Oatp-E) in the rat eye. Invest Ophthalmol Vis Sci 44: 4877-4884.
23. Mikkaichi T, Suzuki T, Onogawa T, Tanemoto M, Mizutamari H, et al. (2004) Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney. Proc Natl Acad Sci USA 101: 3569-3574.
24. del Moral RG, Olmo A, Aguillar M, O'Valle F, (1998) P-glycoprotein: a new mechanism to control drug-induced nephrotoxicity. Exp Nephrol 6: 89-97.
25. Bello-Reuss E, Ernest S (1994) Expression and function of P-glycoprotein in human mesangial cells. Am J Physiol 267(5 Pt 1) C1351-C1358.