-
2
-
-
84865332134
-
Modeling tumor growth in oncology
-
P.L. Bonate, D.R. Howard, American Association of Pharmaceutical Scientists, LLC
-
P.L. Bonate Modeling tumor growth in oncology P.L. Bonate, D.R. Howard, Pharmacokinetics in Drug Development 2011 American Association of Pharmaceutical Scientists, LLC
-
(2011)
Pharmacokinetics in Drug Development
-
-
Bonate, P.L.1
-
3
-
-
84880922536
-
PKPD and disease modeling: Concepts and applications to oncology
-
H.H.C. Kimko, C.C. Peck, AAPS Advances in the Pharmaceutical Sciences Series 1, Springer Science + Business Media, LLC
-
O.E. Della Pasqua PKPD and disease modeling: concepts and applications to oncology H.H.C. Kimko, C.C. Peck, Clinical Trial Simulations 2011 AAPS Advances in the Pharmaceutical Sciences Series 1, Springer Science + Business Media, LLC
-
(2011)
Clinical Trial Simulations
-
-
Della Pasqua, O.E.1
-
4
-
-
81855217734
-
Chemotherapy investigations in cancer; With reference to the influence of certain organic dibasic acids, diamino compounds and nitro compounds on tumors in mice
-
D.L. Woodhouse Chemotherapy investigations in cancer; with reference to the influence of certain organic dibasic acids, diamino compounds and nitro compounds on tumors in mice Cancer Res. 7 1947 398 401
-
(1947)
Cancer Res.
, vol.7
, pp. 398-401
-
-
Woodhouse, D.L.1
-
5
-
-
0024117741
-
Human tumor xenografts as model for drug testing
-
J. Mattern Human tumor xenografts as model for drug testing Cancer Metastasis Rev. 7 1988 263 284
-
(1988)
Cancer Metastasis Rev.
, vol.7
, pp. 263-284
-
-
Mattern, J.1
-
6
-
-
0014649888
-
Heterotransplantation of a human malignant tumour to the mouse mutant 'nude'
-
J. Rygaard Heterotransplantation of a human malignant tumour to the mouse mutant 'nude' Acta Pathol. Microbiol. Scand. 77 1969 758 760
-
(1969)
Acta Pathol. Microbiol. Scand.
, vol.77
, pp. 758-760
-
-
Rygaard, J.1
-
7
-
-
0030014198
-
Experimental antitumor activity and pharmacokinetics of camptothecin analog irinotecan (CPT-11) in mice
-
M.C. Bissery Experimental antitumor activity and pharmacokinetics of camptothecin analog irinotecan (CPT-11) in mice Anticancer Drugs 7 1996 437 460
-
(1996)
Anticancer Drugs
, vol.7
, pp. 437-460
-
-
Bissery, M.C.1
-
8
-
-
55749094502
-
Antitumor efficacy testing in rodents
-
M.G. Hollingshead Antitumor efficacy testing in rodents J. Natl. Cancer Inst. 100 2008 1500 1510
-
(2008)
J. Natl. Cancer Inst.
, vol.100
, pp. 1500-1510
-
-
Hollingshead, M.G.1
-
9
-
-
1942422743
-
Of mice and men: Values and liabilities of the athymic nude mouse model in anticancer drug development
-
L.R. Kelland Of mice and men: values and liabilities of the athymic nude mouse model in anticancer drug development Eur. J. Cancer 40 2004 827 836
-
(2004)
Eur. J. Cancer
, vol.40
, pp. 827-836
-
-
Kelland, L.R.1
-
10
-
-
77954637445
-
Genetically engineered mouse models in cancer research
-
J.C. Walrath Genetically engineered mouse models in cancer research Adv. Cancer Res. 106 2010 113 164
-
(2010)
Adv. Cancer Res.
, vol.106
, pp. 113-164
-
-
Walrath, J.C.1
-
11
-
-
15244351351
-
Pharmacokinetic-pharmacodynamic model for predicting tumour growth inhibition in mice: A useful tool in oncology drug development
-
M. Rocchetti Pharmacokinetic-pharmacodynamic model for predicting tumour growth inhibition in mice: a useful tool in oncology drug development Basic Clin. Pharmacol. Toxicol. 2005 265 268
-
(2005)
Basic Clin. Pharmacol. Toxicol.
, pp. 265-268
-
-
Rocchetti, M.1
-
12
-
-
0141566685
-
Clinical predictive value of the in vitro cell line, human xenograft, and mouse allograft preclinical cancer models
-
T. Voskoglou-Nomikos Clinical predictive value of the in vitro cell line, human xenograft, and mouse allograft preclinical cancer models Clin. Cancer Res. 9 2003 4227 4239
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 4227-4239
-
-
Voskoglou-Nomikos, T.1
-
14
-
-
84966166281
-
Dynamics of tumor growth
-
A.K. Laird Dynamics of tumor growth Br. J. Cancer 18 1964 490 502
-
(1964)
Br. J. Cancer
, vol.18
, pp. 490-502
-
-
Laird, A.K.1
-
15
-
-
0014794416
-
Kinetic parameter and growth curves for experimental tumor systems
-
Simpson-Herren, and Lloyd Kinetic parameter and growth curves for experimental tumor systems Cancer Chemotherapy Rep. 54 1970 143 174
-
(1970)
Cancer Chemotherapy Rep.
, vol.54
, pp. 143-174
-
-
Simpson-Herren1
Lloyd2
-
16
-
-
0015367243
-
Kinetics of tumor growth and regression in IgG multiple myeloma
-
P.W. Sullivan, and S.E. Salmon Kinetics of tumor growth and regression in IgG multiple myeloma J. Clin. Invest. 51 1972 1697 1708
-
(1972)
J. Clin. Invest.
, vol.51
, pp. 1697-1708
-
-
Sullivan, P.W.1
Salmon, S.E.2
-
17
-
-
0017200032
-
Predicting the course of Gompertzian growth
-
L. Norton Predicting the course of Gompertzian growth Nature (Lond.) 264 1976 542 545
-
(1976)
Nature (Lond.)
, vol.264
, pp. 542-545
-
-
Norton, L.1
-
18
-
-
0017736818
-
Growth curve of an experimental solid tumor following radiotherapy
-
L. Norton, and R. Simon Growth curve of an experimental solid tumor following radiotherapy J. Natl. Cancer Inst. (Bethesda) 58 1977 1735 1741
-
(1977)
J. Natl. Cancer Inst. (Bethesda)
, vol.58
, pp. 1735-1741
-
-
Norton, L.1
Simon, R.2
-
19
-
-
33747007990
-
The Norton-Simon hypothesis: Designing more effective and less toxic chemotherapeutic regimens
-
R. Simon, and L. Norton The Norton-Simon hypothesis: designing more effective and less toxic chemotherapeutic regimens Nat. Clin. Pract. Oncol. 3 2006 406 407
-
(2006)
Nat. Clin. Pract. Oncol.
, vol.3
, pp. 406-407
-
-
Simon, R.1
Norton, L.2
-
20
-
-
0842282616
-
Predictive pharmacokinetic-pharmacodynamic modeling of tumor growth kinetics in xenograft models after administration of anticancer agents
-
M. Simeoni Predictive pharmacokinetic-pharmacodynamic modeling of tumor growth kinetics in xenograft models after administration of anticancer agents Cancer Res. 64 2004 1094 1101
-
(2004)
Cancer Res.
, vol.64
, pp. 1094-1101
-
-
Simeoni, M.1
-
21
-
-
33646040109
-
A mathematical model to study the effects of drug administration on tumor growth dynamics
-
P. Magni A mathematical model to study the effects of drug administration on tumor growth dynamics Math. Biosci. 200 2006 127 151
-
(2006)
Math. Biosci.
, vol.200
, pp. 127-151
-
-
Magni, P.1
-
22
-
-
85046916618
-
Pharmacodynamic modeling of chemotherapeutic effects: Application of a transit compartment model to characterize methotrexate effects in vitro
-
E.D. Lobo, and J.P. Balthasar Pharmacodynamic modeling of chemotherapeutic effects: application of a transit compartment model to characterize methotrexate effects in vitro AAPS PharmSci. 4 2002 E42
-
(2002)
AAPS PharmSci.
, vol.4
, pp. 42
-
-
Lobo, E.D.1
Balthasar, J.P.2
-
23
-
-
77449096899
-
Comparison of two pharmacodynamic transduction models for the analysis of tumor therapeutic responses in model systems
-
J. Yang Comparison of two pharmacodynamic transduction models for the analysis of tumor therapeutic responses in model systems AAPS J. 12 2010 1 10
-
(2010)
AAPS J.
, vol.12
, pp. 1-10
-
-
Yang, J.1
-
24
-
-
58149250388
-
A minimal model of tumor growth inhibition
-
P. Magni A minimal model of tumor growth inhibition IEEE Trans. Biomed. Eng. 55 2008 2683 2690
-
(2008)
IEEE Trans. Biomed. Eng.
, vol.55
, pp. 2683-2690
-
-
Magni, P.1
-
25
-
-
77956759089
-
Modeling the efficacy of trastuzumab-DM1, an antibody drug conjugate, in mice
-
N.L. Jumbe Modeling the efficacy of trastuzumab-DM1, an antibody drug conjugate, in mice J. Pharmacokinet. Pharmacodyn. 37 2010 221 242
-
(2010)
J. Pharmacokinet. Pharmacodyn.
, vol.37
, pp. 221-242
-
-
Jumbe, N.L.1
-
26
-
-
65949084712
-
A combined pharmacokinetic-pharmacodynamic (PK-PD) model for tumor growth in the rat with UFT administration
-
J.H. Sung A combined pharmacokinetic-pharmacodynamic (PK-PD) model for tumor growth in the rat with UFT administration J. Pharm. Sci. 98 2009 1885 1904
-
(2009)
J. Pharm. Sci.
, vol.98
, pp. 1885-1904
-
-
Sung, J.H.1
-
27
-
-
77953057864
-
Preclinical pharmacokinetic/pharmacodynamic models to predict synergistic effects of co-administered anti-cancer agents
-
K. Goteti Preclinical pharmacokinetic/pharmacodynamic models to predict synergistic effects of co-administered anti-cancer agents J. Cancer Chemother. Pharmacol. 66 2010 245 254
-
(2010)
J. Cancer Chemother. Pharmacol.
, vol.66
, pp. 245-254
-
-
Goteti, K.1
-
28
-
-
67349159357
-
Modeling of tumor growth and anticancer effects of combination therapy
-
G. Koch Modeling of tumor growth and anticancer effects of combination therapy J. Pharmacokinet. Pharmacodyn. 36 2009 179 197
-
(2009)
J. Pharmacokinet. Pharmacodyn.
, vol.36
, pp. 179-197
-
-
Koch, G.1
-
29
-
-
70450250213
-
Testing additivity of anticancer agents in pre-clinical studies: A PK/PD modelling approach
-
M. Rocchetti Testing additivity of anticancer agents in pre-clinical studies: a PK/PD modelling approach Eur. J. Cancer 45 2009 3336 3346
-
(2009)
Eur. J. Cancer
, vol.45
, pp. 3336-3346
-
-
Rocchetti, M.1
-
30
-
-
37149042061
-
Semi-mechanistic modelling of the tumour growth inhibitory effects of LY2157299, a new type i receptor TGF-beta kinase antagonist, in mice
-
L. Bueno Semi-mechanistic modelling of the tumour growth inhibitory effects of LY2157299, a new type I receptor TGF-beta kinase antagonist, in mice Eur. J. Cancer 44 2008 142 150
-
(2008)
Eur. J. Cancer
, vol.44
, pp. 142-150
-
-
Bueno, L.1
-
31
-
-
46449090520
-
Pharmacokinetic-pharmacodynamic modeling of biomarker response and tumor growth inhibition to an orally available cMet kinase inhibitor in human tumor xenograft mouse models
-
S. Yamazaki Pharmacokinetic-pharmacodynamic modeling of biomarker response and tumor growth inhibition to an orally available cMet kinase inhibitor in human tumor xenograft mouse models Drug Met. Disp. 36 2008 1267 1274
-
(2008)
Drug Met. Disp.
, vol.36
, pp. 1267-1274
-
-
Yamazaki, S.1
-
32
-
-
77955986074
-
Pharmacokinetic-pharmacodynamic modeling of tumor growth inhibition and biomarker modulation by the novel phosphatidylinositol 3-kinase inhibitor GDC-0941
-
L. Salphati Pharmacokinetic-pharmacodynamic modeling of tumor growth inhibition and biomarker modulation by the novel phosphatidylinositol 3-kinase inhibitor GDC-0941 Drug Met. Disp. 38 2010 1436 1442
-
(2010)
Drug Met. Disp.
, vol.38
, pp. 1436-1442
-
-
Salphati, L.1
-
33
-
-
0028844579
-
Design and analysis of in vitro antitumor pharmacodynamic studies
-
J.E. Kalns Design and analysis of in vitro antitumor pharmacodynamic studies Cancer Res. 55 1995 5315 5322
-
(1995)
Cancer Res.
, vol.55
, pp. 5315-5322
-
-
Kalns, J.E.1
-
34
-
-
0034100027
-
A pharmacodynamic analysis method to determine the relative importance of drug concentration and treatment time on effect
-
N.J. Millenbaugh A pharmacodynamic analysis method to determine the relative importance of drug concentration and treatment time on effect Cancer Chemother. Pharmacol. 45 2000 265 272
-
(2000)
Cancer Chemother. Pharmacol.
, vol.45
, pp. 265-272
-
-
Millenbaugh, N.J.1
-
35
-
-
0344944187
-
In vitro cell growth pharmacodynamic studies: A new nonparametric approach to determining the relative importance of drug concentration and treatment time
-
M. Germani In vitro cell growth pharmacodynamic studies: a new nonparametric approach to determining the relative importance of drug concentration and treatment time Cancer Chemother. Pharmacol. 52 2003 Dec 507 513
-
(2003)
Cancer Chemother. Pharmacol.
, vol.52
, pp. 507-513
-
-
Germani, M.1
-
36
-
-
61449114851
-
A model-based approach to the in vitro evaluation of anticancer activity
-
F. Del Bene A model-based approach to the in vitro evaluation of anticancer activity Cancer Chemother. Pharmacol. 63 2009 827 836
-
(2009)
Cancer Chemother. Pharmacol.
, vol.63
, pp. 827-836
-
-
Del Bene, F.1
-
37
-
-
34249980052
-
Mathematical models of avascular tumor growth
-
T. Roose Mathematical models of avascular tumor growth SIAM Rev. 49 2008 179 208
-
(2008)
SIAM Rev.
, vol.49
, pp. 179-208
-
-
Roose, T.1
-
38
-
-
76149128357
-
Nonlinear modelling of cancer: Bridging the gap between cells and tumours
-
J.S. Lowengrub Nonlinear modelling of cancer: bridging the gap between cells and tumours Nonlinearity 23 2010 R1 R91
-
(2010)
Nonlinearity
, vol.23
-
-
Lowengrub, J.S.1
-
39
-
-
77649126707
-
Dissecting cancer through mathematics: From the cell to the animal model
-
H.M. Byrne Dissecting cancer through mathematics: from the cell to the animal model Nat. Rev. Cancer 10 2010 221 230
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 221-230
-
-
Byrne, H.M.1
-
40
-
-
0842348242
-
Mathematical modelling of the use of macrophages as vehicles for drug delivery to hypoxic tumour sites
-
M.R. Owen Mathematical modelling of the use of macrophages as vehicles for drug delivery to hypoxic tumour sites J. Theor. Biol. 226 2004 377 391
-
(2004)
J. Theor. Biol.
, vol.226
, pp. 377-391
-
-
Owen, M.R.1
-
41
-
-
28444483647
-
A multiscale model for avascular tumor growth
-
Erratum in: Biophys J. 91(2): 775
-
Y. Jiang A multiscale model for avascular tumor growth Biophys. J. 89 2005 3884 3894 Erratum in: Biophys J. 91(2): 775
-
(2005)
Biophys. J.
, vol.89
, pp. 3884-3894
-
-
Jiang, Y.1
-
42
-
-
33751226638
-
A multiscale mathematical model of avascular tumor growth to investigate the therapeutic benefit of anti-invasive agents
-
B. Ribba A multiscale mathematical model of avascular tumor growth to investigate the therapeutic benefit of anti-invasive agents J. Theor. Biol. 243 2006 532 541
-
(2006)
J. Theor. Biol.
, vol.243
, pp. 532-541
-
-
Ribba, B.1
-
43
-
-
33646249607
-
A multiscale mathematical model of cancer, and its use in analyzing irradiation therapies
-
B. Ribba A multiscale mathematical model of cancer, and its use in analyzing irradiation therapies J. Theor. Biol. 3 2006 7
-
(2006)
J. Theor. Biol.
, vol.3
, pp. 7
-
-
Ribba, B.1
-
44
-
-
0002833130
-
Conceptual frameworks for mathematical modeling of tumor growth dynamics
-
Z. Bajzer Conceptual frameworks for mathematical modeling of tumor growth dynamics Math. Comput. Model. 23 1996 31 46
-
(1996)
Math. Comput. Model.
, vol.23
, pp. 31-46
-
-
Bajzer, Z.1
-
45
-
-
0034254401
-
Modeling and mathematical problems related to tumor evolution and its interaction with the immune system
-
N. Bellomo, and L. Preziosi Modeling and mathematical problems related to tumor evolution and its interaction with the immune system Math. Comput. Model. 32 2000 m413 m452
-
(2000)
Math. Comput. Model.
, vol.32
-
-
Bellomo, N.1
Preziosi, L.2
-
46
-
-
34250758632
-
A Generalised age- and phase-structured model of human tumour cell populations both unperturbed and exposed to a range of cancer therapies
-
B. Basse, and P. Ubezio A Generalised age- and phase-structured model of human tumour cell populations both unperturbed and exposed to a range of cancer therapies Bull. Math. Biol. 69 2007 1673 1690
-
(2007)
Bull. Math. Biol.
, vol.69
, pp. 1673-1690
-
-
Basse, B.1
Ubezio, P.2
-
47
-
-
40149101292
-
Simulating non-small cell lung cancer with a multiscale agent-based model
-
Z. Wang Simulating non-small cell lung cancer with a multiscale agent-based model Theor. Biol. Med. Model. 4 2007 50
-
(2007)
Theor. Biol. Med. Model.
, vol.4
, pp. 50
-
-
Wang, Z.1
-
48
-
-
58349094920
-
Multiscale agent-based cancer modeling
-
L. Zhang Multiscale agent-based cancer modeling J. Math. Biol. 58 2009 545 559
-
(2009)
J. Math. Biol.
, vol.58
, pp. 545-559
-
-
Zhang, L.1
-
49
-
-
79251593424
-
A model of vascular tumour growth in mice combining longitudinal tumour size data with histological biomarkers
-
B. Ribba A model of vascular tumour growth in mice combining longitudinal tumour size data with histological biomarkers Eur. J. Cancer 47 2011 479 490
-
(2011)
Eur. J. Cancer
, vol.47
, pp. 479-490
-
-
Ribba, B.1
-
50
-
-
0017688679
-
Estimation of population characteristics of pharmacokinetic parameters from routine clinical data
-
L.B. Sheiner Estimation of population characteristics of pharmacokinetic parameters from routine clinical data J. Pharmacokin. Pharmacodyn. 5 1977 445 479
-
(1977)
J. Pharmacokin. Pharmacodyn.
, vol.5
, pp. 445-479
-
-
Sheiner, L.B.1
-
51
-
-
84879218147
-
Population modeling of tumor growth in untreated xenografted mice
-
Uppsala PAGE 13, Abstr 535
-
Poggesi, I. et al. (2004). Population modeling of tumor growth in untreated xenografted mice. Abstracts of the Annual Meeting of the Population Approach Group in Europe, Uppsala PAGE 13, Abstr 535 [ http://www.page-meeting. org/?abstract=535 ]
-
(2004)
Abstracts of the Annual Meeting of the Population Approach Group in Europe
-
-
Poggesi, I.1
-
52
-
-
84879202108
-
Population modeling of tumor growth inhibition in vivo: Application to anticancer drug development
-
Uppsala PAGE 13, PAGE 13 (2004) Abstr 503
-
Simeoni, M. et al. Population modeling of tumor growth inhibition in vivo: application to anticancer drug development. Abstracts of the Annual Meeting of the Population Approach Group in Europe, Uppsala PAGE 13, PAGE 13 (2004) Abstr 503 [ http://www.page-meeting.org/?abstract=503 ]
-
Abstracts of the Annual Meeting of the Population Approach Group in Europe
-
-
Simeoni, M.1
-
53
-
-
0141973782
-
The phase III trial in the era of targeted therapy: Unraveling the go and no go decision
-
T.G. Roberts The phase III trial in the era of targeted therapy: unraveling the go and no go decision J. Clin. Oncol. 19 2003 3683 3695
-
(2003)
J. Clin. Oncol.
, vol.19
, pp. 3683-3695
-
-
Roberts, T.G.1
-
54
-
-
72949093415
-
Antitumor efficacytesting in rodents
-
I. Poggesi Antitumor efficacytesting in rodents J. Natl. Cancer Inst. 101 2009 1592 1593
-
(2009)
J. Natl. Cancer Inst.
, vol.101
, pp. 1592-1593
-
-
Poggesi, I.1
-
55
-
-
34547842118
-
Predicting the active doses in humans from animal studies: A novel approach in oncology
-
M. Rocchetti Predicting the active doses in humans from animal studies: a novel approach in oncology Eur. J. Cancer 12 2007 1862 1868
-
(2007)
Eur. J. Cancer
, vol.12
, pp. 1862-1868
-
-
Rocchetti, M.1
-
56
-
-
77649115839
-
Benefit-risk assessment: The use of clinical utility index
-
D. Ouellet Benefit-risk assessment: the use of clinical utility index Expert Opin. Drug Safety 9 2010 289 300
-
(2010)
Expert Opin. Drug Safety
, vol.9
, pp. 289-300
-
-
Ouellet, D.1
-
57
-
-
2442710541
-
Clinical relevance of different sequencing of doxorubicin and cyclophosphamide, methotrexate and fluorouracil in operable breast cancer
-
G. Bonadonna Clinical relevance of different sequencing of doxorubicin and cyclophosphamide, methotrexate and fluorouracil in operable breast cancer J. Clin. Oncol. 22 2004 1614 1620
-
(2004)
J. Clin. Oncol.
, vol.22
, pp. 1614-1620
-
-
Bonadonna, G.1
-
58
-
-
0037687355
-
Randomized trial of dose-dense versus conventionally scheduled and sequential versus concurrent combination chemotherapy as postoperative adjuvant treatment of node-positive primary breast cancer: First report of Intergroup trial C9741/Cancer and Leukemia Group B trial 9741
-
M.L. Citron Randomized trial of dose-dense versus conventionally scheduled and sequential versus concurrent combination chemotherapy as postoperative adjuvant treatment of node-positive primary breast cancer: first report of Intergroup trial C9741/Cancer and Leukemia Group B trial 9741 J. Clin. Oncol. 21 2003 1431 1439
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 1431-1439
-
-
Citron, M.L.1
-
59
-
-
67651171223
-
Elucidation of relationship between tumor size and survival in non-small-cell lung cancer patients can aid early decision making in clinical drug development
-
Y. Wang Elucidation of relationship between tumor size and survival in non-small-cell lung cancer patients can aid early decision making in clinical drug development Clin. Pharmacol. Ther. 86 2009 167 174
-
(2009)
Clin. Pharmacol. Ther.
, vol.86
, pp. 167-174
-
-
Wang, Y.1
-
60
-
-
70249134646
-
Model-based prediction of phase III overall survival in colorectal cancer on the basis of phase II tumor dynamics
-
L. Claret Model-based prediction of phase III overall survival in colorectal cancer on the basis of phase II tumor dynamics J. Clin. Oncol. 27 2009 4103 4108
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 4103-4108
-
-
Claret, L.1
-
61
-
-
34249305482
-
Modeling biomarker dynamics with implications for the treatment of prostate cancer
-
E.B. Hedican Modeling biomarker dynamics with implications for the treatment of prostate cancer Comput. Math. Methods Med. 8 2007 77 92
-
(2007)
Comput. Math. Methods Med.
, vol.8
, pp. 77-92
-
-
Hedican, E.B.1
-
62
-
-
65549156693
-
Concepts and challenges in quantitative pharmacology and model-based drug development
-
L. Zhang Concepts and challenges in quantitative pharmacology and model-based drug development AAPS J. 10 2008 552 559
-
(2008)
AAPS J.
, vol.10
, pp. 552-559
-
-
Zhang, L.1
-
63
-
-
84879249595
-
International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH)
-
March 2010
-
International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). S9 Nonclinical Evaluation for Anticancer Pharmaceuticals; March 2010
-
S9 Nonclinical Evaluation for Anticancer Pharmaceuticals
-
-
-
64
-
-
84857996192
-
New regulatory framework for cancer drug development
-
P.S. Jones, and D. Jones New regulatory framework for cancer drug development Drug Discov. Today 17 2012 227 231
-
(2012)
Drug Discov. Today
, vol.17
, pp. 227-231
-
-
Jones, P.S.1
Jones, D.2
-
67
-
-
84879226123
-
-
European Medicines Agency-European Federation of Pharmaceutical Industries and Associations modelling and simulation workshop; 30/11/2011-01/12/2011, London (UK)
-
European Medicines Agency-European Federation of Pharmaceutical Industries and Associations modelling and simulation workshop; 30/11/2011-01/12/2011, London (UK); http://www.ema.europa.eu/ema/index.jsp?curl= pages/news-and-events/events/2011/07/event-detail-000440.jsp&mid= WC0b01ac058004d5c3
-
-
-
-
68
-
-
79957618123
-
New pathway for qualification of novel methodologies in the European Medicines Agency
-
E.E. Manolis New pathway for qualification of novel methodologies in the European Medicines Agency Proteomics Clin. Appl. 5 2011 248 255
-
(2011)
Proteomics Clin. Appl.
, vol.5
, pp. 248-255
-
-
Manolis, E.E.1
-
69
-
-
34250749661
-
Model-based drug development
-
R.L. Lalonde Model-based drug development Clin. Pharmacol. Ther. 82 2007 21 32
-
(2007)
Clin. Pharmacol. Ther.
, vol.82
, pp. 21-32
-
-
Lalonde, R.L.1
|