In vitro cell growth pharmacodynamic studies: A new nonparametric approach to determining the relative importance of drug concentration and treatment time

Cancer Chemotherapy and Pharmacology

Volumn 52, Issue 6, 2003, Pages 507-513

  Germani, Massimiliano ^a   Magni, Paolo ^b   De Nicolao, Giuseppe ^b   Poggesi, Italo ^a   Marsiglio, Aurelio ^c   Ballinari, Dario ^c   Rocchetti, Maurizio ^a  

^a Global Drug Metabolism Department   (Italy)

^b UNIVERSITY OF PAVIA   (Italy)

^c Discovery Research Oncology   (Italy)

Author keywords

Cell based in vitro testing; Neural networks; Pharmacodynamic analysis; Response surface

Indexed keywords

DOXORUBICIN; FLAVOPIRIDOL;

ALGORITHM; ARTICLE; CANCER CHEMOTHERAPY; CANCER GROWTH; CANCER INHIBITION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFECT; DRUG EXPOSURE; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MEDICAL LITERATURE; NERVE CELL NETWORK; PHARMACODYNAMICS; PRIORITY JOURNAL; THEORY; TREATMENT OUTCOME;

ANTINEOPLASTIC AGENTS; CELL DIVISION; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; FLAVONOIDS; HUMANS; NEURAL NETWORKS (COMPUTER); PIPERIDINES; TIME FACTORS;

EID: 0344944187     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-003-0688-7     Document Type: Article

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