Genetic clonal mapping of in situ and invasive ductal carcinoma indicates the field cancerization phenomenon in the breast

Human Pathology

Volumn 44, Issue 7, 2013, Pages 1310-1319

  Foschini, Maria P ^a   Morandi, Luca ^a   Leonardi, Elisa ^a   Flamminio, Federica ^a   Ishikawa, Yuko ^a   Masetti, Riccardo ^b   Eusebi, Vincenzo ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b CATHOLIC UNIVERSITY   (Italy)

Author keywords

Breast; Clonality; Field cancerization; In situ duct carcinoma; Invasive duct carcinoma

Indexed keywords

MITOCHONDRIAL DNA;

ADULT; AGED; ARTICLE; BREAST CARCINOMA; CANCER CELL; CANCER PATIENT; CARCINOMA IN SITU; CLINICAL ARTICLE; CLONAL VARIATION; CONTROLLED STUDY; FEMALE; GENE MAPPING; GENETIC DISTANCE; HUMAN; HUMAN TISSUE; INTRADUCTAL CARCINOMA; LYMPH NODE METASTASIS; NEIGHBOR JOINING METHOD; PHYLOGENY; POINT MUTATION; RANDOMIZED CONTROLLED TRIAL; TISSUE SECTION;

ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CARCINOMA, INTRADUCTAL, NONINFILTRATING; CELL TRANSFORMATION, NEOPLASTIC; CLONE CELLS; DISEASE PROGRESSION; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MIDDLE AGED; PRECANCEROUS CONDITIONS;

EID: 84879236552     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2012.09.022     Document Type: Article

References (37)

1. M.P. Foschini, T. Tot, and V. Eusebi Large-section (macrosection) histologic slides M.J. Silverstein, Ductal carcinoma in situ of the breast 2nd ed. 2002 Lippincott Philadelphia 249 254
2. T. Tot, and L. Tabar The role of radiological-pathological correlation in diagnosing early breast cancer: the pathologist's perspective Virchows Arch 458 2011 125 131
3. M.P. Foschini, F. Flamminio, and R. Miglio The impact of large sections on the study of in situ and invasive duct carcinoma of the breast Hum Pathol 38 2007 1736 1743
4. L. Morandi, G. Marucci, and M.P. Foschini Genetic similarities and differences between lobular in situ neoplasia (LN) and invasive lobular carcinoma of the breast Virchows Arch 449 2006 14 23
5. J.J. Going, and D.F. Moffat Escaping from flatland: clinical and biological aspects of human mammary duct anatomy in three dimensions J Pathol 203 2004 538 544
6. T. Tot DCIS, cytokeratins, and the theory of the sick lobe Virchows Arch 447 2005 1 8
7. S.R. Wellings, and H.M. Jensen On the origin and progression of ductal carcinoma in the human breast J Natl Cancer Inst 50 1973 1111 1118
8. T. Tot The diffuse type of invasive lobular carcinoma of the breast: morphology and prognosis Virchows Arch 443 2003 718 724
9. M.P. Foschini, A. Righi, and M.C. Cucchi The impact of large sections and 3D technique on the study of lobular in situ and invasive carcinoma of the breast Virchows Arch 448 2006 256 261
10. T. Tot, M. Gere, and G. Pekar Breast cancer multifocality, disease extent, and survival Hum Pathol 42 2011 1761 1769
11. S.R. Lakhani, I.O. Ellis, S.J. Schnitt, P.H. Tan, and M.J. Van De Vijver WHO Classification of Tumours of the Breast 4th ed. 2012 IARC Press Lyon
12. D.L. Page, L.W. Rogers, P.A. Schuyler, W.D. Dupont, and R.A. Jensen The natural history of ductal carcinoma in situ of the breast M.J. Silverstein, Ductal carcinoma in situ of the breast 2nd ed. 2002 Lippincott Philadelphia 17 21
13. M. Kimura A simple method for estimating evolutionary rate of base substitution through comparative studies of nucleotide sequences J Mol Evol 16 1980 111 116
14. F.A. Tavassoli, and V. Eusebi Tumors of the breast 4 ed. 2009 American Registry of Pathology/AFIP Washington, DC
15. C.W. Elston, and I.O. Ellis Pathological prognostic factors in breast cancer. 1. The value of histological grade in breast cancer: experience from a large study with long-term follow-up Histopathology 19 1991 403 410
16. T. Tot Clinical relevance of the distribution of the lesions in 500 consecutive breast cancer cases documented in large format histologic sections Cancer 110 2007 2551 2560
17. S. Anderson, A.T. Bankier, and B.G. Barrel Sequence and organization of the human mitochondrial genome Nature 290 1981 457 465
18. MITOWEB MITOMAP: A Human Mitochondrial Genome Database http://www.mitomap.org/MITOMAP Published 2012. Accessed 2012 May 10
19. S. Rozen, and H.J. Skaletsky Primer3 on the WWW for general users and for biologist programmers S. Krawetz, S. Misener, Bioinformatics Methods and Protocols: Methods in Molecular Biology 2000 Humana Press Totowa, NJ 365 386 http://sourceforge.net/projects/primer3/
20. M. Woischnik, and C.T. Moraes Pattern of organization of human mitochondrial pseudogenes in the nuclear genome Genome Res 12 2002 885 893
21. S. Kumar, and S.R. Gadagkar Efficiency of the neighbor-joining method in reconstructing deep and shallow evolutionary relationships in large phylogenies J Mol Evol 51 2000 544 553
22. N. Saitou, and M. Nei The neighbor joining method: a new method to reconstructing phylogenetic trees Mol Biol Evol 4 1987 406 425
23. K. Tamura, J. Dudley, M. Nei, and S. Kumar MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0 Mol Biol Evol 24 2007 1596 1599
24. L. Morandi, S. Asioli, A. Cavazza, A. Pession, and S. Damiani Genetic relationship among atypical adenomatous hyperplasia, bronchioloalveolar carcinoma and adenocarcinoma of the lung Lung Cancer 56 2007 35 42
25. M.P. Foschini, L. Morandi, and C. Marchetti Cancerization of cutaneous flap reconstruction for oral squamous cell carcinoma: report of three cases studied with the mtDNA D-loop sequence analysis Histopathology 58 2011 361 367
26. L. Morandi, A. Pession, and G. Marucci Intraepidermal cells of Paget's carcinoma of the breast can be genetically different from those of the underlying carcinoma Hum Pathol 34 2003 1321 1330
27. L. Carrel, and H.F. Willard X-inactivation profile reveals extensive variability in X-linked gene expression in females Nature 434 2005 400 404
28. J.J. Salk, and M.S. Horwitz Passenger mutations as a marker of clonal cell lineages in emerging neoplasia Semin Cancer Biol 20 2010 294 303
29. S.I. Pai, and W.H. Westra Molecular pathology of head and neck cancer: implications for diagnosis, prognosis, and treatment Ann Rev Pathol 4 2009 49 70
30. A.M. Dworkin, T.H. Huang, and A.E. Toland Epigenetic alterations in the breast: implications for breast cancer detection, prognosis and treatment Semin Cancer Biol 19 2009 165 171
31. D.P. Slaughter, H.W. Southwick, and W. Smeejkal Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin Cancer 6 1953 963 968
32. P.K. Ha, and J.A. Califano The molecular biology of mucosal field cancerization of the head and neck Crit Rev Oral Biol Med 14 2003 363 369
33. R. Hitt, and M.J. Echarri Molecular biology in head and neck cancer Clin Transl Oncol 8 2006 776 779
34. C.R. Leemans, B.J. Braakhuis, and R.H. Brakenhoff The molecular biology of head and neck cancer Nat Rev Cancer 11 2011 9 22
35. M. Volante, A. Sapino, S. Croce, and G. Bussolati Heterogeneous versus homogeneous genetic nature of multiple foci of in situ carcinoma of the breast Hum Pathol 34 2003 1163 1169
36. S. Aulmann, R. Penzel, T. Longerich, B. Funke, P. Schirmacher, and H.P. Sinn Clonality of lobular carcinoma in situ (LCIS) and metachronous invasive breast cancer Breast Cancer Res Treat 107 2008 331 335
37. C.M. Heaphy, J.K. Griffith, and M. Bisoffi Mammary field cancerization: molecular evidence and clinical importance Breast Cancer Res Treat 118 2009 229 239