The co-effect of Cordyceps sinensis and strontium on osteoporosis in ovariectomized osteopenic rats

Biological Trace Element Research

Volumn 141, Issue 1-3, 2011, Pages 216-223

  Qi, Wei ^a,b   Yan, Ya Bo ^a   Wang, Pu Jie ^b   Lei, Wei ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b 520th Hospital of PLA   (China)

Author keywords

Calcium; Cordyceps sinensis (caterpillar fungus); Inorganic phosphate; Osteoporosis; Strontium

Indexed keywords

CALCIUM; ESTRADIOL; PHOSPHORUS; STRONTIUM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY MASS; BONE MINERAL; BONE STRENGTH; CALCIUM BLOOD LEVEL; CALCIUM URINE LEVEL; FEMALE; FEMUR NECK; IMMUNOMODULATION; NONHUMAN; OPHIOCORDYCEPS; OSTEOPOROSIS; OVARIECTOMY; PHOSPHATE BLOOD LEVEL; RAT; THYMUS; URINARY EXCRETION; UTERUS;

ANIMALS; BODY WEIGHT; BONE DENSITY; BONE DISEASES, METABOLIC; CALCIUM; CORDYCEPS; DRUG ADMINISTRATION SCHEDULE; FEMALE; ORGAN SIZE; OSTEOPOROSIS; OVARIECTOMY; PHOSPHORUS; RATS; STRONTIUM; THYMUS GLAND; UTERUS;

ANIMALIA; CORDYCEPS; CORDYCEPS SINENSIS; FUNGI; RATTUS;

EID: 84879223117     PISSN: 01634984     EISSN: 15590720     Source Type: Journal    
DOI: 10.1007/s12011-010-8711-4     Document Type: Article

References (28)

1. Morohashi T, Sano T, Yamada S (1994) Effects of strontium on calcium metabolism in rats. I. A distinction between the pharmacological and toxic doses. Jpn J Pharmacol 64:155-162 (Pubitemid 24105137)
2. Marie PJ, Garba MT, Hott M, Miravet L (1985) Effect of low doses of stable strontium on bone metabolism in rats. Miner Electrolyte Metab 11:5-13 (Pubitemid 15181939)
3. Meunier PJ, Roux C, Seeman E, Ortolani S, Badurski JE, Spector TD, Cannata J, Balogh A, Lemmel EM, Pors-Nielsen S, Rizzoli R, Genant HK, Reginster JY (2004) The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis. N Engl J Med 350(5):459-468 (Pubitemid 38133766)
4. Reginster JY, Seeman E, De Vernejoul MC, Adami S, Compston J, Phenekos C, Devogelaer JP, Curiel MD, Sawicki A, Goemaere S, Sorensen OH, Felsenberg D, Meunier PJ (2005) Strontium ranelate reduces the risk of nonvertebral fractures in postmenopausal women with osteoporosis: treatment of peripheral osteoporosis (TROPOS) study. J Clin Endocrinol Metab 90(5):2816-2822 (Pubitemid 40686329)
5. Blake GM, Fogelman I (2006) Strontium ranelate: a novel treatment for postmenopausal osteoporosis: a review of safety and efficacy. Clin Interv Aging 1(4):367-375
6. Koh JH, Kim KM, Kim JM, Song JC et al (2003) Antifatigue and antistress effect of the hot-water fraction from mycelia of Cordyceps sinensis. Biol Pharm Bull 26:691-694
7. Bok JW, Lermer L, Chilton J, Klingeman HG et al (1999) Antitumor sterols from the mycelia of Cordyceps sinensis. Phytochemistry. Phytochemistry 51:891-898 (Pubitemid 29320865)
8. Lee H, Kim YJ, Kim HW, Lee DH et al (2006) Introduction of apoptosis Cordyceps militaries through activation of caspase-3 in leukemia HL-60 cells. Biol Pharm Bull 29:670-674
9. Li SP, Zhao KJ, Ji ZN et al (2003) A polysaccharide isolated from Cordyceps sinensis, a traditional Chinese medicine, protects PC12 cells against hydrogen peroxide-induced injury. Life Sci 73:2503-2513 (Pubitemid 37101046)
10. Yamaguchi Y, Kagota S, Nakamura K, Shinozuka K, Kunitomo M (2000) Antioxidant activity of the extracts from fruiting bodies of cultured Cordyceps sinensis. Phytother Res 14:647-649
11. Kuo YC, Tsai WJ, Wang JY, Chang SC (2001) Regulation of bronchoalveolar lavage fluids cell function by the immunomodulatory agents from Cordyceps sinensis. Life Sci 68:1067-1082
12. Koh JH, Yu KW, Suh HJ, Choi YM et al (2002) Activation of macrophages and the intestinal immune system by an orally administered decoction from cultured mycelia of Cordyceps sinensis. Biosci Biotechnol Biochem 66:407-411
13. Wu Y, Sun H, Qin F, Pan Y, Sun C (2006) Effect of various extracts and a polysaccharide from the edible mycelia of Cordyceps sinensis on cellular and humoral immune response against ovalbumin in mice. Phytother Res 20:646-652
14. Zhang G, Huang Y, Bian Y, Wong JH et al (2006) Hypoglycemic activity of the fungi Cordyceps militaries, Cordyceps sinensis, tricholoma mongolicum, and omphalia lapidescens in streptozottocin-induced diabetic rats. Appl Microbiol Biotechnol 72:1152-1156 (Pubitemid 44564448)
15. Balon TW, Jasman AP, Zhu JS (2002) A fermentation product of Cordyceps sinensis increases wholebody insulin sensitivity in rats. J Altern Complement Med 2002(8):315-323 (Pubitemid 34753406)
16. Canalis E (2009) New treatment modalities in osteoporosis. Endocr Pract 2010 29:1-23
17. Wang SM, Lee LJ, Lin WW, Chang CM (1998) Effects of a water-soluble extract of Cordyceps sinensis on steroidogenesis and capsular morphology of lipid droplets in cultured rat adrenocortical cells. J Cell Biochem 69:483-489
18. Chunchao H, Junhua Y, Yingzi W, Lingjun L (2006) Hypoglycemic activity of fermented mushroom of Coprinus comatus rich in vanadium. J Trace Elem Med Biol 20:191-196
19. Han C, Cui B, Wang Y (2008) Vanadium uptake by biomass of Coprinus comatus and their effect on hyperglycemic mice. Biol Trace Elem Res 124(1):35-39
20. Han C, Liu T (2009) A comparison of hypoglycemic activity of three species of basidiomycetes rich in vanadium. Biol Trace Elem Res 127(2):177-182
21. Weiss J, Taylor GR, Zimmermann F, Nebendahl K (2000) Collection of body fluids. In: Laboratory rat book. New York: Academic Press, pp 485-510
22. Changrani NR, Chonkar A, Adeghate E (2006) Effects of streptozotocininduced type 1 diabetes mellitus on total protein concentrations and cation contents in the isolated pancreas, parotid, submandibular, and lacrimal glands of rats. Ann N Y Acad Sci 1084:503-519 (Pubitemid 47091953)
23. Ma Z, Fu Q (2009) Comparison of the therapeutic effects of yeast-incorporated gallium with those of inorganic gallium on ovariectomized osteopenic rats. Biol Trace Elem Res. Aug 4. [Epub ahead of print]
24. Huang BM, Hsiao KY, Chuang PC, Wu MH, Pan HA, Tsai SJ (2004) Upregulation of steroidogenic enzymes and ovarian 17beta-estradiol in human granulosa-lutein cells by Cordyceps sinensis mycelium. Biol Reprod 70(5):1358-1364
25. Tsunoo A, Taketomo N, Tsuboi H, Kamijo MA et al (1995) Cordyceps sinensis: its diverse effects on mammals in vitro and in vivo. In: New Initiatives in Mycological Research, pp. 1-10
26. Halpern GM (1990) Cordyceps. In: Altieri JT (ed) China's healing mushroom. Avery Publishing Group Press, New York, pp 1-95
27. Yao W, Tian XY, Chen J et al (2007) Rolipram, a phosphodiesterase 4 inhibitor, prevented cancellous and cortical bone loss by inhibiting endosteal bone resorption and maintaining the elevated periosteal bone formation in adult ovariectomized rats. J Musculoskelet Neuronal Interact 7(2):119-130 (Pubitemid 47249001)
28. Tomita A (1990) Osteoporosis-blood biochemistry. Jpn J Clin Med 48:2838-2844