Zinc deficiency enhances the induction of micronuclei and 8-hydroxy-2′-deoxyguanosine via superoxide radical in bone marrow of zinc-deficient rats

Biological Trace Element Research

Volumn 154, Issue 1, 2013, Pages 120-126

  Kawasaki, Ichiro ^a   Suzuki, Yuji ^a   Yanagisawa, Hiroyuki ^a  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

8 OHdG; Micronucleus; Oxidative stress; Superoxide; Zinc deficiency

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; COPPER ZINC SUPEROXIDE DISMUTASE; SUPEROXIDE; TEMPOL; ZINC;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; COPPER BLOOD LEVEL; DIET SUPPLEMENTATION; MALE; MICRONUCLEUS; NONHUMAN; OXIDATIVE STRESS; RAT; WEIGHT GAIN; ZINC BLOOD LEVEL; ZINC DEFICIENCY;

ANIMALS; BIOLOGICAL MARKERS; BODY WEIGHT; BONE MARROW; COPPER; DEOXYGUANOSINE; DIET; DIETARY SUPPLEMENTS; MALE; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MICRONUCLEUS TESTS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; SUPEROXIDES; ZINC;

RATTUS;

EID: 84879222127     PISSN: 01634984     EISSN: 15590720     Source Type: Journal    
DOI: 10.1007/s12011-013-9706-8     Document Type: Article

References (32)

1. Vallee BL, Falchuk KH (1993) The biochemical basis of zinc physiology. Physiol Rev 73:79-118
2. Yanagisawa H (2008) Zinc deficiency and clinical practice - validity of zinc preparations. Yakugaku Zasshi 123(3):333-339
3. Kubori S, Kurasawa R, Okada S, Kamioka H, Kogirima M, Takano S, Yamaura E (2006) Differences in the serum level of rural and urban residents in a city in the central part of Japan, examined at annual community-wide health examination. Biomed Res Trace Elem 17:335-338
4. Bruce NA (2001) DNA damage from micronutrient deficiencies is likely to be a major cause of cancer. Mutat Res 475:7-20
5. Ho E, Ames BN (2002) Low intracellular zinc induces oxidative DNA damage, disrupts p53, NFκB, and AP1 DNA binding, and affects DNA repair in a rat glioma cell line. Proc Natl Acad Sci 99:16770-16775
6. Ho E (2004) Zinc deficiency, DNA damage and cancer risk. J Nutr Biochem 15:572-578
7. Song Y, Leonard SW, Traber MG, Ho E (2009) Zinc deficiency affects DNA damage, oxidative stress, antioxidant defenses, and DNA repair in rats. J Nutr 139(9):1626
8. Wan S-G, Taccioli C, Jiang Y, Chen H, Smalley KJ, Huang K, Liu XP, Farber JL, Croce CM, Fong LY (2010) Zinc deficiency activates S100A8 inflammation in the absence of COX-2 and promotes murine oral-esophageal tumor progression. Int J Cancer 129:331-345
9. Taccioli C, Chen H, Jiang Y, Liu XP, Huang K, Smalley KJ, Farber JL, Croce CM, Fong LY (2012) Dietary zinc deficiency fuels esophageal cancer development by inducing a distinct inflammatory signature. Oncogene 31(42):4550-4558. doi: 10.1038/onc.2011.592
10. Kurihara N, Yanagisawa H, Sato M, Tien CK, Wada O (2002) Increased renal vascular resistance in zinc-deficient rats: role of nitric oxide and superoxide. Clin Exp Pharmacol P 29:1096-1104
11. Sato M, Yanagisawa H, Nojima Y, Tamura J, Wada O (2002) Zn deficiency aggravates hypertension in spontaneously hypertensive rats: possible role of Cu/Zn-superoxide dismutase. Clin Exp Hypertens 24(5):355-370
12. Naziroǧlu M (2007) New molecular mechanisms on the activation of TRPM2 channels by oxidative stress and ADP-ribose. Neurochem Res 32:1990-2001
13. Wogan GN, Hecht SS, Felton JS, Conney AH, Loeb LA (2004) Environmental and chemical carcinogenesis. Semin Cancer Biol 14(6):473-486
14. Hernández LG, van Steeg H, Lujiten M, van Benthem J (2009) Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approach. Mutat Res 682(2-3):94-109
15. Yanagisawa H, Moridaira K, Wada O (2000) Zinc deficiency further increases the enhanced expression of endothelin-1 in glomeruli of the obstructed kidney. Kidney Int 58:575-586
16. Yanagisawa H, Sato M, Nodera M, Wada O (2004) Excessive zinc intake elevates systemic blood pressure levels in normotensive rats - potential role of superoxide-induced oxidative stress. J Hypertens 22:543-550
17. Miyakoshi Y, Kajihara C, Shimizu H, Yanagisawa H (2012) Tempol suppresses micronuclei formation in astrocytes of newborn rats exposed to 50-Hz, 10-mT electromagnetic fields under bleomycin administration. Mutat Res-Genet Toxicol Environ 747:138-141
18. Suzuki Y, Takagi R, Kawasaki I, Matsudaira T, Yanagisawa H, Shimizu H (2008) The micronucleus test and erythropoiesis: effects of cyclic adenosine monophosphate (cAMP) on micronucleus formation. Mutat Res-Genet Toxicol Environ 655:47-51
19. Higurashi K, Iizuka N, Yoshimura H, Tanaka T, Nomoto S (2007) Evaluation of colorimetric method for zinc, using clinical chemistry analyzer. Biomed Res Trace Elem 18:380-385
20. Schmid W (1976) The micronucleus test for cytogenetic analysis. In: Hollaender A (ed) Chemical mutagenesis, vol. 4. Plenum, New York, pp 31-53
21. Suzuki Y, Shimizu H, Nagae Y, Fukumoto M, Okonogi H, Kadokura M (1993) The micronucleus test and erythropoiesis. Effect of cobalt on the induction of micronuclei by mutagens. Environ Mol Mutagen 22:101-106
22. 2 on the micronucleus formation in mouse bone marrow cells by various mutagens. Mutat Res 311:287-293
23. Takagi R, Suzuki Y, Seki Y, Ikehata M, Kajihara C, Shimizu H, Yanagisawa H (2011) Indium chloride-induced micronuclei in vivo and in vitro experimental systems. J Occup Health 53:102-109
24. Nebot C, Moutet M, Huet P, Xu JZ, Yadan JC, Chaudiere J (1993) Spectrophotometric assay of superoxide dismutase activity based on the activated autoxidation of a tetracyclic catechol. Anal Biochem 214(2):442-451
25. Yoshida D, Ikeda Y, Nakazawa S (1993) Suppression of 9L gliosarcoma growth by copper depletion with copper-deficient diet and d-penicillamine. J Neuro-Oncol 17:91-97
26. Jing MY, Sun JY, Weng XY, Wang JF (2008) Effects of Zn levels on activities of gastrointestinal enzymes in growing rats. J Anim Physiol An N (Berl) 93:606-612
27. MacGregor JT (1990) Dietary factors affecting spontaneous chromosomal damage in man. Clin Biol Res 347:139-153
28. Naziroǧlu M (2009) Role of selenium on calcium signaling and oxidative stress-induced molecular pathways in epilepsy. Neurochem Res 34(12):2181-2191
29. 2+ signaling on molecular pathways of neuropathic pain in diabetes: focus on TRP channels. Neurochem Res 37(10):2065-2075
30. Taysi S, Cikman O, Kaya A, Demircan B, Gumustekin K, Yilmaz A, Boyuk A, Keles M, Akyuz M, Turkeli M (2008) Increased oxidant stress and decreased antioxidant status in erythrocytes of rats fed with zinc-deficient diet. Biol Trace Elem Res 123:161-167
31. Lewinska A, Wnuk M, Slota E, Bartosz G (2008) The nitroxide antioxidant tempol affects metal-induced cyto- and genotoxicity in human lymphocytes in vitro. Mutat Res-Genet Toxicol Environ 649:7-14
32. Sinha D, Roy M (2011) Antagonistic role of tea against sodium arsenite-induced oxidative DNA damage and inhibition of DNA repair in Swiss albino mice. J Environ Pathol Toxicol Oncol 300(4):311-322 Technology