Dynamic bioluminescence imaging for quantitative tumour burden assessment using IV or IP administration of d-luciferin: Effect on intensity, time kinetics and repeatability of photon emission

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 35, Issue 5, 2008, Pages 999-1007

  Keyaerts, Marleen ^a,b   Verschueren, Jacob ^c   Bos, Tomas J ^a   Tchouate Gainkam, Lea Olive ^a   Peleman, Cindy ^a   Breckpot, Karine ^a   Vanhove, Chris ^a,b   Caveliers, Vicky ^a,b   Bossuyt, Axel ^a,b   Lahoutte, Tony ^a,b  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b UNIVERSITY HOSPITAL BRUSSELS   (Belgium)

^c UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Animal model; Bioluminescence imaging; Molecular imaging; Small animal imaging; Tumour imaging

Indexed keywords

LUCIFERIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLUMINESCENCE; CELL COUNT; CONTROLLED STUDY; CORRELATION ANALYSIS; HISTOLOGY; HUMAN; HUMAN CELL; IMAGING SYSTEM; IN VITRO STUDY; IN VIVO STUDY; KINETICS; MALE; MOUSE; NONHUMAN; PHOTON EMISSION TOMOGRAPHY; STATISTICAL SIGNIFICANCE; TUMOR VOLUME;

ANIMALS; CELL LINE, TUMOR; CONTRAST MEDIA; FIREFLY LUCIFERIN; INJECTIONS, INTRAPERITONEAL; INJECTIONS, INTRAVENOUS; KINETICS; LIGHT; LUMINESCENT MEASUREMENTS; MALE; MICE; MICE, NUDE; RHABDOMYOSARCOMA;

EID: 42149086160     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-007-0664-2     Document Type: Article

References (24)

1. Kim SA, Kim YC, Kim SW, et al. Antitumor activity of novel indirubin derivatives in rat tumor model. Clin Cancer Res 2007;13(1):253-9.
2. Rehemtulla A, Stegman LD, Cardozo SJ, et al. Rapid and quantitative assessment of cancer treatment response using in vivo bioluminescence imaging. Neoplasia 2000;2(6):491-5.
3. Jenkins DE, Oei Y, Hornig YS, et al. Bioluminescent imaging (BLI) to improve and refine traditional murine models of tumor growth and metastasis. Clin Exp Metastasis 2003;20(8):733-44.
4. Contag CH, Jenkins D, Contag PR, Negrin RS. Use of reporter genes for optical measurements of neoplastic disease in vivo. Neoplasia 2000;2(1-2):41-52.
5. Contag PR, Olomu IN, Stevenson DK, Contag CH. Bioluminescent indicators in living mammals. Nat Med 1998;4(2):245-7.
6. Hastings JW. Chemistries and colors of bioluminescent reactions: a review. Gene 1996;173(1 Spec):5-11.
7. Wood KV, Lam YA, McElroy WD. Introduction to beetle luciferases and their applications. J Biolumin Chemilumin 1989;4(1):289-301.
8. Breckpot K, Dullaers M, Bonehill A, et al. Lentivirally transduced dendritic cells as a tool for cancer immunotherapy. J Gene Med 2003;5(8):654-7.
9. Breckpot K, Heirman C, De Greef C, van der Bruggen P, Thielemans K. Identification of new antigenic peptide presented by HLA-Cw7 and encoded by several MAGE genes using dendritic cells transduced with lentiviruses. J Immunol 2004;172(4):2232-7.
10. De Jonge F, Van Nassauw L, Van Meir F, Miller HR, Van Marck E, Timmermans JP. Temporal distribution of distinct mast cell phenotypes during intestinal schistosomiasis in mice. Parasite Immunol 2002;24(5):225-31.
11. Frundzhyan V, Ugarova N. Bioluminescent assay of total bacterial contamination of drinking water. Luminescence 2007;22(3):241-4.
12. Higashi T, Isomoto A, Tyuma I, Kakishita E, Uomoto M, Nagai K. Quantitative and continuous analysis of ATP release from blood platelets with firefly luciferase luminescence. Thromb Haemost 1985;53(1):65-9.
13. Levin CS. Primer on molecular imaging technology. Eur J Nucl Med Mol Imaging 2005;32(Suppl 2):S325-45.
14. Contag CH, Spilman SD, Contag PR, et al. Visualizing gene expression in living mammals using a bioluminescent reporter. Photochem Photobiol 1997;66(4):523-31.
15. Edinger M, Sweeney TJ, Tucker AA, Olomu AB, Negrin RS, Contag CH. Noninvasive assessment of tumor cell proliferation in animal models. Neoplasia 1999;1(4):303-10.
16. Paroo Z, Bollinger RA, Braasch DA, et al. Validating bioluminescence imaging as a high-throughput, quantitative modality for assessing tumor burden. Mol Imaging 2004;3(2):117-24.
17. Burgos JS, Rosol M, Moats RA, et al. Time course of bioluminescent signal in orthotopic and heterotopic brain tumors in nude mice. Biotechniques 2003;34(6):1184-8.
18. Wu JC, Sundaresan G, Iyer M, Gambhir SS. Noninvasive optical imaging of firefly luciferase reporter gene expression in skeletal muscles of living mice. Molec Ther 2001;4(4):297-306.
19. Wang W, El-Deiry WS. Bioluminescent molecular imaging of endogenous and exogenous p53-mediated transcription in vitro and in vivo using an HCT116 human colon carcinoma xenograft model. Cancer Biol Ther 2003;2(2):196-202.
20. Avram MJ, Krejcie TC, Niemann CU, Enders-Klein C, Shanks CA, Henthorn TK. Isoflurane alters the recirculatory pharmacokinetics of physiologic markers. Anesthesiology 2000;92(6):1757-68.
21. Baba S, Cho SY, Ye Z, Cheng L, Engles JM, Wahl RL. How reproducible is bioluminescent imaging of tumor cell growth? Single time point versus the dynamic measurement approach. Mol Imaging 2007;6(5):315-22.
22. Edinger M, Cao YA, Hornig YS, et al. Advancing animal models of neoplasia through in vivo bioluminescence imaging. Eur J Cancer 2002;38(16):2128-36.
23. Sarraf-Yazdi S, Mi J, Dewhirst MW, Clary BM. Use of in vivo bioluminescence imaging to predict hepatic tumor burden in mice. J Surg Res 2004;120(2):249-55.
24. Scatena CD, Hepner MA, Oei YA, et al. Imaging of bioluminescent LNCaP-luc-M6 tumors: a new animal model for the study of metastatic human prostate cancer. Prostate 2004;59(3):292-303.