Lessons from look-back in acute liver failure? A single centre experience of 3300 patients

Journal of Hepatology

Volumn 59, Issue 1, 2013, Pages 74-80

  Bernal, William ^a   Hyyrylainen, Anna ^a   Gera, Amit ^a   Audimoolam, Vinod K ^a   McPhail, Mark J W ^a   Auzinger, Georg ^a   Rela, Mohammed ^a   Heaton, Nigel ^a   O'Grady, John G ^a   Wendon, Julia ^a   Williams, Roger ^b  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b INSTITUTE OF HEPATOLOGY   (United Kingdom)

Author keywords

Acute liver failure; Critical care; Outcomes; Transplantation

Indexed keywords

BILIRUBIN; CREATININE; HALOTHANE; PARACETAMOL; SODIUM;

ACUTE LIVER FAILURE; ADULT; ARTICLE; BILIRUBIN BLOOD LEVEL; BLOOD CLOTTING DISORDER; CREATININE BLOOD LEVEL; DISEASE SEVERITY; EMERGENCY SURGERY; FEMALE; HEPATIC ENCEPHALOPATHY; HEPATITIS A; HEPATITIS B; HOSPITAL ADMISSION; HUMAN; HYPERTENSION; INTENSIVE CARE; INTERNATIONAL NORMALIZED RATIO; INTRACRANIAL HYPERTENSION; LIVER DYSFUNCTION; LIVER INJURY; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MORTALITY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; SODIUM BLOOD LEVEL; SURVIVAL; TOXIC HEPATITIS;

ACETAMINOPHEN; ADULT; ANALGESICS, NON-NARCOTIC; EMERGENCIES; FEMALE; HEPATIC ENCEPHALOPATHY; HUMANS; INTENSIVE CARE; INTRACRANIAL HYPERTENSION; LIVER FAILURE, ACUTE; LIVER TRANSPLANTATION; LONDON; MALE; MIDDLE AGED; RISK FACTORS; YOUNG ADULT;

EID: 84879160065     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2013.02.010     Document Type: Article

References (37)

1. P. Ichai, and D. Samuel Etiology and prognosis of fulminant hepatitis in adults Liver Transpl 14 2008 S67 S79
2. W. Bernal, G. Auzinger, A. Dhawan, and J. Wendon Acute liver failure Lancet 376 2010 190 201
3. R.T. Stravitz Critical management decisions in patients with acute liver failure Chest 134 2008 1092 1102
4. W. Bernal, C. Hall, C.J. Karvellas, G. Auzinger, E. Sizer, and J. Wendon Arterial ammonia and clinical risk factors for encephalopathy and intracranial hypertension in acute liver failure Hepatology 46 2007 1844 1852
5. S.K. Acharya, V. Bhatia, V. Sreenivas, S. Khanal, and S.K. Panda Efficacy of l-ornithine l-aspartate in acute liver failure: a double-blind, randomized, placebo-controlled study [see comment] Gastroenterology 136 2009 2159 2168
6. A. Escorsell, A. Mas, and M. de la Mata Spanish Group for the Study of Acute Liver F. Acute liver failure in Spain: analysis of 267 cases [see comment] Liver Transpl 13 2007 1389 1395
7. W.A. Bower, M. Johns, H.S. Margolis, I.T. Williams, and B.P. Bell Population-based surveillance for acute liver failure [erratum appears in Am J Gastroenterol. 2008 Jan;103(1):255] Am J Gastroenterol 102 2007 2459 2463
8. W. Bernal, G. Auzinger, E. Sizer, and J. Wendon Intensive care management of acute liver failure Semin Liver Dis 28 2008 188 200
9. R.T. Stravitz, A.H. Kramer, T. Davern, A.O.S. Shaikh, S.H. Caldwell, and R.L. Mehta Intensive care of patients with acute liver failure: recommendations of the US. Acute Liver Failure Study Group Crit Care Med 35 2007 2498 2508
10. K. Hawton, S. Simkin, J. Deeks, J. Cooper, A. Johnston, and K. Waters UK Legislation on analgesic packs: before and after study of long term effect on poisonings Br Med J 329 2004 1076 1081
11. J.S. Bajaj, J. Cordoba, K.D. Mullen, P. Amodio, D.L. Shawcross, and R.F. Butterworth Review article: the design of clinical trials in hepatic encephalopathy-an International Society for Hepatic Encephalopathy and Nitrogen Metabolism (ISHEN) consensus statement Aliment Pharmacol Ther 33 2011 739 747
12. R.T. Stravitz, T. Lisman, V.A. Luketic, R.K. Sterling, P. Puri, and M. Fuchs Minimal effects of acute liver injury/acute liver failure on hemostasis as assessed by thromboelastography J Hepatol 56 2012 129 136
13. J.G. O'Grady Acute liver failure B.R. Bacon, A.M. Di Bisceglie, J.G. O'Grady, J.R. Lake, Comprehensive clinical hepatology 2006 Elsevier Philadelphia 515 535
14. N. Murphy, G. Auzinger, W. Bernal, and J. Wendon The effect of hypertonic sodium chloride on intracranial pressure in patients with acute liver failure Hepatology 39 2004 464 470
15. N. Rolando, J. Wade, M. Davalos, J. Wendon, J. Philpott-Howard, and R. Williams The systemic inflammatory response syndrome in acute liver failure Hepatology 32 2000 734 739
16. J.G. O'Grady, G.J. Alexander, K.M. Hayllar, and R. Williams Early indicators of prognosis in fulminant hepatic failure Gastroenterology 97 1989 439 445
17. J. Neuberger, A. Gimson, M. Davies, M. Akyol, J. O'Grady, and A. Burroughs Selection of patients for liver transplantation and allocation of donated livers in the UK [see comment] Gut 57 2008 252 257
18. W. Bernal, T.J.S. Cross, G. Auzinger, E. Sizer, M.A. Heneghan, and M. Bowles Outcome after wait-listing for emergency liver transplantation in acute liver failure: a single centre experience J Hepatol 50 2009 306 313
19. K.A. Wlodzimirow, S. Eslami, A. Abu-Hanna, M. Nieuwoudt, and R.A.F.M. Chamuleau Systematic review: acute liver failure-one disease, more than 40 definitions Aliment Pharmacol Ther 35 2012 1245 1256
20. C. Probst, H.-C. Pape, F. Hildebrand, G. Regel, L. Mahlke, and P. Giannoudis 30 years of polytrauma care: an analysis of the change in strategies and results of 4849 cases treated at a single institution Injury 40 2009 77 83
21. T.A. Gooley, J.W. Chien, S.A. Pergam, S. Hingorani, M.L. Sorror, and M. Boeckh Reduced mortality after allogeneic hematopoietic-cell transplantation N Engl J Med 363 2010 2091 2101
22. R.M. Taylor, T. Davern, S. Munoz, S.-H. Han, B. McGuire, and A.M. Larson Fulminant hepatitis A virus infection in the United States: incidence, prognosis, and outcomes [see comment] Hepatology 44 2006 1589 1597
23. V. Bhatia, A. Singhal, S.K. Panda, and S.K. Acharya A 20-year single-center experience with acute liver failure during pregnancy: is the prognosis really worse? [see comment] Hepatology 48 2008 1577 1585
24. S.K. Acharya, Y. Batra, S. Hazari, V. Choudhury, S.K. Panda, and S. Dattagupta Etiopathogenesis of acute hepatic failure: eastern versus Western countries J Gastroenterol Hepatol 17 2002 S268 S273
25. W. Bernal Changing patterns of causation and the use of transplantation in the United Kingdom Semin Liver Dis 23 2003 227 237
26. O. Morgan, and A. Majeed Restricting paracetamol in the United Kingdom to reduce poisoning: a systematic review J Public Health 27 2005 12 18
27. D.G.N. Craig, C.M. Bates, J.S. Davidson, K.G. Martin, P.C. Hayes, and K.J. Simpson Staggered overdose pattern and delay to hospital presentation are associated with adverse outcomes following paracetamol-induced hepatotoxicity Br J Clin Pharmacol 73 2012 285 294
28. C. Yaghi, K. Honein, J. Boujaoude, R. Slim, R. Moucari, and R. Sayegh Influence of acetaminophen at therapeutic doses on surrogate markers of severity of acute viral hepatitis Gastroenterol Clin Biol 30 2006 763 768
29. G. Rezende, A.M. Roque-Afonso, D. Samuel, M. Gigou, E. Nicand, and V. Ferre Viral and clinical factors associated with the fulminant course of hepatitis A infection Hepatology 38 2003 613 618
30. N. Khandelwal, L.P. James, C. Sanders, A.M. Larson, W.M. Lee, and The Acute Liver Failure Study G Unrecognized acetaminophen toxicity as a cause of indeterminate acute liver failure Hepatology 53 2011 567 576
31. W.M. Lee, L.S. Hynan, L. Rossaro, R.J. Fontana, R.T. Stravitz, and A.M. Larson Intravenous N-acetylcysteine improves transplant-free survival in early stage non-acetaminophen acute liver failure Gastroenterology 137 2009 856 864
32. A.T. Blei Medical therapy of brain edema in fulminant hepatic failure Hepatology 32 2000 666 669
33. V. Bhatia, R. Singh, and S.K. Acharya Predictive value of arterial ammonia for complications and outcome in acute liver failure Gut 55 2006 98 104
34. J. Vaquero, J. Polson, C. Chung, I. Helenowski, F.V. Schiodt, and J. Reisch Infection and the progression of hepatic encephalopathy in acute liver failure Gastroenterology 125 2003 755 764
35. C.J. Karvellas, F. Pink, M. McPhail, T. Cross, G. Auzinger, and W. Bernal Predictors of bacteraemia and mortality in patients with acute liver failure Intensive Care Med 35 2009 1390 1396
36. G. Ostapowicz, R.J. Fontana, F.V. Schiodt, A. Larson, T.J. Davern, and S.H. Han Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States Ann Intern Med 137 2002 947 954
37. K. Vagnerova, I.P. Koerner, and P.D. Hurn Gender and the injured brain Anesth Analg 107 2008 201 214