메뉴 건너뛰기




Volumn 13, Issue 3, 2013, Pages 449-454

Targeting mechanotransduction pathways in osteoarthritis: A focus on the pericellular matrix

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN; AGGRECAN; AGGRECANASE 2; BIGLYCAN; BONE MORPHOGENETIC PROTEIN 2; COLLAGEN TYPE 2; COLLAGEN TYPE 6; COLLAGENASE 3; CONNECTIVE TISSUE GROWTH FACTOR; DISCOIDIN; FIBRILLIN; FIBROBLAST GROWTH FACTOR 18; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR 3; FIBULIN; HEPARAN SULFATE; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; INTEGRIN; PERLECAN; PLATELET DERIVED GROWTH FACTOR; PROTEOGLYCAN; SOMATOMEDIN; SULFOTRANSFERASE; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN; WNT3A PROTEIN;

EID: 84879106157     PISSN: 14714892     EISSN: 14714973     Source Type: Journal    
DOI: 10.1016/j.coph.2013.01.010     Document Type: Review
Times cited : (99)

References (61)
  • 1
    • 0348111231 scopus 로고    scopus 로고
    • Longitudinal analysis of cartilage atrophy in the knees of patients with spinal cord injury
    • B. Vanwanseele, F. Eckstein, H. Knecht, A. Spaepen, and E. Stüssi Longitudinal analysis of cartilage atrophy in the knees of patients with spinal cord injury Arthritis Rheum 48 2003 3377 3381
    • (2003) Arthritis Rheum , vol.48 , pp. 3377-3381
    • Vanwanseele, B.1    Eckstein, F.2    Knecht, H.3    Spaepen, A.4    Stüssi, E.5
  • 2
    • 0019976206 scopus 로고
    • Immobilization of the knee prevents osteoarthritis after anterior cruciate ligament transection
    • M.J. Palmoski, and K.D. Brandt Immobilization of the knee prevents osteoarthritis after anterior cruciate ligament transection Arthritis Rheum 25 1982 1201 1208
    • (1982) Arthritis Rheum , vol.25 , pp. 1201-1208
    • Palmoski, M.J.1    Brandt, K.D.2
  • 3
    • 0018583502 scopus 로고
    • Development and reversal of a proteoglycan aggregation defect in normal canine knee cartilage after immobilization
    • M. Palmoski, E. Perricone, and K.D. Brandt Development and reversal of a proteoglycan aggregation defect in normal canine knee cartilage after immobilization Arthritis Rheum 22 1979 508 517
    • (1979) Arthritis Rheum , vol.22 , pp. 508-517
    • Palmoski, M.1    Perricone, E.2    Brandt, K.D.3
  • 4
    • 70349395238 scopus 로고    scopus 로고
    • Commentary: Is it useful to subset "primary" osteoarthritis? A critique based on evidence regarding the etiopathogenesis of osteoarthritis
    • K.D. Brandt, P. Dieppe, and E.L. Radin Commentary: is it useful to subset "primary" osteoarthritis? A critique based on evidence regarding the etiopathogenesis of osteoarthritis Semin Arthritis Rheum 39 2009 81 95
    • (2009) Semin Arthritis Rheum , vol.39 , pp. 81-95
    • Brandt, K.D.1    Dieppe, P.2    Radin, E.L.3
  • 5
    • 34748813185 scopus 로고    scopus 로고
    • The long-term consequence of anterior cruciate ligament and meniscus injuries: Osteoarthritis
    • L.S. Lohmander, P.M. Englund, L.L. Dahl, and E.M. Roos The long-term consequence of anterior cruciate ligament and meniscus injuries: osteoarthritis Am J Sports Med 35 2007 1756 1769
    • (2007) Am J Sports Med , vol.35 , pp. 1756-1769
    • Lohmander, L.S.1    Englund, P.M.2    Dahl, L.L.3    Roos, E.M.4
  • 6
    • 78650977864 scopus 로고    scopus 로고
    • Genetic epidemiology of hip and knee osteoarthritis
    • A.M. Valdes, and T.D. Spector Genetic epidemiology of hip and knee osteoarthritis Nat Rev Rheumatol 7 2011 23 32
    • (2011) Nat Rev Rheumatol , vol.7 , pp. 23-32
    • Valdes, A.M.1    Spector, T.D.2
  • 7
    • 0030737497 scopus 로고    scopus 로고
    • Is hormone replacement therapy protective for hand and knee osteoarthritis in women?: The Chingford Study
    • T.D. Spector, D. Nandra, D.J. Hart, and D.V. Doyle Is hormone replacement therapy protective for hand and knee osteoarthritis in women?: the Chingford Study Ann Rheum Dis 56 1997 432 434
    • (1997) Ann Rheum Dis , vol.56 , pp. 432-434
    • Spector, T.D.1    Nandra, D.2    Hart, D.J.3    Doyle, D.V.4
  • 9
    • 84867812304 scopus 로고    scopus 로고
    • Mapping pathogenesis of arthritis through small animal models
    • for the Arthritis Research UK Animal Models Working Group 10.1093/rheumatology/kes035
    • T.L. Vincent, R.O. Williams, R. Maciewicz, A. Silman, P. Garside for the Arthritis Research UK Animal Models Working Group Mapping pathogenesis of arthritis through small animal models Rheumatology (Oxf) 2012 10.1093/rheumatology/kes035
    • (2012) Rheumatology (Oxf)
    • Vincent, T.L.1    Williams, R.O.2    Maciewicz, R.3    Silman, A.4    Garside, P.5
  • 11
    • 73249137617 scopus 로고    scopus 로고
    • Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development
    • C.B. Little, A. Barai, D. Burkhardt, S.M. Smith, A.J. Fosang, Z. Werb, M. Shah, and E.W. Thompson Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development Arthritis Rheum 60 2009 3723 3733
    • (2009) Arthritis Rheum , vol.60 , pp. 3723-3733
    • Little, C.B.1    Barai, A.2    Burkhardt, D.3    Smith, S.M.4    Fosang, A.J.5    Werb, Z.6    Shah, M.7    Thompson, E.W.8
  • 12
    • 84863226474 scopus 로고    scopus 로고
    • Joint immobilization prevents murine osteoarthritis and reveals the highly mechanosensitive nature of protease expression in vivo
    • A. Burleigh, A. Chanalaris, M.D. Gardiner, C. Driscoll, O. Boruc, J. Saklatvala, and T.L. Vincent Joint immobilization prevents murine osteoarthritis and reveals the highly mechanosensitive nature of protease expression in vivo Arthritis Rheum 64 2012 2278 2288
    • (2012) Arthritis Rheum , vol.64 , pp. 2278-2288
    • Burleigh, A.1    Chanalaris, A.2    Gardiner, M.D.3    Driscoll, C.4    Boruc, O.5    Saklatvala, J.6    Vincent, T.L.7
  • 13
    • 0036845171 scopus 로고    scopus 로고
    • Clinical benefit of joint distraction in the treatment of severe osteoarthritis of the ankle: Proof of concept in an open prospective study and in a randomized controlled study
    • A.C.A. Marijnissen, P.M. Van Roermund, J. Van Melkebeek, W. Schenk, A.J. Verbout, J.W.J. Bijlsma, and F.P.J.G. Lafeber Clinical benefit of joint distraction in the treatment of severe osteoarthritis of the ankle: proof of concept in an open prospective study and in a randomized controlled study Arthritis Rheum 46 2002 2893 2902
    • (2002) Arthritis Rheum , vol.46 , pp. 2893-2902
    • Marijnissen, A.C.A.1    Van Roermund, P.M.2    Van Melkebeek, J.3    Schenk, W.4    Verbout, A.J.5    Bijlsma, J.W.J.6    Lafeber, F.P.J.G.7
  • 14
    • 84863582846 scopus 로고    scopus 로고
    • Motion versus fixed distraction of the joint in the treatment of ankle osteoarthritis: A prospective randomized controlled trial
    • C.L. Saltzman, S.L. Hillis, M.P. Stolley, D.D. Anderson, and A. Amendola Motion versus fixed distraction of the joint in the treatment of ankle osteoarthritis: a prospective randomized controlled trial J Bone Joint Surg Am 94 2012 961 970
    • (2012) J Bone Joint Surg Am , vol.94 , pp. 961-970
    • Saltzman, C.L.1    Hillis, S.L.2    Stolley, M.P.3    Anderson, D.D.4    Amendola, A.5
  • 16
    • 59149096940 scopus 로고    scopus 로고
    • Articular chondrocytes express connexin 43 hemichannels and P2 receptors - A putative mechanoreceptor complex involving the primary cilium?
    • M.M. Knight, S.R. McGlashan, M. Garcia, C.G. Jensen, and C.A. Poole Articular chondrocytes express connexin 43 hemichannels and P2 receptors - a putative mechanoreceptor complex involving the primary cilium? J Anat 214 2009 275 283
    • (2009) J Anat , vol.214 , pp. 275-283
    • Knight, M.M.1    McGlashan, S.R.2    Garcia, M.3    Jensen, C.G.4    Poole, C.A.5
  • 18
    • 77950648327 scopus 로고    scopus 로고
    • Transient receptor potential vanilloid 4: The sixth sense of the musculoskeletal system?
    • F. Guilak, H.A. Leddy, and W. Liedtke Transient receptor potential vanilloid 4: the sixth sense of the musculoskeletal system? Ann N Y Acad Sci 1192 2010 404 409
    • (2010) Ann N y Acad Sci , vol.1192 , pp. 404-409
    • Guilak, F.1    Leddy, H.A.2    Liedtke, W.3
  • 19
    • 69149105935 scopus 로고    scopus 로고
    • Signalling cascades in mechanotransduction: Cell-matrix interactions and mechanical loading
    • L. Ramage, G. Nuki, and D.M. Salter Signalling cascades in mechanotransduction: cell-matrix interactions and mechanical loading Scand J Med Sci Sports 19 2009 457 469
    • (2009) Scand J Med Sci Sports , vol.19 , pp. 457-469
    • Ramage, L.1    Nuki, G.2    Salter, D.M.3
  • 21
    • 0030979705 scopus 로고    scopus 로고
    • Articular cartilage chondrons: Form, function and failure
    • C.A. Poole Articular cartilage chondrons: form, function and failure J Anat 191 Pt 1 1997 1 13
    • (1997) J Anat , vol.191 , Issue.PART 1 , pp. 1-13
    • Poole, C.A.1
  • 22
    • 0036081855 scopus 로고    scopus 로고
    • Ultrastructural localization of type VI collagen in normal adult and osteoarthritic human articular cartilage
    • S. Söder, L. Hambach, R. Lissner, T. Kirchner, and T. Aigner Ultrastructural localization of type VI collagen in normal adult and osteoarthritic human articular cartilage YJOCA 10 2002 464 470
    • (2002) YJOCA , vol.10 , pp. 464-470
    • Söder, S.1    Hambach, L.2    Lissner, R.3    Kirchner, T.4    Aigner, T.5
  • 23
    • 33845997777 scopus 로고    scopus 로고
    • The structure, location, and function of perlecan, a prominent pericellular proteoglycan of fetal, postnatal, and mature hyaline cartilages
    • J. Melrose, P. Roughley, S. Knox, S. Smith, M. Lord, and J. Whitelock The structure, location, and function of perlecan, a prominent pericellular proteoglycan of fetal, postnatal, and mature hyaline cartilages J Biol Chem 281 2006 36905 36914
    • (2006) J Biol Chem , vol.281 , pp. 36905-36914
    • Melrose, J.1    Roughley, P.2    Knox, S.3    Smith, S.4    Lord, M.5    Whitelock, J.6
  • 24
    • 27244448926 scopus 로고    scopus 로고
    • The biomechanical role of the chondrocyte pericellular matrix in articular cartilage
    • L.G. Alexopoulos, L.A. Setton, and F. Guilak The biomechanical role of the chondrocyte pericellular matrix in articular cartilage Acta Biomater 1 2005 317 325
    • (2005) Acta Biomater , vol.1 , pp. 317-325
    • Alexopoulos, L.G.1    Setton, L.A.2    Guilak, F.3
  • 27
    • 33947109970 scopus 로고    scopus 로고
    • Mammalian collagen receptors
    • B. Leitinger, and E. Hohenester Mammalian collagen receptors Matrix Biol 26 2007 146 155
    • (2007) Matrix Biol , vol.26 , pp. 146-155
    • Leitinger, B.1    Hohenester, E.2
  • 28
    • 0037062469 scopus 로고    scopus 로고
    • Basic FGF mediates an immediate response of articular cartilage to mechanical injury
    • T. Vincent, M. Hermansson, M. Bolton, R. Wait, and J. Saklatvala Basic FGF mediates an immediate response of articular cartilage to mechanical injury Proc Natl Acad Sci U S A 99 2002 8259 8264
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 8259-8264
    • Vincent, T.1    Hermansson, M.2    Bolton, M.3    Wait, R.4    Saklatvala, J.5
  • 29
    • 34249987876 scopus 로고    scopus 로고
    • FGF-2 is bound to perlecan in the pericellular matrix of articular cartilage, where it acts as a chondrocyte mechanotransducer
    • T.L. Vincent, C.J. McLean, L.E. Full, D. Peston, and J. Saklatvala FGF-2 is bound to perlecan in the pericellular matrix of articular cartilage, where it acts as a chondrocyte mechanotransducer YJOCA 15 2007 752 763
    • (2007) YJOCA , vol.15 , pp. 752-763
    • Vincent, T.L.1    McLean, C.J.2    Full, L.E.3    Peston, D.4    Saklatvala, J.5
  • 30
    • 67650034636 scopus 로고    scopus 로고
    • Fibroblast growth factor 2 is an intrinsic chondroprotective agent that suppresses ADAMTS-5 and delays cartilage degradation in murine osteoarthritis
    • S.-L. Chia, Y. Sawaji, A. Burleigh, C. McLean, J. Inglis, J. Saklatvala, and T. Vincent Fibroblast growth factor 2 is an intrinsic chondroprotective agent that suppresses ADAMTS-5 and delays cartilage degradation in murine osteoarthritis Arthritis Rheum 60 2009 2019 2027
    • (2009) Arthritis Rheum , vol.60 , pp. 2019-2027
    • Chia, S.-L.1    Sawaji, Y.2    Burleigh, A.3    McLean, C.4    Inglis, J.5    Saklatvala, J.6    Vincent, T.7
  • 31
    • 80051485778 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes
    • D. Yan, D. Chen, S.M. Cool, A.J. van Wijnen, K. Mikecz, G. Murphy, and H.-J. Im Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes Arthritis Res Ther 13 2011 R130
    • (2011) Arthritis Res Ther , vol.13 , pp. 130
    • Yan, D.1    Chen, D.2    Cool, S.M.3    Van Wijnen, A.J.4    Mikecz, K.5    Murphy, G.6    Im, H.-J.7
  • 32
    • 80053965851 scopus 로고    scopus 로고
    • Fibroblast growth factor 2: Good or bad guy in the joint?
    • T.L. Vincent Fibroblast growth factor 2: good or bad guy in the joint? Arthritis Res Ther 13 2011 127
    • (2011) Arthritis Res Ther , vol.13 , pp. 127
    • Vincent, T.L.1
  • 34
    • 84870308824 scopus 로고    scopus 로고
    • Genetic inhibition of FGFR1 in cartilage attenuates articular cartilage degeneration in adult mice
    • T. Weng Genetic inhibition of FGFR1 in cartilage attenuates articular cartilage degeneration in adult mice Arthritis Rheum 64 2012 3982 3992
    • (2012) Arthritis Rheum , vol.64 , pp. 3982-3992
    • Weng, T.1
  • 35
    • 0038798680 scopus 로고    scopus 로고
    • CTGF/Hcs24, hypertrophic chondrocyte-specific gene product, interacts with perlecan in regulating the proliferation and differentiation of chondrocytes
    • T. Nishida, S. Kubota, T. Fukunaga, S. Kondo, G. Yosimichi, T. Nakanishi, T. Takano-Yamamoto, and M. Takigawa CTGF/Hcs24, hypertrophic chondrocyte-specific gene product, interacts with perlecan in regulating the proliferation and differentiation of chondrocytes J Cell Physiol 196 2003 265 275
    • (2003) J Cell Physiol , vol.196 , pp. 265-275
    • Nishida, T.1    Kubota, S.2    Fukunaga, T.3    Kondo, S.4    Yosimichi, G.5    Nakanishi, T.6    Takano-Yamamoto, T.7    Takigawa, M.8
  • 37
    • 77954527232 scopus 로고    scopus 로고
    • Bone morphogenetic protein and growth differentiation factor cytokine families and their protein antagonists
    • C.C. Rider, and B. Mulloy Bone morphogenetic protein and growth differentiation factor cytokine families and their protein antagonists Biochem J 429 2010 1 12
    • (2010) Biochem J , vol.429 , pp. 1-12
    • Rider, C.C.1    Mulloy, B.2
  • 38
    • 0036905115 scopus 로고    scopus 로고
    • Cellular actions of the insulin-like growth factor binding proteins
    • S.M. Firth, and R.C. Baxter Cellular actions of the insulin-like growth factor binding proteins Endocr Rev 23 2002 824 854
    • (2002) Endocr Rev , vol.23 , pp. 824-854
    • Firth, S.M.1    Baxter, R.C.2
  • 39
    • 36148980833 scopus 로고    scopus 로고
    • The core protein of growth plate perlecan binds FGF-18 and alters its mitogenic effect on chondrocytes
    • S.M.-L. Smith, L.A. West, and J.R. Hassell The core protein of growth plate perlecan binds FGF-18 and alters its mitogenic effect on chondrocytes Arch Biochem Biophys 468 2007 244 251
    • (2007) Arch Biochem Biophys , vol.468 , pp. 244-251
    • Smith, S.M.-L.1    West, L.A.2    Hassell, J.R.3
  • 40
    • 0141621124 scopus 로고    scopus 로고
    • Complexes of matrilin-1 and biglycan or decorin connect collagen VI microfibrils to both collagen II and aggrecan
    • C. Wiberg, A.R. Klatt, R. Wagener, M. Paulsson, J.F. Bateman, D. Heinegård, and M. Mörgelin Complexes of matrilin-1 and biglycan or decorin connect collagen VI microfibrils to both collagen II and aggrecan J Biol Chem 278 2003 37698 37704
    • (2003) J Biol Chem , vol.278 , pp. 37698-37704
    • Wiberg, C.1    Klatt, A.R.2    Wagener, R.3    Paulsson, M.4    Bateman, J.F.5    Heinegård, D.6    Mörgelin, M.7
  • 42
    • 43949145269 scopus 로고    scopus 로고
    • Identification of the molecular response of articular cartilage to injury, by microarray screening: Wnt-16 expression and signaling after injury and in osteoarthritis
    • F. Dell'Accio, C. De Bari, N.M. Eltawil, P. Vanhummelen, and C. Pitzalis Identification of the molecular response of articular cartilage to injury, by microarray screening: Wnt-16 expression and signaling after injury and in osteoarthritis Arthritis Rheum 58 2008 1410 1421
    • (2008) Arthritis Rheum , vol.58 , pp. 1410-1421
    • Dell'Accio, F.1    De Bari, C.2    Eltawil, N.M.3    Vanhummelen, P.4    Pitzalis, C.5
  • 43
    • 80052472714 scopus 로고    scopus 로고
    • A proteomic approach for identification and localization of the pericellular components of chondrocytes
    • Z. Zhang, W. Jin, J. Beckett, T. Otto, and B. Moed A proteomic approach for identification and localization of the pericellular components of chondrocytes Histochem Cell Biol 136 2011 153 162
    • (2011) Histochem Cell Biol , vol.136 , pp. 153-162
    • Zhang, Z.1    Jin, W.2    Beckett, J.3    Otto, T.4    Moed, B.5
  • 45
    • 84865408942 scopus 로고    scopus 로고
    • Specificity of latent TGF-β binding protein (LTBP) incorporation into matrix: Role of fibrillins and fibronectin
    • L. Zilberberg, V. Todorovic, B. Dabovic, M. Horiguchi, T. Couroussé, L.Y. Sakai, and D.B. Rifkin Specificity of latent TGF-β binding protein (LTBP) incorporation into matrix: Role of fibrillins and fibronectin J Cell Physiol 227 2012 3828 3836
    • (2012) J Cell Physiol , vol.227 , pp. 3828-3836
    • Zilberberg, L.1    Todorovic, V.2    Dabovic, B.3    Horiguchi, M.4    Couroussé, T.5    Sakai, L.Y.6    Rifkin, D.B.7
  • 46
    • 84855471215 scopus 로고    scopus 로고
    • The distribution of fibrillin-2 and LTBP-2, and their co-localisation with fibrillin-1 in adult bovine tail disc
    • B. Li, J.P.G. Urban, and J. Yu The distribution of fibrillin-2 and LTBP-2, and their co-localisation with fibrillin-1 in adult bovine tail disc J Anat 220 2012 164 172
    • (2012) J Anat , vol.220 , pp. 164-172
    • Li, B.1    Urban, J.P.G.2    Yu, J.3
  • 55
    • 36048970692 scopus 로고    scopus 로고
    • Mechanotransduction of bovine articular cartilage superficial zone protein by transforming growth factor beta signaling
    • C.P. Neu, A. Khalafi, K. Komvopoulos, T.M. Schmid, and A.H. Reddi Mechanotransduction of bovine articular cartilage superficial zone protein by transforming growth factor beta signaling Arthritis Rheum 56 2007 3706 3714
    • (2007) Arthritis Rheum , vol.56 , pp. 3706-3714
    • Neu, C.P.1    Khalafi, A.2    Komvopoulos, K.3    Schmid, T.M.4    Reddi, A.H.5
  • 56
    • 84864472945 scopus 로고    scopus 로고
    • Transport of fibroblast growth factor 2 in the pericellular matrix is controlled by the spatial distribution of its binding sites in heparan sulfate
    • L. Duchesne, V. Octeau, R.N. Bearon, A. Beckett, I.A. Prior, B. Lounis, and D.G. Fernig Transport of fibroblast growth factor 2 in the pericellular matrix is controlled by the spatial distribution of its binding sites in heparan sulfate PLoS Biol 10 2012 e1001361
    • (2012) PLoS Biol , vol.10 , pp. 1001361
    • Duchesne, L.1    Octeau, V.2    Bearon, R.N.3    Beckett, A.4    Prior, I.A.5    Lounis, B.6    Fernig, D.G.7
  • 57
    • 1042279596 scopus 로고    scopus 로고
    • Distribution of type VI collagen in chondrocyte microenvironment: Study of chondrons isolated from human normal and degenerative articular cartilage and cultured chondrocytes
    • O. Horikawa, H. Nakajima, T. Kikuchi, S. Ichimura, H. Yamada, K. Fujikawa, and Y. Toyama Distribution of type VI collagen in chondrocyte microenvironment: study of chondrons isolated from human normal and degenerative articular cartilage and cultured chondrocytes J Orthop Sci 9 2004 29 36
    • (2004) J Orthop Sci , vol.9 , pp. 29-36
    • Horikawa, O.1    Nakajima, H.2    Kikuchi, T.3    Ichimura, S.4    Yamada, H.5    Fujikawa, K.6    Toyama, Y.7
  • 58
    • 7744227850 scopus 로고    scopus 로고
    • Perlecan in late stages of osteoarthritis of the human knee joint
    • F. Tesche, and N. Miosge Perlecan in late stages of osteoarthritis of the human knee joint YJOCA 12 2004 852 862
    • (2004) YJOCA , vol.12 , pp. 852-862
    • Tesche, F.1    Miosge, N.2
  • 59
    • 0038374245 scopus 로고    scopus 로고
    • Alterations in the mechanical properties of the human chondrocyte pericellular matrix with osteoarthritis
    • L.G. Alexopoulos, M.A. Haider, T.P. Vail, and F. Guilak Alterations in the mechanical properties of the human chondrocyte pericellular matrix with osteoarthritis J Biomech Eng 125 2003 323 333
    • (2003) J Biomech Eng , vol.125 , pp. 323-333
    • Alexopoulos, L.G.1    Haider, M.A.2    Vail, T.P.3    Guilak, F.4
  • 60
    • 80052868968 scopus 로고    scopus 로고
    • Intact pericellular matrix of articular cartilage is required for unactivated discoidin domain receptor 2 in the mouse model
    • L. Xu, I. Polur, J.M. Servais, S. Hsieh, P.L. Lee, M.B. Goldring, and Y. Li Intact pericellular matrix of articular cartilage is required for unactivated discoidin domain receptor 2 in the mouse model Am J Pathol 179 2011 9
    • (2011) Am J Pathol , vol.179 , pp. 9
    • Xu, L.1    Polur, I.2    Servais, J.M.3    Hsieh, S.4    Lee, P.L.5    Goldring, M.B.6    Li, Y.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.