Identification of new nonsteroidal RORα ligands; Related structure-activity relationships and docking studies

ACS Medicinal Chemistry Letters

Volumn 4, Issue 6, 2013, Pages 504-508

  Dubernet, Mathieu ^a   Duguet, Nicolas ^b   Colliandre, Lionel ^b   Berini, Christophe ^b   Helleboid, Stéphane ^a   Bourotte, Marilyne ^a   Daillet, Matthieu ^b   Maingot, Lucie ^b   Daix, Sébastien ^a   Delhomel, Jean François ^a   Morin Allory, Luc ^b   Routier, Sylvain ^b   Walczak, Robert ^a  

^a Genfit SA   (France)

^b UNIVERSITÉ D'ORLÉANS   (France)

Author keywords

Agonist; Biginelli; Docking; NR1F1; ROR ; SAR

Indexed keywords

4 [4 (BENZYLOXY)PHENYL] 5 CARBONYL 2 OXO 1,2,3,4 TETRAHYDROPYRIMIDINE; HORMONE RECEPTOR STIMULATING AGENT; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CHIRAL CHROMATOGRAPHY; CHIRALITY; DRUG STRUCTURE; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH THROUGHPUT SCREENING; HYDROGEN BOND; MOLECULAR DOCKING; PRIORITY JOURNAL; RACEMIC MIXTURE; STRUCTURE ACTIVITY RELATION;

EID: 84879104078     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml300471d     Document Type: Article

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