PCR screening reveals considerable unexploited biosynthetic potential of ansamycins and a mysterious family of AHBA-containing natural products in actinomycetes

Journal of Applied Microbiology

Volumn 115, Issue 1, 2013, Pages 77-85

  Wang, H X ^a   Chen, Y Y ^b   Ge, L ^b   Fang, T T ^b   Meng, J ^a   Liu, Z ^b   Fang, X Y ^b   Ni, S ^b   Lin, C ^b   Wu, Y Y ^b   Wang, M L ^b   Shi, N N ^b   He, H G ^b   Hong, K ^c   Shen, Y M ^a,b  

^a SHANDONG UNIVERSITY   (China)

^b XIAMEN UNIVERSITY   (China)

^c WUHAN UNIVERSITY   (China)

Author keywords

AHBA synthase; AHBA containing natural products; Ansamycins; PCR screening

Indexed keywords

BACTERIA; BIOCHEMISTRY; COLUMN CHROMATOGRAPHY; GENES; KETONES; THIN LAYER CHROMATOGRAPHY;

3-AMINO-5-HYDROXYBENZOIC ACID SYNTHASE; 3-AMINO-5-HYDROXYBENZOIC ACID-CONTAINING NATURAL PRODUCT; ANSAMYCINS; GENE CLUSTERS; HYDROXYBENZOIC ACIDS; NATURAL PRODUCTS; PCR SCREENING; SYNTHASE GENE; SYNTHASES;

BIOSYNTHESIS;

3 AMINO 5 HYDROXYBENZOIC ACID DERIVATIVE; AMIDE SYNTHASE; ANSAMYCIN DERIVATIVE; HYDROXYBENZOIC ACID DERIVATIVE; NATURAL PRODUCT; POLYKETIDE; RNA 16S; UNCLASSIFIED DRUG;

BACTERIUM; CHROMATOGRAPHY; ENZYME; GENE; GENE FLOW; POLYMERASE CHAIN REACTION; SECONDARY METABOLITE;

ACTINOBACTERIA; AHBA SYNTHASE GENE; AMIDE SYNTHASE GENE; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BIOSYNTHESIS; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DRUG SCREENING; FRACTIONATION; GENE CLUSTER; GENE SEQUENCE; MICROMONOSPORA; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; POLYMERASE CHAIN REACTION; THIN LAYER CHROMATOGRAPHY;

ACTINOBACTERIA; ACTINOBACTERIA (CLASS); MICROMONOSPORA;

EID: 84879102722     PISSN: 13645072     EISSN: 13652672     Source Type: Journal    
DOI: 10.1111/jam.12217     Document Type: Article

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